Rivastigmine ni iki: Ibikoresho, Uburyo bwo gufata, Ingaruka ziterwa n'ibindi

Rivastigmine ni umuti wandikirwa na muganga ufasha kugabanya gutakaza urwibutso n'ibibazo byo gutekereza ku bantu barwaye indwara ya Alzheimer na demansiya. Uyu muti ubarirwa mu itsinda ry'imiti yitwa cholinesterase inhibitors, ikora mugihe ikomeza imisemburo imwe yo mu bwonko ikora igihe kirekire kugirango ishyigikire urwibutso n'ubushobozi bwo gutekereza.

Nubwo rivastigmine idashobora kuvura izi ndwara, irashobora gufasha wowe cyangwa uwo ukunda gukora ibikorwa bya buri munsi no gukomeza ubwenge igihe kirekire. Tekereza nk'aho uha sisitemu y'ubwonko bwawe imbaraga zoroheje mugihe ikeneye ubufasha bwihariye.

Rivastigmine ni iki?

Rivastigmine ni umuti w'ubwonko ufasha kubungabunga urwibutso n'ubushobozi bwo gutekereza ku bantu barwaye demansiya. Iza mu buryo bwa capsule, umuti unyobwa, na plasters zishyirwa ku ruhu ushobora gukoresha murugo ukurikiza ubuyobozi bwa muganga wawe.

Uyu muti ufatwa nk'ubuvuzi bufite imbaraga ziringaniye kubijyanye no kugabanuka k'ubushobozi bwo kumenya. Ntabwo ari woroshye nk'ibindi byongerera imbaraga, ariko kandi ntabwo ari nk'ubuvuzi bushya bwo gukoresha. Abantu benshi babona ko bishoboka nk'igice cy'ibikorwa byabo bya burimunsi.

Uyu muti ukora mugihe ubuza enzyme isenya acetylcholine, umusemburo wo mu bwonko w'ingenzi mu rwibutso no kwiga. Mugukomeza uyu musemburo urahari, rivastigmine ifasha selile z'ubwonko kuvugana neza.

Rivastigmine ikoreshwa kubera iki?

Rivastigmine ivura demansiya yoroheje kugeza hagati iterwa n'indwara ya Alzheimer na Parkinson. Muganga wawe arayikwandikira mugihe ufite ibibazo byo kwibuka, urujijo, cyangwa ingorane mukora imirimo ya buri munsi igira ingaruka kumitwe yawe.

Uyu muti ufasha ibimenyetso byinshi byo kumenya bishobora kuba biteye impungenge cyane kuri wowe n'umuryango wawe. Ibi nibyo rivastigmine ishobora gufasha kunoza:

• Ibibazo byo kwibuka no kwibagirwa
• Kugorana kwibanda cyangwa gutega amatwi
• Kutamenya igihe, ahantu, cyangwa abantu bazwi
• Kugorana gukemura ibibazo no gufata ibyemezo
• Ingorane z'ururimi n'itumanaho
• Kugorana gucunga imirimo ya buri munsi nko guteka cyangwa gucunga amafaranga

Ni ngombwa gusobanukirwa ko rivastigmine ifasha gucunga ibimenyetso aho gukiza indwara yihishe. Abantu benshi basanga bibafasha gukomeza ubwigenge bwabo n'ubwenge bwabo igihe kirekire.

Rivastigmine ikora ite?

Rivastigmine ikora irinda imisemburo yo mu bwonko yitwa acetylcholine ikenewe cyane mu kwibuka no gutekereza. Muri dementia, enzyme yitwa acetylcholinesterase isenya uyu musemburo vuba cyane, bigatuma habaho ibibazo by'itumanaho hagati y'uturemangingo tw'ubwonko.

Uyu muti ubuza iyi enzyme, ukemerera acetylcholine gukomeza gukora igihe kirekire mu bwonko bwawe. Ibi bituma uturemangingo tw'ubwonko bwawe tugira igihe kinini cyo kohereza no kwakira ubutumwa bw'ingenzi bufasha mu kwibuka, kwitondera, no gutekereza.

Nk'umuti ufite imbaraga ziringaniye, rivastigmine itanga ubufasha bw'ingirakamaro itabayeho cyane. Abantu benshi babona impinduka zitinda mu mikorere yabo ya buri munsi mu byumweru bike cyangwa amezi make nyuma yo gutangira kuvurwa.

Nkwiriye gufata rivastigmine nte?

Fata rivastigmine nk'uko umuganga wawe abitegeka, akenshi kabiri ku munsi hamwe n'ifunguro kugira ngo ugabanye kuribwa mu gifu. Ibinini n'umuti wo kunywa bikwiye gufatwa mu gitondo na nimugoroba, naho ibishishwa bishyirwa rimwe ku munsi ku ruhu rumeze neza kandi rwashye.

