Uma udokotela wakho ekuxilonge une-urinary tract infection (UTI), ungase uzibuze ukuthi i-Bactrim noma i-Macrobid iyona engcono kuwe. Zombili lezi zihlabathi ezilwa namagciwane ziyasebenza ekwelapheni ama-UTI, kodwa ziyasebenza ngendlela ehlukile emzimbeni wakho futhi zilungele izimo ezahlukene. Udokotela wakho ukhetha eyona engcono kakhulu ngokusekelwe emlandweni wakho wezempilo, uhlobo lwamagciwane olubangela ukugula kwakho, nokuthi umzimba wakho uphendula kanjani imithi.

Iyini i-Bactrim neMacrobid?

I-Bactrim yimali yokulwa namagciwane eyakhiwe ngokuhlanganisa imithi emibili: i-sulfamethoxazole ne-trimethoprim. Le mithi emibili isebenza ndawonye ukuze ivimbele amagciwane ukuthi angakhiqizi izakhamzimba azidingayo ukuze aphile futhi azalisane. Uma amagciwane ehluleka ukukhiqiza lezi zakhiwo ezibalulekile, ekugcineni ayabulawa, lokhu kusiza umzimba wakho ukuba uphole ekuguleni.

I-Macrobid, ngakolunye uhlangothi, iqukethe i-nitrofurantoin kuhlobo olukhethekile olukhululwa kancane kancane. Le mithi yokulwa namagciwane igxila ngqo emchameni wakho esikhundleni sokusabalala kulo lonke umzimba wakho. Icekela phansi i-DNA yamagciwane futhi iphazamisa amandla abo okukhiqiza amandla, okuyinto ebabulala ngempumelelo lapho ukugula kuhlala khona ohlelweni lwakho lomchamo.

Zombili lezi mishanguzo ziye zasetshenziswa iminyaka eminingi ukwelapha ama-UTI. Zombili zinezinhlangothi eziqinile ezizenza zilungele abantu abahlukene nezimo ezahlukene. Ukuqonda lezi zinto ezihlukile kukusiza ukubona ukuthi kungani udokotela wakho angakhetha enye kunenye esimweni sakho esithile.

Le mithi yokulwa namagciwane iyasebenza kanjani ngendlela ehlukile emzimbeni wakho?

I-Bactrim ingena egazini lakho futhi ihambe kulo lonke uhlelo lwakho. Lokhu kusho ukuthi ingakwazi ukwelapha izifo ezindaweni ezahlukene, okubalwa kuzo uhlelo lwakho lomchamo, amaphaphu, uhlelo lokugaya ukudla, ngisho nesikhumba. Umzimba wakho uyisebenzisa esibindini nasezinso zakho, futhi uvamise ukuyithatha kabili ngosuku ngengilazi egcwele yamanzi.

I-Macrobid isebenza ngendlela eqondile. Ngemva kokuyigwinya, umzimba wakho uyayumunca futhi uwuhluze ngokushesha ngezinso zakho bese uya emchameni wakho. Isofike ezingeni eliphezulu lapho kwenzeka khona i-UTI yakho. Le ndlela eqondile kusho ukuthi isebenza ngqo ezingomeni zesinye, hhayi ezindaweni ezisemzimbeni wakho.

Indlela ngayinye yomuthi ehamba emzimbeni wakho ithinta ukuthi ingasebenza kahle kangakanani ezinhlotsheni ezahlukene zezifo. I-Bactrim ingafika ezinso zakho futhi iphathe izifo ezibucayi kakhulu lapho. I-Macrobid isebenza kangcono ezingomeni zesinye ngoba igxila emchameni wakho kodwa ayifiki ezingeni elanele ezicutini zezinso ukuze iphathe izifo zezinso ngempumelelo.

Izinso zakho zidlala indima enkulu endleleni le mithibio esebenza ngayo. Uma izinso zakho zingasebenzi kahle, i-Macrobid ingase ingahlaliseki kahle emchameni wakho. I-Bactrim ingasebenza nasezinkingeni ezincane zezinso, kodwa odokotela kudingeka balungise umthamo ngokucophelela noma bakhethe omunye umuthi wokulwa namagciwane uma umsebenzi wezinso zakho wehla kakhulu.

Yiziphi izifo ngayinye imithi yokulwa namagciwane eyehlulwa kakhulu?

I-Macrobid ihamba phambili ekwelapheni izifo ezingaluhluphi zesinye, odokotela abazibiza ngokuthi yi-cystitis. Lezi ama-UTI aqondile lapho amagciwane enqala khona isinye sakho kodwa angazange afinyelele ezinso zakho noma egazini lakho. Uma uba nomuzwa wokusha lapho wenza umchamo, izidingo ezivamile zokuchama, nokungakhululeki esiswini esingezansi, i-Macrobid ngokuvamile iyayiphatha kahle lezi zifo eziqondile zesinye.

