Yini i-Famciclovir: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Famciclovir iyikhambi elilwa namagciwane elisiza umzimba wakho ukuthi ulwe nezifo ezithile ezibangelwa amagciwane, ikakhulukazi lezo ezibangelwa amagciwane e-herpes. Yilokho odokotela abakubiza ngokuthi “i-prodrug,” okusho ukuthi iguquka ibe yifomu layo elisebenzayo uma ingena emzimbeni wakho, lapho ingase iqale ukusebenza ivimbela amagciwane ukuthi azande.

Cabanga nge-famciclovir njengomsizi oqondiwe oqondiswe ngqo e-herpes simplex virus (HSV) kanye ne-varicella-zoster virus (VZV). Nakuba ingakwazi ukwelapha lezi zifo ngokuphelele, inganciphisa kakhulu ukuthi uhlangabezana isikhathi esingakanani nezimpawu futhi isize ekuvikeleni ukuqubuka okuzayo.

Yini i-Famciclovir Esetshenziselwa Yona?

I-Famciclovir iphatha izinhlobo eziningana zezifo ezibangelwa amagciwane, ezivame kakhulu lezo ezihilela amagciwane e-herpes. Udokotela wakho angase akubhalele uma ubhekene nezilonda ebandayo, i-genital herpes, noma i-shingles.

Umuthi usebenza kahle kakhulu ekwelapheni ukuqubuka okukhulu kwe-genital herpes, usiza ukunciphisa ubuhlungu, ukuluma, nesikhathi esithathayo ukuthi izilonda ziphole. Iphinde isebenze ekuphatheni izigameko eziphindaphindayo, futhi abantu abaningi bathola ukuthi izimpawu zabo zincipha ngokuhamba kwesikhathi.

Nge-shingles (herpes zoster), i-famciclovir ingasiza ukunciphisa ubuhlungu obukhulu bemizwa futhi isheshise inqubo yokuphola. Ngokushesha uqala ukuyithatha ngemva kokuba izimpawu zivele, iba yiphumelela kakhulu.

Udokotela wakho angase futhi akubhalele i-famciclovir ukusiza ekuvikeleni ukuqubuka kwe-herpes okuzayo, ikakhulukazi uma uhlangabezana nakho kaningi. Le ndlela, ebizwa ngokuthi i-suppressive therapy, inganciphisa kakhulu ukuthi ukuqubuka kwenzeka kaningi kangakanani.

Isebenza Kanjani i-Famciclovir?

I-Famciclovir ingeyeqembu lemithi ebizwa ngokuthi ama-nucleoside analogs, futhi isebenza ngokuphazamisa indlela amagciwane azala ngayo. Uma uthatha umuthi, umzimba wakho uguqula ube yi-penciclovir, okuyifomu elisebenzayo elilwa ngempela igciwane.

Umuthi oguquliwe umuncwa ngamaseli anegciwane futhi uvimba i-enzyme ebizwa nge-DNA polymerase edingwa amagciwane ukuze azikopishe. Ngaphandle kokuthi le enzyme isebenza kahle, igciwane alikwazi ukwenza amakhophi amasha awo, okusiza ukumisa ukuthi ukutheleleka kungasakazeki kumaseli anempilo.

Njengomuthi olwa namagciwane, i-famciclovir ithathwa njengemoderali futhi isebenza kahle kakhulu ezintweni ezihloselwe zona. Ayinamandla njengeminye imithi elwa namagciwane emisha, kodwa inerekhodi elihle lokwelapha izifo ze-herpes ezinemiphumela embalwa.

Umuthi usebenza kahle kakhulu uma uqala ukuwuthatha ngokushesha nje lapho uqaphela izimpawu ziqala. Abantu abaningi bafunda ukuqaphela ukuzwa ukuluma noma ukusha kwasekuqaleni okubonisa ukuthi ukuqubuka kuyaqala, futhi ukuthatha i-famciclovir kulesi sigaba kunganciphisa kakhulu ubukhulu nobude bezimpawu.

Kufanele Ngiyithathe Kanjani I-Famciclovir?

