I-Amoxicillin ne-Alcohol: Ungaphuza, Kodwa Nansi Ingabe Kubiza Kanjani Ukululama Kwakho

Yebo. I-Amoxicillin ne-alcohol ayihlangani, futhi ilebula elamukelwe yi-FDA alinayo isexwayiso nge-alcohol nhlobo. Ukuphuza ngeke kubangele ukusabela noma kuyeke i-antibiotic isebenze. Intengo yangempela ingeyokululama kwakho: i-alcohol icindezela ukusabela komzimba okwenza uhhafu womsebenzi kanye nomuthi.

I-TL;DR: Okubalulekile okumele ukwazi

• Ungaphuza i-amoxicillin. Ileba ye-FDA, i-MedlinePlus kanye ne-NHS zonke azisho ukuthi kukhona umkhawulo we-alcohol.
• Insumansumansuwa ocabanga ngayo ingeyeye-metronidazole, eyenza ngempela ukusabela okufana ne-disulfiram. I-Tinidazole ne-Bactrim nazo kumele zibe kulolu hlu.
• Idosi ayinalutho. 250 mg, 500 mg, 875 mg, izihlafuno kanye ne-liquid suspension konke kunempendulo efanayo.
• Ukwelashwa okukodwa kuphela okuyikho ngempela: uma umuthi wakho uy-amoxicillin-clavulanate (Augmentin) uphuza kakhulu, uhlanganisa izinto ezimbili ezibeka isibindi engcupheni ngesikhathi esisodwa.
• Akukho sikhathi sokulinda ngemuva kwekhamera yakho yokugcina. Qonda lokhu ngokuthi uzizwa kanjani, hhayi amahora esikhathini.

Cha, i-amoxicillin ne-alcohol ayihlangani emzimbeni wakho

Ayikho indlela yokuthi i-amoxicillin ne-alcohol zihlangane. Imininingwane yamanje yokwelashwa egunyazwe yi-FDA ku-DailyMed ayinawo umkhawulo nge-alcohol, akuvimbeli noma ukusebenzisana kunoma iyiphi ingxenye yelebula. Ukuphuza ngeke kubangele ukusabela okuyingozi, futhi akukwazi ukuyekisa i-antibiotic ukuthi ibulale amagciwane. I-Amoxicillin iyingxenye ye-penicillin, futhi ama-penicillin akhiqizi ukusabela okufana ne-disulfiram okucatshangwayo.

Iziqondiso zabantu abasebenzisa imithi zisho into efanayo ngamazwi alula. I-MedlinePlus, evela ku-NIH National Library of Medicine, iyala abantu abasebenzisa i-amoxicillin ukuthi baqhubeke nokudla kwabo okuvamile ngaphandle kokuthi udokotela athi kungenjalo, futhi ayisho ukuthi kukhona umkhawulo we-alcohol phakathi kweziqwashiso zayo. I-I-NHS iphendula umbuzo ngokuqondile: yebo, ungaphunga i-alcohol ngenkathi usebenzisa i-amoxicillin.

Ngakho-ke izinkolelo ezimbili ezibanjwa cishe ngabantu bonke azilungile. I-alcohol ayenzi i-amoxicillin ibe yisihlava, futhi i-alcohol ayiyiqedi.

Intengo yangempela yokuphuza akuyona ukusabela, kodwa ukululama okuhamba kancane

Ngakho-ke ngabe i-alcohol iyayiyeka imithi yokubulala amagciwane ukuthi isebenze? Cha, futhi lokhu kufanele kuhlukaniswe ngokucacile kumbuzo obaluleke kakhulu. Umuthi uqhubeka nokubulala amagciwane ngesivinini esifanayo noma ngabe uphuze ibhiya noma cha. Okushintshayo ukuthi umzimba wakho uzobamba iqhaza kangakanani ndawonye nomuthi.

Lobu buqembu bungalinganiswa. Ukuphuza kakhulu noma ukuphuza ngokweqile kanye nje kungase kucindezela ukuxhumana kwe-cytokine ne-chemokine phakathi kwezelle zomzimba isikhathi esingafika ku-24 amahora, kunciphisa ukuzivikela komzimba okususa isifo. Lona loluhlobo lolucwaningo lubonisa ukuthi ukuphuza njalo noma kakhulu konakalisa zonke izigaba zokuphulukiswa kwesilonda nokulungiswa kwezicubu, futhi kuhambisana nokuhlala isikhathi eside esibhedlela kanye nezinga eliphezulu lezifo ngemuva kokulimala.

