Tangira na 600 mg y'isupulementi ya NAC rimwe ku munsi hamwe n'ibiryo bike, uhagarare aho icyumweru kimwe, hanyuma ugabanye ibipimo byose hejuru ya 600 mg mu gitondo no nimugoroba. Tegereza ibisubizo kuva ku cyumweru cyangwa icumi n'ibiri, ntabwo ari bibiri. Gura ibipimwe n'impuzamashyirahamwe, kuko FDA itemeze ibiri ku rupapuro rwa label.

TL;DR: Ibikubiye mu ncamake

  • Igipimo cyo gutangiriraho: 600 mg rimwe ku munsi igihe cy'icyumweru kimwe mbere yuko uhindura ikintu.
  • Icyerekezo cyo kugabana: hejuru ya 600 mg ku munsi, iyigabanye mu gitondo no nimugoroba, kuko igihe cyo kugumamo mu maraso ari amasaha 6 kugeza 8.
  • Igihe: ubushakashatsi bwakorewe ku bipimo bisanzwe byamaze ibyumweru 8 kugeza 12 cyangwa birushijeho, rero usubire gutekereza icyo gihe aho kuba ku cyumweru cya kabiri.
  • Imitako y'amategeko: FDA yahisemo NAC mu gusobanura suplemen y'ibiryo, bityo kwemeza n'impuzamashyirahamwe ni bwo buryo bwawe bwo kumenya ubuziranenge.
  • Ibibujijwe byikomeye bibiri: imiti ya nitrate na G6PD inzobere mu gusuzuma. Bose bakeneye umuganga mbere y'isupu ya mbere.

FDA yanzuye ko suplemen yawe ya NAC atari amategeko

Suplemen ya NAC ni capsule cyangwa ifu ya N-acetyl cysteine, akomoka kuri amino acid itera glutathione, antioxidant y'ingenzi mu mubiri wawe. Uburenganzira bwayo bwo mu mategeko burihariye. FDA yemeje ko NAC itujuje ibisabwa by'amategeko ku suplemen y'ibiryo, kuko acetylcysteine yemejwe nk'umuti mbere yuko uwugurisha nk'isupulementi. Ibicuruzwa bisigara ku masahani kubera kwihanganira kugirango bikoreshwe, ntabwo ari ubweme buhoraho cyangwa igenzura.

Niba wumvise ko NAC yahagaritswe, icyo cyemezo ni cyo gisobanura impamo mu mvugo y'ibihuha. Mu buyobozi bwawo bwa nyuma bwo mu mwaka wa 2022 ku bijyanye no kwihanganira ibicuruzwa bimwe na bimwe bya NAC, kigo cyasobanuye ko NAC yahisemo mu gusobanura suplemen kuko yemejwe nk'umuti mushya, nk'umuti wo mu biribwa by'ibinure byinshi ndetse n'umuti wo mu bihumeka by'umwuka, mbere yuko igurishwa nk'isupulementi. Uru ru rubi rugaragaza ko FDA izafata ibikorwa ku bicuruzwa byanditse nk'isupulementi byonyine niba ibyo bicuruzwa byari kuba byiza nk'isupulementi yemerwa n'amategeko, ntibyarenga ibindi biteganywa by'itegeko rya FD&C, kandi ntibyagize ikibazo cy'ubuzima mu igenzura rya FDA. Ku mpera ya 2023 kigo cyashyizeho kandi isuzuma ry'ubuhanga bwa n'ubuhanga bw'inyandiko z'ubuzima bwa NAC kuri gahunda yacyo yo gusuzuma, bivuze ko ubuzima bw'igihe kirekire bw'isupulementi buri mu igenzura rya leta aho kuba mu bwumvikane.

Ibyavuyemo byoroheje. Nta muntu ugereka miliyarima kuri buto yawe, bityo urebe ibipimwe n'impuzamashyirahamwe, USP, NSF cyangwa Informed Choice, kandi usome miliyarima kuri capsule aho kuba kuri serivisi, kuko serivisi ya 600 mg ikunze kuba capsules ebyiri. Ni ikibazo kimwe cyo gutegura nko kumenya niba Nutrafol ari impamo.