Ungathatha i-famciclovir ngaphandle noma ngaphandle kokudla, njengoba ukudla kungayithinti ngendlela ebonakalayo indlela umzimba wakho omunca ngayo umuthi. Kodwa-ke, ukuyithatha nokudla okulula noma ukudla okulula kungasiza ukunciphisa noma yikuphi ukuphazamiseka kwesisu ongase ukuzwe.

Into ebaluleke kakhulu ukuthatha i-famciclovir ngendlela eqondile udokotela wakho ayikuyale ngayo, ngisho noma uqala ukuzwa ngcono ngaphambi kokuthi uqede wonke amaphilisi. Ukuyeka umuthi ngokushesha kakhulu kungavumela igciwane ukuthi libuyele emuva liqine.

Qiniseka ukuthi uphuza amanzi amaningi ngenkathi uthatha i-famciclovir ukusiza izinso zakho ukucubungula umuthi ngempumelelo. Ukuhlala unamanzi kahle kuyindlela enhle ngaso sonke isikhathi uma uthatha noma yimuphi umuthi, kodwa kubaluleke kakhulu ngemithi elwa namagciwane.

Uma unenkinga yokugwinya amaphilisi, ungaqhekeza phakathi, kodwa ungaqedi noma uwahlafune. Umuthi wenzelwe ukuba umuncwe ngendlela ethile, futhi ukushintsha ithebhulethi kakhulu kungase kuthinte ukuthi isebenza kahle kangakanani.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Famciclovir?

Ubude bokwelashwa nge-famciclovir buxhomeke esimweni osilaphayo nokuthi umzimba wakho usabela kanjani emuthini. Ezifweni eziningi ezingamahlalakhona ezinjengokuqubuka kwe-herpes noma i-shingles, ukwelashwa kuvame ukuthatha phakathi kwezinsuku eziyi-7 kuya kweziyi-10.

Uma uthatha i-famciclovir ngokuqubuka kokuqala kwe-genital herpes, udokotela wakho cishe uzoyibhala izinsuku eziyi-7 kuya kweziyi-10. Ekuqubukeni okuphindaphindayo, isikhathi sokwelashwa singaba sifushane, ngokuvamile cishe izinsuku ezi-5, njengoba amasosha akho omzimba esivele ejwayelene nokulwa ngegciwane.

Nge-shingles, inkambo yokwelashwa ejwayelekile yizinsuku eziyi-7, kodwa lokhu kunganwetshwa kube yizinsuku eziyi-10 kuye ngokuthi izimpawu zakho zinzima kangakanani nokuthi uqale ngokushesha kangakanani ukwelashwa ngemuva kokuthi ukuqubuka kuvele.

Abanye abantu basebenzisa i-famciclovir ekwelashweni okucindezelayo kwesikhathi eside ukuvimbela ukuqubuka okuvamile. Kulezi zimo, ungase uthathe umthamo ophansi wansuku zonke izinyanga noma iminyaka, ngokuhlolwa okuvamile ukuqapha ukuthi ukwelashwa kusebenza kahle kangakanani nokuthi ngabe uhlangabezana nanoma yimaphi imiphumela emibi.

Yiziphi Imiphumela Eceleni ye-Famciclovir?

Abantu abaningi bayayibekezelela kahle i-famciclovir, kodwa njenganoma imuphi umuthi, ingabangela imiphumela emibi kwabanye abantu. Izindaba ezinhle ukuthi imiphumela emibi engathí sina ayivamile, futhi abantu abaningi bathola kuphela izimpawu ezilula uma zikhona.

Nawa imiphumela emibi evame kakhulu ongase uyithole ngenkathi uthatha i-famciclovir:

• Ikhanda elibuhlungu, elivame ukuba lula futhi livame ukunyamalala njengoba umzimba wakho ujwayela umuthi
• Ukucasuka noma ukungakhululeki kwesisu, ikakhulukazi uma uthatha umuthi esiswini esingenalutho
• Ukuqunjelwa noma izitulo ezixekethile, ezivame ukuxazululwa ezinsukwini ezimbalwa
• Isiyezi noma ukuzwa ukukhanya ekhanda, ikakhulukazi lapho usukuma ngokushesha
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile

Lezi zimo ezivamile ezithinta umzimba ngokuvamile ziyalawuleka futhi zivame ukuthuthuka njengoba ukwelashwa kwakho kuqhubeka. Uma ziba yizinkinga, khuluma nodokotela wakho mayelana namaqhinga okuzinciphisa.