Lokhu kushintsha ukunquma. Isizathu sokuthatha izinyathelo zokuphepha ukugula kwe-sinus noma i-cellulitis oyelashwayo, hhayi iphilisi olithathayo. Ingilazi yewayini eyodwa emshadisweni ayiyona into efanayo nemizuliswa emine ngoMgqibelo ebusuku ngenkathi umzimba wakho uzama ukuzikhusela, futhi iseluleko esiqotho siyahlukahluka phakathi kwazo.

Ngenkathi usengumelaphi, uhlelo lokusebenza lomngane wezempilo olufana ne-August AI lungakusiza ukuthi urekhode indlela izimpawu zakho ezithuthukayo usuku nosuku, ukuze ukubambezeleka ekululameni kwakho kubonakale kusenesikhathi kunokuba naseviki lesibili.

Ucacela ucabanga nge-metronidazole, i-antibiotic engakwazi ukuhlanganiswa

Ukuhlangana kwe-amoxicillin ne-alcohol abantu abakwesaba kuyiqiniso, kodwa kungokomunye umuthi. I-MedlinePlus iyala abantu abasebenzisa i-metronidazole ukuthi bagweme i-alcohol nanoma yimiphi imikhiqizo equkethe i-propylene glycol ngesikhathi sokwelashwa kanye nezinsuku ezintathu okungenani ngemuva komthamo wokugcina. Ukuhlanganisa kubanga isicanucanu, ukuhlanza, ukubamba, ikhanda elibuhlungu, ukujuluka nokuvuvukala.

Indlela yokwenza izinto ichaza ukuthi kungani i-amoxicillin ingafakiwe. I-Metronidazole ivimbela i-aldehyde dehydrogenase, ngakho-ke i-acetaldehyde evela ku-alcohol iqoqana esikhundleni sokususwa, ikhiqize ubuhlungu obufanayo i-disulfiram elibhaliwe ukukudala. I-Amoxicillin, i-penicillin, ayithinti le ndlela kunoma iyiphi idosi.

Uma umuthi wakho ungumunye umuthi ngokuphelele, ukucabanga okufanayo kuyasebenza kumuthi ngamunye. I-Cephalexin ne-alcohol ngumbuzo olandelayo abantu abaningi abanawo, futhi impendulo lapho isondelene neye-amoxicillin kuneyo-metronidazole.

Inombolo ebhodlela lakho ayibalulekile, isithako sesibili siyinto

Ungaphuza i-alcohol nge-amoxicillin 500mg? Yebo, futhi u-500 mg akuyona into ekhethekile. Ikhamera engu-250 mg, ikhamera engu-500 mg, ithebulethi engu-875 mg, izihlafuno kanye ne-liquid suspension konke kunempendulo efanayo, ngoba akukho ukuhlangana okuzokwanda esikhundleni sokuqala. Idosi ishintsha ubungako bomuthi kuwe, hhayi ukuthi i-alcohol ingahlangana nawo yini. Uma amandla eyi-ngokwakho okukhathazayo, funda kabanzi nge-idosis evamile yabantu abadala ye-amoxicillin esikhundleni salokho.

Ukwahlukanisa okubalulekile yigama elilodwa elingaphambili kulebula. Hlola ukuthi ithi i-amoxicillin noma i-amoxicillin-clavulanate, ethengiswa njenge-Augmentin. I-LiverTox database ye-NIH ichaza i-amoxicillin-clavulanate njengesizathu esivame kakhulu sokulimala kwesibindi okubangelwa yimithi okubonakala kalula e-United States naseYurophu, cishe ezinganeni eziyi-1 kuya kwezi-2,000 zokwelashwa. I-ilebula ye-FDA ye-Augmentin iyala abalaphi ukuthi bayeke umuthi uma ukuphazamiseka kwesibindi noma i-cholestatic jaundice kuvela, futhi iyaphawula ukuthi ingavela ngesikhathi sokwelashwa noma amasonto ambalwa ngemuva kokuphela kwayo.

Qonda kahle ukuthi lokho kuyinto futhi akuyona. Kuyisici somuthi, hhayi ukuhlangana okufakazelwe kwe-alcohol-clavulanate, futhi akekho ongakubonisa ukuthi ukuphuza kukhuphula leyo ngozi eyi-1 kuya kwezi-2,000. Kuyinto nje kuphela isonto elibi ukuthi ucele isibindi sakho ukuthi sisebenze i-antibiotic eyaziwa nge-hepatotoxic kanye nokuphuza kakhulu ngesikhathi esifanayo.

