Chii chinonzi Dutasteride: Zvinoshandiswa, Madosi, Mativi eMuviri uye Zvimwe

Dutasteride mushonga unopiwa nachiremba unonyanya kushandiswa kurapa benign prostatic hyperplasia (BPH), mamiriro apo prostate gland inokura. Mushonga uyu ndewemukirasi yemishonga inonzi 5-alpha reductase inhibitors, iyo inoshanda nekudzivisa mahomoni anokonzera kukura kweprostate. Kunyange dutasteride ichinyanya kunyorerwa matambudziko eprostate, dzimwe nguva inoshandiswa kunze kwemavara ekuita baldness yemurume, kunyangwe izvi zvisiri zvaro zvakanyanya zvinoshandiswa.

Chii chinonzi Dutasteride?

Dutasteride mushonga we synthetic unotarisa ma enzymes chaiwo mumuviri wako. Inovharira ese marudzi e5-alpha reductase enzymes, ayo ane basa rekushandura testosterone kuita dihydrotestosterone (DHT). DHT ihomoni inogona kukonzera kuti prostate yako ikure uye inobatsira kurasikirwa nevhudzi mumurume.

Mushonga uyu une simba kupfuura mamwe mishonga yakafanana nekuti inovharira ese marudzi e enzyme, zvichiita kuti ive inoshanda zvakanyanya mukuderedza mazinga eDHT. Iwe unowanzoona dutasteride ichitengeswa pasi pemazita emhando seAvodart, uye inouya sekapsule ye gelatin yakapfava yaunomedza yese.

Chii chinonzi Dutasteride Chinoshandiswa?

Dutasteride inonyanya kunyorerwa kurapa benign prostatic hyperplasia (BPH) muvarume. BPH kukura kusingaite kenza kweprostate gland iyo inogona kukonzera zviratidzo zvisingafadzi zveurinary senge kuoma kutanga kuita weti, kuyerera kweweti kusina simba, uye nguva dzose kuenda kuchimbuzi usiku.

Mushonga uyu unobatsira kudzikisa prostate yakakura nekufamba kwenguva, iyo inogona kuvandudza kugona kwako kuita weti zvakajairika. Vamwe vanachiremba vanonyorawo dutasteride kunze kwemavara ekuita baldness yemurume (androgenetic alopecia), kunyangwe kushandiswa uku kusina kubvumidzwa zviri pamutemo neFDA. Zvakanakira kurasikirwa nevhudzi zvinowanika nekuti DHT inobatsirawo mukudzikiswa kwevhudzi follicle uye pakupedzisira kurasikirwa nevhudzi.

Dutasteride Inoshanda Sei?

Dutasteride inoshanda nekudzivisa ma enzyme e 5-alpha reductase mumuviri mako wese. Ma enzyme aya anowanzo shandura testosterone kuita DHT, hormone ine simba rakawanda rinokurudzira kukura kweprostate uye kudzikira kwemvere.

Nekuderedza mazinga eDHT neanosvika 90%, dutasteride inobvumira prostate yako yakakura kuti idzoke zvishoma nezvishoma kune saizi yakajairika. Iyi nzira inowanzo tora mwedzi yakati wandei, sezvo tishu yeprostate isingachinji husiku humwe. Mushonga uyu unoonekwa seune simba rakawanda kana uchienzaniswa nemishonga yakafanana nekuti inodzivisa mhando mbiri dze enzyme, zvichikonzera kuderedzwa kwakanyanya kweDHT.

Funga nezvazvo sekudzima vhoriyamu pa hormone yave ichikonzera matambudziko. Nekuderera kweDHT ichitenderera mumuviri mako, kumanikidzwa pa prostate yako nemafollicle emvere kunoderera nekufamba kwenguva.

Ndingatora sei Dutasteride?

Tora dutasteride sezvakanyorwa nachiremba wako, kazhinji kamwe pazuva panguva imwe chete zuva rega rega. Unogona kuitora uine chikafu kana usina, sezvo zvekudya zvisinganyanyi kukanganisa maitiro emuviri wako anotora mushonga.

