Yini i-Acetylcysteine (Indlela ye-Intravenous): Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Acetylcysteine enikezwa nge-IV iyimithi esindisa impilo esebenza njenge-antidote ebuthini be-acetaminophen (Tylenol). Lapho umuntu ethatha i-acetaminophen eningi kakhulu, le mithi ingavimbela ukulimala okukhulu kwesibindi ngokusiza umzimba wakho ukuthi uqhubeke nokwakheka okunobuthi ngokuphepha.

Lokhu kwelashwa okunamandla kusebenza ngokugcwalisa kabusha into ebalulekile esibindini sakho ebizwa ngokuthi i-glutathione, evame ukuvikela amaseli esibindi sakho ekulimaleni. Cabanga ngakho njengokunikeza isibindi sakho amathuluzi esiwadingayo ukulwa nemiphumela eyingozi ye-acetaminophen overdose.

Yini i-Acetylcysteine?

I-Acetylcysteine iyimithi equkethe i-N-acetylcysteine, uhlobo oluguquliwe lwe-amino acid cysteine. Yaziwa kakhulu njengokwelashwa okujwayelekile kwe-acetaminophen overdose, lapho ingasindisa ngokoqobo izimpilo uma inikezwa ngokushesha.

Ifomu le-intravenous lisho ukuthi linikezwa ngqo emgudwini wakho wegazi ngomthambo, okuyivumela ukuthi isebenze ngokushesha emzimbeni wakho wonke. Le ndlela yokulethwa ngokuqondile iqinisekisa ukuthi imithi ifinyelela esibindini sakho ngokushesha ngangokunokwenzeka, okubalulekile lapho welapha ubuthi.

Abahlinzeki bezempilo babheka le mithi njengabaluleke kakhulu ebuthini be-acetaminophen kangangokuthi igcinwa itholakala kalula eminyangweni yezimo eziphuthumayo emhlabeni wonke. Ngokushesha inikezwa ngemuva kwe-overdose, kulapho isebenza kangcono khona ukuvikela isibindi sakho.

Isetshenziselwani i-Acetylcysteine?

Ukusetshenziswa okuyinhloko kwe-IV acetylcysteine ukwelapha ubuthi be-acetaminophen, kungakhathaliseki ukuthi i-overdose yayingamabomu noma yayingahlosiwe. Yilokhu okubizwa ngokuthi i-antidote ekhona engavimbela ukulimala okukhulu kwesibindi futhi okungenzeka ukuthi isindise impilo yakho.

Le mithi ngezinye izikhathi isetshenziselwa ezinye izimo lapho umzimba wakho udinga ukwesekwa okwengeziwe kwe-antioxidant. Abanye odokotela bayayisebenzisa ukusiza ukuvikela izinso ngesikhathi senqubo ethile yezokwelapha engase ibangele ukulimala kwezinso, nakuba lokhu kusetshenziswa kungavamile.

Ezimweni ezingavamile, abahlinzeki bezempilo bangasebenzisa i-acetylcysteine ukusiza ngezinye izinhlobo zobuthi noma ukusekela ukusebenza kwesibindi ezimweni ezithile zezokwelapha. Nokho, lezi zindlela zokusebenzisa zivame ukugcinelwa izimo zezokwelapha ezikhethekile futhi zidinga ukuqapha ngokucophelela.

Isebenza Kanjani I-Acetylcysteine?

I-Acetylcysteine isebenza ngokuthuthukisa uhlelo lwakho lwemvelo lokuzivikela esibindini ezintweni ezinobuthi. Uma uthatha i-acetaminophen eningi kakhulu, isibindi sakho sikhiqiza into eyingozi ebizwa nge-NAPQI engabhubhisa amaseli esibindi.

Lo muthi unikeza isibindi sakho izinto ezidingekayo ukwenza i-glutathione, i-antioxidant enamandla eqeda i-NAPQI. Cabanga nge-glutathione njengendlovu yakho yemvelo yesibindi, futhi i-acetylcysteine njengento edingekayo ukulungisa nokuqinisa leyo ndlovu.

