Yini i-Eflapegrastim-xnst: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Eflapegrastim-xnst iyimithi esiza umzimba wakho ukuthi ukhiqize amaseli amaningi amhlophe egazi lapho ukwelashwa komdlavuza kuye kwenza buthaka amasosha akho omzimba. Lolu uhlobo olusha lwe-growth factor olusebenza isikhathi eside emzimbeni wakho kunezindlela zokwelapha ezindala ezifanayo, okusho ukuthi ngokuvamile udinga imijovo embalwa.

Le mithi ingeyeqembu elibizwa ngokuthi ama-long-acting granulocyte colony-stimulating factors. Cabanga ngayo njengomsizi okhuluma nomnkantsha wakho ukuthi ukhiqize amaseli amaningi alwa nezifo lapho i-chemotherapy inciphise okwesikhashana inani lawo.

Isetshenziselwani i-Eflapegrastim-xnst?

I-Eflapegrastim-xnst isetshenziswa ikakhulukazi ukuvimbela izifo ezingathi sína kubantu abathola i-chemotherapy yomdlavuza. Lapho i-chemotherapy ibhubhisa amaseli omdlavuza, inganciphisa okwesikhashana inani lamaseli akho amhlophe egazi, ikushiye ubhekane nezifo.

Udkt wakho ngokuvamile uzokunikeza le mithi uma uthola i-chemotherapy eyaziwa ukuthi ibangela ukwehla okukhulu kwenani lamaseli amhlophe egazi. Ilusizo ikakhulukazi kubantu abathola ukwelashwa okubeka engozini enkulu yesimo esibizwa ngokuthi i-febrile neutropenia, lapho inani eliphansi lamaseli amhlophe egazi liholela emkhuhlaneni nasezifweni ezingathi sína ezingenzeka.

Le mithi isetshenziswa futhi uma usuvele uhlangabezane namanani aphansi amaseli amhlophe egazi emijikelezweni yangaphambilini ye-chemotherapy. Lokhu kusiza ukuvimbela le nkinga ukuthi ingenzeki futhi ngokwelashwa okuzayo.

Isebenza kanjani i-Eflapegrastim-xnst?

I-Eflapegrastim-xnst isebenza ngokukhuthaza umnkantsha wakho ukuthi ukhiqize amaseli amaningi amhlophe egazi, ikakhulukazi ama-neutrophil. Lawa ngumugqa wakho wokuqala wokuzivikela ezifweni zamagciwane.

Umuthi uthathwa njengowelapha onamandla futhi osebenzayo ngoba wenzelwe ukuhlala isikhathi eside emzimbeni wakho kunezinhlobo ezindala. Lesi senzo esandisiwe sisho ukuthi singanikeza ukuvikeleka kuyo yonke imijikelezo yakho ye-chemotherapy ngokujova okukodwa nje ngomjikelezo wokwelashwa.

Umgqondo wakho wamathambo uphendula lo muthi ngokukhulisa ukukhiqizwa kwamaseli amasha egazi elimhlophe. Le nqubo ngokuvamile ithatha izinsuku ezimbalwa ukukhombisa imiphumela, yingakho isikhathi esihle neshejuli yakho ye-chemotherapy kubalulekile.

Kufanele Ngiyithathe Kanjani I-Eflapegrastim-xnst?

I-Eflapegrastim-xnst inikezwa njengomjovo ongaphansi kwesikhumba, okusho ukuthi ijovwa ngaphansi kwesikhumba kunokuba ingene emthanjeni. Umhlinzeki wakho wezempilo uzokunikeza umjovo, ngokuvamile engalweni yakho engenhla, ethangeni, noma esiswini.

Isikhathi sibalulekile ukuze lo muthi usebenze kahle. Ngokuvamile uzothola umjovo amahora angu-24 kuya kwangu-72 ngemuva kokuthi ukwelashwa kwakho kwe-chemotherapy kuphele, kodwa ungalokothi ngaphakathi kwamahora angu-24 ngaphambi kokuthi iseshini yakho elandelayo ye-chemotherapy iqale.

Akudingeki ukuthi uthathe lo muthi ngokudla noma ugweme ukudla ngaphambi komjovo. Kodwa-ke, ukuhlala unamanzi kahle nokugcina ukudla okunempilo kungasiza umzimba wakho ukuthi uphendule kangcono ekwelashweni.

