Denosumab-bbdz (subcutaneous route)

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Denosumab-bbdz injection is used to treat osteoporosis (thinning of the bones) in women who have an increased risk for fractures after menopause, and osteoporosis in men. It is given when other medicines cannot be used or after other medicines did not work well. It is also used to treat osteoporosis in patients using steroid medicines for at least 6 months. Denosumab-bbdz injection is also used to treat bone loss in males with nonmetastatic (has not spread) prostate cancer and females with nonmetastatic breast cancer who are at high risk for fracture after receiving cancer treatment. Denosumab-bbdz injection is also used to prevent bone problems in patients with multiple myeloma and bone metastases (cancer that has spread) from solid tumors. This medicine is also used to treat giant cell tumor of the bone that cannot be removed by surgery or when surgery is too risky. It is also used to treat hypercalcemia (high calcium in the blood) associated with cancer that did not respond to bisphosphonate treatment. This medicine is to be given only by or under the supervision of your doctor.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Use of denosumab-bbdz injection is not recommended in the pediatric population, except for teenagers with giant cell tumor of the bone. This medicine may cause hypercalcemia (high calcium in the blood) in children with bone problems (eg, osteogenesis imperfecta). The safety and efficacy of denosumab-bbdz for other conditions has not been established. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of denosumab-bbdz injection in the elderly. However, some elderly patients may be more sensitive to the effects of this medicine than younger adults. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: