Icyo Methimazole ari cyo: Ibyo ikoreshwa, urugero rwo kuyifata, ingaruka zayo n'ibindi

Methimazole ni umuti wandikirwa na muganga ufasha kugenzura umushyuko w'umubiri, ikibazo cyitwa hyperthyroidism. Tekereza ko umusonga wawe ari ikigo kigenzura imikorere y'umubiri wawe - iyo ukora cyane, methimazole ikora nk'ifurume yoroheje kugirango igabanye ibintu bigere ku rugero ruzima. Uyu muti ubarizwa mu itsinda ryitwa imiti irwanya umusonga, kandi umaze imyaka myinshi ufasha abantu gukemura ibibazo byabo by'umusonga mu buryo butekanye.

Methimazole ni iki?

Methimazole ni umuti ufashwe mu kanwa ubarizwa mu cyiciro cy'imiti yitwa thioamides. Ikora ibyo ikingira umusonga wawe gukora imisemburo myinshi y'umusonga, aricyo gitera ibimenyetso bya hyperthyroidism.

Muganga wawe ashobora kukwandikira methimazole niba umusonga wawe ukora imisemburo myinshi yihutisha imikorere y'umubiri wawe. Ibi bishobora gutuma wumva uhangayitse, bigatuma umutima wawe utera cyane, ugatakaza ibiro, n'ibindi bimenyetso bitari byiza bigira ingaruka ku buzima bwawe bwa buri munsi.

Uyu muti uza mu buryo bw'ibinini kandi ufashwe mu kanwa. Ni uburyo bwo kuvura bugamije gukemura ikibazo cy'umusonga aho gusa guhisha ibimenyetso.

Methimazole ikoreshwa mu iki?

Methimazole ikoreshwa cyane cyane mu kuvura hyperthyroidism, ibaho iyo umusonga wawe ukora imisemburo myinshi y'umusonga. Iki kibazo gishobora gutuma wumva umubiri wawe ukora cyane.

Uyu muti ukunze kwandikirwa indwara ya Graves, aricyo gitera hyperthyroidism cyane. Indwara ya Graves ibaho iyo urwego rwawe rw'ubudahangarwa rukubwira umusonga wawe mu buryo butari bwo gukora cyane, ukora imisemburo myinshi.

Muganga wawe ashobora no kugusaba gukoresha methimazole ku ndwara ya toxic multinodular goiter, aho ibibyimba biri mu ngingo ya thyroïde yawe bikora imisemburo myinshi cyane. Byongeye kandi, irashobora gukoreshwa mu gutegura abarwayi kubagwa thyroïde cyangwa kuvurwa na iodine ya radiyoactive binyuze mu kugenzura urwego rw'imisemburo mbere.

Methimazole ikora ite?

Methimazole ikora ibuza ingingo ya thyroïde yawe gukoresha iodine mu gukora imisemburo ya thyroïde. Ifatwa nk'umuti ukomeye ku rugero ruciriritse ushobora kugenzura neza hyperthyroidism ku bantu benshi.

Uyu muti ubuzwa enzyme yitwa thyroid peroxidase, ingingo ya thyroïde yawe ikeneye kugira ngo ikore imisemburo. Binyuze mu kubuza iyi enzyme, methimazole igabanya umubare w'imisemburo ya thyroïde ingingo yawe ishobora gukora, igarura urwego rwawe mu buryo busanzwe.

Ubu buryo ntibukorwa mu ijoro rimwe - akenshi bifata ibyumweru byinshi kugira ngo ubone ingaruka zose. Umubiri wawe ukeneye igihe cyo gukoresha imisemburo ya thyroïde yarenze urugero yari imaze gukorwa mbere yo kumva umeze neza rwose.

Nkwiriye gufata methimazole nte?

Fata methimazole nk'uko muganga wawe abikwandikiye, akenshi rimwe ku munsi cyangwa igabanyijemo doze ntoya mu gihe cy'umunsi. Urashobora kuyifata hamwe n'ibiryo cyangwa utabifatanije, ariko kuyifata hamwe n'ibiryo bishobora gufasha kwirinda kuribwa mu gifu.

Gerageza gufata umuti wawe ku gihe kimwe buri munsi kugira ngo ugumane urwego ruzigama mu mubiri wawe. Niba uyifata rimwe ku munsi, abantu benshi babona ko bifasha kuyifata hamwe na sausifuri cyangwa ifunguro rya nimugoroba nk'igice cy'akamenyero kabo.

Mimina ibinini byose hamwe n'ikirahure cyuzuye cy'amazi. Ntukavune, utahe cyangwa uteme ibinini keretse muganga wawe akubwiye ko ubikora, kuko ibi bishobora kugira ingaruka ku buryo umuti ukora.