I-Bactrim inikeza ukusebenza okukhulu ngoba ifika ezingeni elanele kulo lonke uhlelo lwakho. Udokotela wakho angayikhetha ngezingomeni zesinye, izifo zezinso (pyelonephritis), noma lapho kunezingqinamba ezifana nesifo sikashukela noma izinkinga zesakhiwo ohlelweni lwakho lomchamo. Iphinde iphathe izifo ngaphandle kohlelo lomchamo, okwenza ibe usizo uma udokotela wakho esola izinkinga eziningi noma isifo esinzima.

Ezifweni zezinso ikakhulukazi, i-Bactrim ngokuvamile iyona engcono. Lapho amagciwane esuka esinye sakho eqonda ezinso zakho, udinga imithi yokulwa namagciwane efinyelela ezingeni elifanele ezicutini zezinso. I-Macrobid ayikwazi ukufinyelela lokhu, ngakho odokotela ngokuvamile bayigodlela kuphela izifo ezansi ohlelweni lomchamo ezihlala esinye.

Uma uhlangabezana nama-UTI avamile, udokotela wakho angase anikele ngomunye wale mithibio ukuze uvikele, nakuba benza lokhu ngendlela ehlukile. I-Macrobid ingathathwa ngomthamo ophansi isikhathi eside ukuvimbela izifo zesinye. I-Bactrim ingasebenza nasekugcineni, kodwa odokotela bacubungula izinzuzo ngokumelene nemiphumela emibi kakhulu ngenxa yokusebenza kwayo okubanzi emzimbeni wakho.

Yimiphi imiphumela emibi ongayithola ngomunye umuthi?

Yonke imithi inemiphumela emibi engaba khona, futhi ukwazi ukuthi yini ongayilindela kukusiza uzizwe ulungile kunokuba ukhathazeke. Iningi labantu libhekana kahle ne-Bactrim ne-Macrobid, kodwa umzimba wakho ungase uphendule ngendlela ehlukile kumunye nomunye.

Nge-Macrobid, ungase uqaphele ukuphazamiseka okuncane kokugaya ukudla njengoba umzimba wakho ulungisa umuthi. Nansi imiphumela evamile abantu abayithola:

• Ukucasuka noma ukuphazamiseka okuncane esiswini, ikakhulukazi uma uyithatha esiswini esingenalutho

• Ikhanda elivame ukuba nelula futhi lidlule ngokushesha

• Ukulahlekelwa isifiso sokudla phakathi nonyango

• Umbala omnyama womchamo, obukeka uyingozi kodwa ongalimazi futhi ongokwesikhashana

• Isiyezi noma ukuzizwa ulula kancane uma umi

Le miphumela ngokuvamile ihlala ilula futhi iyathuthuka njengoba umzimba wakho ujwayela umuthi. Ukuthatha i-Macrobid ngokudla kuvame ukunciphisa isicanucanu kakhulu.

I-Bactrim ingadala izimpawu ezifanayo zokugaya ukudla, kodwa futhi inezinye izinto okufanele uzicabangele ngoba ithinta wonke umzimba wakho esikhundleni sokugxila ohlelweni lomchamo kuphela. Imiphumela ejwayelekile ihlanganisa:

• Isicanucanu, ukuhlanza, noma ukuphazamiseka okujwayelekile esiswini

• Ukulahlekelwa isifiso sokudla okungase kuzwakale kakhulu kunokuba ne-Macrobid

• Ukuzwela okuncane kwesikhumba ekukhanyeni kwelanga, okukwenza ube namathuba okushiswa ilanga

• Ikhanda elisukela kokulula kuye kokumaphakathi

• Isiyezi noma ukuzizwa ukhathazekile ngokwengqondo

Iningi labantu libhekana nale miphumela ngaphandle kwezinkinga eziningi, kodwa ukugcina amanzi omzimba kahle nokuthatha umuthi ngokudla kusiza umzimba wakho ukuba uwusebenzise kahle.

Kukhona imiphumela emibi ebucayi okufanele uyibheke?

Nakuba iningi labantu lithatha le mithi yokulwa namagciwane ngaphandle kwezinkinga ezinkulu, imiphumela engavamile kodwa ebucayi ingenzeka. Ukwazi izimpawu zokuxwayisa kusho ukuthi ungathola usizo ngokushesha uma kwenzeka okuthile okungajwayelekile.