Nakuba kungavamile, abanye abantu bangase babe nemiphumela emibi kakhulu edinga ukunakekelwa kwezempilo. Lezi zimpendulo ezingavamile zihlanganisa:

• Ukungezwani komzimba okukhulu ngezimpawu ezinjengobunzima bokuphefumula, ukuvuvukala kobuso noma umphimbo, noma ukuqubuka okukhulu
• Ushintsho olungavamile esimweni sengqondo, njengokudideka noma ukucabanga okungamanga, ikakhulukazi ezigulini ezindala noma lezo ezinezinkinga zezinso
• Izimpawu zezinkinga zezinso njengokuncipha komchamo, ukuvuvukala emilenzeni noma ezinyaweni, noma ukukhathala okungavamile
• Ukuphendula kwesikhumba okukhulu, okuhlanganisa ukuqubuka okubuhlungu noma ukuqhekeka

Uma uhlangabezana nanoma yiziphi zalezi zimpawu ezingathi sína, xhumana nomhlinzeki wakho wezempilo ngokushesha noma funa ukunakekelwa kwezimo eziphuthumayo. Nakuba lezi zimpendulo zingavamile, kubalulekile ukuzazi ukuze ukwazi ukuthola usizo ngokushesha uma kudingeka.

Ubani Ongafanele Athathe I-Famciclovir?

I-Famciclovir ayifaneleki kuwo wonke umuntu, futhi zikhona izimo ezithile lapho udokotela wakho angase akhethe omunye umuthi kuwe. Okubaluleke kakhulu ukuthi ngabe uke waba nokungezwani komzimba ne-famciclovir noma imithi efanayo esikhathini esidlule.

Uma unezinkinga zezinso, udokotela wakho uzodinga ukulungisa umthamo wakho noma akuqaphele eduze ngenkathi uthatha i-famciclovir. Njengoba izinso zakho zinesibopho sokuqeda umuthi emzimbeni wakho, ukuncipha komsebenzi wezinso kungabangela ukuthi umuthi wakheke emazingeni angaba yingozi.

Abantu abanezifo zesibindi kufanele futhi basebenzise i-famciclovir ngokucophelela, njengoba izinkinga zesibindi zingathinta indlela umzimba wakho osebenza ngayo umuthi. Udokotela wakho angase adinge ukuqala ngomthamo ophansi noma ahlolisise ukusebenza kwesibindi sakho kaningi.

Uma ukhulelwe noma uncelisa, xoxa ngezingozi nezinzuzo nodokotela wakho. Nakuba i-famciclovir ngokuvamile ithathwa njengephephile kunezifo ezingelashwa ze-herpes ngesikhathi sokukhulelwa, umhlinzeki wakho wezempilo uzofuna ukulinganisa izinzuzo ezingaba khona ngokumelene nanoma yiziphi izingozi ezingenzeka kuwe nomntwana wakho.

Iziguli ezigugile zingase zizwele kakhulu imiphumela ye-famciclovir, ikakhulukazi mayelana nemiphumela engaba khona ekusebenzeni kwezinso kanye nokucaca kwengqondo. Udokotela wakho angase anqume umthamo ophansi noma akuqaphele eduze uma uneminyaka engaphezu kwengama-65.

Amagama Omkhiqizo we-Famciclovir

I-Famciclovir itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Famvir iyilena eqashelwa kakhulu. Leli yigama lomkhiqizo wokuqala lapho umuthi waqala ukuthengiswa futhi usaqhubeka nokunqunywa kabanzi namuhla.

