He aha te whakamātautau ENA? Te Whāinga, Ngā Taumata/Tikanga me ngā Hua

Ko te whakamātautau ENA, arā te whakamātautau Nuclear Antigen Tangohia, e tirotiro ana mō ngā paturopi motuhake ka hangaia e tō pūnaha ārai mate i te wā e whakaeke hē ana i ngā kiko o tō tinana. Mā tēnei whakamātautau toto e āwhina ngā tākuta ki te tātai i ngā āhuatanga ārai mate pēnei i te lupus, te mate a Sjögren, me te scleroderma mā te kite i ēnei paturopi motuhake i roto i ō toto.

Whakaarohia he taputapu kaitirotiro e whakaatu ana i te mea kua hē te ara o tō pūnaha ārai mate. I te wā e raruraru ana te pūnaha parenga o tō tinana, ka tīmata ki te whai i ngā pūtau hauora, ka whakaputa i ēnei paturopi motuhake ka kitea e te whakamātautau ENA.

He aha te whakamātautau ENA?

E ine ana te whakamātautau ENA i ngā paturopi ki ngā antigen karihi tangohia, arā ngā pūmua kei roto i te karihi o ō pūtau. Ka whanake ēnei paturopi i te wā e pohehe ana tō pūnaha ārai mate ki te tautuhi i ēnei pūmua noa hei riri ke.

E rapu ana te whakamātautau i ngā paturopi ki ngā pūmua matua e whai ake nei tae atu ki te Sm, RNP, SSA/Ro, SSB/La, Scl-70, me te Jo-1. Ka taea e ia o ēnei paturopi te tohu ki ngā āhuatanga ārai mate rerekē, e āwhina ana i tō tākuta ki te whakahuihui i ngā mea e tupu ana i roto i tō tinana.

Ka whiwhi te nuinga o te tangata i tēnei whakamātautau i te wā kua pai kē rātou mō te ANA (paturopi antinuclear) ā, e hiahia ana tō rātou tākuta ki te keri hōhonu ake ki te āhuatanga ārai mate motuhake pea e noho ana.

He aha te take e mahia ana te whakamātautau ENA?

Ka tono tō tākuta i tētahi whakamātautau ENA i te wā e whakaaro ana rātou kei a koe tētahi āhuatanga ārai mate, ina koa kua pā koe i ngā tohumate kāore i whakamāramahia pēnei i te mamae tahi, ngā pānga kiri, te tino ngenge rānei. Ko te nuinga o te wā ko te mahi e whai ake ana i muri i te hua whakamātautau ANA pai.

Ka tino nui te whakamātautau i te wā e whakaatu ana koe i ngā tohu ka tohu ki ētahi āhuatanga ārai mate rerekē. I te mea ka rite ngā āhuatanga nei i ō rātou wā tuatahi, ka āwhina te whakamātautau ENA ki te whāiti i ngā mea ka taea.

Koinei nga take nui e taunaki ana nga taakuta i tenei whakamatautau:

• Te mamae tahi me te pupuhi e kore e pai ake i te okiokinga
• Te pupuhi kiri kaore i whakamaramatia, ina koa ko nga pupuhi ahua pūpū i runga i nga paparinga
• Te ngenge nui e whakararu ana i nga mahi o ia ra
• Nga kanohi maroke me te waha karekau e aro ki nga rongoa noa
• Te ngoikore o te uaua, te mamae ranei kaore he take marama
• Te ahua o Raynaud (ka huri ma, kikorangi ranei nga maihao me nga matimati i te makariri)
• Nga raruraru whatukuhu kaore he whakamaramatanga
• Te kirika e hoki mai ana kaore he mate

I te mea kua korerotia, tera pea ka tono to taakuta i tenei whakamatautau mena he hitori to whanau mo nga mate autoimmune, ahakoa he ngawari noa iho o tohu. Ko te kitenga wawe ka tino rerekee te whakahaere i enei ahuatanga.