Hafi ya buri suplemen ya NAC ihumura ikubaka molecule imwe: glutathione

Hafi ya buri suplemen ya NAC ihumura ikubaka molecule imwe, ni yo mpamvu urutonde rw'ibicuruzwa rugera ku ngingo icyenda zikomoka kuri ubu buryo bumwe. NAC itanga cysteine, ingano y'ingenzi yo gukora glutathione, kandi isubiramo ry'umwaka wa 2021 ry'impact ya NAC ku buzima bw'abantu rivuga ko yongera glutathione mu nteko, irwanya imikorere y'ubuntu cyane, kandi igabanya inflammation yatewe na NF-kB harimo TNF-alpha na interleukins.

Ugereranya suplemen ya NAC n'uburyo bwerekana ibimenyetso, kandi ibice biratandukana neza. Kwifashisha mu bihumeka ni cyo gikomeye: isubiramo ry'ubuvuzi ryo muri 2009 rivuga ko 600 kugeza 1200 mg ku munsi bigabanya ibibazo bya COPD, hamwe n'umubare ukenewe wo kwita ku bantu 5.8 kugira ngo habeho ikibazo kimwe. Icya kabiri ni ugukoresha kwiyongera mu mitwe, aho isubiramo ry'umwaka wa 2018 ry'NAC mu ndwara zo mu mutwe ryasangaga igabanuka ry'umubare w'ibimenyetso by'agahinda n'ibigize schizophrenia ku bipimo bigera kuri 2000 kugeza 2400 mg ku munsi byakoreshwaga hamwe n'imiti yo mu mutwe, mu gihe ibisubizo by'ibibazo by'ubwoba no guhinduka kwa mood bikomeje kuba bibangamira kandi ntibyujuje ibisabwa. Igice cyoroheje ni icyo ikwamamaza ishishikariye cyane: gutunganya, uruhu, isukari mu maraso, ubudahangarwa, n'ikirego cy'uburumbuke cyangwa imwe mu ngamba zo kwirya no kwirinda bibaho mu rwego rwo kongera umubare w'imitsi y'ingabo.

Dore ibyo benshi bashobora kutakubwira: buri suplemen muri izo za NAC byakoreshwaga hamwe n'umuti wa acetylcysteine ufite ubwoko bwa farumasi mu bushakashatsi bwakorewe, ntabwo ari capsule ucuruza kuri interineti.

Igipimo gikwiriye cya NAC gitewe n'intego yawe, ntabwo ari serivisi yanditse kuri label

Nta gipimo kimwe cya NAC cy'ukuri, kandi umubare wanditse ku buto yawe ni gahunda yo gukora ibicuruzwa no kwamamaza kuruta ko ari ubw'ubuvuzi. Isupulementi zigera kuri 600 kugeza 1800 mg ku munsi kuko izo ngingo zihura neza mu ma capsule, ntabwo kuko hari umuntu wagaragaje ko intego yawe ikeneye 1800 mg.

Soma ibi bikurikira nk'ikoreshwa mu bushakashatsi bwakorewe ku bifashishwa n'imiti, ntabwo ari nk'itegeko ryawe.

  • Wambere wifashishije: 600 mg rimwe ku munsi igihe cy'icyumweru kimwe, ari na yo nsize yo kugurishwa kandi ni igipimo cyiza cyo kureba uko igifu cyawe gikora.
  • Kwihumeka cyangwa kwitaho rusange: 600 kugeza 1200 mg ku munsi, mu rwego rwakoreshejwe mu bushakashatsi bwo kwirinda ibibazo bya COPD, aho ibipimo kugeza kuri 1200 mg kabiri ku munsi byari byoroheje.
  • Ikibanza cyo mu mutwe: hafi 2000 kugeza 2400 mg ku munsi byakoreshejwe muri schizophrenia, kandi bikwiye kuba munsi y'ubuyobozi bw'umuganga hamwe n'ivuriro ry'ubu, ntabwo ari ahantu ho kwisuzuma wenyine.

Imibare ibiri igira ingaruka ku buryo wifashisha ibi. Igice cyo mu maraso ni amasaha 6 kugeza 8, ni yo mpamvu igipimo cya NAC ku munsi hejuru ya 600 mg cyiza kugabana mu gitondo no nimugoroba kuruta kunywa icyarimwe. Kandi hejuru ya 2000 mg ku munsi, ikibazo gikomeye ntikiba igifu cyawe ahubwo gikaba ingorane yo kurwara indwara ya hemolytic anemia kubantu bafite G6PD inzobere mu gusuzuma, niho igisabwa ko ubusobanuro budasanzwe bw'isukari bukora.

