Ni iki Benzgalantamine: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zayo n'ibindi

Benzgalantamine ni umuti uvanga galantamine na benzyl alcohol, ugamije gufasha abantu bafite uburwayi bwo mu mutwe na Alzheimer gukomeza ubushobozi bwabo bwo kumenya igihe kirekire. Uyu muti unyobwa mu kanwa ukora ushyigikira imiti yo mu bwonko y'ingenzi mu kwibuka no gutekereza.

Niba wowe cyangwa uwo ukunda warandikiwe benzgalantamine, birashoboka ko ushaka amakuru asobanutse kandi yizewe yerekeye uburyo ikora n'icyo wakwitega. Gusobanukirwa umuti wawe birashobora kugufasha kumva ufite icyizere cyinshi ku rugendo rw'ubuvuzi ruri imbere.

Ni iki Benzgalantamine?

Benzgalantamine ni umuti wandikirwa ugwa mu cyiciro cy'imiti yitwa cholinesterase inhibitors. Yateguwe by'umwihariko kugirango itinde gusenyuka kwa acetylcholine, umuti wo mu bwonko w'ingenzi mu kwibuka, kwiga, n'ibindi bikorwa byo kumenya.

Uyu muti uvanga galantamine hydrobromide na benzyl alcohol nk'umuti ubungabunga. Uku guhuza bifasha kumenya neza ko umuti uguma uhamye kandi ukora neza mugihe ukorera neza sisitemu yawe yo mu gifu.

Muri rusange uzasanga benzgalantamine iboneka nk'umuti unyobwa mu kanwa cyangwa tablet, bigatuma byoroha kubaganga kubaha abarwayi bashobora kugira ingorane zo kumira ibinini.

Benzgalantamine ikoreshwa kubera iki?

Benzgalantamine ikoreshwa cyane cyane mu kuvura uburwayi bwo mu mutwe bworoshye kugeza buringaniye bufitanye isano na Alzheimer. Bifasha gutinda iterambere ry'ibimenyetso nk'ukwibagirwa, urujijo, n'ingorane mu bikorwa bya buri munsi.

Muganga wawe ashobora kugusaba uyu muti niba urimo guhura n'ibimenyetso byo gutangira kugabanuka k'ubushobozi bwo kumenya, nk'ukwibagirwa ibiganiro bya vuba, kugira ingorane zo kubona amagambo, cyangwa guhangana n'imirimo isanzwe. Intego si ukurinda Alzheimer, ahubwo ni ugufasha gukomeza urwego rwawe rwa none rwo gukora igihe kirekire gishoboka.

Rimwe na rimwe, abaganga bashobora kwandikira benzgalantamine kubandi bafite ubumuga bwo mu mutwe, nubwo indwara ya Alzheimer ikomeza kuba yo ikoreshwa cyane. Umuganga wawe azemeza niba uyu muti ukwiriye kubera uko ubuzima bwawe bumeze.

Benzgalantamine ikora ite?

Benzgalantamine ikora ibuza enzyme yitwa acetylcholinesterase, isanzwe isenya acetylcholine mu bwonko bwawe. Mu kwirinda uku gusenya, uyu muti ufasha gukomeza urwego rwo hejuru rw'uyu muti w'ingenzi mu bwonko.

Tekereza acetylcholine nk'intumwa ifasha selile zo mu bwonko kuvugana. Mu ndwara ya Alzheimer, izi ntumwa ziragabanuka, bigatuma ubwonko bwawe bugorwa no gukora ibyibuko bishya no kwibuka ibiriho.

Uyu muti ufatwa nk'ukomeye ku rugero ruciriritse mu kuvura ubumuga bwo mu mutwe. Nubwo utashobora guhagarika indwara ngo itere imbere, ushobora gufasha kugabanya imikorere y'ubwonko kandi ukagufasha kuguma wigenga igihe kirekire kurusha uko byari kugenda utawufata.

Nkwiriye gufata benzgalantamine nte?