Abanye abantu bazwa ukungakhululeki okuncane endaweni yokujova. Ukusebenzisa i-compress ebandayo ngemuva komjovo kungasiza ukunciphisa noma yikuphi ukuqaqamba noma ukuvuvukala.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Eflapegrastim-xnst?

Ubude bokwelashwa kwe-eflapegrastim-xnst buxhomeke eshedyulini yakho ethile ye-chemotherapy nokuthi umzimba wakho uphendula kanjani. Abantu abaningi bathola umjovo owodwa ngomjikelezo ngamunye we-chemotherapy, okungasho ukwelashwa ezinyangeni eziningana.

Udokotela wakho uzoqapha ukubalwa kwamaseli akho egazi elimhlophe kuyo yonke imithi ukuze anqume ukuthi udinga ukuqhubeka yini nomuthi. Uma ukubala kwakho kululama kahle futhi kuhlala kuzinzile, ungase ungakudingi kuwo wonke umjikelezo.

Abanye abantu badinga lo muthi imijikelezo embalwa ye-chemotherapy kuphela, kanti abanye bayawudinga kuyo yonke imithi yabo yomdlavuza. Ithimba lakho lezempilo lizohlola njalo ukuthi ngabe izinzuzo zisaqhubeka yini ukwedlula noma yimaphi imiphumela emibi.

Yini Imiphumela Emiqoka Ye-Eflapegrastim-xnst?

Njengayo yonke imithi, i-eflapegrastim-xnst ingabangela imiphumela emibi, yize abantu abaningi beyibekezelela kahle. Imiphumela emibi ejwayelekile ivame ukuba mnene futhi ilawuleka.

Nansi imiphumela emibi ongase ube nayo, futhi kujwayelekile ngokuphelele ukuba nokunye kwalokhu okwenzekayo njengoba umzimba wakho uzivumela:

• Ubuhlungu bamathambo noma ubuhlungu bemisipha, ikakhulukazi emhlane wakho, ezingalweni, nasemilenzeni
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile
• Ikhanda
• Ukucasuka noma isisu esicasukile
• Ubuhlungu, ububomvu, noma ukuvuvukala endaweni yokujova
• Isiyezi

Ubuhlungu bamathambo buvela ngoba umnkantsha wakho usebenza kanzima ukuze ukhiqize amaseli amhlophe egazi amaningi. Lokhu kungakhululeki kuvame ukuthuthuka ezinsukwini ezimbalwa futhi kungalawulwa ngemithi yokwelapha ubuhlungu etholakala ngaphandle kwekhawunta uma udokotela wakho ekugunyaza.

Imiphumela emibi engavamile kodwa ebucayi idinga ukunakekelwa kwezempilo ngokushesha. Ngenkathi lokhu kungavamile, kubalulekile ukwazi ukuthi yini okufanele uyibheke:

• Ubuhlungu obukhulu bamathambo obungathuthuki ngemithi yokwelapha ubuhlungu
• Izimpawu zokungezwani komzimba njengokuqubuka, ukuluma, noma ubunzima bokuphefumula
• Ukuphuma kwegazi okungajwayelekile noma ukulimala
• Ubuhlungu obukhulu besisu
• Ukuphefumula kanzima noma ubuhlungu besifuba

Ngokungavamile, abanye abantu bangase babe nesimo esibizwa nge-tumor lysis syndrome noma izinkinga ngesibindi sabo. Ithimba lakho lezempilo lizokuqapha ngokucophelela ukuze uthole lezi zinkinga ezingavamile.

Ubani Ongafanele Athole I-Eflapegrastim-xnst?

I-Eflapegrastim-xnst ayilungelwe wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Ezinye izimo noma izimo zenza lo muthi ungafaneleki noma uyingozi.

Akufanele usebenzise i-eflapegrastim-xnst uma wazi ukuthi unokungezwani komzimba nalo muthi noma imithi efanayo ebizwa ngokuthi i-filgrastim noma i-pegfilgrastim. Udokotela wakho uzophinda aqaphele uma unezifo ezithile zegazi noma isifo se-sickle cell.

Abantu abanezinhlobo ezithile zomdlavuza wegazi, ikakhulukazi lezo ezithinta ngqo amaseli amhlophe egazi, kungenzeka bangabi ngabazongenela lo muthi. Udokotela wakho we-oncologist uzoqaphela ukuthi ngabe uhlobo lwakho oluthile lomdlavuza lwenza i-eflapegrastim-xnst ingafaneleki.