Nge-Macrobid, imiphumela engavamile ebucayi kakhulu ihilela amaphaphu nesibindi sakho. Abanye abantu bathola ukuvuvukala kwamaphaphu, odokotela abakubiza ngokuthi i-pulmonary toxicity. Lokhu kungenzeka ngokushesha ngemva kwemithamo embalwa noma kuthuthuke kancane uma uthatha umuthi isikhathi eside. Bheka ukuntula ukuphefumula okusha, ukukhwehlela okuqhubekayo, ubuhlungu besifuba, noma ubunzima bokuphefumula. Lezi zimpawu zidinga ukunakekelwa kwezokwelapha ngokushesha.

Izinkinga zesibindi ziyinye ingozi engavamile kodwa ebucayi nge-Macrobid. Isibindi sakho siyawusebenzisa umuthi, futhi kwezinye izimo ezingavamile, singavuvukala. Izimpawu zihlanganisa ukuba nombala ophuzi wesikhumba noma amehlo akho (jaundice), umchamo omnyama obukeka njenge-tea, izitulo ezikhanyayo, ukukhathala okubucayi, noma ubuhlungu esifubeni sakho esingezansi kwesokudla. Uma uqaphela lezi zimpawu, thintana nodokotela wakho ngokushesha.

Ukulimala kwezinzwa, nakuba kungavamile kakhulu, kungenzeka ngokusebenzisa i-Macrobid isikhathi eside. Ungase uzizwe ukuluma, ukuba ne-numbness, noma ukuzizwa okungajwayelekile ezandleni noma ezinyaweni zakho. Lokhu kwenzeka kakhulu kubantu abayithatha izinyanga kunokuba izinyanga ezimbalwa. Udokotela wakho uyalibheka leli thuba uma udinga unyango olude.

I-Bactrim inezinye izinselele ezingavamile kodwa ezibucayi okufanele zinakekelwe. Imiphumela ye-allergy ebucayi yenzeka kakhulu nge-Bactrim kunangama-Macrobid, ikakhulukazi kubantu abane-allergy emidlalweni ye-sulfa. Le miphumela ingabeka kusukela ezinsheni ezilula kuya ezimweni ezingadala ukufa.

I-Stevens Johnson syndrome yiyona umphumela omubi wesikhumba ongaba khona nge-Bactrim. Lesi simo esingavamile siqala ngezimpawu ezifana nomkhuhlane zilandelwa yinsheni ebuhlungu ebusela futhi ifake amabhamuza. Isikhumba sakho singase sikhwele, futhi ungathola izilonda emlonyeni wakho, emehlweni, noma ezithweni zokuzala. Lesi simo esiphuthumayo sezokwelapha sidinga ukwelashwa esibhedlela ngokushesha. Yeka umuthi bese ufuna usizo oluphuthumayo uma uthola noma iyiphi inshensha esheshayo enama-blister noma isikhumba esikhwele.

Izinkinga zamangqamuzana egazi zingenzeka nge-Bactrim ngoba ithinta indlela umnkala wakho ukhiqiza ngayo izangqamuzana zegazi. Ungathola amazinga aphansi amangqamuzana amhlophe, amangqamuzana abomvu, noma ama-platelets. Izimpawu zokuxwayisa zihlanganisa ukubetheka noma ukopha okungajwayelekile, ukukhathala okwedlulele, isikhumba esiluhlaza okwesibhakabhaka, umkhuhlane, noma umphimbo obuhlungu. Udokotela wakho angase aqhube izivivinyo zegazi ngaphambi naphakathi nonyango uma uthatha i-Bactrim isikhathi esingaphezu kwezinsuku ezimbalwa.

Amazinga aphezulu potassium angenzeka nge-Bactrim, ikakhulukazi uma usunobudlelwano obuthile nezinso noma uthatha eminye imithi. I-Potassium eningi kakhulu ithinta i-heart rhythm yakho. Tshela udokotela wakho uma uzwa ukushaya kwezinhliziyo okungajwayelekile, ubuthakathaka bemisipha, noma ukuzizwa ukozela. Abantu abanezifo zezinso noma abathatha imithi egcina i-potassium kudinga ukubhekelwa ngokukhethekile.

Ukuvuvukala kwesibindi kungenzeka nge-Bactrim futhi, okufana ne-Macrobid. Izimpawu zokuxwayisa ezifanayo ziyasebenza: i-jaundice, umchamo omnyama, izitulo ezikhanyayo, noma ubuhlungu besifuba esingezansi. Nakuba kungavamile, lo mphumela kusho ukuyeka umuthi ngokushesha.

Ubani okufanele agweme umuthi wokulwa namagciwane?

Izimo ezithile zezempilo zenza omunye umuthi wokulwa namagciwane uphephe kunomunye kuwe. Udokotela wakho ucabanga ngesimo sakho sezempilo esiphelele ngaphambi kokunikezela ngomunye wale mithibio.

Akufanele uthathe i-Macrobid uma izinso zakho zingakwazi ukuhlunga udoti kahle. Lapho umsebenzi wezinso wehla ngaphansi kwezinga elithile, i-Macrobid ingahlaliseki kahle emchameni wakho ukuze ibulale amagciwane. Iphinde iqoqane egazini lakho ezingeni elingadala ubuthi.

Isikhathi sokukhulelwa sibalulekile nge-Macrobid. Ngokuvamile kuphephile phakathi nengxenye enkulu yokukhulelwa, kodwa odokotela bayayigwema ngasekhunjini lakho. Umuthi ungabanga izinkinga ezinyenganeni ezinsukwini zazo zokuqala zokuphila, ikakhulukazi uma zinokushodelwa yi-enzyme esibindini esitholakala emindeni ethile. Uma use kuwe inyanga yokugcina yokukhulelwa noma usuzobeletha, udokotela wakho uzokhetha omunye umuthi wokulwa namagciwane.

Abantu abane-glucose 6 phosphate dehydrogenase deficiency, odokotela abayibiza ngokuthi yi-G6PD deficiency, akufanele bathathe i-Macrobid. Lesi simo esingezansi sigcina izangqamuzana zegazi elibomvu, futhi i-Macrobid ingabangela ukuba zihlakazeke ngokushesha. Lokhu kudala i-anemia ebucayi edinga ukwelashwa ngokushesha. Lesi simo sivame kakhulu kubantu abavela e-Afrika, eMeditera, noma e-Asia.

I-Bactrim inemikhawulo ehlukile odokotela abayicabangelayo ngokucophelela. Uma une-allergy emidlalweni ye-sulfa, i-Bactrim ayikho ngoba iqukethe i-sulfamethoxazole. Ama-allergy e-sulfa angadala noma yini kusukela ezinsheni ezilula kuye ezimweni ezingadala ukufa.

Ukukhulelwa nokuncelisa kuyadinga ukucophelela okwengeziwe nge-Bactrim. Ingaphazamisa i-folic acid metabolism, edingwa yizingane ukuze zikhule kahle. Odokotela ngokuvamile bayayigwema phakathi nenyanga yokuqala nangasekhunjini. Ngesikhathi sokuncelisa, i-Bactrim ingena obisini lwebele futhi ingathinta ingane yakho, ikakhulukazi izinsana noma izingane ezizalwe ngaphambi kwesikhathi.

Isifo sesibindi esibucayi senza i-Bactrim ibe yingozi kakhulu ngoba isibindi sakho sisiza ukucubungula umuthi. Uma isibindi sakho singakwazi ukwenza lokhu ngempumelelo, umuthi uyaqoqana futhi wandise amathuba emiphumela emibi. Udokotela wakho ubahekelela kangakanani umsebenzi wesibindi sakho noma ukhethe enye indlela uma unezinkinga ezinkulu zesibindi.

Abantu abanezimo ezithile zegazi kufanele basebenzise i-Bactrim ngokucophelela noma bangasebenzisi nhlobo. Uma unama-cell count aphansi, izinkinga zomnkala, noma i-anemia ngenxa yokushodelwa kwe-folate, i-Bactrim ingenza la ma-condition abe mabi kakhulu. Udokotela wakho ubheka izibalo zegazi lakho nomlando wakho wezempilo ngokucophelela ngaphambi kokunikezela ngayo.

Uyiqonda kanjani imithi ngayinye kahle?

Ukuthatha imithi yakho yokulwa namagciwane njengoba inikeziwe kusiza ukuba isebenze kahle futhi kunciphise amathuba emiphumela emibi. Umuthi ngayinye unayo imiyalelo ethile eyenza ukusebenza kwawo kube okungcono emzimbeni wakho.

I-Macrobid iza ngama-capsule ovame ukuwathatha kabili ngosuku, cishe amahora angu-12. Ukuyithatha ngokudla kusiza umzimba wakho ukuba uyumunce kangcono futhi kunciphisa kakhulu isicanucanu. Zama ukuyithatha ngesidlo noma ukudla okuncane esikhundleni sokuyithatha esiswini esingenalutho. Gwinya i-capsule lonke ngaphandle kokuyichoboza, ukuyiluma, noma ukuvula ngoba isihlanganiso esikhethekile sikhulula umuthi kancane kancane emzimbeni wakho.