Akukho isikhathi sokulinda esiyisibopho ngemuva komthamo wakho wokugcina

Bangakanani isikhathi ngemuva kwe-amoxicillin lapho ungaphunga i-alcohol? Akukho sikhathi sokulinda ngokwezindaba zemithi, ngoba akukho okumele kulindwe. Umthetho wezinsuku ezintathu we-metronidazole ngemuva komthamo wangempela. Ileba ye-Amoxicillin ayinawo okulingana, futhi ukuyidala akwenzi ukwelashwa kuphephe.

Nasi isikhathi okungenzeka ukuthi amakhasi amaningi angakutshelisi: iseluleko esibhalwe kabanzi sokulinda amahora angama-48 kuye kwangama-72 ngemuva kwekhamera yakho yokugcina asifakwanga emithonjeni ekushicilelayo. Kuyisiphakamiso sokululama esijwayelekile esethulwe ngolimi olubonakalayo lwesiphakamiso sokuphepha komuthi, futhi lezi zinto ezimbili azifani.

Sebenzisa umthetho ongawusebenzisa ngempela. Qonda lokhu ngokuthi uzizwa kanjani, hhayi ngamahora kusukela kumthamo wokugcina: umkhuhlane udlula, udla futhi uphuza ngokujwayelekile, izimpawu zicacile ukuthi ziyalulama kunokuba zihlezi. Uma kucatshangelwa ukuthi ubusuku obunzima bunganciphisa ukuxhumana komzimba isikhathi esingafika ku-24 amahora, impendulo enengqondo yokuthi singakanani isikhathi ngemuva kwe-amoxicillin lapho ungaphunga i-alcohol ukuthi kuze kube yilapho ululama ngempela, noma ngabe lokho kudinga ngaphambi kokuphela kokwelashwa noma ngeviki ngemuva kwayo.

I-Alcohol ayiyona into ethumela abantu emgqeni wokunakekelwa okungaphuthukisiwe nge-amoxicillin

Ungaphuza i-amoxicillin ngaphandle kokuthi ugibele igumbi lezimo eziphuthumayo? Yebo, futhi izimpawu ezidinga ukunakekelwa ngokushesha azihlangene nokuthi uphuze ini. Ukusabela komzimba ku-amoxicillin kungenzeka noma ngabe uphuze noma cha, futhi i-alcohol ayikubangi. Phatha okulandelayo njengezinto ezizimele engilazini yakho.

Shayela ku-911 noma uye egumbini lezimo eziphuthumayo manje uma:

• Une-swelling ubuso, izindebe, ulimi noma umphimbo, noma ubunzima bokuphefumula noma bokugwinya. Lokhu yi-anaphylaxis.
• Kubonakala isifo esibanzi esine-blistering noma isikhumba esikhwemekayo.
• Uthola uhudo olubi kakhulu noma olunegazi olunezimpawu zomkhuhlane nokubamba ngesikhathi noma ngemuva kokwelashwa, okungabonisa i-C. difficile colitis.
• Isikhumba sakho noma amehlo kuphuzi, umchamo wakho ube mnyama, noma unezinhlungu ezimbi esiswini, konke lokhu kuyizimpawu zokulimala kwesibindi futhi kuyinto okufanele kucatshangelwe kakhulu ku-Augmentin.

Bhuka ukuvakashela kungakapheli isonto elilandelayo uma:

• Izimpawu zakho azithuthuki ngemuva kwamahora angama-48 kuye kwangama-72 usebenzisa i-antibiotic.
• Uthola isifo esingesihle ngaphandle kokuvuvukala noma ubunzima bokuphefumula.
• Isicanucanu noma uhudo kwenza kube nzima ukuqedela ukwelashwa.

Khuluma nomelaphi ngaphambi kokuthi uqale uma:

• Unesifo sesibindi sanoma yiluphi uhlobo.
• Uphinde usebenzise i-metronidazole, i-tinidazole noma i-Bactrim.
• Ukhulelwe.
• Uphuza nsuku zonke noma kakhulu.
• Ubekelwe i-amoxicillin-clavulanate esikhundleni se-amoxicillin nje.

Uma ungavamile ukuthi yikuphi kulawa magaba ongawona, i-August AI Symptom Checker yamahhala ingakusiza uhlukanise phakathi kokubalulekile nokujwayelekile ngaphambi kokuthi unqume ukuthi uzoshayela noma cha.

Imibuzo ejwayelekile

Ngingiphuze kakade futhi ngabe sengikhumbula ukuthi ngisebenzisa i-amoxicillin. Ngidinga ukwenza lutho?