Niba ufata indi miti, yongeraho intera hagati yayo na methimazole igihe bibaye ngombwa. Imiti imwe irashobora guhura na methimazole, bityo buri gihe bwire muganga wawe ibyo ufata byose, harimo n'ibyongerera imbaraga n'imiti itagurishwa ku gasoko.

Nkwiriye kumara igihe kingana iki mfata methimazole?

Ubukure bw'imiti ya methimazole buratandukana cyane ku muntu ku muntu, akenshi bukaba buri hagati y'amezi 12 na 18, nubwo abantu bamwe bashobora kuyikenera igihe kirekire. Muganga wawe azajya akurikirana urugero rw'imisemburo ya thyroïde yawe buri gihe kugirango amenye igihe gikwiye kuri wowe.

Ku ndwara ya Graves, abantu benshi bashobora kureka gufata methimazole nyuma y'umwaka umwe cyangwa 2 niba uburwayi bwabo bugabanutse. Ariko, abantu bamwe bashobora kuyikenera igihe kirekire, n'abandi bashobora kuyifata iteka ryose niba hyperthyroïdie yabo itakira.

Muganga wawe azagabanya buhoro buhoro urugero rwawe aho kuyihagarika ako kanya. Ubu buryo bwo kugabanya bufasha kumenya neza ko urugero rw'imisemburo ya thyroïde yawe ruguma ruhagaze kandi birinda ko ibimenyetso byawe bigaruka vuba cyane.

Ibizami by'amaraso bya buri gihe bizafasha muganga wawe gufata icyemezo cyo kumenya igihe byemewe kugabanya cyangwa guhagarika imiti yawe. Ntukigere uhagarika gufata methimazole ku giti cyawe, kabone niyo wumva umeze neza, kuko ibi bishobora gutuma hyperthyroïdie yawe igaruka.

Ni izihe ngaruka ziterwa na Methimazole?

Kimwe n'imiti yose, methimazole ishobora gutera ingaruka, nubwo abantu benshi bayihanganira neza. Ingaruka nyinshi ziba zoroheje kandi akenshi zigenda zikemuka uko umubiri wawe wimenyereza umuti.

Dore ingaruka zisanzwe ushobora guhura nazo:

• Uruhu rurashira cyangwa kuribwa
• Isesemi cyangwa kuribwa mu nda
• Umutwe
• Urugero
• Kubabara mu ngingo
• Impinduka mu buryohe
• Umusatsi ugenda (akenshi by'agateganyo)

Ibi bimenyetso muri rusange birashobora gucungwa kandi akenshi bigabanuka uko igihe kigenda. Niba bikomeje cyangwa bikugora cyane, ganira na muganga wawe kubyerekeye uburyo bwo kubigabanya.

Hariho kandi ingaruka zimwe na zimwe zitabaho ariko zikomeye zisaba ubufasha bwihutirwa bw'abaganga:

• Ibibazo bikomeye by’umwijima (uruhu cyangwa amaso y'umuhondo, inkari z'umukara, umunaniro ukabije)
• Indwara zikomeye zo mu maraso (gukomereka bidasanzwe, kuva amaraso, indwara zikunze kugaragara, kubabara mu muhogo)
• Urugero rukabije rw'uburwayi (kubura umwuka, kubyimba mu maso cyangwa mu muhogo)
• Urugero rukabije rw'uruhu (uruhu rwakwiriye hose, uruhu rwiruka, umuriro)

Nubwo izi ngaruka zikomeye zitagaragara cyane, ni ngombwa kumenya icyo ugomba kwitaho kandi wahamagara muganga wawe ako kanya niba ubonye kimwe muri ibi bimenyetso.

Ninde utagomba gufata Methimazole?

Methimazole ntikwiriye kuri buri wese, kandi ibintu bimwe na bimwe cyangwa ibihe bituma bitaba byiza gukoresha. Muganga wawe azasuzuma neza amateka yawe y'ubuvuzi mbere yo kwandika uyu muti.

Ntabwo ugomba gufata methimazole niba urwaye allergie cyangwa wigeze kugira urugero rukabije rwarwo mu gihe gishize. Niba waragize ibibazo by’umwijima cyangwa indwara zo mu maraso biturutse kuri methimazole mbere, muganga wawe ashobora guhitamo uburyo bwo kuvura butandukanye.

Gusama bisaba kwitonderwa byihariye hamwe na methimazole. Nubwo bishobora gukoreshwa mugihe cyo gutwita, muri rusange ntabwo ariyo nzira ya mbere, cyane cyane mugihe cyambere cyo gutwita, kubera ibibazo bishobora kuvuka. Muganga wawe azagereranya neza ibyago n'inyungu.