Medza capsule yese usina kuipwanya, kuitsenga, kana kuivhura. Mushonga uri mukati unogona kutora kuburikidza neganda rako, izvo zvinogona kukonzera mhedzisiro isingadiwi. Kana ukangoerekana wabata zvirimo, geza maoko ako zvakakwana nesipo nemvura.

Edza kugadzira tsika neku tora mushonga wako panguva imwe chete zuva rega rega. Vanhu vazhinji vanozviwana zvichibatsira kutora dutasteride netsika yavo yemangwanani kana kudya kwemanheru kuti vabatsirwe kuyeuka. Kuenderana kunobatsira kuchengetedza mazinga akagadzikana emushonga mumuviri mako.

Ndingatora Dutasteride kwenguva yakareba sei?

Dutasteride inowanzoita kurapwa kwenguva refu kwaunozofanira kuenderera mberi chero iwe uchida kuchengetedza mabhenefiti ayo. Varume vazhinji vane BPH vanoi tora zvachose, sezvo kumisa mushonga kunobvumira mazinga eDHT kudzokera kune zvakajairika uye zviratidzo kudzoka.

Munogona kutanga kuona kuvandudzika muzviratidzo zveweti mukati memwedzi mitatu kusvika mitanhatu mushure mekutanga kurapwa. Zvisinei, zvakanakisa zvinowanzo tora mwedzi mitanhatu kusvika gumi nemiviri kuti zvikure zvizere. Panyaya yekurapa kurasikirwa kwebvudzi, mhedzisiro inogona kutora nguva yakareba kuti ioneke, dzimwe nguva kusvika kumakore maviri.

Chiremba wako achatarisa kufambira mberi kwako kuburikidza nekutarisa nguva dzose uye anogona kugadzirisa chirongwa chako chekurapa zvichienderana nekuti uri kupindura sei. Usambofa wakamira kutora dutasteride kamwechete usina kuzvikurukura nemupi wako wehutano, sezvo izvi zvinogona kutungamira kudzoka kwezviratidzo zvako zvepakutanga.

Ndezvipi Zvakaipa zveDutasteride?

Semishonga yese, dutasteride inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anozviwana. Mhedzisiro yakajairika ine chekuita nebasa repabonde uye inowanzoita nani nekufamba kwenguva sezvo muviri wako uchigadzirisa kumishonga.

Heano mhedzisiro yaungasangana nayo, yakarongwa kubva kune yakajairika kusvika kune isingawanzoitiki:

Mhedzisiro yakajairika (inoita kusvika ku10% yevashandisi):

• Kuderera kwechido chepabonde (libido)
• Kutadza kuwana kana kuchengeta kumira
• Kuderera kwehuwandu hwemvura yembeu panguva yekubuda
• Kutapira kwemazamu kana kuwedzera
• Dizziness

Mhedzisiro isingawanzoitiki asi inocherechedzwa:

• Kushungurudzika kana shanduko dzemafungiro
• Meno eganda kana kukwenya
• Kurwadziwa kwemazamu kana kuzvimba
• Kutadza kubuda
• Kukura kwebvudzi pamuviri

Mhedzisiro isingawanzoitiki asi yakakomba inoda kutariswa kwekurapa nekukurumidza:

• Maitiro akakomba ekuita allergic (kufema kwakaoma, kuzvimba kwechiso, miromo, rurimi, kana huro)
• Kutanga kamwechete kwemazamu kana kubuda
• Kushungurudzika kwakanyanya kana pfungwa dzekuzvikuvadza
• Zviratidzo zvematambudziko echiropa (kuita yero yeganda kana maziso, weti yakasviba, kurwadziwa kwakanyanya mudumbu)

Mhedzisiro zhinji dzinowanzoita dzakapfava uye dzenguva pfupi, asi zvakakosha kuti ukurukure chero zvaunonetseka nazvo nachiremba wako. Vanogona kukubatsira kuyera mabhenefiti achipesana nenjodzi dzinogona kuitika uye vanogona kukurudzira nzira dzekugadzirisa mhedzisiro kana dzikaitika.