Iningi lezingomeni zesinye ludinga izinsuku ezinhlanu kuya kweziyisikhombisa zokwelashwa nge-Macrobid. Ungase uqale ukuzizwa kangcono ngemva kwezinsuku ezimbalwa, kodwa ukuqedela lonke uhlelo kuqinisekisa ukuthi wonke amagciwane ayabulawa. Ukuyeka ngaphambi kwesikhathi kuvumela amagciwane aqine ukuba aphile futhi azalisane, okungabuyisa ukugula kwakho kube kubi kakhulu kunangaphambili.

Ukuphuza amanzi amaningi ngenkathi uthatha i-Macrobid kusiza ukuhlanza amagciwane ohlelweni lwakho lomchamo futhi kukugcine ukhululekile. Zama okungenani izinkomishi eziyisithupha kuya kweziyisishiyagalombili ngosuku ngaphandle kokuthi udokotela wakho akunikeze imiyalelo ehlukile yokuphuza. Ukugcina amanzi omzimba kahle futhi kusiza ukuvimbela eminye imiphumela emibi.

Amatafula e-Bactrim avame ukuba khona ngamavolumu ajwayelekile noma aphindwe kabili. Udokotela wakho ukunikeza umthamo ngokusekelwe ohlobo nokuqina kokugula kwakho. Iningi lama-UTI ludinga umuthi kabili ngosuku, cishe amahora angu-12. Njenge-Macrobid, ukuthatha i-Bactrim ngokudla kunciphisa ukuphazamiseka esiswini futhi kukusiza ukuba uwubekezele kangcono.

Ukuphuza amanzi engeziwe nge-Bactrim kubaluleke kakhulu ngoba kusiza ukuvimbela ukwakheka kwamatshe ezinsweni. Zama ukuphuza ingilazi egcwele yamanzi ngomthamo ngamunye futhi ugcine amanzi omzimba kahle usuku lonke. Lesi sinyathelo esilula sinciphisa kakhulu ingozi yemiphumela emibi ehlobene nezinso.

Ubude bonyana bokwelashwa nge-Bactrim buyehluka kuye ngokugula kwakho. Izifo zesinye eziqondile zingase zidinge izinsuku ezintathu kuya kwezinhlanu, ngenkathi izifo zezinso zivame ukudinga izinsuku eziyishumi kuya kweziyishumi nane. Izifo ezinzima kakhulu zingase zidinge izikhathi eziningi nakakhulu. Udokotela wakho unquma isikhathi esilungile sesimo sakho esithile.

Ukubeka izikhumbuzi zefoni kukusiza ukuba ukhumbule imithamo ngesikhathi esilungile. Ukuxhumanisa isikhathi njalo kugcina amazinga omuthi emzimbeni wakho, okubulala amagciwane ngempumelelo kakhulu. Uma uphuthelwa umthamo, uwuthatha ngokushesha lapho uwukhumbula ngaphandle kokuthi kuseduze isikhathi somthamo wakho olandelayo. Ungalokothi uphindaphinde imithamo ukuze ubuyekeze ngoba lokhu kukwandisa amathuba emiphumela emibi ngaphandle kokusiza umuthi usebenze kangcono.

Uyozizwa kangakanani ungcono ngokushesha?

Mhlawumbe ucindezela ukuzwa ukukhululeka ezimpawini zakho ezingakhululeki. Ukuqonda isikhathi kukusiza ukwazi ukuthi yini ongayilindela njengoba umuthi uqala ukusebenza.

Iningi labantu liqaphela ukuthuthuka okuthile phakathi kwezinsuku eyodwa kuya kwezimbili zokuqala omunye wale mithi yokulwa namagciwane. Umuzwa wokusha wakho ungase unciphe, futhi ungase ungazizwa usadinga ngempela ukuchama njalo. Lokhu kuthuthuka kusencane kubonisa ukuthi umuthi uyafinyelela ohlelweni lwakho lomchamo futhi uqala ukubulala amagciwane.

Ukuthola impumuzo ephelele ezimpawini ngokuvamile kuthatha izinsuku ezintathu kuya kwezinhlanu ngomunye wale mithibio. Ngalesi sikhathi, iningi lamagciwane libe libulawe, ukuvuvukala esinye sakho kuyacisha, futhi uhlelo lwakho lomchamo luyalulama. Kufanele uzizwe kangcono kakhulu noma ubuyele esimweni sakho esijwayelekile ngokuphelele.