Lo muthi uthathwa njengosebenza kahle kakhulu kunokuba buthaka, ikakhulukazi uma unikezwa phakathi kwamahora okuqala angu-8-10 ngemva kokweqisa kwe-acetaminophen. Ngemva kwalesi sikhathi esibucayi, kungase kusize, kodwa ukuvikelwa akuphelele kangako, yingakho isikhathi sibaluleke kangaka.

Kufanele Ngiyithathe Kanjani I-Acetylcysteine?

Ngeke uzithathele wena lo muthi - ngaso sonke isikhathi unikezwa ochwepheshe bezempilo esibhedlela noma endaweni yomtholampilo. Ifomu le-IV lixutshwa nesixazululo esingenazo izinto ezingcolile futhi linikezwe ngenaliti efakwe emthanjeni wakho.

Ukwelashwa ngokuvamile kuhilela imithamo eminingi enikezwa emahoreni angu-20-21, kulandela isimiso esithile esizolawulwa ithimba lakho lezokwelapha. Akudingeki ukhathazeke ngokudla noma ukuphuza imikhawulo ngesikhathi sokwelashwa, njengoba umuthi ungena ngqo egazini lakho.

Ithimba lakho lezempilo lizokuqapha eduze ngesikhathi sokwelashwa, lihlole amazinga egazi lakho futhi libuke noma yiziphi izindlela zokuphendula. Ukusetha kwe-IV kubavumela ukuthi balungise umthamo noma bayeke ukwelashwa ngokushesha uma kudingeka.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Acetylcysteine?

Ukwelashwa okuvamile kokuhlaselwa ubuthi yi-acetaminophen kuthatha cishe amahora angu-20-21 esewonke, okuhlinzekwa ngezigaba ezintathu ngemithamo encishayo. Lena akuyona imithi oyithatha izinsuku noma amasonto - ukwelashwa okujulile, okukhawulelwe isikhathi.

Udokotela wakho uzoqapha amazinga egazi lakho ngesikhathi sokwelashwa ukuze anqume ukuthi ngabe udinga inkambo ephelele noma ngabe ukwelashwa kungamiswa ngaphambi kwesikhathi. Abanye abantu abanamazinga aphansi okweqisa umthamo bangase baqede ukwelashwa ngokushesha, kanti abanye bangase badinge ukwelashwa okweluliwe.

Isinqumo sokuqhubeka noma ukumisa ukwelashwa sincike ezintweni eziningi ezihlanganisa amazinga egazi lakho le-acetaminophen, izivivinyo zomsebenzi wesibindi, nokuthi usabela kanjani emuthini. Ithimba lakho lezokwelapha lizothatha lezi zinqumo ngokusekelwe esimweni sakho esithile.

Yiziphi Imiphumela Eceleni ye-Acetylcysteine?

Abantu abaningi bayayibekezelela kahle i-IV acetylcysteine, kodwa eminye imiphumela emibi ingenzeka ngesikhathi sokwelashwa. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi uzizwe ulungiswe kangcono futhi ungakhathazeki ngesikhathi sokwelashwa kwakho.

Imiphumela emibi ejwayelekile abantu abaningi abayitholayo ihlanganisa:

• Isicanucanu nokuhlanza, okungalawulwa ngemithi elwa nesicanucanu
• Ukubomvu noma ukubomvu kwesikhumba, ikakhulukazi ebusweni nasentanyeni yakho
• Ukuqubuka kwesikhumba okuncane noma ukuluma
• Ikhanda elivame ukuzixazulula ngokwalo
• Isiyezi noma ukuzwa ukukhathala

Lezi zindlela ezivamile zivame ukuba mnene futhi zesikhashana. Ithimba lakho lezempilo linganikeza imithi ukusiza ukulawula isicanucanu noma ezinye izimpawu ezingakhululekile ngenkathi uqhubeka nokwelashwa.