Uku niko wafata rivastigmine mu buryo bwizewe kandi neza:

• Fata ibinini cyangwa amazi hamwe n'ibiryo kugira ngo wirinde isesemi no kuribwa mu nda
• Minya ibinini byose hamwe n'amazi - ntukabikore, ntukabumire, cyangwa ubifungure
• Vanga umuti wo kunywa n'amazi, umutobe, cyangwa soda niba bikenewe
• Shyira ibishishwa ahantu nk'umugongo wo hejuru, igituza, cyangwa ukuboko kwo hejuru
• Hindura ahantu ushyira ibishishwa buri munsi kugira ngo wirinde kuribwa kw'uruhu
• Kura igishishwa gishaje mbere yo gushyiraho gishya

Muganga wawe ashobora gutangira kugutera urugero ruto buhoro buhoro akaruzamura mu byumweru byinshi. Ubu buryo bufasha umubiri wawe kumenyera umuti kandi bugabanya amahirwe yo kugira ingaruka ziterwa nawo.

Nzamara Igihe Kingana Iki Ndafashe Rivastigmine?

Ubusanzwe uzajya ufata rivastigmine igihe cyose ikomeje kugufasha ku bimenyetso byawe kandi muganga wawe abikugiriye inama. Abantu benshi bakoresha uyu muti amezi menshi kugeza ku myaka myinshi nk'igice cy'umugambi wabo wo gucunga indwara yo gutakaza ubwenge igihe kirekire.

Muganga wawe azajya akurikirana uko urimo utera imbere buri gihe binyuze mu gusuzumwa kandi ashobora guhindura uburyo uvurwa bitewe n'uko urimo witwara. Abantu bamwe bungukirwa na rivastigmine imyaka myinshi, mu gihe abandi bashobora gukenera guhindura imiti itandukanye uko igihe kigenda.

Ni ngombwa kutareka rivastigmine mu buryo butunguranye utabanje kuvugana na muganga wawe. Guhagarara mu buryo butunguranye bishobora gutuma ibimenyetso byawe birushaho kwiyongera vuba, bityo impinduka zose ku buryo uvurwa zigomba gukorwa buhoro buhoro hakurikijwe ubuyobozi bwa muganga.

Ni Izihe Ngaruka Ziterwa na Rivastigmine?

Rivastigmine ishobora gutera ingaruka ziterwa na yo, nubwo abantu benshi bayihanganira neza iyo itangiye buhoro buhoro. Ingaruka zikunze kugaragara zireba sisitemu yawe yo mu gifu kandi akenshi zirushaho gukira uko umubiri wawe umenyera umuti.

Kumva icyo witegura bishobora kugufasha kumva witeguye kandi ukamenya igihe cyo kuvugana n'umuganga wawe. Hano hari ingaruka zikunze kugaragara:

• Uburwayi bwo kuruka no kuribwa
• Kubura ubushake bwo kurya no kugabanya ibiro
• Impiswi cyangwa kuribwa mu nda
• Isesemi cyangwa kumva utameze neza
• Umutwe
• Umunaniro cyangwa intege nke
• Umuriro cyangwa guhinda umushyitsi

Ibi bimenyetso akenshi bigabanuka mu byumweru bike umubiri wawe umaze kubimenyera. Gufata umuti hamwe n'ibiryo no gutangira n'urugero ruto birashobora gufasha kugabanya ibi byose.

Abantu bamwe bahura n'ingaruka zidakunze kugaragara ariko zikomeye zisaba ubufasha bwihutirwa. Nubwo bidasanzwe, ni ngombwa kubimenya:

• Kuruka bikabije bitahagarara
• Ibimenyetso byo kumuka amazi biturutse ku mpiswi zihoraho
• Impinduka zidasanzwe mu mutima
• Isesemi ikabije cyangwa kugwa igihumure
• Kugorana kwihagarika
• Uburwayi bwo gufatwa (bidasanzwe cyane)

Niba uhuye n'ikimenyetso kimwe muri ibi bikomeye, vugana n'umuganga wawe ako kanya cyangwa usabe ubufasha bwihutirwa. Abantu benshi basanga inyungu za rivastigmine zirenze ibibazo by'igihe gito by'ingaruka zoroheje.

Ninde utagomba gufata Rivastigmine?

Rivastigmine ntabwo ikwiriye kuri buri wese, kandi umuganga wawe azasuzuma neza amateka yawe mbere yo kuyandika. Indwara zimwe na zimwe zirashobora gutuma uyu muti utaba mwiza cyangwa utagira akamaro kuri wewe.