Ibyo bikwiranye n'amategeko, bivuga ko ubwoko bw'ibintu bikomeye bya acetylcysteine ​​bukoreshwa mu kwirinda kw'ibitotsi bikoreshwa mu kwirinda ibitotsi byo mu irinde, kandi ntabwo ari igipimo cya NAC kugomba kwigana mu rugo, kandi ntabwo ari cyo kiri muri buto yawe.

Tangira na 600 mg, uyigabane, kandi uhitemo ibyumweru umunani mbere yo kubisuzuma

Kumenya uko wakoresha NAC bigizwe no guhitamo, kwishyiramo, no kwihangana, muri iyo ntambwe. Kora izi ntambwe esheshatu rimwe kandi ibisigaye ni ugukomeza.

  1. Hitamo ifomu. Impapuro ni izambere: kwirinda ibyiyumvo by'umunyu, byoroshye kubara. Ifu ni cyo cyoroheje kandi ifite impumuro mbi cyane. Agasanduku k'amazi y'isupu bica byoroshye ku gifu, ariko wibaze isukari. Imibiri yakozweho byihuse iramamaza kubw'uburyo bwiza, ihagaze cyane, kandi ifite impamvu nyinshi kuri iyo mvugo. Icyo waba uhisemo, hitamo kimwe cyapimwe n'impuzamashyirahamwe kubw'impamvu z'ikigereranyo.
  2. Shyiraho igipimo cyo gutangiriraho. 600 mg rimwe ku munsi. Ntugatangire na 1800 mg kuko label yerekana ko ari capsules eshatu.
  3. Shyirayo mu munsi. Ku kibazo cy'igihe cyiza cyo gufata NAC, igifu cy'ubusa gitanga ubwoko bwiza, ariko niba wumva umunaniro cyangwa uterwa isesemi, ibiryo bike bidafite amata ni byiza, kandi ubwoko bw'ubwoko bw'ubwoko bw'ubwoko bushobora kwemerwa buruta ubwoko budashobora kwemerwa. Bikure kure y'igihe cyo kuryama niba bigutera impagarike, kandi bifate icyarimwe buri munsi.
  4. Gabanura iby'umubare wa 600 mg. Hamwe na 6 kugeza 8 yo kugumamo mu maraso, 1200 mg nk' 600 mg mu gitondo na 600 mg nimugoroba bigumana urwego ruhagije kuruta 1200 mg mu gihe kimwe.
  5. Andika kandi wihanganire gahoro. Ongera wiyongereho ikigero cya 600 mg rimwe mu cyumweru, kandi uhagarare ku gipimo cyoroheje cyane gikora akazi. Porogaramu yo kwita ku buzima nka August AI irashobora kugufasha kwandika ibipimo, igihe, n'ibyakorewe nk'igikoresho cyo kwita ku buzima bwawe aho kuba ikintu cyo gufata ibyemezo.
  6. Soma ubushakashatsi kuva ku cyumweru cya 8 kugeza 12. Ubushakashatsi bwo mu bihumeka n'ubw'ubuvuzi bwakorewe kuva icyo gihe cyangwa birushijeho, bityo icyumweru cya kabiri ntacyo kiguvuna. Track ingingo z'ibimenyetso, umwuka, imbaraga, n'imyumvire, kandi ugere mu rwego rwa mbere.

Impumuro, ntabwo ari ingorane, ni yo mpamvu abantu benshi bahagarika NAC

Ibyakorewe ku ngaruka za NAC bikomeye ku bantu benshi ntibibabaza, birakaze, kandi iryo tandukaniro rifite icyo risobanura kuko birashobora gukosorwa. Gutera ibibazo by'igifu ni ikibazo gikunda kubaho, hamwe n'umunaniro n'gusya byavugwaga ku rugero rwa 23% by'abakoresha b'inzira, akenshi bifitanye isano n'impumuro y'umunyu y'umubiri.

Gukora ingorane mbere yuko uhagarika. Shyirira ifu mu capsule cyangwa capsule ifunze. Ifate hamwe n'ibiryo bike bidafite amata. Kumanuka kuri 300 mg kabiri ku munsi. Noneho wongera gushyiramo nyuma y'icyumweru cy'igipimo cyoroheje. Impumuro y'umunyu cyangwa guhumeka, impinduka zoroheje, umutwe, n'umunaniro byoroheje bikunda kugenda uko ugumye, kandi ntabwo ari impamvu zo guhagarika.