Ungase futhi uthole i-famciclovir itholakala njengomuthi ojwayelekile, oqukethe isithako esifanayo esisebenzayo njengama-brand-name kodwa ngokuvamile ibiza kancane. I-Famciclovir ejwayelekile isebenza ngempumelelo njengama-brand-name futhi kufanele ihlangabezane nezindinganiso ezifanayo zekhwalithi.

Abakhiqizi abahlukene bangase bakhiqize izinguqulo ezivamile ze-famciclovir, ngakho ukubukeka kwamaphilisi akho kungase kuhluke kuye ngokuthi iyiphi ikhemisi oyisebenzisayo. Nokho, isithako esisebenzayo nokusebenza kahle kuhlala kuhambisana kungakhathaliseki ukuthi ngubani umkhiqizi.

Lapho ukhuluma ngemithi yakho nodokotela wakho noma usokhemisi, ungabhekisa emuthini ngegama lawo elivamile (famciclovir) noma igama lomkhiqizo (Famvir), futhi bazoqonda kahle ukuthi ukhuluma ngani.

Ezinye izindlela ze-Famciclovir

Eminye imithi eminingi elwa namagciwane ingelapha izimo ezifanayo ne-famciclovir, futhi udokotela wakho angase acabangele lezi ezinye izindlela ngokusekelwe esimweni sakho esithile, umlando wezokwelapha, noma ukuthi uyibekezelela kangakanani imithi ehlukene.

I-Acyclovir cishe iyona ndlela eyaziwa kakhulu futhi empeleni yayiyilapho lokuqala elisebenzayo lokwelapha amagciwane ezifo ze-herpes. Isebenza ngendlela efana ne-famciclovir kodwa idinga ukuthathwa kaningi usuku lonke, okuthile abantu abakuthola kungalula.

I-Valacyclovir enye inketho ehlobene eduze enikeza lula lokuthathwa kaningi, okufana ne-famciclovir. Odokotela abaningi bayibheka njengokufana nokusebenza kahle, futhi ukukhetha phakathi kwe-famciclovir ne-valacyclovir kuvame ukuncika ezintweni zomuntu ngamunye njengezindleko, umshwalense, noma ukubekezelelana komuntu siqu.

Kubantu abangakwazi ukuthatha imithi yomlomo, ukwelashwa okungaphezulu njenge-acyclovir cream noma i-penciclovir cream kungaba izinketho zokwelapha izilonda ezibandayo, nakuba lokhu ngokuvamile kungasebenzi kahle kunemithi yokulwa namagciwane yomlomo.

Udokotela wakho uzokusiza ukuthi unqume ukuthi iyiphi imithi yokulwa namagciwane engcono kakhulu esimweni sakho esithile, kucatshangelwa izinto ezinjengomsebenzi wezinso zakho, eminye imithi oyithathayo, kanye nemigomo yakho yokwelashwa.

Ingabe i-Famciclovir Ingcono Kune-Acyclovir?

Kokubili i-famciclovir ne-acyclovir ziyimithi yokulwa namagciwane esebenzayo, kodwa ngamunye unezici ezingenza enye ifaneleke kakhulu esimweni sakho esithile. Akukho noyedwa oncono kunomunye, kodwa kunezinye izinto ezingokoqobo okufanele zicatshangelwe.

Inzuzo enkulu ye-Famciclovir ukulula, njengoba ngokuvamile udinga ukuyithatha izikhathi ezimbili noma ezintathu ngosuku uma kuqhathaniswa neshejuli yokuthatha i-acyclovir izikhathi ezinhlanu ngosuku. Lokhu kungenza kube lula ukunamathela ohlelweni lwakho lokwelashwa, ikakhulu uma unendlela yokuphila ematasa noma uthambekele ekukhohlweni imithi.

I-Acyclovir isikhona isikhathi eside futhi inerekhodi elibanzi lokusetshenziswa, okuthile odokotela neziguli abakuthola kuqinisekisa. Futhi ngokuvamile ayibizi kakhulu kune-famciclovir, okungaba yinto ebalulekile okufanele icatshangelwe uma ukhokha ngaphandle noma unama-copays aphezulu emithi.