Fata benzgalantamine nk'uko umuganga wawe abikwandikiye, akenshi kabiri ku munsi hamwe n'ifunguro ryawe rya mu gitondo n'irya nimugoroba. Kuwufata hamwe n'ibiryo bifasha kugabanya ibibazo byo mu nda kandi bigatuma umubiri wawe wumva neza uyu muti.

Niba ufata umuti unyobwa, koresha igikoresho gipima kiri kumwe n'umuti wawe kugirango wemeze ko upima neza. Ntukoreshe ikiyiko cyo mu rugo, kuko ibi bishobora gutuma ufata doze zitari zo zishobora kugira akamaro gake cyangwa zigatera ingaruka nyinshi.

Gerageza gufata doze zawe ku gihe kimwe buri munsi kugirango ugumane urwego ruzigama mu mubiri wawe. Abantu benshi basanga bifasha guhuza igihe cyo gufata imiti n'ibikorwa bisanzwe nk'ifunguro rya mugitondo n'irya nimugoroba.

Mimina ibinini byose hamwe n'ikirahure cy'amazi. Ntuzabice, uzahate cyangwa uzimenagure keretse umuganga wawe akubwiye kubikora, kuko ibi bishobora kugira ingaruka ku buryo umuti usohoka mu mubiri wawe.

Nkwiriye gufata benzgalantamine igihe kingana iki?

Benzgalantamine ikunze kuba imiti ifatwa igihe kirekire uzakomeza gufata igihe cyose igifitiye akamaro kandi uyihanganira neza. Abantu benshi bayifata amezi cyangwa imyaka, bitewe n'uko uburwayi bwabo bugenda butera imbere.

Muganga wawe azajya asuzuma buri gihe uko witwara ku muti, akenshi buri mezi atatu cyangwa atandatu. Bazareba niba ibimenyetso byo mu mutwe bihagaze, bigenda birushaho, cyangwa bikomeza kugabanuka nubwo uvurwa.

Ni ngombwa kumva ko uyu muti ukora neza iyo ufashwe buri gihe. Guhagarika ako kanya bishobora gutuma imikorere yo mu mutwe igabanuka vuba, bityo impinduka zose kuri gahunda yawe yo kuvurwa zigomba kujyanwa imbere na muganga wawe.

Ni Ibihe Bikorwa Bigaragara Byatewe na Benzgalantamine?

Kimwe n'indi miti yose, benzgalantamine ishobora gutera ibikorwa bigaragara, nubwo abantu benshi bayihanganira neza. Kumva icyo witegura bishobora kugufasha kwitegura neza kandi ukamenya igihe cyo kuvugana na muganga wawe.

Ibikorwa bigaragara cyane ushobora guhura nabyo akenshi biba byoroheje kandi akenshi biragenda bikosoka uko umubiri wawe wimenyereza umuti:

• Kuruka cyangwa kuribwa mu nda
• Kuruka cyangwa kubura ubushake bwo kurya
• Impiswi cyangwa kuribwa mu nda
• Urugero cyangwa kubabara umutwe
• Kugira umunaniro cyangwa intege nke
• Kugabanya ibiro

Ibi bimenyetso byo mu gifu akenshi biba by'igihe gito kandi bishobora kugabanuka iyo ufashe umuti hamwe n'ibiryo kandi ukatangira n'urugero ruto muganga wawe azagenda yongera buhoro buhoro.

Abantu bamwe bashobora guhura n'ibikorwa bigaragara bikomeye bisaba ubufasha bwihuse bwa muganga. Nubwo ibi bidakunze kubaho, ni ngombwa kubimenya:

• Kuribwa mu nda cyane cyangwa kuruka bidahagarara
• Ibimenyetso byo kumuka amazi biturutse ku mpiswi cyangwa kuruka
• Umutima utera gahoro cyangwa utajegajega
• Kubura umwuka cyangwa kuribwa mu gituza
• Urugero rukabije cyangwa guta ubwenge
• Intege nke mu mikaya cyangwa guhinda umushyitsi

Niba wumva ibimenyetso bikomeye nk'ibi, vugana n'umuganga wawe ako kanya cyangwa ushake ubufasha bw'ubuvuzi bwihutirwa niba ibimenyetso bikomeye.

