Esophagitis Eosinophilic

I-esophagitis iwukuvuvukala nokuvuvuka, okubizwa ngokuthi ukutheleleka, kwamaseli ahlanganisa umgudu. Umphako omde, ongagwegwanga, ophethwe ikhamera, obizwa ngokuthi i-endoscope, ungasetshenziswa ukubona ngaphakathi komgudu. Lesi sithombe se-endoscopic se-eosinophilic esophagitis sibonisa ama-rings avuvukayo e-tissue engaqondakali evela ekuthelelekeni okuqhubekayo. Aziwa ngokuthi ama-rings omgudu.

I-Eosinophilic esophagitis (e-o-sin-o-FILL-ik uh-sof-uh-JIE-tis) yisifo esingapheli sesistimu yokuphepha. Nalesi sifo, uhlobo lweselula elimhlophe legazi, elibizwa ngokuthi yi-eosinophil, lakha ngaphakathi komgca womphako ohlanganisa umlomo wakho nesisu sakho. Lo mphako ubizwa nangokuthi umgudu. Lokhu kukwakha, okuyisici sezinto zokudla, izinto ezingavumelekile noma ukubuyela emuva kwesisu, kungavuvukala noma konakalise i-tissue yomgudu. I-tissue yomgudu eyonakele ingabangela ubunzima bokuginya noma ibangela ukuba ukudla kunamathele uma uginya.

I-Eosinophilic esophagitis iye yaqaphelwa kuphela kusukela ekuqaleni kwawo-1990, kodwa manje kubhekwa njengesizathu esikhulu sesifo sesistimu yokugaya. Ucwaningo luyaqhubeka futhi cishe luzoletha ukulungiswa ekuxilongweni nasekwelapheni kwe-eosinophilic esophagitis.

Izimpawu nezimpawu zihlanganisa: Abadala: Ubunzima bokuginya, okuthiwa yi-dysphagia Ukudla okuvalekile esibindini emva kokugwinya, okwaziwa nangokuthi impaction Ubuhlungu obusengqabeni obuvamise ukuba phakathi futhi obungaphenduli kuma-antacids Ukubuyela emuva kokudla okungagayiwe, okuwaziwa ngokuthi regurgitation Abantwana: Ubunzima bokuhlala bepheka, kubantwana abasebancane Ubunzima bokudla, kubantwana Ukugabha Ubuhlungu besisu Ubunzima bokuginya, okuthiwa yi-dysphagia Ukudla okuvalekile esibindini emva kokugwinya, okwaziwa nangokuthi impaction Ayikho impendulo kwimithi ye-GERD Ukwehluleka kokukhula, okuhlanganisa ukukhula okubi, ukondleka okubi nokulahlekelwa isisindo Funani usizo lwezokwelapha ngokushesha uma uhlushwa ubuhlungu obusengqabeni, ikakhulu uma futhi une-shortness of breath noma ubuhlungu emaxebeni noma engalweni. Lezi zingaba izimpawu zokuhlushwa yisifo senhliziyo. Yenza i-aphoyintimenti nodokotela wakho uma uhlushwa izimpawu ezinzima noma ezivamile ze-eosinophilic esophagitis. Uma uthatha imithi engayona yemithi yokuhlanza inhliziyo ngaphezu kabili ngesonto, bona udokotela wakho.

Funani usizo lwezokwelapha ngokushesha uma uhlushwa ubuhlungu ebeleni, ikakhulu uma futhi unethukutheki lokuphefumula noma ubuhlungu emaxwini noma engalweni. Lezi zingaba izimpawu zokuhlushwa yisifo senhliziyo. Yenza i-aphoyintimenti nodokotela wakho uma uhlushwa izimpawu ezinzima noma ezivame kakhulu ze-eosinophilic esophagitis. Uma uthatha imithi engayona imithi yokwelapha ngaphezulu kabili ngesonto, bona udokotela wakho.

