C Difficile

IClostridioides difficile (klos-TRID-e-oi-deez dif-uh-SEEL) iyibhaktheriya ebangela ukutheleleka kwesisu esikhulu, ingxenye ende kunazo zonke yesisu esikhulu. Izimpawu zingase zihluke kusukela ekuvaleni kuya ekubhujisweni okubulalayo kwesisu esikhulu. Leli bhaktheriya liqanjwe ngokuthi yi-C. difficile noma i-C. diff. Ukugula okuvela ku-C. difficile kuvame ukwenzeka ngemuva kokusebenzisa imithi yebhaktheriya. Kuthinta ikakhulu abadala ezigulini noma ezindaweni zokunakekelwa kwesikhathi eside. Abantu abangasebenzi ezindaweni zokunakekelwa noma ezigulini bangathola ukutheleleka kwe-C. difficile. Ezinye izinhlobo zebhaktheriya ezingabangela ukutheleleka okukhulu zivame ukubathinta abantu abasebancane. Leli bhaktheriya laliqanjwe ngokuthi yiClostridium (klos-TRID-e-um) difficile.

Izimpawu zivame ukuqala phakathi nezinsuku eziyi-5 kuya kweziyi-10 ngemuva kokuqala ukusebenzisa i-antibiotic. Kepha izimpawu zingase zenzeke kusukela ngosuku lokuqala noma ngisho nangemva kwezinyanga ezintathu. Izimpawu ezivame kakhulu zokutheleleka okulinganiselwe yi-C. difficile yilezi: Ukuhlanza amanzi izikhathi ezintathu noma ngaphezulu ngosuku olulodwa noma ngaphezulu. Ukubamba nobuhlungu obukhulu esiswini. Abantu abane-C. difficile infection eqatha bayathanda ukulahlekelwa yi-fluid yomzimba, isimo esibizwa ngokuthi ukuphelelwa amanzi emzimbeni. Bangase badinge ukwelashwa esibhedlela ngenxa yokuphelelwa amanzi emzimbeni. Ukutheleleka yi-C. difficile kungabangela ukuvuvukala kwesisu. Ngezinye izikhathi kungakha amaqatha ethishu eluhlaza okungase igazi noma i-pus. Izimpawu zokutheleleka okukhulu zifaka: Ukuhlanza amanzi njalo njengezikhathi eziyi-10 kuya kweziyi-15 ngosuku. Ukubamba nobuhlungu esiswini, okungase kube nzima. Izinga lokugijima lenhliziyo. Ukulahlekelwa yi-fluid, okubizwa ngokuthi ukuphelelwa amanzi emzimbeni. Ukuqandisa. Ukuphefumula. Ukwanda kwenani le-white blood cell. Ukwehluleka kwesibindi. Ukulahlekelwa ukudla. Isisu esivuvukile. Ukulahlekelwa isisindo. Igazi noma i-pus emathunjini. Ukutheleleka yi-C. difficile okukhulu futhi okuzumayo kungabangela ukuvuvukala kwesisu nokukhula, okubizwa ngokuthi i-toxic megacolon. Futhi kungabangela isimo esibizwa ngokuthi i-sepsis lapho impendulo yomzimba ekuthelelekeni yonakalisa izicubu zayo. Abantu abane-toxic megacolon noma i-sepsis bamukelwa e-intensive care unit esibhedlela. Kepha i-toxic megacolon ne-sepsis azivamile ngokutheleleka yi-C. difficile. Abanye abantu bane-loose stools ngesikhathi noma ngokushesha ngemuva kokwelashwa nge-antibiotic. Lokhu kungase kubangelwe ukutheleleka yi-C. difficile. Yenza i-appointment yempilo uma une: Izitulo ezintathu noma ngaphezulu zamanzi ngosuku. Izimpawu ezihlala isikhathi esingaphezu kwezinsuku ezimbili. Ukuqandisa okusha. Ubuhlungu obukhulu noma ukubamba esiswini. Igazi emathunjini.