Cha. Akukho lutho okudingeka ukuthi lwenziwe, futhi akukho lutho oluzokwenzeka. Ngoba ungaphunga i-alcohol ngenkathi usebenzisa i-amoxicillin ngaphandle kokuhlangana kwebhicimshini, ukuphuza owakwenza ngaphambi kokukhumbula umuthi wakho akuyona into enkulu. Ungazishele noma uphinda umthamo wakho olandelayo ukuze ubuyisele. Yithathe ngokuhlela, phuza amanzi, futhi uqedele ukwelashwa njengoba kunqunyiwe.

Ngabe i-alcohol iyayiyeka i-amoxicillin ukuthi imuncwe kahle?

Cha. Uzobona isimangalo sokuthi i-alcohol yehlisa ukumuncwa kwe-amoxicillin iphindwe kwamanye ama-site ezempilo amakhulu, njalo ngaphandle kokubhekisela, umthelela wesayizi, noma isitatimende sokubaluleka kokwelashwa. Ukumuncwa okuhamba kancane akufanele kube ukuncipha kokumuncwa, futhi akukho lutho kulebula ye-FDA noma imininingwane yomsebenzisi we-NIH okuyikhombisa. Yiphatha njenge engazange iqinisekiswe futhi ingabalulekile kakhulu.

Ngabe kubalulekile ukuthi ngiphuze ibhiya, iwayini noma utshwala, futhi ingakanani eningi kakhulu?

Cha. I-Ethanol yi-ethanol, futhi isiphuzo esijwayelekile e-United States kusho amabhodlela ayi-12 obhiya obujwayelekile, amagela ayi-5 ewayini noma amagela ayi-1.5 otshwala. Abantu bavame ukubuza ngokukhethekile ukuthi ungaphunga i-alcohol nge-amoxicillin 500mg, njengokungathi inombolo iyashintsha izibalo. Ayikwenzi lokho. Isilinganiso esisebenzayo siyisilinganiso esijwayelekile sokuphuza ngokulinganisela: ukuya kuphuzo olulodwa ngosuku kwabesifazane, amabili kubashayeli.

Ngingakwazi ukuthatha umthamo wami we-amoxicillin uma nginemagundane?

Yebo. Yithathe. I-hangover yi-dehydration nokuvuvukala, hhayi ukuphikisana, futhi ukweqa imithamo yikona kuphela okubhubhisa ngempela ukwelashwa kwe-antibiotic. Uma isicanucanu siyisithiyo, thatha ikhamera ngokudla namanzi. Uma ungakwazi ukugcina imithamo isikhathi esingaphezu kosuku, shayela umelaphi wakho esikhundleni sokuyeka ukwelashwa ngasese.

Ngabe kuphephile ukuphuza i-alcohol nge-amoxicillin ngesikhathi sokukhulelwa?

Cha, yize isizathu singahlangene ne-antibiotic. Akukho ubungako obuphephile be-alcohol obubekwe nganoma yisiphi isikhathi sokukhulelwa, ngakho-ke impendulo izofana nokuba nomuthi noma cha. Uma ukhulelwe futhi ubekelwe noma iyiphi i-antibiotic, qinisekisa ukukhetha nodokotela wakho wokubeletha, ikakhulukazi uma kuyi-amoxicillin-clavulanate.

Isiphetho

I-Amoxicillin ne-alcohol akuhlangani, ngakho-ke ukuphuza ngeke kukwenze konakale noma kunciphise umuthi. Okuzokwenza ukuthi kuzohamba kancane ukululama ozama ukusheshisa, okuyikho kuphela ukubuyela emuva okunye okusinda ekuxhumaneni nobufakazi. Izimo ezimbili zangempela ziyikho ukuphuza kakhulu ku-amoxicillin-clavulanate, lapho uhlanganisa khona izinto ezimbili ezibeka isibindi engcupheni, nokudlula umuthi wakho njenge-metronidazole, ongempela ohlangana ngempela.

Qedela yonke imithamo noma ngabe uphuza ini. Uma umbuzo wakho wangempela uphathelene neminye imithi kunokuba nge-alcohol, funda kabanzi nge-ukuhlangana kwe-amoxicillin okubalulekile ukwazi, futhi uhlelo lokusebenza lomngane wezempilo olufana ne-August AI lungakusiza urekhode izimpawu futhi ubuze imibuzo eyengeziwe phakathi kokuqokwa.

Ukwenqaba: Lesi sihloko siyizinhloso zokwazisa kuphela futhi asisho iseluleko sezokwelapha. Njalo xhumana nomhlinzeki wezempilo onekhono ngezinqumo zokuxilonga nokwelashwa. Uma ubhekene nesimo esiphuthumayo sezokwelapha, shayela ku-911 noma uye egumbini lezimo eziphuthumayo eliseduze ngokushesha.