Amaseliophils uhlobo oluvamile lwamaseli egazi amhlophe atholakala esiswini sakho. Kodwa-ke, ku-eosinophilic esophagitis, uba nokuqina okungokwempilo kwento engaphandle. Ukusebenzisana kungase kwenzeke ngale ndlela elandelayo:

• Ukusebenzisana kwesisu. Ukugqoka kwesisu sakho kuya kuqina ngezinto ezingqina ukungezwani, njengokudla noma i-pollen.
• Ukukhula kwamaseliophils. Amaseliophils ayakhuphuka esiswini sakho futhi akhiqize iprotheni ebangela ukuvuvukala.
• Ukonakala kwesisu. Ukuvuvukala kungabangela ukwenziwa kwamabala, ukuncipha nokwakhiwa kwezicubu eziningi zefayibha ekugqokeni kwesisu sakho.
• I-Dysphagia nokuvalela. Ungase ube nobunzima bokuginya, okuthiwa yi-dysphagia. Noma ukudla kungase kubambe lapho uginya. Lokhu kuwaziwa ngokuthi ukuvalela.
• Izimpawu ezengeziwe. Ungase ube nezinye izimpawu, njengokuhlunguluka kwesifuba noma emathunjini.

Kube khona ukwanda okukhulu kwabanabantu abaxilongwe nge-eosinophilic esophagitis kuleli khulu leminyaka eledlule. Ekuqaleni, abacwaningi bacabanga ukuthi lokhu kwakubangelwa ukwanda kolwazi phakathi kwabahlinzeki bezempilo nokutholakala okukhulu kwezivivinyo. Kodwa-ke, izifundo manje zikhomba ukuthi isifo siyakhula, sihambisana nokukhula kwe-asthma ne-allergies.

Lezi zinto zilandelayo zifakwe ezingozini zokuthola i-eosinophilic esophagitis:

• Isimo sezulu. Abantu abahlala ezindaweni ezibandayo noma ezomileyo banesilinganiso esiphezulu sokuxilongwa yi-eosinophilic esophagitis kunalabo abahlala kwezinye izindawo.
• Isizini. Kunesilinganiso esiphezulu sokuxilongwa phakathi kwenkathi yentwasahlobo nokuwa, mhlawumbe ngoba amazinga ompunga nezinye izinto ezingabangela ukuqina kwesisu aphezulu futhi abantu banesilinganiso esiphezulu sokuphuma ngaphandle.
• Ubulili. I-eosinophilic esophagitis ivame kakhulu kubantu besilisa kunabesifazane.
• Umlando womndeni. Abacwaningi bacabanga ukuthi i-eosinophilic esophagitis ingaba nezingxenyekazi zezinto eziyizofuzo ngoba lesi simo ngezinye izikhathi sivela emindenini. Uma amalungu omndeni wakho enayo i-eosinophilic esophagitis, unesilinganiso esiphezulu sokuxilongwa.
• Uketshezi no-Asthma. Uma une-allergies yokudla noma yezinto ezingaphandle, i-asthma, i-atopic dermatitis, noma isifo sempilo sokuphefumula esiqhubekayo, unesilinganiso esiphezulu sokuxilongwa yi-eosinophilic esophagitis.
• Ubudala. Ekuqaleni, i-eosinophilic esophagitis yayicatshangelwa njengesifo sabantwana, kodwa manje kuyaziwa ukuthi ivame nakwabantu abadala. Izimpawu zihluke kancane phakathi kwabantwana nabantu abadala.

Kubantu abathile, i-eosinophilic esophagitis ingabangela lokhu okulandelayo:

• Ukulimala nokuncipha komlomo wesifuba. Lokhu kwenza kube nzima ukugwinya futhi kwenze kube lula ukubambezeleka kokudla.
• Ukonakala komlomo wesifuba. Ngenxa yokuvuvukala komlomo wesifuba, i-endoscopy ingabangela ukuqhekeka noma ukukhishwa kwesikhumba esigubungela umlomo wesifuba. Ukuqhekeka kungase kwenzeke futhi ngokuhambisana nokugabha okubhekene nabanye abantu lapho ukudla kubambezeleka emgomweni wesifuba.

