Penicillamine ni iki: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zayo n'ibindi

Penicillamine ni umuti wandikirwa na muganga ufasha umubiri wawe gukuramo umuringa urenze urugero n'izindi ntungamubiri zifite uburozi, mu gihe kandi utuma ubudahangarwa bw'umubiri butarenga urugero. Ushobora kwandikirwa uyu muti niba ufite indwara ya Wilson, umusonga wo mu ngingo, cyangwa indwara zimwe na zimwe z'ibinyoro zitagaragaje impinduka nziza nyuma yo gukoresha izindi miti.

Uyu muti umaze imyaka myinshi ufasha abantu guhangana n'izi ndwara zikomeye. Nubwo bisaba gukurikiranwa neza, abarwayi benshi babona impinduka zigaragara iyo penicillamine ari yo miti ibakwiriye.

Penicillamine ni iki?

Penicillamine ni umuti wihariye ukora nk'ikintu gifata ibyuma n'ikintu gica intege ubudahangarwa bw'umubiri. Ikintu gifata ibyuma gikora nk'akantu gafata ibintu mu buryo bwa molekile, kigafatana n'ibyuma biri mu mubiri wawe kugira ngo bishobore gukurwamo mu buryo bwizewe binyuze mu nkari zawe.

Nubwo ifite iryo zina, penicillamine ntaho ihuriye na antibiyotike ya penicillin. Izina ryayo ryaturutse ku buryo yamenyekanyeho bwa mbere, ariko iyo miti yombi ikora mu buryo butandukanye rwose mu mubiri wawe.

Uyu muti ubarirwa mu cyiciro cy'imiti yitwa imiti ivura indwara igahindura imikorere y'umubiri (DMARDs) iyo ikoreshwa mu kuvura umusonga wo mu ngingo. Ifatwa nk'umuti wa kabiri, bivuze ko abaganga basanzwe bagerageza izindi nzira mbere yo kwemeza penicillamine.

Penicillamine ikoreshwa mu kuvura iki?

Penicillamine ivura indwara nyinshi zitandukanye, buri imwe ikaba isaba uburyo butandukanye bwo kuyivura no kuyikurikirana. Muganga wawe azakwandikira uyu muti iyo izindi miti itatanze impinduka zihagije cyangwa iyo ufite indwara yihariye ikira neza cyane iyo ukoresheje uyu muti.

Indwara zisanzwe zivurwa na penicillamine zirimo:

• Indwara ya Wilson: Indwara ya gihanga aho umuringa wiyongera mu buryo buteye ubwoba mu mwijima wawe, ubwonko, n'izindi ngingo
• Arthritis ya Rheumatoid: Iyo imiti indi itarashoboye kugenzura kubyimba no kwangirika kw'ingingo
• Cystinuria: Indwara aho amabuye ya cystine akora amabuye mu mpyiko inshuro nyinshi
• Kurohwa n'ibyuma biremereye: By'umwihariko ku muringa, umutovu, cyangwa gukorerwa ku mercure

Mu buryo butavugwa cyane, abaganga bashobora kwandika penicillamine kuri scleroderma, indwara y'imyanya ihuza itera uruhu n'ingingo gukomera. Iyi mikoreshereze isaba kwitonderwa cyane kuko inyungu n'ibibazo bikenera isuzuma ryimbitse.

Penicillamine ikora ite?

Penicillamine ikora hakoreshejwe uburyo bubiri bw'ingenzi bitewe n'indwara urimo kuvura. Ku ndwara zijyanye n'ibyuma nk'indwara ya Wilson, ifatana n'umuringa urenze mu bice byawe by'umubiri kandi ifasha impyiko zawe kuwusohora binyuze mu nkari.

Mugihe uvura arthritis ya rheumatoid, penicillamine ihindura imikorere y'ubudahangarwa bwawe. Igabanya umusaruro wa za antibodi zimwe na zimwe n'ibintu byangiza byibasira ingingo zawe, nubwo uburyo nyabwo butumvikana neza.

Uyu muti ufashwe nk'ukomeye mu rugero ruciriritse hamwe n'ingaruka zikomeye ku ngingo z'umubiri wawe. Ntabwo ari umuti wihuse – mubisanzwe uzakenera kuwufata mu gihe cy'amezi menshi mbere yo kubona inyungu zose, cyane cyane mu kuvura arthritis.

Nkwiriye gufata penicillamine nte?