Umuganga wawe azashaka kumenya ibijyanye n'indwara zihari zishobora kugira ingaruka ku buryo witwara kuri rivastigmine. Aha hari ibihe uyu muti utakwiriye:

• Kumenya allergie kuri rivastigmine cyangwa imiti isa nayo
• Indwara ikabije y'umwijima cyangwa impyiko
• Ibibazo byo mu nda bikomeye cyangwa indwara zituma amaraso ava
• Asima ikabije cyangwa ibibazo byo guhumeka
• Uburwayi bumwe na bumwe bwo mu mutima
• Kubangamirwa kw'inkari cyangwa ibibazo bikomeye by'umuvure
• Epilepsi cyangwa uburwayi bwo gufatwa

Byongeye kandi, abantu bamwe bakeneye gukurikiranwa cyane cyangwa guhindurirwa urugero rwa rivastigmine. Umuganga wawe azatekereza kuri ibi bintu neza:

• Gusama inda cyangwa konsa
• Amateka y'ibibazo by'umutima
• Uburemere buke cyangwa imirire mibi
• Gufata izindi miti igira ingaruka ku mikorere y'ubwonko
• Kubagwa vuba cyangwa kurwara

Ntugacike intege niba rivastigmine itagukwiriye. Hariho ubundi buryo bwo kuvura buriho, kandi muganga wawe azakorana nawe kugirango abone uburyo bwiza bujyanye n'icyo urwaye.

Amazina y'ubwoko bwa Rivastigmine

Rivastigmine iboneka ku izina ry'ubwoko bwa Exelon, iboneka mu buryo bwa capsule, umuti unyobwa, na patch zishyirwa ku ruhu. Ubwoko bwa rivastigmine bwa generic buraboneka kandi bukora neza nk'umuti w'izina ry'ubwoko.

Farumasi yawe ishobora kugira ubwoko butandukanye bwa rivastigmine ya generic. Ubwoko bwose bwemewe na FDA burimo ibintu bikora kimwe kandi byujuje ubuziranenge bumwe, bityo ushobora kugira icyizere ku mikorere yabyo.

Niba uhindura hagati y'ubwoko bw'izina ry'ubwoko na generic, cyangwa hagati y'abakora generic batandukanye, bimenyeshe muganga wawe. Nubwo imiti ihwanye, abantu bamwe babona itandukaniro rito mu buryo bumva cyangwa basubiza.

Uburyo bwa Rivastigmine

Imiti myinshi ishobora gufasha mu gukemura ibimenyetso bya dementia niba rivastigmine itagukwiriye. Uburyo busanzwe burimo donepezil (Aricept) na galantamine (Razadyne), bikora kimwe na rivastigmine ariko bishobora kugira ingaruka zitandukanye.

Muganga wawe ashobora kandi gutekereza memantine (Namenda), ikora mu buryo butandukanye ikarinda selile z'ubwonko kwangirika. Abantu bamwe bungukirwa no guhuza memantine na cholinesterase inhibitor nka rivastigmine.

Usibye imiti, ikipe yawe y'ubuzima ishobora gushyira mu bikorwa ubuvuzi bwo mu mutwe, imyitozo ngororamubiri, ibikorwa by'imibereho, n'imibereho ishobora gushyigikira ubuzima bw'ubwonko. Ubu buryo bukora neza iyo buhuriye n'imiti ikwiye.

Ese Rivastigmine iruta Donepezil?

Rivastigmine na donepezil zombi ni imiti ikora neza mu kuvura indwara ya demance, ariko zikora mu buryo butandukanye kandi zishobora gukwira abantu batandukanye. Nta muti n'umwe uruta undi - guhitamo neza biterwa n'ubuzima bwawe bwite n'uko witwara ku miti.

Rivastigmine ishobora kuba nziza niba ugira ikibazo cyo kumira ibinini, kuko iboneka mu buryo bwa patch na liquid solution. Patch irashobora gufasha cyane abantu bibagirwa gufata imiti ya buri munsi cyangwa bafite ingorane zikomeye zo kumira.

Donepezil ishobora kuba nziza niba wumva vuba ibibazo byo mu gifu, kuko akenshi itera ingaruka nke zo mu gifu. Ifatwa kandi rimwe ku munsi, abantu bamwe babona ko byoroshye kuruta rivastigmine ifatwa kabiri ku munsi.

Muganga wawe azatekereza ibintu nk'indi miti ufata, indwara ufite, n'ibyo ukunda kugirango agushakire umuti mwiza. Abantu bamwe bashobora gukenera kugerageza imiti yombi kugirango barebe iyikora neza.

Ibibazo Bikunze Kubazwa Kuri Rivastigmine

Ese Rivastigmine irakwiriye abantu barwaye indwara z'umutima?