Ngokuqondene nokusebenza, womabili amakhambi asebenza kahle ekwelapheni izifo ze-herpes, futhi izifundo azikazange zibonise umehluko omkhulu ngokushesha lapho esusa izimpawu noma ukuvimbela ukuqubuka okuzayo. Umzimba wakho ungase usabele kangcono kancane komunye noma komunye, kodwa lokhu ngokuvamile kuyinto ongayithola kuphela ngokuhlangenwezwa.

Ukukhetha phakathi kwe-famciclovir ne-acyclovir kuvame ukwehla ezintweni ezingokoqobo njengokulula kokulinganisa, izindleko, kanye nokubekezelelana kwakho komuntu ngamunye ngamunye umuthi. Udokotela wakho angakusiza ukuthi ulinganise lezi zinto ngokusekelwe ezidingweni zakho kanye nezimo zakho.

Imibuzo Evame Ukubuzwa Mayelana ne-Famciclovir

Ingabe i-Famciclovir iphephile kubantu abane-Kidney Disease?

I-Famciclovir ingasetshenziswa ngabantu abane-kidney disease, kodwa idinga ukuqapha okucophelelayo nokulungiswa kwemithamo. Njengoba izinso zakho zinesibopho sokuqeda i-famciclovir emzimbeni wakho, ukuncipha komsebenzi wezinso kusho ukuthi umuthi ungenza ukwakheka emazingeni aphezulu kunalawo okuhlosiwe.

Udokotela wakho cishe uzo-oda ukuhlolwa kwegazi ukuze ahlolisise ukusebenza kwezinso zakho ngaphambi kokuqala i-famciclovir futhi angaqhubeka nokuqapha ngesikhathi sokwelashwa kwakho. Bazophinda futhi banikeze umthamo ophansi noma banwebe isikhathi phakathi kwemithamo ukuze bavimbele umuthi ukuthi ungaqongeleli emazingeni angaba yingozi.

Uma une-kidney disease enzima noma use-dialysis, udokotela wakho angase akhethe omunye umuthi oqeda amagciwane noma alungise isimiso sakho se-famciclovir ukuze siqondane nokwelashwa kwakho kwe-dialysis. Okubalulekile ukuxhumana okuvulekile nethimba lakho lezempilo mayelana nempilo yakho yezinso.

Ngingenzani uma ngiphuthelwa ngokungenhloso ngithatha i-Famciclovir eningi kakhulu?

Uma ngengozi uthatha i-famciclovir eningi kakhulu kunaleyo ebekiwe, ungesabi, kodwa thatha isinyathelo ngokushesha. Xhumana nodokotela wakho, usokhemisi, noma isikhungo sokulawula ubuthi ngokushesha ukuze uthole isiqondiso sokuthi wenzeni ngokulandelayo.

Ukuphuza i-famciclovir eningi ngokweqile kungase kubangele imiphumela emibi eyengeziwe, ikakhulukazi isicanucanu, ukuhlanza, ikhanda elibuhlungu, noma ukudideka. Ezimweni ezingavamile, imithamo ephezulu kakhulu ingase ithinte ukusebenza kwezinso noma ibangele izimpawu ezingathi sína ze-neurological.

Uma ucela usizo, yiba nebhodlela lomuthi nawe ukuze ukwazi ukunikeza imininingwane ethile mayelana nokuthi ungakanani owuphuze nini. Lolu lwazi luzosiza abahlinzeki bezempilo ukuthi bakunikeze iseluleko esifanele kakhulu esimweni sakho.

Ungazami ukuthi "umelane" nomuthi owengeziwe ngokuqaqa imithamo yesikhathi esizayo, ngoba lokhu kungaphazamisa uhlelo lwakho lokwelashwa. Kunalokho, landela isiqondiso osithola kubahlinzeki bezempilo mayelana nendlela yokuqhubeka nohlelo lwakho olujwayelekile lokulinganisa.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Famciclovir?

Uma uphuthelwa umthamo we-famciclovir, uwuphuze ngokushesha nje lapho ukhumbula, ngaphandle kwalapho sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kuleso simo, weqa umthamo ophuthelwe bese uqhubeka nohlelo lwakho olujwayelekile lokulinganisa.