Ninde Utagomba Gufata Benzgalantamine?

Benzgalantamine ntibereye buri wese, kandi umuganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kukwandikira. Indwara zimwe na zimwe zirashobora gutuma uyu muti utaba mwiza cyangwa utagira akamaro kuri wowe.

Ntugomba gufata benzgalantamine niba ufite indwara ikomeye y'impyiko cyangwa umwijima, kuko umubiri wawe ushobora kutabasha gutunganya neza uwo muti. Abantu bafite indwara zimwe na zimwe z'umutima, cyane cyane umuvuduko muto w'umutima cyangwa guhagarara gukomeye k'umutima, bagomba kandi kwirinda uyu muti.

Niba ufite amateka y'ibibazo byo mu gifu, asima, cyangwa ibibazo byo gufatwa, umuganga wawe azakenera gupima neza inyungu n'ibibazo. Izi ndwara zirashobora kwiyongera na benzgalantamine, bityo gukurikiranwa by'umwihariko bishobora kuba ngombwa.

Buri gihe bwire umuganga wawe ku miti yose urimo gufata, harimo imiti igurishwa itagomba kwandikwa na muganga n'ibyongerera imbaraga. Imiti imwe na imwe irashobora gukorana na benzgalantamine, bishobora gutera ingaruka ziteje akaga cyangwa kugabanya imikorere yayo.

Amazina y'ubwoko bwa Benzgalantamine

Benzgalantamine iboneka mu mazina menshi y'ubwoko, Razadyne ikaba ari yo ikoreshwa cyane muri Leta Zunze Ubumwe z'Amerika. Urashobora kandi kubona igurishwa nka Razadyne ER kubera imiti ifatwa igihe kirekire.

Ubwoko bwa galantamine hydrobromide na bwo buraboneka, bukaba burimo ibintu bimwe bikora ariko bishobora kuba bihendutse. Umufarumasiti wawe ashobora kugufasha gusobanukirwa niba urimo guhabwa izina ry'ubwoko cyangwa ubwoko rusange.

Tutitaye ku izina ry'ubwoko cyangwa ubwoko rusange urimo guhabwa, uwo muti ugomba gukora kimwe. Ariko, buri gihe reba umufarumasiti wawe niba imiti yawe isa n'itandukanye n'ibisanzwe, kuko ibi bifasha kumenya neza ko urimo guhabwa umuti ukwiye.

Uburyo bwa Benzgalantamine bindi

Niba benzgalantamine itagukwiriye, hari izindi miti nyinshi zishobora gufasha mu gucunga ibimenyetso bya Alzheimer. Muganga wawe ashobora gutekereza gukoresha donepezil (Aricept), rivastigmine (Exelon), cyangwa memantine (Namenda) nk'izindi nzira.

Buri muti muri iyi ikora mu buryo butandukanye gato kandi ushobora gukwira neza ibyo ukeneye cyangwa uko ubuzima bwawe bumeze. Abantu bamwe babona ko umuti umwe ubafitiye akamaro kurusha undi, bityo kubona uwukwiriye rimwe na rimwe bisaba kwihangana no gukorana bya hafi na muganga wawe.

Uburyo butakoresha imiti nabwo bushobora gushyigikira ubuzima bwo mu mutwe, harimo imyitozo ngororamubiri ya buri gihe, kwifatanya n'abandi, n'ibikorwa byo gushishikariza imitekerereze. Ubu buryo bukora neza iyo buhuriye n'imiti ikwiriye aho gukoreshwa nk'ibisimbura.

Ese Benzgalantamine iruta Donepezil?

Bombi benzgalantamine na donepezil ni imiti ikora neza mu kuvura indwara ya Alzheimer, ariko bakora mu buryo butandukanye gato kandi bashobora gukwira abantu batandukanye neza. Nta muti n'umwe uruta undi.

Benzgalantamine ishobora kugira akamaro ku bantu bahanganye n'ibimenyetso by'imyitwarire ya demansiya, kuko rimwe na rimwe ishobora gufasha mu guhangayika cyangwa ubugizi bwa nabi. Ariko, ishobora gutera ibibazo byo mu nda kurusha donepezil, cyane cyane igihe utangiye kuvurwa.