He aha te tikanga mo te whakamatautau ENA?

He ngawari noa te whakamatautau ENA, he tango toto e rima meneti noa iho hei whakaoti. Ka toro atu koe ki te taiwhanga, ki te tari ranei o to taakuta, ka kohia e tetahi tohunga hauora he tauira toto iti mai i te uaua i to ringa.

He tika tonu te mahi, he rite ki etahi atu whakamatautau toto. Ka horoi te tohunga i te waahi ki te patu huakita, ka whakauru i te ngira iti ki roto i to uaua, ka kohia te toto ki roto i te ngongo motuhake.

Anei nga mea ka tumanako koe i te wa o te tikanga:

1. Ka tonohia koe kia noho pai i roto i te tuuru me to ringa e toro ana
2. Ka herea e te tohunga he tourniquet ki to ringa o runga kia kitea nga uaua
3. Ka horoia e ratou te waahi werohanga ki te waipiro, ki te patu huakita ranei
4. Ka whakauruhia he ngira iti ki roto i to uaua (ka rongo pea koe i te wero poto)
5. Ka tangohia te toto ki roto i te kotahi, neke atu ranei nga ngongo
6. Ka tangohia te ngira ka hoatu he takai ki te waahi

He iti iho i te rima meneti te roa o te tukanga katoa, ā, ko te nuinga o te tangata e kore e nui ake te raruraru i ētahi atu whakamātautau toto. Ka taea e koe te hoki ki ngā mahi noa tonu i muri mai.

Me pēhea te whakarite mō tō Whakamātautau ENA?

Ko te rongo pai, he iti noa te whakarite e hiahiatia ana e te whakamātautau ENA i tō taha. Kāore koe e hiahia ki te nohopuku, ki te huri rānei i ō kai i mua i te whakamātautau, he mea tino watea ki te whakarite.

Ka taea e koe te kai noa, te tango i ō rongoā auau, me te haere i tō tikanga noa i mua i te whakamātautau. Heoi, he mea pai tonu te whakamōhio ki tō tākuta mō ngā rongoā katoa e tango ana koe, ina koa ngā rongoā ārai mate.

Anei ētahi mahi māmā hei āwhina i te tino pai o te wheako:

• Mau he kākahu me ngā ringaringa ka taea te huri ake
• Kia pai te wai mā te inu wai nui i mua i te whakamātautau
• Kawea mai he rārangi o ngā rongoā katoa me ngā tāpiringa e tango ana koe i tēnei wā
• Whakamōhio atu ki te tēkinihini mēnā he mataku koe ki te ngira, kua ngaro rānei te mōhiotanga i ngā wā i mua i te tango toto
• Whakaarohia te kawe mai i tētahi paramanawa mēnā ka mōrearea koe i muri i te tango toto

Mēnā he tino āwangawanga koe mō ngira, kaua e whakaroa ki te whakahua i tēnei ki te rōpū hauora. He mātanga rātou ki te āwhina i ngā tūroro e mataku ana kia pai ake te noho i te wā o te tukanga.

Me pēhea te pānui i ō Hua Whakamātautau ENA?

Ka pūrongotia ngā hua whakamātautau ENA hei pai, hei kino rānei mō ia paturopi motuhake i whakamātauria. Ko te hua kino te tikanga kāore i kitea ngā paturopi, i te mea ko te hua pai e tohu ana i te aroaro o ngā paturopi motuhake, ā, ko te tikanga kei roto he uara tau, he taitara rānei.

Ka whakamāramahia e tō tākuta ēnei hua me ō tohu, te whakamātau tinana, me ētahi atu hua whakamātautau. He mea nui kia mahara ko te whai paturopi ENA pai kāore i te kī he mate ārai-a-tinana tōu, ā, ko ngā hua kino kāore i te whakakore i tētahi.