Urutonde rutandukanye kandi ruto cyane rwerekeza ku guhagarara uyu munsi no gusuzumwa: inzara cyangwa indwara, gutontoma, kwishushya cyangwa kwiruka, cyangwa umunyu wijimye.

Niba umunaniro utagabanyije nyuma yuko uhinduye uburyo n'igipimo, cyangwa niba inzara cyangwa gutontoma bigaragara, gusura kwa August ku $39 kuri interineti bikuganisha ku umuganga ufite uruhushya muri Leta Zunze Ubumwe z'Amerika ushobora kubisuzuma kandi ugahabwa uburenganzira niba biboneka ko byakwiye. Umuganga ni we ufata icyo cyemezo, ntabwo ari ugusubira. Gusura kwa telehealth ntibikoreshwa mu kwirinda kwiruka, anaphylaxis, cyangwa ikindi kintu cyose kiri ku rutonde rw'ibikorwa byihutirwa.

Abantu batatu bagombye gutangira NAC badashishikajwe n'umuganga mbere

Ibihugu bitanu byakenera ikiganiro mbere y'isupu ya mbere. Abakoresha imiti ya nitrate baraza mbere, kuko NAC yongera cyane ingaruka za nitroglycerin zo kugabanya umuvuduko w'amaraso, bigatera ingorane yo kugabanya cyane umuvuduko w'amaraso n'umutwe, bityo witondere cyangwa wirinde NAC ku ntwara iyo ari yo yose ya nitrate, ibipfuke cyangwa amavuta. Abantu bafite G6PD inzobere mu gusuzuma cyangwa anemia batarimo impamvu bagombye kwisuzumisha bakareba amaraso mbere, kuko hemolysis ariyo ngorane yo gupima. Abafite asthme cyangwa ibibazo byo guhumeka bagombye kubibaza umuganga wabo. Kimwe n'abakoresha imiti ikoreshwa mu guhagarika amaraso cyangwa bafite indwara yo kwiruka, n'uwafashe pirfenidone.

Wahamagare 911 cyangwa ujye mu cyumba cy'ibitaro byihutirwa ubu niba:

  • Utekereza ko wabuze ibitotsi, wishakiye cyangwa uko byagenze. Hamagara abashinzwe ubumenyi bw'ibituruka ku bintu ku 1-800-222-1222 cyangwa ujye mu bitaro byihutirwa. Suplemen ya NAC idafite uburenganzira ntaho ihuriye n'ibipimo bivugwa ku buryo bw'ubuvuzi by'umuti cyangwa ubw'abantu bikoreshwa mu kwirinda.
  • Ugaragaza inzara, kwishima mu maso cyangwa mu muhogo, gutontoma cyangwa ibibazo byo guhumeka nyuma y'igipimo.
  • Ufite inzoka, umunyu wijimye cyangwa ububabare bukomeye mu gifu.
  • Ufite umutwe ukomeye wo mu ijuru ufite ibyo ubona, ubwoba cyangwa amaraso make cyane mugihe ukoresha nitroglycerin cyangwa indi nitrate.

Uzakore igenzura mu cyumweru gitaha niba:

  • Umunaniro cyangwa gusya bikomeje nyuma yo guhindura uburyo n'igipimo.
  • Ugaragaza kwishushya cyane, cyangwa umunaniro n'ibyo ubona bishobora gusobanura anemia.
  • Ntabwo wabonye inyungu nyuma y'ibyumweru 12 ku gipimo gihamye.

Vugana n'umuganga mbere yuko utangira niba:

  • Ufata kimwe mu miti yavuzwe haruguru, cyangwa utwite cyangwa ushobora k Bonsa.
  • Wigeze ugira reaction yo guhumeka.
  • Utekereza igipimo kiri hejuru ya 1800 mg ku munsi.

Ntabwo wizeye icyiciro uriho? August AI Symptom Checker yishimishije irashobora kugufasha gutandukanya ibihutirwa n'ibisanzwe mbere yuko utekereza aho ugiye.

Bikunze kubazwa

Birashoboka ko mfata NAC n'izindi suplemen nka vitamin C, zinc, cyangwa selenium?

Yego. Nta mbaraga zihamye hagati ya NAC n'imyunyu ngugu isanzwe yo mu bwoko bwa antioxidant cyangwa vitamin C, kandi akenshi bazifata hamwe. Ariko, ubyumve gusa, kandi wongereho ibicuruzwa kimwe icyarimwe buri cyumweru hagati y'igihe. Niba ibintu bitatu byatangiye icyarimwe kandi wumva utameze neza, ntuzabona uburyo bwo kumenya icyabiteye.