Gufata penicillamine neza ni ngombwa kugirango bigire akamaro kandi bigire umutekano. Muganga wawe azaguha amabwiriza yihariye ashingiye ku ndwara yawe, ariko hariho amabwiriza rusange akoreshwa kuri buri wese.

Jya ufata penicillamine buri gihe ku gifu cyambaye ubusa, byibuze isaha imwe mbere yo kurya cyangwa amasaha abiri nyuma yo kurya. Ibiryo bigabanya cyane umubare w'imiti umubiri wawe winjiza, bishobora gutuma imiti idakora neza.

Uburyo bwo kunywa imiti yawe neza:

• Mimina ibinini byose hamwe n'ikirahure cyuzuye cy'amazi
• Jya utandukanya doze mu gihe cy'umunsi wose niba ufata imiti inshuro nyinshi ku munsi
• Irinda amata, imiti irwanya aside, ibyongera icyuma, cyangwa ibyongera zinc mu masaha 2 nyuma yo gufata doze yawe
• Fata imiti yawe mu masaha amwe buri munsi kugira ngo ugumane urwego ruzigama

Niba ugira ikibazo cyo kumira ibinini, ganira na farumasiye wawe niba ibikubiye muri byo bishobora kuvangwa n'ibiryo. Ntukigere ufata iki cyemezo wenyine, kuko byagira ingaruka ku buryo umuti ukora.

Nzamara igihe kingana iki mfata Penicillamine?

Igihe cyo kuvura na penicillamine gitandukanye cyane bitewe n'uburwayi bwawe bwihariye n'uburyo wemera imiti. Ku ndwara ya Wilson, ubusanzwe uzakenera kuvurwa ubuzima bwawe bwose kugira ngo wirinde ko umuringa wongera kwiyongera.

Ubuvuzi bwa artrite ya reumatoide ubusanzwe busaba byibuze amezi 6 mbere yo gushobora gusuzuma niba umuti ufasha. Abantu benshi bakomeza kuwufata imyaka myinshi niba ugenzura neza ibimenyetso byabo kandi bakawihanganira neza.

Muganga wawe azasuzuma buri gihe niba ukwiye gukomeza kuvurwa. Bazatekereza ibintu nk'uburyo ibimenyetso byawe bigenzurwa neza, ingaruka zose ubona, n'ibisubizo byo mu bizami by'amaraso bisanzwe n'izindi nzira zo gukurikirana.

Ni izihe ngaruka ziterwa na Penicillamine?

Penicillamine ishobora gutera ingaruka zitandukanye, kuva ku zoroheje kandi zishobora gucungwa kugeza ku ndwara zikomeye zisaba ubuvuzi bwihutirwa. Kumva icyo ugomba kwitondera bifasha kuguma mu mutekano mu gihe ubona inyungu zo kuvurwa.

Ingaruka zisanzwe ushobora guhura nazo zirimo:

• Isesemi no kubura ubushake bwo kurya, cyane cyane mu byumweru bike bya mbere
• Impinduka mu buryohe (uburyohe bw'icyuma cyangwa kubura uburyohe)
• Uruhu ruruka cyangwa kuribwa
• Ibibazo byo mu gihe cyo gukora ibiryo birimo impiswi cyangwa kuribwa mu nda
• Ibibazo byo mu kanwa cyangwa ibisebe

Ingaruka zikomeye zigomba kwitabwaho ako kanya na muganga. Izi zirimo ibimenyetso bikomeye byo ku ruhu, ibimenyetso byo kurwara amaraso nk'imvune idasanzwe cyangwa kuva amaraso, umuriro udashira, cyangwa ibibazo by'impyiko bigaragazwa no guhinduka mu kunyara.

Ibice bimwe na bimwe bidakunze kubaho ariko bikomeye bishobora kwiyongera uko igihe kigenda, harimo indwara ziterwa n'umubiri ubwawo nka syndrome isa na lupus cyangwa indwara z'intege nke z'imitsi. Muganga wawe azagukurikiranira hafi akoresheje ibizamini by'amaraso bya buri gihe kugirango abimenye hakiri kare.

Ninde utagomba gufata Penicillamine?

Abantu bamwe na bamwe bagomba kwirinda penicillamine kubera ibyago byiyongera byo kurwara bikomeye. Muganga wawe azasuzuma neza amateka yawe mbere yo kugusaba uyu muti.