Anei te mea e tohu ana ngā hua rerekē o te paturopi:

• Ngā paturopi Anti-Sm: He tino whaihua mō te systemic lupus erythematosus (SLE)
• Ngā paturopi Anti-RNP: E pā ana ki te mate kiko tūhono whakauru
• Ngā paturopi Anti-SSA/Ro: E hono ana ki te mate a Sjögren me te lupus
• Ngā paturopi Anti-SSB/La: I te nuinga o te wā ka kitea i roto i te mate a Sjögren
• Ngā paturopi Anti-Scl-70: E pā ana ki te scleroderma (systemic sclerosis)
• Ngā paturopi Anti-Jo-1: E hono ana ki ngā mate uaua mumura

Kia mōhio mai, ka taea e ētahi tāngata hauora te whai taumata iti o ēnei paturopi me te kore e whakawhanake i tētahi āhua ārai-aunoa. Ka whakaaro tō tākuta ki te pikitia katoa o tō hauora i te wā e whakamārama ana i ēnei hua.

He aha te tikanga o ngā taumata ENA tiketike?

Ko ngā taumata ENA tiketike, pai rānei, e tohu ana kei te whakaputa tō pūnaha ārai mate i ngā paturopi ki ō kiko ake. E whakaatu ana tēnei i te mahi ārai-aunoa, ahakoa kāore i te tika te tikanga kei a koe tētahi mate ārai-aunoa i tēnei wā.

Ko te hiranga o ngā taumata tiketike e whakawhirinaki ana ki ngā paturopi motuhake e piki ana, me te nui o ngā taumata. He nui ake te whaihua o ētahi paturopi ki ētahi āhua i ētahi atu, ā, ko ngā taumata tiketike e pā ana ki te mate kaha ake.

Inā he tiketike ō taumata ENA, ka hiahia pea tō tākuta ki te aroturuki i a koe i te tata atu, ā, ka tūtohu pea i ētahi atu whakamātautau kia mārama ake ai te pikitia o te mea e pā ana ki tō tinana.

He aha ngā āhuatanga tūpono mō ngā taumata ENA kōaro?

He maha ngā āhuatanga ka taea te whakanui i tō tūponotanga ki te whakawhanake i ngā paturopi e kitea ana e ngā whakamātautau ENA. Mā te māramatanga ki ēnei āhuatanga tūpono ka āwhina i a koe me tō tākuta ki te noho mataara ki ngā take ārai-aunoa.

Ko te mea nui e pā ana ki te tūponotanga ko te whai i te hītori o te whānau o ngā mate ā-tinana, nā te mea ka pēnei ngā āhuatanga nei i roto i ngā whānau. Mēnā he lupus, he mate Sjögren, ētahi atu āhuatanga rānei ō ō mātua, ō tēina, ō tuahine, ētahi atu whanaunga tata rānei, tērā pea ka nui ake tō tūponotanga.

Ko ētahi atu mea nui e pā ana ki te tūponotanga ko:

• Ko te wahine (nui ake te pānga o ngā mate ā-tinana ki ngā wāhine)
• Te pakeke i waenga i te 15-45 tau (i te wā e puta tuatahi ana te maha o ngā āhuatanga ā-tinana)
• Ētahi iwi (nui ake ngā reiti i roto i ngā iwi o Awherika-Amerika, Hispanic, me Ahia)
• Te pānga ki ētahi mate ka pā ai te urupare ā-tinana
• Ētahi rongoā ka pā ai te urupare ā-tinana
• Te nui o te pānga ki te rā (ka pā ai te lupus ki ngā tāngata e tūpono ana)
• Ngā taumata nui o te pēhanga, ngā huringa nui rānei o te oranga
• Te kai paipa (ka nui ake te tūponotanga mō ētahi āhuatanga ā-tinana)

Ahakoa te pēnei, he maha ngā tāngata e whai ana i ēnei mea e pā ana ki te tūponotanga kāore rawa i te whakawhanake i ngā mate ā-tinana, i te wā e pēnei ana ētahi atu kāore he mea e pā ana ki te tūponotanga. Ko te whakawhanaketanga o ēnei āhuatanga e pā ana ki ngā pānga uaua i waenga i ngā ira me te taiao.