Ndiani Asingafaniri Kutora Dutasteride?

Dutasteride haina kukodzera munhu wese, uye mapoka akati wandei evanhu anofanira kudzivisa mushonga uyu zvachose. Vakadzi, kunyanya avo vane pamuviri kana vangave nepamuviri, havafaniri kutora dutasteride kana kutobata makapisi.

Aya ndiwo mapoka makuru asingafaniri kushandisa dutasteride:

Zvinopesana zvachose (usambofa wakatora dutasteride kana uine izvi):

• Vakadzi vechero zera (mushonga unogona kukonzera zvikanganiso zvekuzvarwa)
• Vana nevechiri kuyaruka vari pasi pe18
• Kuziva allergy ku dutasteride kana finasteride
• Chirwere chakakomba chechiropa

Shandisa nekuchenjerera kwakanyanya kana kudzivisa (kurukura zvakadzama nachiremba wako):

• Nhoroondo yekudzvinyirirwa kana mamiriro ehutano hwepfungwa
• Matambudziko echiropa kana ma enzymes echiropa akakwira
• Kenza yegurokuro kana mazinga epamusoro ePSA
• Nhoroondo yekenza yemazamu
• Zvirongwa zvekuvhiyiwa kwegurokuro munguva pfupi iri kutevera

Chiremba wako achatarisa nhoroondo yako yekurapa uye mishonga iripo usati wanyora dutasteride. Iva akatendeseka zvizere nezve mamiriro ako ehutano uye chero zvinowedzera zvaunotora, sezvo izvi zvinogona kukanganisa kana dutasteride yakachengeteka kwauri.

Mazita eDutasteride Brand

Dutasteride inowanikwa pasi pemazita akati wandei emhando, Avodart ndiyo inonyanya kuzivikanwa uye yakanyorwa zvakanyanya. Avodart inogadzirwa neGlaxoSmithKline uye ndiyo yaive chigadzirwa chekutanga chedutasteride chakabvumirwa neFDA.

Mhando dzakajairika dze dutasteride dziripo zvakare uye dzine chinhu chimwe chete chinoshanda seiyo brand-name vhezheni. Izvi zvingasarudzwa zvakajairika zvinowanzo shoma mari asi zvichipa mabhenefiti akafanana ekurapa. Murapi wako wemishonga anogona kukubatsira kunzwisisa kuti ndeipi vhezheni inofukidzwa neinishuwarenzi yako uye kana kutsiva kwakajairika kwakakodzera kwauri.

Zvimwe zvigadzirwa zvekubatanidza zviripo zvakare, senge Jalyn, iyo ine dutasteride netamsulosin. Aya mishonga yekubatanidza akagadzirirwa varume vanoda zvese prostate shrinkage uye nekukurumidza kubatsirwa nezviratidzo.

Dzimwe nzira dzeDutasteride

Dzimwe nzira dze dutasteride dziripo dzekurapa BPH uye kupera bvudzi revarume. Sarudzo pakati pezvingasarudzwa zvinoenderana nezviratidzo zvako zvakakosha, nhoroondo yako yekurapa, uye zvinangwa zvekurapa.

Pekurapa BPH, chiremba wako angangofunga izvi zvimwe:

Mishonga mimwe:

• Finasteride (Proscar) - yakafanana asi isina simba kudarika dutasteride
• Alpha-blockers senge tamsulosin (Flomax) - inopa nekukurumidza kubatsirwa nezviratidzo
• Kurapa kwekubatanidza kunosanganisira ese marudzi emishonga

Kurapa kusiri kwemishonga:

• Nzira shoma dzinopinda senge UroLift kana Rezum
• Laser therapy (GreenLight, HoLEP)
• Sarudzo dzekuvhiya dzechinyakare senge TURP
• Kugadziridzwa kwehupenyu kusanganisira shanduko dzekudya uye maekisesaizi epelvic

Pekurasikirwa nebvudzi, dzimwe nzira dzinosanganisira topical minoxidil, nzira dzekuisa bvudzi, kana low-level laser therapy. Chiremba wako anogona kukubatsira kuongorora izvi zvingasarudzwa zvichibva pamamiriro ako ega uye zvaunofarira.