Uma ukhulelwe noma uncelisa, udokotela wakho uzoqaphela izinzuzo uma ziqhathaniswa nezingozi ezingaba khona. Umuthi kungenzeka usadingeka uma wamukela i-chemotherapy esindisa impilo, kodwa lokhu kudinga ukucatshangelwa ngokucophelela.

Amagama Omkhiqizo we-Eflapegrastim-xnst

I-Eflapegrastim-xnst itholakala ngaphansi kwegama lomkhiqizo elithi Rolvedon. Leli yigama lezentengiso ozolibona kulebula lakho likanhlama kanye nokupakishwa komuthi.

Ingxenye ethi "xnst" yegama ikhomba ukuthi lo ngumuthi we-biosimilar, okusho ukuthi ufana kakhulu neminye imithi yokukhula kodwa unezici ezithile eziyingqayizivele eziwenza uhlale isikhathi eside emzimbeni wakho.

Ezinye Izindlela ze-Eflapegrastim-xnst

Eminye imithi eminingi isebenza ngendlela efanayo ne-eflapegrastim-xnst ukuze ikhulise inani lamaseli amhlophe egazi ngesikhathi se-chemotherapy. Udokotela wakho angase acabangele lezi ezinye izindlela ngokusekelwe ezidingweni zakho ezithile kanye nomshwalense.

I-Filgrastim (Neupogen) iyinhlobo esebenza isikhashana edinga imijovo yansuku zonke kunokuba umjovo owodwa ngomjikelezo. Ngenkathi isebenza, ayilula ngoba udinga imijovo evame kakhulu.

I-Pegfilgrastim (Neulasta) enye inketho esebenza isikhathi eside esebenza ngendlela efana ne-eflapegrastim-xnst. Udokotela wakho angakhetha phakathi kwalezi ngokusekelwe ekuphenduleni kwakho ukwelashwa kanye nanoma yimaphi imiphumela emibi oyitholayo.

I-Lipegfilgrastim (Lonquex) enye enye indlela esebenza isikhathi eside ohlelweni lwakho. Ngamunye wale mikhiqizo yemithi unezici ezehlukile kancane, futhi ithimba lakho lezempilo lizosiza ukunquma ukuthi yini ekusebenzela kangcono.

Ingabe i-Eflapegrastim-xnst ingcono kune-Pegfilgrastim?

Kokubili i-eflapegrastim-xnst ne-pegfilgrastim ziyimithi esebenza isikhathi eside esebenzayo ethuthukisa ukubalwa kwamangqamuzana amhlophe egazi ngesikhathi se-chemotherapy. Ucwaningo lubonisa ukuthi zisebenza kahle ngendlela efanayo ekuvikeleni izifo nasekugcineni ukubalwa kwamangqamuzana egazi.

Inzuzo enkulu ye-eflapegrastim-xnst ukuthi ingase ihlale isikhathi eside ohlelweni lwakho, okungenzeka ukuthi inikeze ukuvikelwa okuqhubekayo ngesikhathi somjikelezo wakho we-chemotherapy. Abanye abantu futhi bathola izindlela zokuphendula ezimbalwa zesayithi yokujova nge-eflapegrastim-xnst.

Nokho, i-pegfilgrastim isetshenziswe isikhathi eside futhi inemininingwane eminingi yocwaningo etholakalayo. Udokotela wakho uzocabangela izinto ezinjengokuthi umshwalense wakho umboza kanjani, izimpendulo zangaphambilini emithini efanayo, kanye nohlelo lwakho oluthile lwe-chemotherapy lapho ekhetha phakathi kwazo.

Zombili le mithi idinga ukujova okukodwa kuphela ngomjikelezo ngamunye we-chemotherapy, okwenza kube lula kunokunye ukujova kwansuku zonke. Ukukhetha kuvame ukwehla ezintweni zomuntu ngamunye nokuthi yini esebenza kangcono esimweni sakho esithile.

Imibuzo Evame Ukubuzwa Nge-Eflapegrastim-xnst

Ingabe i-Eflapegrastim-xnst iphephile kubantu abanezifo zenhliziyo?

