Acute respiratory distress syndrome (ARDS) is a serious lung condition. It happens when the tiny air sacs in your lungs (called alveoli) become filled with fluid. Normally, these alveoli have a thin lining that protects them. But in ARDS, the lining gets damaged, and fluid leaks into the air sacs. This prevents the lungs from taking in enough air, which means less oxygen gets into your bloodstream. Without enough oxygen, your organs can't work properly.
ARDS typically affects people who are already very sick or have suffered major injuries. A key symptom is severe shortness of breath, which often develops within a few hours or a few days after the event (like an injury or infection) that caused ARDS.
Unfortunately, ARDS can be deadly. The chances of surviving ARDS are lower for older people and those with more severe cases. Even if someone does survive, some may experience lasting lung damage. While some people fully recover, others face long-term health problems related to their lungs.
Acute Respiratory Distress Syndrome (ARDS) is a serious lung condition. How bad the symptoms are depends on the cause and if you have other health problems like heart or lung disease. Key signs of ARDS include:
ARDS often develops after a major illness or injury. Most people with ARDS are already in a hospital. However, if you experience these symptoms and are not in a hospital, seek immediate medical help. Go to the nearest emergency room, or call 911 or your local emergency number. Prompt medical attention is crucial.
Acute Respiratory Distress Syndrome (ARDS) is often a complication of a serious illness or accident. Most people who develop ARDS are already being treated in a hospital. However, if you think you might have ARDS and are not in a hospital, get immediate medical help. Go to the nearest emergency room or call 911 or your local emergency number. Don't delay; prompt medical attention is crucial.
The lungs have tiny tubes called bronchioles. Air travels through these bronchioles to reach tiny air sacs called alveoli. These alveoli are like little balloons, and they're surrounded by a thin lining called the alveolar-capillary membrane. Normally, this membrane keeps fluid from the blood vessels (capillaries) from leaking into the air sacs.
Acute Respiratory Distress Syndrome (ARDS) is a serious lung problem. Several things can cause it:
Severe Infection (Sepsis): This is the most common cause. Sepsis is a very serious infection that spreads throughout the body through the bloodstream.
Serious Lung Infection (Pneumonia): If pneumonia is severe enough, it can affect all parts of the lungs.
Severe COVID-19: A severe case of COVID-19 can damage the lungs, causing swelling and making it hard to breathe. Since COVID-19 often primarily affects the respiratory system, this lung damage can lead to ARDS.
Serious Injuries: Injuries to the head, chest, or other parts of the body can damage the lungs or the part of the brain that controls breathing, potentially leading to ARDS.
Breathing in Harmful Substances: Breathing in large amounts of smoke, chemical fumes, vomit, or water (in near-drowning cases) can damage the lungs and cause ARDS.
Other Medical Problems: Other serious medical conditions, like inflammation of the pancreas (pancreatitis), very large blood transfusions, or severe burns, can also trigger ARDS.
Many people who develop Acute Respiratory Distress Syndrome (ARDS) are already in the hospital for other serious health problems. These individuals are often very sick. A major risk factor is infection, like sepsis or pneumonia. COVID-19 can also increase the risk, especially if a person also has metabolic syndrome (a group of conditions that raise the risk of heart disease, stroke, and type 2 diabetes).
Unhealthy lifestyle choices, such as heavy alcohol use, drug use, or smoking, significantly increase the chances of developing ARDS. A history of these habits puts people at higher risk for this serious lung condition. These unhealthy habits can damage the lungs and make them more vulnerable to ARDS.
Acute Respiratory Distress Syndrome (ARDS) can lead to several complications during hospitalization. These complications can include:
Blood clots: Staying in bed for extended periods, especially while on a breathing machine (ventilator), increases the risk of blood clots, particularly in the deep veins of the legs. A piece of this clot can break off and travel to the lungs, blocking blood flow. This is called a pulmonary embolism, and it can be dangerous.
Lung infections: A breathing tube inserted into the windpipe for the ventilator makes it easier for germs to infect the lungs. This can cause serious lung damage.
Scarred lungs (pulmonary fibrosis): The inflammation from ARDS can cause scarring and thickening of the tissue in the lungs. This makes the lungs less flexible, and oxygen has a harder time getting into the bloodstream. This scarring can happen relatively quickly, within a few weeks of the start of ARDS.