NAC irizewe gufata mugihe utwite cyangwa umubyeyi?

Ntabwo bisanzwe bikorewe ku gitekerezo. Acetylcysteine ​​ikoreshwa mugihe utwite mu bihe bimwe na bimwe by'ubuvuzi bikorwa, ariko ntabwo bihura no gufata suplemen nk'ubushake, kandi uburyo bwa suplemen ntaho buhura n'uburyo bw'ubuvuzi bwa mbere mu gihe utwite.

NAC ifasha mu kwirinda indwara z'ubusinzi cyangwa kurinda igifu cyanjye nanyweye inzoga?

Rimwe na rimwe byavugwa, kenshi ntibyerekana. Uburyo burashoboka, kuko gutunganya inzoga bikoresha glutathione, ariko nta bushakashatsi bw'abantu bugaragaza ko NAC yirinda ibimenyetso by'ubusinzi cyangwa ko ihagarika inzoga nyinshi. Kuyikoresha nk'ubwishingizi bw'igifu ni cyo kibazo nyamukuru hano, kuko ishobora guhindura ingano y'inzoga wemera kunywa mu gihe ntacyo udufashije ku gifu cyawe.

Nakoresha NAC, cyangwa nshobora kuyifata buri munsi ubuzima bwose?

Oya, nta gahunda yo gusubiramo ishingiye ku bimenyetso, bityo gufata ikiruhuko ku kalendari isanzwe ni igitekerezo. Ubwoko bwo kwihanganira ni ugusubiramo buri mwaka n'uwagukoresha: wemeze ko ikigukorera ikintu ufite uburyo bwo gusobanura, wemeze ko urutonde rw'imiti yawe rutarahinduka, kandi uhagarike niba igisubizo cyawe kivugisha ukuri ari uko nta kintu cyahindutse.

Suplemen ya NAC iruta gufata glutathione imbona n'imbona?

Ntabwo bisanzwe. Suplemen ya NAC itanga cysteine ​​ingufu zigikoresha mugukora glutathione yazo, ni ubwoko bw'uburyo bushakashatsi bwose bwakorewe. Oral glutathione igomba kwihanganira igogora ryose, kandi ubuhanga bw'abantu kuri ibyo buracyari bwo kandi budahwanya. NAC kandi ihendutse cyane kuri buri kwezi, ibyo bifite icyo bisobanura mu mwaka.

Abangavu bashobora gufata NAC kubw'ibiribwa cyangwa ubuzima bwo mu mutwe?

Rimwe na rimwe, ariko ku buyobozi bw'abaganga b'abana cyangwa abangavu. Ubushakashatsi ku rubyiruko buhari kubibazo bimwe na bimwe byo mu mutwe, kandi byakorewe hamwe n'igenzura, isuzuma ry'ibanze n'ikimenyetso cyavuzwe. Kubibazo by'uruhu hari bike cyane byo kureba. Igipimo cy'umwana ntabwo ari igipimo cy'umwana gusa, kandi ibimenyetso by'ubuzima bw'umutwe mu rubyiruko bikwiye kuba byisuzumwe neza mbere na mbere.

Ibisobanuro bifatika ku gufata NAC

Tangira suplemen ya NAC na 600 mg rimwe ku munsi hamwe n'ibiryo bike, kandi ugabanye iby'umubare wa 600 mg mu gitondo no nimugoroba. Muhe ibyumweru 8 kugeza 12 mbere yuko utangira gutekereza niba yaguhaye uruhushya mu buzima bwawe bwa buri munsi. Gura ibipimwe n'impuzamashyirahamwe, kuko FDA itemeze label yawe. Kandi usuzume imiti ya nitrate n'ikibazo cya G6PD mbere y'isupu ya mbere.

Kwirinda: Inyandiko iri ni iy'amakuru gusa kandi ntabwo ifatwa nk'ubujyanama bw'ubuvuzi. Jya uhura n'umuganga ufite ubuzima bwiza kugira ngo ubone ibisubizo n'ibyemezo by'ubuvuzi. Niba ufite ikibazo cy'ubuvuzi, wahamagara 911 cyangwa ujye mu cyumba cy'ibitaro byihutirwa.