Dabigatran (indlela yokumunca ngomlomo)
Imikhiqizo etholakalayo
Pradaxa
Mayelana naleli khambi
UDabigatran usetshenziswa ukunciphisa ingozi yokubeletha nokuqina kwegazi kubantu abane-rhythm yenhliziyo enkulu ebizwa ngokuthi i-atrial fibrillation engavalelwe yi-valve. UDabigatran futhi usetshenziswa ukwelapha nokuvimbela ukuqina kwegazi (isib. i-deep vein thrombosis, i-pulmonary embolism) ukuthi kwenzeke futhi kubantu abake bamukele eminye imithi. Kusetshenziswa futhi ukuvimbela i-deep vein thrombosis ne-pulmonary embolism ngemva kokuthi kwenziwe ubuyekezo be-hip. Isebenza ngokuvimbela ukuqina okubi ukuba kuqale emathanjeni egazi. Lolu dokotela lutholakala kuphela ngomyalo wodokotela. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqululo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqhelile noma oluhambisana nokwaleka kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokwaleka, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela ye-dabigatran capsules noma ama-pellets omhlathi kubantwana abanezinhlungu zenhliziyo noma ababekhulu ukufakwa kwesihlakala. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantwana ezingalinda ukusetshenziswa kwe-dabigatran capsules kubantwana abaneminyaka engu-8 nangaphezulu noma ama-dabigatran oral pellets kubantwana abaneminyaka engaphansi kwengu-12 ubudala abanezinhlungu zokugqwala kwegazi. Ukuphepha nokuphumelela kuye kwaqinisekiswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-dabigatran kubantu abadala. Noma kunjalo, iziguli ezikhulile zinezinkinga zokuqala ezihlobene nobudala, ukuphuza igazi, noma izinkinga zezinkalankala, okungase kudinge ukunakekela nokulungiswa komthamo kwabaguli abamukela i-dabigatran. Ayikho izifundo ezifanele kwabesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo imithi ehlukene emibili ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlu lwezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayikhuthazwa. Udokotela wakho anganquma ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayikhuthazwa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma kokubili imithi. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo kungabangela ingozi eyenyuka yezinye izingozi ezibekiwe, kodwa ukusebenzisa kokubili imithi kungaba ukwelashwa okuhle kuwe. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma kokubili imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba ngezinye izidakamizwa kungabangela ukuhlangana. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha lo muthi ngqo njengoba kuyalelwe ngudokotela wakho. Ungathathi okuningi kakhulu, ungathathi kaningi, futhi ungathathi isikhathi eside kunalokho udokotela akubekele kona. Ukwenza kanjalo kungadala ukuthi kube namathuba amaningi okuthola imiphumela emibi. Futhi, ungayeki ukusebenzisa lo muthi ngaphandle kokubheka kuqala nodokotela wakho. Lo muthi uza negama lomuthi. Kubaluleke kakhulu ukuthi ufunde futhi uqonde lolu lwazi. Qiniseka ukubuza udokotela wakho uma unemibuzo. Ungathatha lo muthi noma ngaphandle kokudla. Gwinya ikhapule ngokuphelele ngegilasi eligcwele lamanzi. Ungayicindezeli, ungayihlehlisi, ungayihlafuni, noma ungayivuli. Uma uthatha omunye umuthi wokuncipha igazi, (isb, heparin, warfarin, Coumadin®), udokotela wakho uzokunikeza imiyalelo ethile mayelana nokuthi ungashintsha kanjani ukuya ku-dabigatran. Landela ngokucophelela imiyalelo futhi ubuze udokotela wakho uma unemibuzo. Ukusebenzisa ama-pellets omunye: Uma uthatha lo muthi izikhathi ezimbili ngosuku, thatha isilinganiso esisodwa ekuseni nesinye ebusuku, okungenani amahora angu-12 ehlukene. Thatha ngesikhathi esifanayo nsuku zonke. Isilinganiso salo muthi sizohluka kubaguli abahlukene. Landela imiyalelo kadokotela wakho noma izinkomba ezikwilebula. Ulwazi olulandelayo luhlanganisa kuphela izilinganiso ezijwayelekile zalo muthi. Uma isilinganiso sakho sihlukile, ungasisintshi ngaphandle kokuthi udokotela akutshele ukuthi usenze kanjalo. Inani lomuthi othatha lincike eqinweni lomuthi. Futhi, inani lezilinganiso ozithatha nsuku zonke, isikhathi esivunyelwe phakathi kwezilinganiso, kanye nesikhathi eside osithatha umuthi sincike enkingeni yezempilo obusebenzisa umuthi ngayo. Uma uphuthelwa yisilinganiso salo muthi, thatha ngokushesha ngangokunokwenzeka. Kodwa-ke, uma sekuseduze nesikhathi sesilinganiso sakho esilandelayo, yeqa isilinganiso esilahlekile bese ubuyela ohlelweni lwakho lokuthatha izilinganiso. Ungathathi izilinganiso eziphindwe kabili. Uma unesikhathi esingaphansi kwama-6 amahora ngaphambi kwesilinganiso sakho esilandelayo, yeqa isilinganiso esilahlekile bese ubuyela ohlelweni lwakho lokuthatha izilinganiso. Uma uthathe ingxenye kuphela yesilinganiso sakho sama-pellets omunye, ungathathi esinye isilinganiso ngokushesha. Thatha isilinganiso sakho esilandelayo ohlelweni lwakho lokuthatha izilinganiso, okungenani amahora angu-12 kamuva. Gcina ingaphathi kwabantwana. Ungagcini umuthi ophelelwe yisikhathi noma umuthi ongasadingeki. Buza ochwepheshe bezempilo ukuthi kufanele ulahle kanjani noma yimuphi umuthi ongawusebenzisi. Gcina umuthi esitsheni esivalekile endaweni yokuhlala, kude nomlilo, umswakama, nokukhanya okuqondile. Gcina ungafrizi. Gcina umuthi wakho epaketheni lokuqala (ipakethe le-blister noma ibhodlela lama-khapule noma isaka le-aluminium lamaphakethe ama-pellets omunye) kuze kube yilapho usuzolisebenzisa. Ungagcini ama-khapule kunoma yisiphi esinye isitsha (isb, amabhokisi wamaphilisi noma abahleli bamaphilisi). Ngemuva kokuvula ibhodlela okokuqala, kufanele uthathe wonke ama-khapule ngaphakathi kwezinyanga ezi-4. Uma ungakasebenzisi ama-khapule ngaphakathi kwezinyanga ezi-4, kufanele ulahle ama-khapule asele bese uqala ibhodlela elisha. Sebenzisa iphakethe ngalinye lama-pellets omunye ngaphakathi kwezinyanga ezi-6 zokuvula isaka le-aluminium. Lahla noma yimuphi umuthi ongasawusebenzisi. Ungagcini futhi uphinde usebenzise noma yimuphi umxube osalele.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.