Muganga wawe azatekereza ibimenyetso byawe byihariye, izindi ndwara ufite, n'uko wihanganira ingaruka ziterwa n'imiti mugihe uhitamo hagati yiyi miti. Abantu bamwe bashobora no kungukirwa no kugerageza byombi mu bihe bitandukanye kugirango barebe niba hari ikora neza kuri bo.

Ibikunze Kubazwa Kuri Benzgalantamine

Ese Benzgalantamine irakwiriye ku bantu barwaye indwara z'umutima?

Benzgalantamine ishobora kugira ingaruka ku mikorere y'umutima, bityo abantu bafite indwara z'umutima runaka bakeneye kwitonda cyane. Muganga wawe ashobora gushaka gukurikirana umutima wawe cyane niba ufite amateka y'ibibazo by'umutima.

Niba ufite umuvuduko w'umutima muto, umutima wazibye, cyangwa izindi ndwara zikomeye z'umutima, muganga wawe ashobora guhitamo umuti utandukanye cyangwa akagutangiza urugero ruto cyane hamwe no kugenzura neza. Ntukigere wibwira ko bidatekanye utabanje kubiganiraho n'umuganga wawe.

Nkwiriye gukora iki niba nanyweye benzgalantamine nyinshi ku buryo butunguranye?

Niba unyweye benzgalantamine nyinshi ku buryo butunguranye kuruta uko byategetswe, vugana n'umuganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya. Kunywa nyinshi bishobora gutera ingaruka zikomeye zirimo isesemi ikabije, kuruka, umuvuduko w'umutima muto, no kunanuka kw'imitsi.

Ntugategereze ngo urebe niba ibimenyetso bigaragara - shakisha ubufasha bw'ubuvuzi ako kanya. Bika urupapuro rw'umuti hamwe nawe kugirango abaganga babone neza icyo wanyoye n'ingano yacyo.

Nkwiriye gukora iki niba nciwe urugero rwa benzgalantamine?

Niba waciwe urugero rwa benzgalantamine, unywe ako kanya wibuka, igihe cyose bitari hafi y'igihe cyo kunywa urugero rwawe rukurikira. Niba hafi y'urugero rwawe rukurikira, reka urugero waciwe ukomeze gahunda yawe isanzwe.

Ntukigere unywa urugero ebyiri icyarimwe kugirango wuzuze urugero waciwe, kuko ibi bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti. Niba ukunda kwibagirwa urugero, tekereza gukoresha igikoresho gitegura imiti cyangwa gushyiraho ibyibutso kuri terefone kugirango bigufashe kuguma ku murongo.

Nshobora kureka kunywa benzgalantamine ryari?

Ugomba kureka kunywa benzgalantamine gusa ukurikije ubuyobozi bw'umuganga wawe. Guhagarika ako kanya bishobora gutera kugabanuka vuba mu mikorere y'ubwenge, bityo icyemezo icyo aricyo cyose cyo guhagarika kigomba gufatwa neza hamwe n'ubuyobozi bw'abaganga.

Muganga wawe ashobora kugusaba guhagarika niba urimo guhura n'ingaruka zitihanganirwa, niba umuti utagifite akamaro, cyangwa niba uburwayi bwawe bwateye imbere kugeza aho izindi nshuti zishobora kuba zikwiriye.

Nshobora kunywa inzoga nkanwa benzgalantamine?

Ni byiza kugabanya cyangwa kwirinda inzoga mugihe ufata benzgalantamine, kuko inzoga zishobora gukomeza ingaruka ziterwa n'umuti kandi zikaba zishobora kubangamira imikorere yawo. Inzoga kandi zishobora kwihutisha imikorere mibi y'ubwonko kubantu bafite uburwayi bwo mu mutwe.

Niba uhisemo kunywa rimwe na rimwe, banza ubiganireho na muganga wawe. Bazagufasha gusobanukirwa icyo gishobora kuba cyiza kuri wowe kandi bazakugenzura niba hari izindi ngaruka zikomeye.