Niba urimo konka, methimazole irashobora kwinjira mu mata, ariko muri rusange bifatwa nkibizewe kurusha imiti yindi ya antithyroid. Muganga wawe azakurikirana wowe n'umwana wawe neza niba ukeneye gukomeza kuvurwa mugihe urera.

Abantu bafite ibibazo by’umwijima cyangwa indwara zo mu maraso bashobora gukenera gukurikiranwa byimazeyo cyangwa uburyo bwo kuvura butandukanye. Buri gihe bwire muganga wawe kubyerekeye indwara iyo ari yo yose ufite mbere yo gutangira methimazole.

Amazina ya Methimazole

Methimazole iboneka munsi yamazina menshi, Tapazole ikaba ariyo isanzwe uhura nayo. Iri zina ryakoreshejwe mumyaka myinshi kandi rizwi neza nabaganga.

Ushobora kandi kubona methimazole igurishwa mu mazina y'ubundi bwoko cyangwa nk'umuti rusange. Methimazole rusange ikora neza nk'ubwoko bw'amazina kandi akenshi iraboneka ku giciro gito.

Uko wakwakira methimazole y'izina ry'ubwoko cyangwa rusange, ibikoresho bikora n'ubushobozi bikomeza kuba kimwe. Umufarimasi wanyu ashobora kubafasha gusobanukirwa ubwoko mwakiriye kandi agasubiza ibibazo byose bijyanye no guhindura hagati yabyo.

Uburyo bwo gusimbuza Methimazole

Niba methimazole itagukwiriye, hariho ubundi buryo bwo kuvura hyperthyroidism. Muganga wawe ashobora kubafasha gushakisha izi nzira zindi zishingiye ku miterere yanyu yihariye n'amateka y'ubuvuzi.

Propylthiouracil (PTU) ni undi muti urwanya thyroid ukora kimwe na methimazole. Akenshi ikundwa mugihe cyo gutwita, cyane cyane mu gihembwe cya mbere, kandi ishobora kuba uburyo niba udashobora kwihanganira methimazole.

Ubuvuzi bwa iodine ya radioactive ni ubundi buryo bwo kuvura bugabanya burundu umusaruro wa hormone ya thyroid. Ubu buvuzi bukubiyemo gufata iodine ya radioactive mu kanwa, ikinjira muri gland yawe ya thyroid kandi buhoro buhoro ikangiza igice cy'umubiri.

Kubaga thyroid (thyroidectomy) birashobora gushyirwaho mu bihe bimwe na bimwe, nk'igihe ufite gland ya thyroid nini cyane cyangwa udashobora gufata imiti irwanya thyroid. Ibi bikubiyemo gukuraho igice cyangwa byose bya gland yawe ya thyroid.

Beta-blockers irashobora gufasha gucunga ibimenyetso nk'umutima utera cyane n'umutwaro mugihe izindi nzira zivura zikora, nubwo zitavura hyperthyroidism y'ibanze ubwayo.

Ese Methimazole iruta Propylthiouracil?

Bombi methimazole na propylthiouracil (PTU) ni imiti irwanya thyroid ikora neza, ariko buri imwe ifite inyungu zayo. Methimazole akenshi ikundwa nk'ubuvuzi bwa mbere kubantu benshi bafite hyperthyroidism.

Methimazole isanzwe ikenera imiti mike ku munsi kurusha PTU, ibyo bikaba byoroshya gukurikiza gahunda yawe yo kuvurwa. Abantu benshi bakeneye gusa gufata methimazole rimwe ku munsi, naho PTU isanzwe ikenera gufatwa inshuro nyinshi umunsi wose.

Ariko, PTU ishobora kuba amahitamo meza mugihe cyo gutwita, cyane cyane mugihembwe cya mbere, kuko ifitanye isano n'ibibazo bike byo kuvuka. PTU nayo ikunda gukoreshwa niba waragize ibibazo by'umwijima hamwe na methimazole mbere.

Muganga wawe azatekereza ibijyanye n'ubuzima bwawe bwite, harimo amateka yawe y'ubuvuzi, niba utwite cyangwa uteganya gutwita, n'uburyo witwara mugihe uvurwa mugihe afata icyemezo cy'umuti ukugirira neza.

Ibikunze Kubazwa Kuri Methimazole

Ese Methimazole iratekanye kubantu barwaye indwara z'umutima?

Methimazole irashobora kuba ingirakamaro kubantu barwaye indwara z'umutima bafite kandi hyperthyroidism. Hyperthyroidism ishyira umutwaro wiyongera kumutima wawe, kandi mugucunga urugero rwa hormone ya thyroïde, methimazole irashobora gufasha kugabanya uyu mutwaro.