Ukubuka ngaphakathi komzimba Khulisa isithombe Valela Ukubuka ngaphakathi komzimba Ukubuka ngaphakathi komzimba Phakathi nokubuka ngaphakathi komzimba oluphezulu, ochwepheshe bezempilo ufake ithyube elithambile, elikhulu, elihlanganiswe nokukhanya nekhamera phansi komlomo bese uya esibindini. Ikhamera encane inikeza umbono wesibindini, isisu, nokuqala kwesibindini esincane, okuthiwa yi-duodenum. Umhlinzeki wakho wezempilo uzobheka kokubili izimpawu zakho nemiphumela yokuhlola ukuze aqonde ukutheleleka kwe-eosinophilic esophagitis. Lokhu kuzoba yilapho unquma khona ukuthi une-gastroesophageal reflux disease (GERD). Izivivinyo zokuxilonga ukutheleleka kwe-eosinophilic esophagitis zihlanganisa: Ukubuka ngaphakathi komzimba oluphezulu. Umhlinzeki wakho uzosebenzisa ithyube elide, elincinyane (endoscope) eliqukethe ukukhanya nekhamera encane bese uyifaka ngomlomo wakho phansi esibindini. Ukuqina kwesibindini sakho kuzohlolwa ukuze kubonwe ukuvuvukala nokuqina, izinhlangothi eziqondile, imigodi emikhulu, ukuncipha (izicubu), namabala amhlophe. Abanye abantu abane-eosinophilic esophagitis bazoba nesibindini esibukeka siqondile. I-Biopsy. Phakathi nokubuka ngaphakathi komzimba, kuzokwenziwa i-biopsy yesibindini sakho. I-biopsy ihilela ukuthatha ingxenye encane yethishu. Izibonelo zethishu eziningi zizokuthathwa esibindini sakho bese ziphenyiselwa ngaphansi komkhiqizo we-microscope we-eosinophils. Izivivinyo zegazi. Uma kukhona ukutheleleka kwe-eosinophilic esophagitis, ungase ube nezilingo ezingeziwe ukuze uqinisekise ukuxilongwa. Lezi zilingo zibheka imithombo yokusabela kwakho okungokwe-allergic, okuthiwa yi-allergens. Ungase unikezwe izivivinyo zegazi ukuze ubone ukuthi inani le-eosinophil liphezulu kunokujwayelekile noma amazinga e-immunoglobulin E aphelele, okubonisa ukungezwani. Isiponji sesibindini. Lo mkhuba wenziwa ehhovisi lomhlinzeki wezempilo. Kuhilela ukugwinya ikhaphsuli ehlotshaniswe nentambo. Ikhaphsuli izoncishiswa esiswini sakho bese ikhipha isiponji esizosikwa umhlinzeki emlonyeni wakho ngentambo. Njengoba isiponji sisuswa, sizokhetha izicubu zesibindini. Lokhu kuvumela umhlinzeki wakho ukuthi aqonde izinga lokuvuvukala esibindini sakho ngaphandle kokubuka ngaphakathi komzimba. Ukukhathalela eMayo Clinic Iqembu lethu lochwepheshe beMayo Clinic elinakekelayo lingakusiza ngezinkinga zakho zempilo ezihlobene ne-eosinophilic esophagitis Qala lapha Ulwazi oluthe xaxa Ukukhathalela kwe-eosinophilic esophagitis eMayo Clinic Izivivinyo ze-allergy zesikhumba Ukubuka ngaphakathi komzimba oluphezulu