Dutasteride iri nani kudarika Finasteride here?

Dutasteride nefinasteride zvese zviri 5-alpha reductase inhibitors, asi zvinoshanda zvishoma zvakasiyana mumuviri wako. Dutasteride inovharira ese marudzi eiyo enzyme (Type I uye Type II), nepo finasteride ichinyanya kuvharira Type II.

Musiyano uyu unoita kuti dutasteride ive inoshanda zvakanyanya pakuderedza mazinga eDHT - inogona kuderedza DHT ne90% zvichienzaniswa nekuderedzwa kwe70% kwefinasteride. Pakurapa BPH, izvi zvinowanzo shandurwa kuita kuvandudzwa kwakanaka kwezviratidzo uye kuderedzwa kukuru kwehuwandu hwe prostate nekufamba kwenguva.

Zvisinei, "zvirinani" zvinoenderana nemamiriro ako ega. Finasteride yanga iripo kwenguva refu uye ine data yakawanda yekuchengeteka kwenguva refu. Inogonawo kukonzera mhedzisiro shoma mune vamwe varume. Mhedzisiro yakasimba yeDutasteride inogona kubatsira varume vane maprostates makuru kana zviratidzo zvakanyanya, asi inogonawo kuwedzera njodzi yemhedzisiro.

Chiremba wako achafunga nezvezvinhu zvakaita sekuoma kwezviratidzo zvako, saizi ye prostate, mhinduro dzakapfuura dzekurapa, uye kushivirira njodzi paunenge uchisarudza pakati pemishonga iyi. Zvese zviri zviviri zvinoshanda, uye sarudzo yakanakisa inosiyana kubva kumunhu nemunhu.

Mibvunzo Inowanzo Bvunzwa Nezve Dutasteride

Dutasteride Yakachengeteka Here Kune Zvirwere Zvemoyo?

Dutasteride inowanzoonekwa seyakachengeteka kune varume vane chirwere chemoyo, sezvo isingakanganisi zvakananga basa remoyo kana kudzvinyirirwa kweropa. Kusiyana nemimwe mishonga yeBPH, dutasteride haikonzeri shanduko huru mumoyo kana kudzvinyirirwa kweropa izvo zvinogona kuwedzera mamiriro emoyo aripo.

Zvisinei, iwe unofanirwa kuzivisa chiremba wako nezve chero matambudziko emoyo usati watanga dutasteride. Vamwe varume vane chirwere chemoyo vanotora mishonga yakawanda, uye chiremba wako anofanira kuona kuti hapana hukama. Uyezve, kana iwe uchitora zvinoderedza ropa kana uine kuvhiyiwa kwemoyo kwemazuva ano, chiremba wako anogona kuda kukutarisa zvakanyanya.

Mhedzisiro yebonde ye dutasteride inogona kusanzwisisika kukanganisa vamwe varume vane chirwere chemoyo, sezvo chiitiko chepabonde chiri chimiro chekurovedza muviri. Kana iwe uine chirwere chemoyo chakakomba uye uchinetseka nezve chiitiko chepabonde, kurukura izvi nachiremba wako wemoyo.

Ndingaita Sei Kana Ndikashandisa Dutasteride Yakawandisa Netsaona?

Kana ukatora dutasteride yakawanda kupfuura yakanyorerwa netsaona, usavhunduka. Kudya kwakawanda kwe dutasteride kamwe chete hakuzokonzeri kukuvadza kwakanyanya nekukasira, asi unofanirwa kutora matanho nekukurumidza.

Taura nachiremba wako kana wemishonga nekukasira kuti utaure nezvekuwedzera kwemishonga uye uwane gwara rakajeka. Kana wakatora huwandu hukuru kana uri kusangana nezviratidzo zvinonetesa sekutemwa nemusoro kwakanyanya, kusvotwa, kana kuoma kufema, fonera masevhisi ekukurumidzira kana kuenda kuchipatara chekukurumidzira chiri pedyo.