He aha ngā raruraru ka puta mai i ngā hua ENA pai?

Ko ngā hua ENA pai te tohu i te aroaro o ngā āhuatanga ā-tinana ka pā ki ngā pūnaha okana maha ki te kore e rongoatia. Ko ngā raruraru motuhake e whakawhirinaki ana ki ngā paturopi e noho ana, me te āhuatanga e whakawhanake ana.

Ko te kitenga wawe mā te whakamātautau ENA e āwhina ana ki te ārai i te maha o ngā raruraru mā te tuku i te rongoā wawe. Heoi, he mea nui kia mārama ki te aha ka pā mai mēnā ka haere tonu ēnei āhuatanga me te kore e tika te whakahaere.

Ko ngā raruraru noa e pā ana ki ngā hua ENA pai ko:

• Te kino o ngā hononga me te mate rūmātiki mau tonu e arahi ana ki ngā raruraru haere
• Ngā raruraru tākihi ka piki ki te korenga o te tākihi
• Ngā raruraru o te ngākau tae atu ki te mumura o te uaua o te ngākau
• Te mumura o te pūkahukahu me te kiko e pā ana ki te manawa
• Ngā huringa kiri tae atu ki te kiko me te tairongo
• Te maroke o te kanohi ka arahi ki te kino o te kamo
• Te whai wāhi o te pūnaha io e pā ana ki ngā pākia, ki ngā raruraru rānei o te hinengaro
• Ngā mate toto tae atu ki te anemia me te iti o te tatau o te pūtau toto

Ko te rongo pai ko te mea ka taea e ngā rongoā hou te whakahaere pai i te nuinga o ēnei āhuatanga ina kitea wawe. Mā te aroturuki i ngā wā katoa me te rongoā tika ka āwhina i te aukati, i te whakaiti rānei i ēnei raruraru.

Āhea ahau e kite ai i te tākuta mō ngā hua o te whakamātautau ENA?

Me tino whai i te tākuta ina wātea ana ngā hua o tō ENA, ahakoa he pai, he kino rānei. Me whakamāori e tō tākuta ēnei hua i roto i te horopaki o ō tohu me tō hauora whānui.

Mēnā he pai ō hua, he mea nui kia whakarite wawe i tērā hui. Mā te wawaotanga wawe ka nui te rerekētanga i te whakahaere pai i ngā āhuatanga autoimmune.

Me whakapā atu koe ki tō tākuta i mua i te wā, i muri rānei i te whiwhinga i ō hua mēnā ka pā ki a koe ēnei tohu:

• Te tīmatanga ohorere o te mamae nui o ngā hononga, te pūhi rānei
• Ngā pūhi kiri hou, e kino haere ana rānei, ina koa ki ngā wāhi e pā ana ki te rā
• Te kirika mau tonu kāore he take mārama
• Ngā huringa nui i te mimi, i te toto rānei i roto i te mimi
• Te ngenge nui e pā ana ki ngā mahi o ia rā
• Te uaua ki te manawa, te mamae rānei o te uma
• Ngā kanohi maroke nui, te waha rānei e pā ana ki te kai, ki te kōrero rānei
• Te ngoikore o te uaua e kino haere ana

Kia mahara, kāore he take e mataku ana ki te whai hua ENA pai. He maha ngā tāngata e whai ana i ēnei paturopi e ora ana i ngā oranga noa, hauora hoki me te manaaki hauora tika me te aroturuki.

Ngā Pātai e Pānuia ana mō te Whakamātautau ENA

Q1. He pai te whakamātautau ENA mō te tātai i te lupus?

