The compounded semaglutide dosage chart converts your prescribed mg dose into units on a U100 insulin syringe based on your vial's concentration. At the most common 5 mg/ml concentration, the standard 0.25 mg starting dose is 5 units, 0.5 mg is 10 units, 1.0 mg is 20 units, 1.7 mg is 34 units, and 2.4 mg (Wegovy maximum) is 48 units. Concentrations vary by compounding pharmacy, so always verify your vial label.
Checkout this GLP-1 dose calculator for accurate insights.
The Complete Compounded Semaglutide Dose Chart
Below is the full compounded semaglutide dosage chart for the three most common compounding pharmacy concentrations. Each row shows the standard FDA-approved Wegovy titration step in mg, with the corresponding unit count on a U100 insulin syringe.
|
Dose (mg) |
2.5 mg/ml |
5 mg/ml (most common) |
10 mg/ml |
|
0.25 mg |
10 units |
5 units |
2.5 units |
|
0.5 mg |
20 units |
10 units |
5 units |
|
1.0 mg |
40 units |
20 units |
10 units |
|
1.7 mg |
68 units |
34 units |
17 units |
|
2.0 mg (Ozempic max) |
80 units |
40 units |
20 units |
|
2.4 mg (Wegovy max) |
96 units |
48 units |
24 units |
Here is what to know up front about this semaglutide units chart. The formula is: Units = (mg dose ÷ concentration) × 100. The 5 mg/ml concentration is the most common in US compounding pharmacies as of 2026. The FDA-approved maximum is 2 mg per week for Ozempic and 2.4 mg per week for Wegovy. Doses above 2.4 mg are not FDA-approved and have limited long-term safety data. The math follows FDA Wegovy prescribing information. For broader conversion logic, see how many mg in a ml.
The Standard Semaglutide Titration Schedule
The semaglutide dosing chart follows the FDA-approved Wegovy titration schedule. Patients gradually increase the dose every 4 weeks to allow the body to adjust and minimize GI side effects.
|
Week |
Dose |
Units (5 mg/ml) |
|
Weeks 1-4 |
0.25 mg |
5 units |
|
Weeks 5-8 |
0.5 mg |
10 units |
|
Weeks 9-12 |
1.0 mg |
20 units |
|
Weeks 13-16 |
1.7 mg |
34 units |
|
Week 17+ |
2.4 mg |
48 units |
For Ozempic (type 2 diabetes), the titration is similar but maxes out at 2 mg weekly. The standard Ozempic titration moves through 0.25, 0.5, 1.0, and 2 mg weekly. For broader semaglutide dosing details, see compounded semaglutide dosage.
How to Use the Compounded Semaglutide Dose Chart
Using the semaglutide dose chart requires three pieces of information:
1. Your prescribed mg dose. This comes from your physician and follows the titration schedule. Common doses are 0.25, 0.5, 1.0, 1.7, 2.0, and 2.4 mg.
2. Your vial's concentration. This is printed on the label. Most US compounded semaglutide is dispensed at 5 mg/ml. Less common are 2.5 mg/ml and 10 mg/ml.
3. Your syringe type. All conversions on this chart assume a U100 insulin syringe (100 units per ml). If you have any other syringe, contact your pharmacy before using the chart.
Look up your dose row, find your concentration column, and read the unit count. For example, 1.0 mg at 5 mg/ml = 20 units.
The Math Behind the Chart
The compounded semaglutide dosage chart uses this formula:
Units = (mg dose ÷ concentration in mg/ml) × 100
Worked example: 1.7 mg at 5 mg/ml.
1.7 ÷ 5 = 0.34 ml 0.34 × 100 = 34 units
The same dose at 2.5 mg/ml: 1.7 ÷ 2.5 = 0.68 ml = 68 units
The same dose at 10 mg/ml: 1.7 ÷ 10 = 0.17 ml = 17 units
The volume changes with each concentration, but the mg dose stays the same. For more on the underlying math, see how many mg in a ml.
Why Concentrations Vary Across Pharmacies
Compounding pharmacies dispense semaglutide at different concentrations based on their formulation choices.
2.5 mg/ml provides good measurement precision for small doses. The starting 0.25 mg dose becomes 10 units, easier to read precisely than 5 units at 5 mg/ml.
5 mg/ml is the most common concentration in 2026. It balances volume and precision well across the entire titration range.
10 mg/ml packs more drug into less liquid, useful for higher doses. The downside is reduced precision at small doses (0.25 mg = only 2.5 units, hard to read accurately).
Different pharmacies make different choices. Always verify the concentration on your specific vial.
Reverse Conversion: Units to mg
The same chart works in reverse if you know your units and want to confirm your mg dose. For full guides, see individual articles:
-
20 units of semaglutide is how many mg
-
40 units of semaglutide is how many mg
-
50 units of semaglutide is how many mg
For an automatic calculator, use the compounded semaglutide dose calculator.
Safety Notes for Higher Doses
Doses above 2.4 mg per week are not FDA-approved. Some compounded protocols use 2.5 mg, 3 mg, or higher for patients who plateau on the maximum approved dose. These higher doses:
-
Have limited long-term safety data
-
May increase nausea, vomiting, and GI side effects
-
Carry higher risk for pancreatitis and gallbladder issues
-
Should only be used under direct physician supervision
Patients on doses above 2.4 mg should have more frequent monitoring, including blood work and physician check-ins.
Frequently Asked Questions
What is the most common compounded semaglutide concentration?
What is the most common compounded semaglutide concentration?
Most US compounding pharmacies dispense semaglutide at 5 mg/ml in 2026. Less common concentrations include 2.5 mg/ml (better for small dose precision) and 10 mg/ml (better for high doses). Always verify the concentration on your specific vial label.
How do I read the compounded semaglutide dosage chart?
How do I read the compounded semaglutide dosage chart?
Find your prescribed mg dose in the left column, then look across to your vial's concentration column. The number is your unit count on a U100 insulin syringe. For example, 0.5 mg at 5 mg/ml is 10 units.
What if my dose isn't on the chart?
What if my dose isn't on the chart?
For doses between standard titration steps, use the formula: Units = (mg ÷ concentration) × 100. For example, 0.75 mg at 5 mg/ml = 0.75 ÷ 5 × 100 = 15 units.
Can the chart be used for Ozempic or Wegovy pens?
Can the chart be used for Ozempic or Wegovy pens?
No. Ozempic and Wegovy come in pre-filled pens at fixed doses that do not require manual unit measurement. This chart is specifically for compounded semaglutide drawn from vials with insulin syringes.
Are doses above 2.4 mg safe?
Are doses above 2.4 mg safe?
The FDA-approved maximum for Wegovy is 2.4 mg per week. Doses above this are not FDA-approved and have limited long-term safety data. Some compounded protocols use higher doses for patients who plateau, but only under direct physician supervision.
Should I round to the nearest whole unit?
Should I round to the nearest whole unit?
For most doses, yes. A U100 syringe has 1-unit markings on smaller syringes (0.3 ml, 0.5 ml). For half-unit calculations like 2.5 units (0.25 mg at 10 mg/ml), draw to the nearest available marking. Ask your pharmacist if you are unsure.