Rivastigmine irashobora gukoreshwa neza ku bantu benshi barwaye indwara z'umutima, ariko muganga wawe azagomba kugukurikiranira hafi. Uyu muti rimwe na rimwe ushobora kugira ingaruka ku mutima, bityo ni ngombwa kuganira ku ndwara yawe y'umutima mbere yo gutangira kuvurwa.

Muganga wawe ashobora kugusaba ibizamini byo gukurikiranira hafi umutima cyangwa guhindura urugero rw'umuti bitewe n'uburwayi bwawe bw'umutima. Abantu benshi barwaye indwara z'umutima zidakomeye bafata rivastigmine nta kibazo, cyane cyane iyo indwara yabo y'umutima ifashwe neza.

Nigira iki niba mfata rivastigmine nyinshi ku buryo butunguranye?

Niba ufata rivastigmine nyinshi, vugana na muganga wawe ako kanya cyangwa uhamagare umuntu ushinzwe uburozi kuri 1-800-222-1222. Gufata doze zinyongera bishobora gutera isesemi ikabije, kuruka, gucika amazi menshi mu kanwa, ibyuya, ndetse no kugabanya umuvuduko w'umutima ku buryo buteye akaga.

Ntugerageze kwivuruguta niba utabitegetswe n'abaganga. Bika icupa ry'umuti hamwe nawe igihe ushaka ubufasha kugira ngo abaganga bamenye neza icyo wafashe n'ingano yacyo.

Niba umuntu atagishobotse, afite ibibazo byo guhumeka, cyangwa agaragaza ibimenyetso by'uburozi bukomeye, hamagara 911 ako kanya. Ubufasha bwihuse bw'ubuvuzi bushobora gukumira ingorane zikomeye ziterwa no kurenza urugero.

Nkwiriye gukora iki niba nciwe urugero rwa Rivastigmine?

Niba wibagiwe gufata urugero rwa rivastigmine, rufate uko wibuka, keretse igihe cyegereye urugero rukurikira. Muri urwo rubanza, reka urugero wibagiwe ukomeze gahunda yawe isanzwe - ntuzigere ufata urugero ebyiri icyarimwe.

Niba wibagiwe urugero rwinshi rukurikirana, vugana na muganga wawe mbere yo kongera gufata umuti. Muganga wawe ashobora gukenera kongera kugutangiza ku rugero ruto kugira ngo wirinde ingaruka ziterwa n'umuti, cyane cyane niba umaze iminsi myinshi utawufata.

Gushyiraho ibyibutso bya buri munsi kuri terefone yawe cyangwa gukoresha umuteguro w'imiti birashobora kugufasha kwibuka gufata rivastigmine buri gihe. Gufata imiti buri gihe bifasha kubungabunga urugero rwawo ruzigama mu mubiri wawe.

Nshobora guhagarika ryari gufata Rivastigmine?

Ugomba guhagarika gufata rivastigmine gusa ukurikiza amabwiriza ya muganga wawe, kabone niyo wumva ko bitagufasha. Guhagarika ako kanya bishobora gutuma ibimenyetso byawe bya dementia birushaho kwiyongera vuba, ibyo bishobora kukubabaza wowe n'umuryango wawe.

Muganga wawe ashobora kugusaba guhagarika rivastigmine niba ugize ingaruka zikomeye ziterwa n'umuti, niba uburwayi bwawe burushaho kugera ku gihe umuti utagifasha, cyangwa niba ukeneye guhindurira ku bundi buryo bwo kuvurwa.

Umwanzuro wo guhagarika rivastigmine ugomba gufatwa buri gihe nk'igice cy'ikiganiro cyuzuye ku bijyanye n'uburyo bwawe bwose bwo kwitabwaho. Muganga wawe azagufasha kwimukira mu buryo bwo kuvura bundi mu buryo bwizewe niba bibaye ngombwa.

Nshobora kunywa inzoga niba mfata Rivastigmine?

Ni byiza kugabanya cyangwa kwirinda inzoga igihe urimo gufata rivastigmine, kuko inzoga ishobora gutuma ingaruka z'umuti zirushaho kuba mbi kandi ikabangamira imikorere yawo. Inzoga ishobora kongera isereri, urujijo, no kuribwa mu nda, ibyo bikaba bishobora kuba byarateye impungenge kuri rivastigmine.

Niba uhisemo kunywa rimwe na rimwe, biganireho na muganga wawe mbere na mbere. Ashobora kukugira inama ku birebana n'umubare w'inzoga ufite umutekano ukurikije ubuzima bwawe muri rusange n'uko witwara ku muti.

Wibuke ko inzoga ishobora no gutuma ibimenyetso bya demansiya birushaho kuba bibi ku giti cyayo, bityo kugabanya kunywa inzoga bishobora kugirira akamaro ubuzima bwawe bwo mu mutwe bitarenze gusa kwirinda imikoranire y'imiti.