Ntugomba gufata penicillamine niba:

• Wigeze kugira allergie zikomeye kuri penicillamine mu gihe gishize
• Umutwite cyangwa ufite gahunda yo gutwita
• Ufite indwara ikomeye y'impyiko cyangwa kunanirwa kw'impyiko
• Ufite amateka y'indwara z'amaraso nka aplastic anemia
• Ubu uri gukoresha ibiyobyabwenge bya zahabu mu kuvura umusonga

Abantu bafite lupus, myasthenia gravis, cyangwa izindi ndwara ziterwa n'umubiri ubwawo bakeneye kwitabwaho by'umwihariko. Nubwo penicillamine itabujijwe rwose, ibyago n'inyungu bisaba isuzuma ryitondewe cyane.

Niba uri konjesha, ganira n'umuganga wawe ku bindi bisubizo. Inganda ntoya za penicillamine zishobora kwinjira mu mata y'ibere kandi zishobora kugira ingaruka ku mwana wawe.

Amazina ya Penicillamine

Penicillamine iboneka munsi y'amazina menshi y'ubwoko, hamwe na Cuprimine na Depen ariyo miterere isanzwe itangwa muri Leta Zunze Ubumwe. Izi zirimo ibintu bimwe bikora ariko bishobora kugira ibintu bitagira akamaro bitandukanye cyangwa imiterere ya capsule.

Farumasi yawe irashobora gusimbuza hagati y'ubwoko keretse muganga wawe yanditse by'umwihariko "ntagusimbuza" ku byo wanditse. Niba ubonye impinduka zose uko wumva nyuma yo guhindura ubwoko, menyesha muganga wawe ako kanya.

Ubundi bwoko bwa penicillamine buraboneka kandi bukora neza nk'ibicuruzwa by'amazina. Itandukaniro rikuru ni igiciro, nubwo abantu bamwe basanga boroherwa n'uburyo bumwe kurusha ubundi.

Uburyo bwo gusimbuza Penicillamine

Hariho uburyo bwinshi bwo gusimbuza penicillamine, nubwo guhitamo neza biterwa rwose n'uburwayi bwawe bwihariye n'amateka yawe y'ubuvuzi. Muganga wawe azatekereza izi nzira niba penicillamine itagukwiriye cyangwa niba ugize ingaruka zidakwiriye.

Kubera indwara ya Wilson, trientine ni ikindi kintu gishobora gukuraho ibyuma gikora kimwe na penicillamine. Zinc acetate itanga uburyo butandukanye bwo gukumira imitsi ya copper aho gukuraho copper isanzweho.

Arthritis ya rheumatoid ifite uburyo bwinshi bwo kuvura buriho uyu munsi. Methotrexate, sulfasalazine, n'imiti mishya ya biyolojiya akenshi itanga ibisubizo byiza hamwe n'ingaruka nkeya kurusha penicillamine.

Kubera amabuye yo mu mpyisi aterwa na cystinuria, kongera kunywa amazi no guhindura imirire ni uburyo bwa mbere. Niba imiti ikenewe, tiopronin ikora kimwe na penicillamine ariko ishobora gutera ingaruka nkeya.

Ese Penicillamine iruta Methotrexate?

Penicillamine na methotrexate bifite uruhare rutandukanye mu kuvura arthritis ya rheumatoid, bituma kugereranya byoroshye. Methotrexate akenshi ni umuti wa mbere wo guhitamo arthritis ya rheumatoid kuko ifitiye akamaro abantu benshi kandi ifite ingaruka ziteganywa.

Penicillamine akenshi yagenewe ibihe aho methotrexate n'ubundi buryo bwa mbere bwo kuvura bitagize akamaro. Ntabwo ari byiza cyangwa bibi - ni igikoresho gitandukanye gikora binyuze mu buryo butandukanye mu mubiri wawe.

Gu hitamo hagati y'iyi miti biterwa n'ibintu nk'ubwoko bwawe bwihariye bwa arthritis, izindi ndwara ufite, imiti umaze gufata, n'uburyo witwaye ku miti yabanje.

Umuvuzi wawe w’indwara z’imitsi azagufasha gusobanukirwa umuti utanga uruvange rwiza rwo gukora neza no kugira umutekano mu bihe byawe byihariye.

Ibikunze Kubazwa ku bijyanye na Penicillamine

Ese Penicillamine irakoreshwa neza ku bantu barwaye indwara z’umutima?