Uma ungazitholi nhlobo ukuthuthuka ngemva kwezinsuku ezimbili kuya kwezintathu, thintana nodokotela wakho. Lokhu kungase kusho ukuthi amagciwane abangela ukugula kwakho ayamelana nomuthi wokulwa namagciwane owuthathayo. Udokotela wakho angakushintshela kwenye imithi noma aqhube izivivinyo ezengeziwe ukuze athole amagciwane athile kanye nokubekezela kwawo.

Ngokuvamile uzizwa ungcono ngokuphelele ngaphambi kokuphothula uhlelo lwakho lokulwa namagciwane. Lokhu kungakulingela ukuba uyeke ukuwuthatha, kodwa sicela umelane nalolo hlobo lokuluma. Amagciwane angase abe khona ngisho lapho izimpawu zinyamalala. Ukuqedela uhlelo oluphelele kuvimbela ukugula ukuba kubuye futhi kunciphisa amathuba okuba namagciwane aqine.

Ungakwazi yini ukuba ne-resistance kule mithi yokulwa namagciwane?

Ukuba ne-resistance kwemithi yokulwa namagciwane kwenzeka lapho amagciwane ehlala ejwayela imithi eyayiwabulala kalula. Le nkinga ekhulayo ithinta kokubili i-Bactrim ne-Macrobid, nakuba ngendlela ehlukile kulo lonke izindawo ezahlukene.

I-Bactrim resistance inyuke kule minyaka eminingi ezindaweni eziningi. Amagciwane abangela ama-UTI, ikakhulukazi i-E. coli (ejwayelekile kakhulu), aqhamuke ngezindlela zokuhlala endaweni yokudalulwa ngalo muthi. Amazinga e-resistance ahlukahluka ngendawo, kodwa kwezinye izindawo, amaphesenti angamashumi amabili kuya kwamashumi amathathu amagciwane abangela ama-UTI angamelana ne-Bactrim.

Lokhu akusho ukuthi i-Bactrim ayisasebenzi. Udokotela wakho uvame uku-oda i-urine culture ngaphambi kokuyinikezela, ikakhulukazi uma uhlangabezana nezifo eziphindaphindayo. Lesi sivivinyo sichaza amagciwane athile abangela ukugula kwakho futhi sibonise ukuthi yimiphi imithi yokulwa namagciwane ezoyibulala ngempumelelo. Uma isiko lakho libonisa ukubekezela ku-Bactrim, izosebenza kahle kuwe.

I-Macrobid igcine ukusebenza kangcono ngokumelene namagciwane ajwayelekile e-UTI. Amazinga e-resistance ahlala ephansi kakhulu uma eqhathaniswa neminye imithi yokulwa namagciwane, okwenza ibe yinketho ebalulekile. Indlela yayo eyihlukile yokusebenza ohlelweni lwakho lomchamo kanye nezinye izindlela zayo zokubulala amagciwane kwenza kube nzima ukuba amagciwane akhethe i-resistance.

Ungasiza ukuvimbela i-resistance ngokuthatha imithi yakho yokulwa namagciwane njengoba inikeziwe. Ungalokothi uphuthelwe imithamo, uyeke ngaphambi kwesikhathi, noma ugcine amaphilisi asalele enye ingozi. Lezi zimikhuba zinikeza amagciwane ithuba lokuzivumelanisa nokuhlala. Ukusebenzisa imithi yokulwa namagciwane kuphela lapho idingeka ngempela ngezifo zamagciwane esikhundleni sezifo zamagciwane kusiza nokuphila phakade.

Yimuphi umuthi wokulwa namagciwane odula kakhulu?

Intengo ibalulekile lapho udinga umuthi, ikakhulukazi uma ukhokha imali yakho noma unezibambiso eziphezulu. Zombili i-Bactrim ne-Macrobid zitholakala njengezinhlobo zama-generics, okwenza zibe nezingabizi uma ziqhathaniswa neminye imithi yokulwa namagciwane emisha.

I-Bactrim ejwayelekile, ethengiswa njenge-sulfamethoxazole trimethoprim, ngokuvamile idula kancane kune-Macrobid ejwayelekile (nitrofurantoin). Isikhathi esijwayelekile se-Bactrim ejwayelekile singaba kusuka kumadola ambalwa kuye emadola ayishumi nanhlanu ngaphandle komshwalense, kuye ngekhemisi lakho nendawo yakho. Ngomshwalense, i-copay yakho ingase ibe ngisho naphansi.