Abanye abantu banezinkinga zokukhuluphala ngesikhathi noma ngokushesha ngemva kokwelashwa ngama-antibiotic. Lokhu kungenzeka kubangelwe ukutheleleka yi-C. difficile. Yenza i-aphoyintimenti yempilo uma una: Izisu ezintathu noma ngaphezulu ezinamanzi ngosuku. Izimpawu ezihlala isikhathi esingaphezu kwezinsuku ezimbili. Ukuqala ukufiphaza. Ubuhlungu obukhulu esiswini noma ukubamba. Igazi emathunjini akho.

IBacteria ye-C. difficile ingena emzimbeni ngomlomo. Zingaqala ukuzala esibindini esincane. Lapho zifika engxenyeni yomthambo omkhulu, ebizwa ngokuthi i-colon, ama-bacteria angakhulula izinto eziyingozi ezilimazayo izicubu. Lezi zinto eziyingozi zibhubhisa amangqamuzana futhi zibangele ukukhipha amanzi. Ngaphandle kwe-colon, ama-bacteria awasebenzi. Angaphila isikhathi eside ezindaweni ezinjengalezi: Izisu zabantu noma zezilwane. Ubuso begumbi. Izandla ezingageziwe. Uthuli. Amanzi. Ukudla, kufaka phakathi inyama. Uma ama-bacteria ephinde athole indlela yesistimu yokugaya ukudla yomuntu, ayaqala futhi abangele ukutheleleka. Ngenxa yokuthi i-C. difficile ingaphila ngaphandle komzimba, ama-bacteria asakazeka kalula. Ukungagezi izandla noma ukuhlanza kahle kwenza kube lula ukusakaza ama-bacteria. Abanye abantu bathethela ama-bacteria e-C. difficile ezibindini zabo kodwa abalweli. Laba bantu bayizithwali zama-bacteria. Bangasakaza ukutheleleka ngaphandle kokugula.

Abantu abangenayo izingozi ezaziwayo baye bagula yi-C. difficile. Kodwa izinto ezithile zikhuphula ingozi.

Izinkinga ze-C. difficile infection zihlanganisa: Ukushonelwa amanzi, okubizwa ngokuthi ukuphelelwa amanzi. Ukulunywa okukhulu kungadala ukushonelwa amanzi kanye neziminerali ezinjengamatshe, okubizwa ngokuthi ama-electrolytes. Lokhu kwenza kube nzima emzimbeni ukusebenza njengoba kufanele. Kungabangela ukwehla kokucindezela kwegazi okungaba yingozi.Ukwehluleka kwesibindi. Kwezinye izimo, ukuphelelwa amanzi kungaba khona ngokushesha kangangokuba izinso ziyeke ukusebenza, okubizwa ngokuthi ukwehluleka kwesibindi.I-Toxic megacolon. Kulesi simo esingavamile, i-colon ayikwazi ukususa igesi ne-stool. Lokhu kwenza ikhule, okuthiwa yi-megacolon. Uma ingalashwa, i-colon ingase iqubuke.Iintsholongwane zingangena egazini. I-Toxic megacolon ingaba yingozi. Idinga ukuhlinzwa okusheshayo.Umshingo omkhulu, okuthiwa yi-bowel perforation. Lesi simo esingavamile sivela ekubhujisweni kwe-lining ye-colon noma kwenzeka ngemuva kwe-toxic megacolon. Iintsholongwane ezivela e-colon ziye endaweni engenalutho ephakathi komzimba, okuthiwa yi-abdominal cavity, zingadala ukutheleleka okubulalayo okuthiwa yi-peritonitis.Ukufa. Ukutheleleka okukhulu kwe-C. difficile kungaba yingozi ngokushesha uma kungalashwa ngokushesha. Ngokungavamile, ukufa kungase kwenzeke ngokutheleleka okulinganiselwe noma okulinganiselwe.