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Iritis

Overview

The middle layer of your eye, called the uvea, is located beneath the white part (sclera). It has three main parts:

  1. The iris, the colored part of your eye that surrounds the pupil.
  2. The ciliary body, which makes the clear fluid that fills the front part of your eye.
  3. The choroid, a layer of blood vessels between the sclera and the light-sensitive part of your eye (retina).

Iritis is when the iris (the colored part of your eye) becomes swollen and irritated. This is also known as anterior uveitis. Essentially, it's inflammation in the front part of the uvea.

Iritis is a common type of uveitis. Uveitis is inflammation in any part or all of the uvea. Often, doctors don't know what causes uveitis. It might be linked to an underlying health problem or even be hereditary.

If iritis isn't treated, it can lead to problems like glaucoma (increased pressure in the eye) or vision loss. It's very important to see a doctor right away if you think you might have iritis. Symptoms could include eye pain, redness, blurry vision, or sensitivity to light.

Symptoms

Inflammation of the colored part of the eye (iris), called iritis, can affect one or both eyes. It typically comes on quickly and usually resolves within three months.

Common signs of iritis include:

  • Redness in the eye: The affected eye might look red or inflamed.
  • Eye pain or discomfort: You might feel a dull ache or a sharp pain in your eye.
  • Light sensitivity: Bright light might feel very uncomfortable or painful.
  • Blurred or decreased vision: You might have trouble seeing clearly.

Iritis can develop suddenly over a few hours or days (acute iritis). Or, it can develop more gradually and last longer than three months (chronic iritis).

If you notice any of these symptoms, it's crucial to see an eye doctor (ophthalmologist) right away. Early treatment is important to prevent potential problems. If you have severe eye pain, vision changes, or other concerning symptoms, seek immediate medical attention. Prompt treatment can help prevent long-term eye damage.

When to see a doctor

If you're experiencing eye pain and vision problems, along with other symptoms like those of iritis, it's crucial to see an eye doctor (ophthalmologist) right away. Early treatment is very important to avoid more serious eye issues down the road. If your eye pain is severe, or if you have other significant vision problems or symptoms, you may need immediate medical attention.

Causes

Understanding Iritis: Causes and Connections

Iritis, a condition affecting the eye, often has no clear cause. However, several factors can be linked to it. Sometimes, it's a result of something that happened to the eye, a genetic tendency, or an underlying health issue.

Possible Causes:

  • Eye Injuries: Physical damage to the eye, like a blow, a poke, or a chemical burn, can trigger iritis. This is often a sudden onset of the problem.

  • Infections: Certain viral infections can affect the eye. For example, cold sores and shingles, which are caused by the herpes virus, can sometimes cause iritis. Other infections, such as:

    • Toxoplasmosis: An infection often spread by eating undercooked meat or contact with cat feces.
    • Histoplasmosis: A lung infection caused by inhaling fungus spores.
    • Tuberculosis: A lung infection caused by bacteria.
    • Syphilis: A sexually transmitted infection caused by bacteria. These infections can sometimes lead to a broader eye inflammation called uveitis, which is related to iritis.
  • Genetic Factors: Sometimes, a person's genes might make them more likely to develop certain autoimmune diseases, which can cause iritis. Autoimmune diseases are when the body's immune system mistakenly attacks healthy tissues. Examples include:

    • Ankylosing spondylitis: A type of arthritis that affects the spine.
    • Reactive arthritis: A type of arthritis that can follow an infection elsewhere in the body.
    • Inflammatory bowel disease (IBD): Conditions like Crohn's disease and ulcerative colitis that affect the digestive system.
    • Psoriatic arthritis: A type of arthritis that often occurs with psoriasis, a skin condition.
  • Behçet's Disease: This is a rare condition that causes inflammation in various parts of the body, including the eyes, joints, and mouth. It's a possible cause of iritis.

  • Juvenile Rheumatoid Arthritis: Children with this condition can develop long-term (chronic) iritis.

  • Sarcoidosis: This is an autoimmune disease where inflammation occurs in different parts of the body, sometimes including the eyes.

  • Medications: Some medications, such as certain antibiotics and antiviral drugs (especially those used to treat HIV), can sometimes cause iritis. Stopping these medications often resolves the issue. Also, rarely, bisphosphonates used to treat osteoporosis can cause eye inflammation.

