Dupilumab (subcutaneous route)
ලබා ගත හැකි වෙළඳ නාම
Dupixent
මෙම ඖෂධය ගැන
Dupilumab injection is used alone or in combination with other medicines (eg, topical corticosteroids) to treat moderate to severe atopic dermatitis in patients who have been treated with topical medicines that did not work well or who cannot use topical treatment. Dupilumab injection is also used together with other medicines to treat moderate to severe asthma in patients whose asthma is hard to control or who are dependent on steroid medicines. Dupilumab helps prevent severe asthma attacks (exacerbations) and can improve your breathing. This medicine will not relieve an asthma attack that has already started. Dupilumab injection is also used as additional treatment for chronic rhinosinusitis with nasal polyposis (CRSwNP) that is not well controlled. This medicine is also used to treat eosinophilic esophagitis (EoE) and prurigo nodularis (PN). This medicine is available only with your doctor's prescription. This product is available in the following dosage forms:
මෙම ඖෂධය භාවිතා කිරීමට පෙර
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of dupilumab injection totreat atopic dermatitis in children younger than 6 months of age, totreat asthma in children younger than 6 years of age, totreat eosinophilic esophagitis in children younger than 1 year of age and weighing less than 15 kilograms (kg), totreat chronic rhinosinusitis with nasal polyposis in children younger than 12 years of age, or totreat prurigo nodularis in children. Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of dupilumab injection in the elderly. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
මෙම ඖෂධය භාවිතා කරන ආකාරය
A nurse or other trained health professional will give you this medicine. It is given as a shot under your skin, usually in the thigh, stomach area, or upper arm. This medicine may also be given at home to patients who do not need to be in a hospital or clinic. You or your caregiver may be trained to prepare and inject the medicine at home. Be sure that you understand how to use the medicine. This medicine should come with a patient information leaflet and patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions. If you use Dupixent® at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems. Do not inject into skin areas that are tender, damaged, bruised, or scarred. This medicine is available as a prefilled pen or syringe.Use the prefilled pen only for adults and children 2 years of age and older.Use the prefilled syringe only for adults and children 6 months of age and older. Dupixent® should be given by or under the supervision of an adult in children 12 years of age and older. This medicine should be given by a caregiver in children 6 months to less than 12 years of age. Allow the medicine to warm to room temperature for 30 or 45 minutes before using it. Check the liquid in the prefilled pen or syringe. It should be clear and colorless to pale yellow. Do not use it if it is cloudy, discolored, or has particles in it. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Every week dose schedule:If you miss a dose, use a dose as soon as possible and start a new schedule from the last dose. Every other week dose schedule:If you miss a dose and it iswithin 7 daysfrom the missed dose, use a dose as soon as possible and go back to your regular dosing schedule. If you miss a dose and it ismore than 7 days, skip the missed dose and go back to your regular schedule. Every 4 weeks dose schedule:If you miss a dose and it iswithin 7 daysfrom the missed dose, use a dose as soon as possible and go back to your regular dosing schedule. If you miss a dose and it ismore than 7 days, use a dose and start a new schedule based on this date. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Store in the refrigerator. Do not freeze. Protect the medicine from direct light. Keep the medicine in the original package until you are ready to use it. You may also store the prefilled syringe or pen at room temperature for up to 14 days. Use the medicine within 14 days after removing it from the refrigerator. Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
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