I-Eflapegrastim-xnst ngokuvamile ithathwa njengephephile kubantu abanezifo zenhliziyo, kodwa i-cardiologist yakho kanye ne-oncologist kuzodingeka basebenze ndawonye ukuze bakuqaphele ngokucophelela. Umuthi ngokwawo awuthinti ngokuqondile inhliziyo yakho, kodwa ukucindezeleka kokwelashwa komdlavuza okuhlanganiswe nanoma yimuphi umuthi kudinga ukugadwa ngokucophelela.

Uma unomlando wezinkinga zenhliziyo, ithimba lakho lezokwelapha cishe lizokuqapha ngokucophelela ngezinguquko esimweni sakho senhliziyo nemithambo yegazi. Bangase balungise uhlelo lwakho lokwelashwa noma banikeze ukunakekelwa okwengeziwe kokusekela ukuqinisekisa ukuthi inhliziyo yakho ihlala izinzile ngesikhathi sokwelashwa.

Kufanele ngenzeni uma ngithola i-Eflapegrastim-xnst eningi ngengozi?

Uma usola ukuthi uthole i-eflapegrastim-xnst eningi, xhumana nomhlinzeki wakho wezempilo ngokushesha, ngisho noma uzizwa kahle. Njengoba lo muthi unikezwa ochwepheshe bezempilo, ukweqisa akavamile, kodwa amaphutha angenzeka.

Izimpawu zomuthi omningi zingabandakanya ubuhlungu obukhulu emathanjeni, ukubala okuphezulu kakhulu kwamaseli amhlophe egazi, noma izimpawu ezingavamile njengobuhlungu bekhanda obukhulu noma izinguquko embonweni. Udokotela wakho cishe uzofuna ukuqapha ukubalwa kwegazi lakho kaningi futhi angase anikeze ukunakekelwa okusekelayo ukuphatha noma yiziphi izimpawu.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Eflapegrastim-xnst?

Uma uphuthelwa umjovo wakho ohleliwe, xhumana nomhlinzeki wakho wezempilo ngokushesha ngangokunokwenzeka ukuze uhlele kabusha. Isikhathi salo muthi sibalulekile ukuvikela ngesikhathi somjikelezo wakho we-chemotherapy.

Ungazami ukwenza umthamo ophuthelwe ngokuthola imijovo emibili eduze. Udokotela wakho uzonquma inkambo engcono kakhulu yesenzo ngokusekelwe lapho ukhona emjikelezweni wakho we-chemotherapy nokuthi isikhathi esingakanani sesidlulile kusukela kumthamo wakho ophuthelwe.

Ngingayeka nini ukuthatha i-Eflapegrastim-xnst?

Ungayeka ukuthatha i-eflapegrastim-xnst lapho udokotela wakho enquma ukuthi akusadingeki, ngokuvamile uma usuqedile ukwelashwa kwakho kwe-chemotherapy noma uma ukubalwa kwamaseli akho amhlophe egazi kuhlala kuzinzile ngaphandle kwayo.

Abanye abantu badinga lo muthi kuphela imijikelezo embalwa ye-chemotherapy, kanti abanye bayawudinga kuyo yonke indlela yokwelashwa kwabo. Ithimba lakho lezempilo lizobuyekeza njalo ukubalwa kwegazi lakho kanye nokuphendula kwakho konke ukuze linqume ukuthi kuphephile nini ukuyeka umuthi.

Ngingahamba yini ngenkathi ngithatha i-Eflapegrastim-xnst?

Ngokuvamile ungaqhubeka nohambo lwakho ngenkathi uthola i-eflapegrastim-xnst, kodwa kuzodingeka ukuthi ubambisane nethimba lakho lezempilo ukuze uqinisekise ukuthi ungazithola ngesikhathi esifanele imijovo yakho. Uma uhamba ngenkathi uthola i-chemotherapy, ithimba lakho lezokwelapha lizokusiza ukuthi ulungiselele ukwelashwa lapho uya khona noma lilungise isheduli yakho ngokufanele.

Khumbula ukuthi amasosha akho omzimba angase abe buthakathaka okwesikhashana ngesikhathi se-chemotherapy, ngakho udokotela wakho angase ancome ukugwema izindawo ezigcwele abantu noma ukuthatha izinyathelo ezengeziwe zokuzivikela ezifweni ngenkathi uhamba. Hlala uxoxa ngezinhlelo zokuhamba nomhlinzeki wakho wezempilo ngaphambi kokwenza amalungiselelo.