I-Macrobid ejwayelekile idula kancane kodwa ihlala ingabizi kakhulu. Isikhathi ngokuvamile sisukela kumadola ayishumi kuya kwamashumi amathathu ngaphandle komshwalense. Kanye futhi, umshwalense uvame ukukunciphisa lokhu kube yi-copay encane. Ukwehlukana kwentengo phakathi kwale mibili ngokuvamile kungabi ngcono futhi akufanele kube isici esiyinhloko ekukhetheni unyango lwakho.

Izinhlobo zamagama ezidume kakhulu zidula kakhulu, kodwa izikhemisi eziningi zishintsha ngokuzenzakalela i-generic ngaphandle kokuthi udokotela wakho achaze ukuthi uhlobo lwesimilo lubalulekile ngokwezokwelapha. Imithi yokulwa namagciwane ejwayelekile iqukethe izakhiwo ezifanayo futhi isebenza ngokufanayo namagama adumile, ngakho-ke ahlinzeka ngenani elihle kakhulu.

Izindawo eziningi zamakhemisi zinikeza izinhlelo zokonga izindleko zokubhalisa noma amakhadi esaphulelo anciphisa izindleko kakhulu. Uma intengo ingeyona inkinga, khuluma nodokotela wakho nekhemisi mayelana nenketho engabizi kakhulu ezolapha ukugula kwakho ngempumelelo. Bavame ukuthola izindlela zokwenza umuthi wakho ufinyeleleke kakhulu.

Yimiphi imishanguzo enye ehlangana nale mithi yokulwa namagciwane?

Zombili i-Bactrim ne-Macrobid zingaxoxisana neminye imishanguzo oyithathayo. Ukwazi ngalezi zimpambana kusiza wena nodokotela wakho ukuvimbela izinkinga ngaphambi kokuba ziqale.

I-Macrobid ihlangana nemishanguzo embalwa kakhulu, okwenza kube lula ukuyisebenzisa ngemikhosi enye. Nokho, ezinye izimpambana ezibalulekile zifanele ukubhekwa. Ama-antacid aqukethe i-magnesium anganciphisa ukuthi umzimba wakho umunce kangakanani i-Macrobid. Uma udinga ama-antacid, uwathathe okungenani amahora amabili ngaphambi noma emva komthamo wakho wokulwa namagciwane.

Eminye imishanguzo ethinta ukuthi isisu sakho siyeka nini singaphazamisa ukumunca kwe-Macrobid. Lokhu kufaka phakathi imithi njenge-propantheline, ehamba kancane ukuvaleka kwesisu. Lapho i-Macrobid ihlala esiswini sakho isikhathi eside, ingadala isicanucanu esiningi, futhi umzimba wakho ungase ungayumunce kangcono.

I-Bactrim inamandla amakhulu okuxoxisana ngoba ithinta wonke umzimba wakho futhi ithinta indlela isibindi sakho esicubungula ngayo eminye imishanguzo. Ezinye izimpambana ezibalulekile zidinga ukuqapha okucophelela noma ukulungiswa komthamo.

Izidambisa zegazi njenge-warfarin zixoxisana kakhulu ne-Bactrim. Umuthi wokulwa namagciwane ungandisa imiphumela ye-warfarin, okwandisa ingozi yokuphuma kwegazi. Uma uthatha i-warfarin, udokotela wakho uzobheka izikhathi zakho zokubopha igazi ngokucophelela futhi angase alungise umthamo wakho we-warfarin okwesikhashana ngenkathi uthatha i-Bactrim.

Imishanguzo yesifo sikashukela, ikakhulukazi i-sulfonylureas njenge-glyburide noma i-glipizide, ingaba namandla kakhulu uma ihlangana ne-Bactrim. Lokhu kungalenza igazi lakho libe liphansi kakhulu, libangele i-hypoglycemia. Hlola igazi lakho kakhulu uma uthatha le mishanguzo ndawonye, ​​bheka izimpawu ezifana nokuthuthumela, ukujuluka, ukudideka, noma isifiso esingajwayelekile sokudla.

I-Methotrexate, esetshenziswa ngezimo ze-autoimmune nezinye izifo ezithile, iba enobuthi kakhulu lapho ithathwa ne-Bactrim. Zombili lezi mishanguzo zithinta i-folate metabolism, futhi ukuzihlanganisa kunganciphisa kakhulu amazinga amangqamuzana egazi akho futhi kubangele ezinye izinkinga ezibucayi. Udokotela wakho ngokuvamile uzokhetha omunye umuthi wokulwa namagciwane uma uthatha i-methotrexate njalo.

Eminye imishanguzo yokunqanda umfutho wegazi okubizwa ngokuthi i-ACE inhibitors noma i-angiotensin receptor blockers ingahlanganiswa ne-Bactrim ukunyusa amazinga akho potassium kakhulu. Lokhu kuthinta i-heart rhythm yakho. Udokotela wakho angabheka amazinga akho potassium ngokuhlolwa kwegazi uma uthatha le mishanguzo ndawonye.