I-Eosinophilic esophagitis kubhekwa njengesiifo esingapheli esiphindaphindayo, okusho ukuthi abantu abaningi bazodinga ukwelashwa okuqhubekayo ukuze baqede izimpawu zabo. Ukwelashwa kuzoba yilokhu okulandelayo noma ngaphezulu kwalokho: Ukwelashwa kokudla Ngokuya ngendlela obuyisile ngayo ekuhlolweni kokudla okubangela ukwanda kokuvuvukala, umhlinzeki wakho wezempilo angakuncoma ukuba uyeke ukudla ukudla okuthile. Ukuqeda ukudla okuthile, njengoba nje imikhiqizo yobisi noma yengqolowa, kungasiza ekuqedeni izimpawu nokunciphisa ukuvuvukala. Ngezinye izikhathi, kungase kunconywe ukunciphisa ukudla kwakho nakakhulu. Imithi I-proton pump inhibitor (PPI). Umhlinzeki wakho cishe uzokuqala ukubhalela i-acid blocker efana ne-PPI. Lokhu ukwelashwa kulula kakhulu ukusebenzisa, kodwa izimpawu zabantu abaningi azithuthuki. I-Topical steroid. Uma ungaphenduli kwi-PPI, umhlinzeki wakho uzokubhalela i-steroid, njenge-fluticasone noma i-budesonide. Le steroid isefomeli yensipho eselulwa ukwelapha i-eosinophilic esophagitis. Lolu hlobo lwe-steroid aluthathwa ngegazi, ngakho-ke akunakwenzeka ukuthi ube nemiphumela emibi evame ukuxhumene ne-steroids. Ama-monoclonal antibodies. I-Food and Drug Administration (FDA) yakamuva yamukele i-dupilumab (Dupixent) yokwelapha abantu abadala nabantwana abaneminyaka engu-12 nangaphezulu abane-eosinophilic esophagitis. I-Dupilumab uhlobo lwemiyekezo olukwaziwa ngokuthi yi-monoclonal antibody. Isebenza ekuvimbeni ukusebenza kwamapuroteni athile emzimbeni abangela ukuvuvukala. I-Dupilumab inikezwa masonto onke ngokuqhafaza. Ukuqina Uma uhlushwa ukungapheli okukhulu, okwaziwa ngokuthi yi-stricture, yesophagus yakho, umhlinzeki wakho angakuncoma ukuqina. Ukuqina, okubizwa nangokuthi ukwelula, kungasiza ekwenzeni kube lula ukugwinya. Ukuqina kungase kusetshenziswe uma i-steroids ayisizi. Noma ukuqina kungaba ukukhetha ukuze ugweme ukusetshenziswa okuqhubekayo kwemithi. Cela i-aphoyintimenti Kukhona inkinga ngolwazi oluvezwe ngezansi bese uthumela kabusha ifomu. Thola ulwazi lwakamuva lwezempilo kusuka eMayo Clinic oluthunyelwa ebhokisini lakho le-imeyili. Bhalisa mahhala bese uthola umhlahlandlela wakho ojulile ngesikhathi. Chofoza lapha ukuze uthole i-imeyili yokubuka kuqala. Ikheli le-imeyili Iphutha Ibhokisi le-imeyili liyadingeka Iphutha Faka ikheli le-imeyili elisebenzayo Ikheli 1 Bhalisa Funda kabanzi ngokusetshenziswa kwe-Mayo Clinic idatha. Ukuze sikunikeze ngolwazi olufanele kakhulu noluncedo, nokuqonda ukuthi yiluphi ulwazi olusizo, singahlanganisa i-imeyili yakho nolwazi lokusetshenziswa kwewebhusayithi nolunye ulwazi esinalo ngawe. Uma ungumguli we-Mayo Clinic, lokhu kungafaka ulwazi oluvikelwe lwezempilo. Uma sihlanganisa lolu lwazi nolwazi lwakho oluvikelwe lwezempilo, sizophatha lonke lolu lwazi njengolwazi oluvikelwe lwezempilo futhi sizosebenzisa noma sizoveze lolu lwazi kuphela njengoba kuchazwe esazisweni sethu semikhuba yobumfihlo. Ungakhetha ukungatholi i-imeyili nganoma yisiphi isikhathi ngokuqhafaza isixhumanisi sokuyeka ukubhalisa kwi-imeyili. Siyabonga ngokubhalisa Umhlahlandlela wakho ojulile wezempilo yokugaya ukudla uzoba ebhokisini lakho le-imeyili maduze. Uzophinde uthole ama-imeyili kusuka eMayo Clinic ngezindaba zakamuva zezempilo, ucwaningo, nokunakekelwa. Uma ungayitholi i-imeyili yethu ngaphakathi kwemizuzu emi-5, hlola ifolda yakho ye-SPAM, bese usithinta [email protected]. Uxolo, kukhona okuphuthumayo ngokubhalisa kwakho Sicela uzame futhi ngemizuzu embalwa Uzama kabusha