Penicillamine muri rusange irashobora gukoreshwa neza ku bantu barwaye indwara z’umutima, ariko bisaba gukurikiranwa neza. Uyu muti ntugira ingaruka ku mutima wawe, ariko zimwe mu ngaruka zidasanzwe nk'indwara ziterwa n'ubwirinzi bw'umubiri zishobora kugira ingaruka ku mikorere y'umutima.

Muganga wawe azashaka kumenya ibijyanye n'indwara z'umutima mbere yo kugusaba penicillamine. Bashobora kugusaba kujya kwa muganga kenshi cyangwa ibizamini byihariye kugira ngo barebe ko ubuzima bw'umutima wawe bukomeza kuba bwiza mu gihe uvurwa.

Nkwiriye gukora iki niba nanyoye penicillamine nyinshi bitunguranye?

Niba unyoye penicillamine nyinshi kuruta uko byategetswe, vugana na muganga wawe cyangwa ikigo gishinzwe kurwanya ubumara ako kanya. Ntukegere ngo urebe niba ugira ibimenyetso, kuko gufata ingamba hakiri kare buri gihe ni byiza.

Mu gihe utegereje inama ya muganga, ntugerageze kwivugisha ngo uruke keretse niba wabitegetswe. Bika urupapuro rw'umuti hamwe nawe kugira ngo abaganga babone neza icyo wanyoye n'ingano yacyo.

Ibimenyetso byo kunywa umuti mwinshi bishobora kuba isesemi ikabije, kuruka, urujijo, cyangwa kuva amaraso bidasanzwe. Ariko, n'iyo wumva umeze neza, isuzuma rya muganga riracyakenerwa nyuma yo kunywa umuti mwinshi.

Nkwiriye gukora iki niba nirengagije doze ya penicillamine?

Niba wibagiwe gufata doze ya penicillamine, yifate vuba na bwangu wibuka, ariko niba hashize amasaha atarenze 4 uhereye igihe cyari giteganyijwe. Niba byarenzeho, reka doze wibagiwe hanyuma ufate doze yawe iteganyijwe igihe gisanzwe.

Ntuzigere ufata doze ebyiri icyarimwe kugira ngo usimbure doze wibagiwe. Ibi bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti utagize inyungu zinyongera.

Niba ukunda kwibagirwa imiti, gerageza gushyiraho alarme kuri telefone yawe cyangwa ukoreshe agasanduku kabugenewe. Gufata imiti buri gihe ni ngombwa kugira ngo penicillamine ikore neza kandi itagize ingaruka.

Ni ryari nshobora kureka gufata Penicillamine?

Ntuzigere uhagarika gufata penicillamine ako kanya utabanje kubiganiraho na muganga wawe. Ku ndwara ya Wilson, guhagarika imiti bishobora gutuma umuringa wiyongera vuba, bikaba byateza ibibazo bikomeye.

Ku bantu barwaye umusonga, muganga wawe ashobora kugabanya buhoro buhoro urugero rw'umuti ufata niba uburwayi bwawe bumaze igihe kirekire butajegajega. Iyi nzira, yitwa tapering, ifasha kwirinda ko umusonga wongera kwibasira umubiri mu gihe hamenyekana niba ugikeneye uwo muti.

Muganga wawe azatekereza ku bintu nk'igihe umaze ufata penicillamine, uko ifasha kugenzura uburwayi bwawe, niba hari ingaruka zikomeje kuba ikibazo. Icyemezo nk'iki kigomba gufatirwa hamwe n'ikipe yawe y'ubuvuzi.

Nshobora kunywa inzoga niba mfata Penicillamine?

Gukoresha inzoga mu rugero ruto muri rusange birakwiriye mugihe ufata penicillamine, ariko ni byiza kubiganiraho na muganga wawe. Inzoga ntigira icyo itwara penicillamine, ariko zombi zishobora kugira ingaruka ku mwijima wawe n'impyiko.

Niba urwaye indwara ya Wilson, umwijima wawe ushobora kuba warangiritse kubera umuringa, bigatuma wumva cyane ingaruka z'inzoga. Muganga wawe ashobora kugusaba kugabanya cyangwa kwirinda inzoga rwose muri iyi situation.

Ku kuvura umusonga, kunywa inzoga rimwe na rimwe mu muryango birakwiriye, ariko kunywa inzoga nyinshi bishobora kubuza umubiri wawe gukora neza uwo muti.