Ungaphuzi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi ngaphandle kokunikeza inzuzo eyengeziwe. Kungcono ukugcina amazinga aqhubekayo omuthi ohlelweni lwakho kunokudala iziqongo nemigodi.

Uma uvame ukukhohlwa ukuphuza umuthi wakho, cabangela ukusetha izikhumbuzi ocingweni lwakho noma usebenzise umhleli wamaphilisi ukukusiza ukuthi uhlale emkhondweni. Ukulinganisa okuqhubekayo kubalulekile ukuze i-famciclovir isebenze ngempumelelo ekulweni nezifo ezibangelwa amagciwane.

Uma uphuthelwa imithamo eminingi noma unokukhathazeka mayelana nendlela imithamo ephuthelwe engase ithinte ngayo ukwelashwa kwakho, xhumana nodokotela wakho ukuze uthole isiqondiso. Bangakusiza ukuthi ubuyele emkhondweni ngohlelo lwakho lomuthi.

Ngingayeka nini ukuphuza i-Famciclovir?

Kufanele uqede lonke uhlelo lwe-famciclovir olwalunqunywe udokotela wakho, ngisho noma uqala ukuzizwa ungcono ngaphambi kokuthi uqede wonke amaphilisi. Ukuyeka imithi ngaphambi kwesikhathi kungavumela igciwane ukuthi libe sebenzayo futhi, okungenzeka kuholele ekubuyeni kwezimpawu.

Ezifweni ezinzima njengokuqubuka kwe-herpes noma i-shingles, ngokuvamile uzothatha i-famciclovir ngenani lezinsuku elinqunyiwe (ngokuvamile izinsuku eziyi-7-10) bese uyeka. Udokotela wakho uzokwazisa ngesikhathi esiqondile lapho ebhalela umuthi wakho.

Uma uthatha i-famciclovir ngemithi yokucindezela yesikhathi eside, isinqumo sokuthi uyeke nini sinzima kakhulu futhi kufanele senziwe ngokubonisana nodokotela wakho. Abanye abantu bayazuza ekuqhubekeni nokwelashwa kokucindezela izinyanga noma iminyaka, kanti abanye bangazama ukuyeka ngemva kwesikhathi sokuqeda ukuqubuka ngempumelelo.

Ungalokothi uyeke ukuthatha i-famciclovir ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala, ikakhulukazi uma usekwelashweni kwesikhathi eside. Bangase bafune ukukuqapha nganoma yiziphi izinguquko esimweni sakho noma balungise uhlelo lwakho lokwelashwa kancane kancane.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Famciclovir?

Ngokuvamile, ukusetshenziswa kotshwala ngokulinganisela akuhlangani ngokuqondile ne-famciclovir ngendlela eyingozi. Kodwa-ke, utshwala bungathinta amasosha akho omzimba futhi bungase buphazamise ikhono lomzimba wakho lokulwa nokutheleleka ngegciwane olikwelaphayo.

Utshwala bungase futhi lenze kube kubi eminye yemiphumela engemihle ongase uyithole ku-famciclovir, njengokuphatheka kabi ikhanda, isicanucanu, noma ikhanda. Uma usuvele uzizwa ungaphilile ngenxa yokutheleleka ngegciwane, ukwengeza utshwala emxube kungase kukwenze uzizwe uqhubeka nokuba kubi.

Uma ukhetha ukuphuza utshwala ngenkathi uthatha i-famciclovir, yenza kanjalo ngokulinganisela futhi unake indlela umzimba wakho osabela ngayo. Abanye abantu bathola ukuthi utshwala bubenza bazizwe bekhathele noma benesicanucanu uma bethatha imithi elwa namagciwane.

Uma ungabazi, ngaso sonke isikhathi kungcono ukubuza udokotela wakho noma usokhemisi mayelana nokusetshenziswa kotshwala ngemithi yakho ethile. Bangakunikeza iseluleko esiqondene nawe ngokusekelwe esimweni sakho sempilo kanye neminye imithi ongase uyithathe.