I-Diuretics, ikakhulukazi amaphilisi amanzi afana ne-hydrochlorothiazide, angaxoxisana ne-Bactrim ukudala izinguquko zamangqamuzana egazi noma ukungalingani kwe-electrolyte. Udokotela wakho ubheka lezi zingozi ngokucophelela uma udinga imishanguzo yomibili ngesikhathi esifanayo.

Yini okufanele uyitshele udokotela wakho ngaphambi kokuthatha omunye umuthi wokulwa namagciwane?

Udokotela wakho udinga isithombe esiphelele sezempilo yakho ukuze akhethe umuthi wokulwa namagciwane ophephe kunazo zonke futhi osebenza kangcono kuwe. Ukuhlinzeka ngolwazi oluphelele kusiza ukuvimbela izinkinga futhi kuqinisekisa ukuthi unyango lwakho lusebenza kahle.

Qala ngokubala yonke imishanguzo oyithathayo manje, okubalwa phakathi kwayo imishanguzo kadokotela, imishanguzo ethengiswa ngaphandle kwe-counter, amavithamini, kanye nezithako zemvelo. Ezinye izithako zingaxoxisana nemithi yokulwa namagciwane noma zifihle izimpawu udokotela wakho okufanele azi ngazo. Letha amabhodlela emishanguzo yakho engxoxweni yakho noma ugcine uhlu oluvuselelwe efoni yakho.

Khuluma nganoma yimiphi imiphumela ye-allergy yangaphambili emishangweni, ngisho noma ibonakala ilula. Izinsheni, ama-hives, ukuvuvukala, ubunzima bokuphefumula, noma ukuluma okubucayi konke kubalulekile. Tshela udokotela wakho ngokukhethekile mayelana nemiphumela emidlalweni ye-sulfa, imithi yokulwa namagciwane, nanoma yimiphi imishanguzo. Ngisho noma ungakajwayelanga ukuthi yini ebangele imiphumela yangaphambili, ukuhlinzeka ngolwazi kusiza udokotela wakho ukuba enze izinketho eziphephile.

Khuluma nganoma yiziphi izimo zezempilo ezikhona, ikakhulukazi izifo zezinso, izifo zesibindi, izifo zegazi, noma izinkinga zamaphaphu. Lezi zimo zithinta ukuthi yimuphi umuthi wokulwa namagciwane osebenza kangcono futhi noma udinga ukulungiswa komthamo noma ukuqapha okwengeziwe. Yiba ngoqotho ngezimo ngisho noma zibonakala zingahlobene ne-UTI.

Uma ukhulelwe, uzama ukukhulelwa, noma uncwelisa, tshela udokotela wakho ngaphambi kokuthatha noma yimuphi umuthi wokulwa namagciwane. Izinqumo zokwelashwa ziyashintsha ngokusekelwe esigabeni sokukhulelwa nokuthi uyancelisa yini. Udokotela wakho uzokhetha inketho ephephe kunazo zonke kuwe nengane yakho.

Hlinzeka ngolwazi mayelana nama-UTI wangaphambili, okubalwa kuzo ukuthi uwathola kangaki futhi yimiphi imithi yokulwa namagciwane ebesebenza noma eyayingenzi msebenzi esikhathini esidlule. Uma uye waqhuba ama-urine cultures ngaphambili, imiphumela ebonisa ukubekezela kwamagciwane kusiza udokotela wakho ukuba akhethe umuthi osebenza kangcono manje.

Khuluma uma une-G6PD deficiency noma uma lesi simo singemndeni wakho. Leli thuba elingezansi lithinta ukuthi yimiphi imithi yokulwa namagciwane ephephile kuwe. Uma ungakaze uhlolwe kodwa unamakhaya ezindaweni lapho kuvamile khona, udokotela wakho angase aqhube ukuhlolwa.

Isiphetho

Themba inqubo futhi ulandele uhlelo lwakho lokwelashwa ngokucophelela. Thatha isikhathi sakho esiphelele semithi yokulwa namagciwane ngisho nalapho uzizwa ungcono, uphuze amanzi amaningi, futhi ubize uma kukhona okubonakala kungalungile. Iningi lama-UTI litholakalisa kahle ngomuthi wokulwa namagciwane ofanele, futhi uzobuya uzizwe njengawe njengasekuqaleni kakhulu. Impilo yakho ibalulekile, futhi unyango olusebenzayo lufinyeleleka ngokuphelele.