Āe, he tino whai hua te whakamātautau ENA mō te tātai i te lupus, inā te mea ka taea e ia te kite i ngā paturopi Anti-Sm, he tino motuhake ki te systemic lupus erythematosus. Ki te kitea ngā paturopi Anti-Sm, e whakaatu ana i te lupus, kaua ki ētahi atu āhuatanga autoimmune.

Ka kitea hoki e te whakamātautau ngā paturopi Anti-SSA/Ro, e kitea ana i roto i te 30-40% o ngā tāngata e whai ana i te lupus. Heoi anō, kāore ngā tākuta e whakawhirinaki ana ki te whakamātautau ENA anake mō te tātai i te lupus – ka whakamahi rātou i te taha o ō tohu, te whakamātau tinana, me ētahi atu whakamātautau toto hei hanga i tētahi tātai whānui.

Q2. E kī ana te whakamātautau ENA pai kei te whai au i te mate autoimmune?

Kāore pea. Ahakoa e whakaatu ana ngā hua ENA pai i te mahi autoimmune, ka taea e ētahi tāngata hauora te whai i ngā taumata iti o ēnei paturopi me te kore e whakawhanake i te mate autoimmune. Ka whakaaro tō tākuta i ō tohu, ngā kitenga whakamātau tinana, me ētahi atu hua whakamātautau hei whakatau mēnā kei te whai koe i tētahi āhuatanga autoimmune.

Whakaarohia ngā hua ENA pai hei haki whero e tika ana kia āta aroturukihia, kaua ki te tātai tino. Ka tūtohu pea tō tākuta i te whakamātautau anō, i te aroturuki atu rānei kia kite mēnā ka huri ngā taumata paturopi i te wā.

Q3. Ka taea te huri ngā hua whakamātautau ENA i te wā?

Āe, ka taea te huri ngā hua whakamātautau ENA i te wā. Ka taea te rere kē ngā taumata paturopi i runga i te mahi mate, te urupare ki te rongoā, me ētahi atu āhuatanga. Ka whakamātau pea ētahi tāngata i te kino i te tīmatanga engari ka whakawhanake i ngā hua pai i muri mai i te haere tonu o tō rātou āhuatanga.

Koinei te take e taunaki ana nga taakuta i etahi wa kia tukurua te whakamatautau, ina koa ka huri o tohu, ki te mea ranei i whakamatautauria koe i te tuatahi engari kei te mau tonu o tohu e awangawanga ana. Ma te aroturuki i nga wa katoa e awhina ana ki te whai i te ahua o to mate e urupare ana ki te maimoatanga.

Q4. He rongoa ano ka pa ki nga hua whakamatautau ENA?

Ko etahi rongoa ka pa ki nga hua whakamatautau ENA, ahakoa he mea noa tenei. Ko etahi rongoa e whakamahia ana hei rongoa i te toto tiketike, nga mate ngakau, nga hopu ranei ka puta i etahi wa te whanaketanga o nga paturopi autoimmune.

Ko nga rongoa immunosuppressive e whakamahia ana hei rongoa i nga ahuatanga autoimmune ka whakaheke i nga taumata paturopi i te wa. Me whakamohio tonu ki to taakuta mo nga rongoa me nga taapiri katoa e inu ana koe, na te mea ka awhina tenei korero ki a ratou ki te whakamaori tika i o hua.

Q5. Kia pehea te auau o te whakamatautau ENA?

Ko te auau o te whakamatautau ENA ka whakawhirinaki ki to ahuatanga takitahi. Mena he mate autoimmune kua kitea koe, ka taea e to taakuta te whakamatautau ano i ia wa ki te aroturuki i te mahi mate me te urupare maimoatanga, i te nuinga o te wa ia 6-12 marama.

Mena i kino to whakamatautau tuatahi engari kei te mau tonu o tohu e tohu ana i te mate autoimmune, ka taea e to taakuta te taunaki kia whakamatautauria ano i roto i nga marama 6-12. Mo nga tangata he ahuatanga autoimmune pumau, pai te whakahaere, ka nui pea te whakamatautau iti ake.