Usaedze kuzviita kuti urutse kunze kwekunge wakanzi nevanopa hutano. Chengeta zvakanaka kuti wakatora mishonga yakawanda sei uye rini, sezvo ruzivo urwu ruchabatsira nyanzvi dzezvekurapa kuti dzizive nzira yakanakisa yekutora. Mberi, funga kushandisa chirongwa chemishonga kana kumisa zviyeuchidzo zvefoni kubatsira kudzivirira kukanganisa kwemishonga mune ramangwana.

Ndoita Sei Kana Ndikakanganwa Dose ye Dutasteride?

Kana ukakanganwa dose ye dutasteride, itore paunorangarira, kunze kwekunge yava nguva yechikamu chako chinotevera. Muchiitiko ichocho, siya dose yakakanganwa uye uenderere mberi nechirongwa chako chekudya mishonga.

Usambofa wakatora zvikamu zviviri panguva imwe chete kuti ugadzirise dose yakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yezvinetso. Dutasteride ine hafu-hupenyu hurefu, zvinoreva kuti inogara mumuviri wako kwemazuva akati wandei, saka dzimwe nguva kukanganwa dose hakuzokanganisi zvakanyanya kurapwa kwako.

Kana iwe uchikanganwa zvikamu kazhinji, edza kumisa alarm yezuva nezuva pafoni yako kana kushandisa chirongwa chemishonga chine zvikamu zvemazuva evhiki. Kuenderana kwakakosha pakuchengeta mazinga emahormone akagadzikana uye kuwana mhedzisiro yakanakisa kubva mukurapa kwako.

Ndingamira Rini Kutora Dutasteride?

Haufanire kumira kutora dutasteride usati wataurirana nachiremba wako. Mishonga iyi inowanzo fanirwa kutorwa kwenguva refu kuti ichengetedze mabhenefiti ayo, uye kumira kamwe kamwe kunogona kukonzera kuti zviratidzo zvako zvidzoke mukati memwedzi mishoma.

Chiremba wako angangofunga kumisa dutasteride kana ukawana matambudziko asingashiviriki, kana mamiriro ako asiri kuvandudzika mushure menguva yakakwana, kana kana ukawana mamwe matambudziko ehutano anoita kuti mushonga usakodzere. Vanogonawo kukurudzira kumisa kana uri kuronga maitiro emishonga.

Kana ukamira kutora dutasteride, tarisira kuti mazinga ako eDHT adzokere zvishoma nezvishoma kune zvakajairika mumwedzi yakati wandei. Izvi zvinoreva kuti prostate yako inogona kutanga kukura zvakare, uye zviratidzo zveurinary zvinogona kudzoka. Chiremba wako anogona kukubatsira kuronga shanduko iyi uye kukurukura dzimwe nzira dzekurapa kana zvichidikanwa.

Ndingagona Kupa Ropa Ndiri Kutora Dutasteride?

Nzvimbo zhinji dzekupa ropa hadzizogamuchire zvipo zveropa kubva kuvarume vari kutora dutasteride, uye unofanira kumirira angangoita mwedzi mitanhatu mushure mekumisa mushonga usati wapa. Chenjedzo iyi iripo nekuti dutasteride inogona kuramba iri muropa rako kwemwedzi uye inogona kukuvadza fetus iri kukura kana ropa rikapihwa kumukadzi ane pamuviri.

Kudziviswa kunoshanda kunyangwe mazinga e dutasteride muropa rakapihwa angave akaderera kwazvo. Nzvimbo dzekupa ropa dzinokanganisa kune chenjedzo kana zvasvika kumishonga inogona kukanganisa mhedzisiro yekuzvitakura.

Kana iwe uchitora dutasteride uye uchida kupa ropa, unozofanirwa kukurukura kumisa mushonga nachiremba wako kutanga. Vanogona kukubatsira kuyera mabhenefiti ekupa ropa pamwe nekudzoka kunogona kuitika kwezviratidzo zvako zveBPH panguva yekumirira.