Stomach ulcers: Serious illness or injury triggers the stomach to produce more acid. This extra acid can irritate the stomach lining, causing ulcers.
While improved treatments mean more people are surviving ARDS, many survivors face long-term effects:
Ongoing breathing problems: While many people regain most of their lung function within several months to several years, some may experience breathing difficulties for the rest of their lives. Even those who recover well often experience shortness of breath, fatigue, and may need supplemental oxygen at home for a period of time.
Cognitive problems: The medications used to treat ARDS, along with low blood oxygen levels, can sometimes lead to memory loss and difficulty concentrating. In some cases, these cognitive problems improve over time, but in others, they may persist.
Fatigue and muscle weakness: Staying in bed for a long time, especially while on a ventilator, can weaken muscles. Many people also experience extreme tiredness after the treatment process.
It's important to remember that these potential problems are not guaranteed for every person with ARDS. Recovery varies greatly, and the severity of complications depends on individual factors.
Diagnosing Acute Respiratory Distress Syndrome (ARDS) isn't based on one specific test. Instead, healthcare providers use a combination of methods to reach a diagnosis. They rely on physical examinations, X-rays of the chest, and blood tests to measure oxygen levels. Crucially, they also need to rule out other conditions that might have similar symptoms, such as certain heart problems.
A chest X-ray helps show if there's fluid buildup in the lungs and if the heart is enlarged. This helps determine the extent of lung involvement. A more detailed picture can be obtained with a CT scan. A CT scan uses multiple X-ray images from different angles to create cross-sectional views of the organs inside the chest. This allows doctors to see the heart and lungs in detail and identify any abnormalities.
Blood tests are another important part of the diagnostic process. One type of blood test measures the amount of oxygen in your blood. Other blood tests can look for signs of infection or other illnesses that might be causing the symptoms. If a lung infection is suspected, samples of mucus from the airways might be examined to identify the specific germ causing the problem.
Since ARDS symptoms can mimic those of some heart conditions, doctors might order heart tests.
Electrocardiogram (ECG): This is a painless test that records the electrical signals generated by your heart. Small sensors attached to your skin detect these signals, providing information about your heart's rhythm and electrical activity.
Echocardiogram: This test uses sound waves to create images of your heart. These images show how blood flows through the heart's chambers and valves. Any structural changes in the heart can also be detected through this test. This helps distinguish between ARDS and heart-related issues.
Treating Acute Respiratory Distress Syndrome (ARDS) primarily focuses on getting enough oxygen into the bloodstream. Without enough oxygen, your organs can't function properly.
Doctors use several methods to increase oxygen levels:
Supplemental oxygen: For less severe cases or temporary support, a mask covering the nose and mouth delivers extra oxygen. This helps get more oxygen into the blood.
Mechanical ventilation: Most people with ARDS need a breathing machine (ventilator). The ventilator pushes air into the lungs, helping to push some of the fluid out of the tiny air sacs in the lungs (alveoli). This improves oxygen intake.
Extracorporeal Membrane Oxygenation (ECMO): If other treatments like mechanical ventilation aren't enough for severe ARDS, ECMO might be an option. ECMO is a temporary life support system. It acts like an artificial heart and lungs, taking over the job of getting oxygen into the blood and removing carbon dioxide from the blood. This allows the body's lungs to rest and heal. ECMO is a significant procedure with potential risks, so it's crucial to discuss the pros and cons with your medical team.
Prone position: For some people on mechanical ventilation, lying on their stomach (prone position) can help more oxygen reach the lungs.
Careful fluid management: Giving the right amount of intravenous (IV) fluids is very important. Too much fluid can worsen lung problems, while too little can hurt the heart and other organs.
Medications: People with ARDS typically receive medications for several reasons:
Infection prevention and treatment: Medications help prevent and treat infections that can complicate ARDS.
Pain and discomfort relief: Medications ease pain and discomfort associated with the condition.
Blood clot prevention: Medications help prevent blood clots in the legs or lungs, which can be serious.
Acid reflux management: Medications help reduce stomach acid buildup, which can be problematic in ARDS.
Anxiety and stress reduction: Medications can help manage anxiety and stress, which can be significant during a serious illness.
Lung transplant: In rare, carefully selected cases where other treatments fail, a lung transplant may be considered. This is typically for people who were otherwise healthy before developing severe ARDS. A lung transplant is a complex procedure and should only be done at a specialized center with highly experienced surgeons and transplant teams.
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