Ariko, muganga wawe azagukurikiranira hafi niba ufite indwara y'umutima. Bazashaka kumenya neza ko urugero rwa hormone ya thyroïde yawe isanzwe, imiti yawe y'umutima ikiri kumipimo ikwiriye kuri wowe.

Niba ufite indwara y'umutima, ni ngombwa cyane gufata methimazole nkuko byategetswe kandi ukubahiriza gahunda yose yo gusuzumwa. Muganga wawe ashobora kandi gutegeka beta-blockers kugirango ifashe gucunga ibimenyetso bifitanye isano n'umutima mugihe methimazole itangira gukora.

Nigute nzakora niba mfashwe methimazole nyinshi bitunguranye?

Niba ufata methimazole nyinshi bitunguranye, vugana na muganga wawe cyangwa ikigo gishinzwe gucunga ubumara ako kanya. Gufata nyinshi bishobora gutuma urugero rwa hormone ya thyroïde yawe rugabanuka cyane, bigatuma hypothyroidism.

Ibimenyetso byo kunywa byinshi bishobora kuba umunaniro ukabije, kumva ukonje, kwiheba, cyangwa gutekereza gahoro. Ariko, ibi bimenyetso ntibishobora kugaragara ako kanya, kuko impinduka za hormone ya thyroid zifata igihe kugira ngo zigire ingaruka ku mubiri wawe.

Ntugerageze "kuringaniza" umuti wanywe byinshi wirinda doze zizaza. Ahubwo, shakisha inama z'abaganga ako kanya kandi ukomeze gufata doze zawe zisanzwe nkuko byategetswe keretse muganga wawe akubwiye ibindi.

Nkwiriye gukora iki ninsimbye doze ya Methimazole?

Niba usimbye doze ya methimazole, yifate uko wibuka, keretse igihe cyegereye doze yawe itaha iteganyijwe. Muricyo gihe, simba doze wasimbye hanyuma ufate doze yawe itaha ku gihe gisanzwe.

Ntufate doze ebyiri icyarimwe kugirango wuzuze doze wasimbye, kuko ibi bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti. Niba ukunda kwibagirwa doze, tekereza gushyiraho alarme ya buri munsi cyangwa gukoresha umuteguro w'imiti kugirango ugufashe kwibuka.

Niba usimbuza doze buri gihe, urugero rwa hormone ya thyroid rushobora guhinduka. Ganira na muganga wawe kubijyanye n'uburyo bwo kugufasha kwibuka imiti yawe, kuko gufata imiti buri gihe ni ngombwa kugirango uvure uburwayi bwawe neza.

Nshobora guhagarika ryari gufata Methimazole?

Ugomba guhagarika gufata methimazole gusa mugihe muganga wawe akubwiye ko bifite umutekano kubikora, hashingiwe ku ngaruka z'ibizamini byawe by'amaraso n'igihe umaze uvurwa. Guhagarika kare bishobora gutuma hyperthyroidism yawe isubira.

Muganga wawe azagabanya doze yawe buhoro buhoro aho kuyihagarika ako kanya. Ubu buryo bushobora gufata ibyumweru byinshi cyangwa amezi, muricyo gihe uzakenera ibizamini by'amaraso buri gihe kugirango ukurikirane urugero rwa hormone ya thyroid.

Ndetse na nyuma yo guhagarika methimazole, birashoboka ko uzakenera ibizamini by'amaraso bya buri gihe kugirango wemeze ko hyperthyroidism yawe itagaruka. Abantu bamwe bageraho gukira igihe kirekire, mugihe abandi bashobora gukenera kongera kuvurwa niba ibimenyetso byabo bisubiye.

Nshobora gufata Methimazole hamwe n'indi miti?

Methimazole ishobora gukorana n'imiti imwe n'imwe, bityo ni ngombwa kubwira muganga wawe ibyo urimo ufata byose. Imwe mu miti igabanya amaraso, nka warfarin, ishobora gukenera guhindurwa ku bipimo iyo utangiye gufata methimazole.

Imiti imwe n'imwe ivura ibibazo by'umutima ishobora no gukorana na methimazole. Muganga wawe azakugenzura neza niba ukeneye gufata iyi miti yombi icyarimwe kandi ashobora guhindura ibipimo uko bikwiye.

Buri gihe ujye umenyesha muganga wawe imiti mishya yose, ibyongerera imbaraga, cyangwa imiti igurishwa itagomba uruhushya ushaka gutangira gufata mugihe ufata methimazole. Ibi birimo vitamine, ibyongerera imbaraga bikomoka ku bimera, ndetse n'imiti ivura ibicurane, kuko bimwe bishobora kugira ingaruka ku buryo methimazole ikora mu mubiri wawe.