Important Note: Many cases of iritis don't have a clear cause. If you experience eye pain or other symptoms, it's crucial to see a doctor to get a proper diagnosis and treatment.

Risk factors

Iritis, an eye inflammation, can be more likely if you have certain factors in your life. Understanding these factors can help you talk to your doctor about your risk.

Genetics: Some people inherit a gene variation that makes them more prone to iritis. This variation, called HLA-B27, is linked to a higher risk. Essentially, this means a particular genetic code might increase your susceptibility to the condition. This doesn't mean everyone with HLA-B27 will get iritis, but it does raise the chances.

Infections: Certain infections, like syphilis and HIV/AIDS, can significantly increase the risk of iritis. These infections can affect the body's immune system, potentially leading to inflammation in the eye.

Weakened Immune System or Autoimmune Diseases: If your immune system is already compromised or if you have an autoimmune disorder (like ankylosing spondylitis or reactive arthritis), you may be more vulnerable to iritis. Autoimmune disorders are conditions where the immune system mistakenly attacks healthy tissues in the body. This can lead to inflammation throughout the body, including the eyes.

Smoking: Studies show a connection between smoking and a higher chance of developing iritis. Smoking is harmful to the body in many ways and this is another reason why quitting is important.

In short, having a genetic predisposition, certain infections, a weakened immune system, or smoking can all increase your risk of getting iritis. If you have any of these factors, it's important to discuss them with your eye doctor.

Complications

Untreated iritis can cause several problems with your eye.

  • Cataracts: If iritis isn't managed well, especially if the inflammation lasts a long time, it can lead to cataracts. A cataract is like a clouding of the lens inside your eye, making it harder to see clearly.

  • Pupil Problems: The inflammation can cause scar tissue to form. This scar tissue can make the colored part of your eye (the iris) stick to the lens or the front clear part of your eye (the cornea). This can cause the pupil to become an unusual shape and make it harder for your eye to react to changes in light.

  • Corneal Problems: Iritis can also lead to calcium deposits on the cornea. This can damage the cornea and eventually lead to vision loss.

  • Retinal Swelling: Iritis can cause swelling and fluid-filled sacs (cysts) to form in the retina, the light-sensitive layer at the back of your eye. This swelling can blur or reduce the sharpness of your central vision.

Diagnosis

During a complete eye exam, your eye doctor will do several things to check your eye health.

First, a quick look: The doctor will use a small light to check your pupils, look for any redness or discharge, and check for any other visible problems with your eye. This is called the external examination.

Next, checking your vision: The doctor will use an eye chart and other standard tests to measure how clearly you can see. This is called testing your visual acuity. A clear and sharp vision is important for everyday tasks like reading and driving.

A closer look inside: Your doctor might use a special microscope with a light (a slit lamp) to examine the inside of your eye. This helps them look closely for any signs of inflammation, like iritis. Sometimes, eye drops are used to widen your pupils (making them larger), which gives the doctor a better view of the inside of your eye.

If something is suspected: If the doctor finds something unusual or thinks a disease might be causing iritis (inflammation of the eye), they will likely work with your primary care doctor to figure out the cause. This is important because iritis can sometimes be a symptom of other health problems. To figure out the cause, they might do extra tests, like blood tests or X-rays. These tests can help them find out if there's an underlying cause and what it might be.

Treatment

Treating iritis focuses on saving your vision and easing pain and swelling. If iritis is linked to another health problem, treating that problem is also crucial.

Usually, iritis treatment involves:

  • Steroid eye drops: These drops contain special medicines called glucocorticoids that help reduce the inflammation in your eye. Think of them as anti-inflammatory medicine for your eye.

  • Pupil-dilating eye drops: These drops widen your pupil. This can help decrease the pain of iritis. Widening your pupil also helps prevent potential problems that could affect how your pupil works.

If the eye drops aren't enough to clear up your symptoms or if they get worse, your eye doctor might suggest taking medicine by mouth. This medicine could include steroids or other anti-inflammatory drugs. The type of medicine and dose will depend on your overall health.

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Disclaimer: August is a health information platform and its responses don't constitute medical advise. Always consult with a licenced medical professional near you before making any changes.

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