Imiphumela emibi engathi sína kodwa engavamile ingahlanganisa:

• Ukungezwani komzimba okukhulu okunezinkinga zokuphefumula noma ukuvuvukala
• Ushintsho olukhulu emfuthe yegazi noma izinga lokushaya kwenhliziyo
• Ukuphendula kwesikhumba okukhulu noma ukuqubuka okusabalale
• Ubunzima bokuphefumula noma ukuqina kwesifuba
• Isicanucanu esibi nokuhlanza okuvimbela ukugcina uketshezi phansi

Nakuba lezi zimo ezinzima zingavamile, ithimba lakho lezokwelapha likuqapha ngokuqhubekayo futhi lingazelapha ngokushesha uma zenzeka. Izinzuzo zokuvimbela ukulimala kwesibindi ngokuvamile zidlula lezi zingozi.

Ubani Ongafanele Athole I-Acetylcysteine?

Bambalwa kakhulu abantu abangakwazi ukuthola i-IV acetylcysteine uma idingeka ekuphuzeni i-acetaminophen. Umuthi uthathwa njengokwelashwa okubalulekile, futhi odokotela bazosebenza ngaphandle kwezimo eziningi zempilo ukuze baqinisekise ukuthi ungayithola ngokuphepha.

Abantu abanesifuba esikhulu bangase badinge ukuqashwa okwengeziwe ngesikhathi sokwelashwa, njengoba umuthi ngezinye izikhathi ungenza kube nzima ukuphefumula. Kodwa-ke, lokhu ngokuvamile akuvimbeli ukwelashwa - kusho nje ukubuka okucophelelayo.

Uma wazi ukuthi unokungezwani komzimba okukhulu ne-acetylcysteine, odokotela bakho bazohlola izingozi nezinzuzo ngokucophelela. Bangase banikeze umuthi ngokuqapha okwengeziwe nemithi yokuvimbela ukungezwani komzimba, njengoba ukuphuzwa kwe-acetaminophen okungelashwanga kungaba yingozi empilweni.

Amagama Omkhiqizo we-Acetylcysteine

Igama elivamile lomkhiqizo we-IV acetylcysteine yi-Acetadote, esetshenziswa kakhulu ezibhedlela kulo lonke elase-United States. Lena yindlela ekhethekile eyenzelwe ukusetshenziswa ngemithambo yegazi ekwelapheni ukuphuzwa kwe-acetaminophen.

Ezinye izibhedlela zingase zisebenzise ezinye izinhlobo noma izinguqulo ezivamile zomuthi, kodwa zonke ziqukethe isithako esifanayo esisebenzayo futhi zisebenza ngendlela efanayo. Into ebalulekile ukuthola ukwelashwa ngokushesha, kungakhathaliseki igama lomkhiqizo elithile.

Ithimba lakho lezempilo lizosebenzisa noma iyiphi ifomula etholakalayo esikhungweni sabo, njengoba zonke izinguqulo ezivunyelwe zisebenza ngokulinganayo ekwelapheni ukweqisa kwe-acetaminophen.

Ezinye Izindlela ze-Acetylcysteine

Azikho ezinye izindlela ezisebenzayo ze-acetylcysteine zokwelapha ukuphuzwa kwe-acetaminophen. Lo muthi uyindinganiso yegolide kanye ne-antidote kuphela efakazelwe ukweqisa kwe-acetaminophen.

Nakuba imithi ethile yokuhlola iye yahlolwa, akukho neyodwa ebonakale isebenza njenge-acetylcysteine. Ezinye izindlela zokwelapha ezisekelayo njengokufakelwa kwesibindi zingase zicatshangelwe ezimweni ezinzima, kodwa lezi ziyizindlela zokugcina uma ukwelashwa nge-acetylcysteine kungaphumelelanga.

Okubalulekile ukuthola i-acetylcysteine ngokushesha ngangokunokwenzeka ngemuva kokweqisa kwe-acetaminophen, njengoba akukho omunye umuthi onganikeza izinga elifanayo lokuvikela isibindi.

Ingabe i-Acetylcysteine Ingcono Kunezinye Izindlela Zokwelapha?

I-Acetylcysteine ithathwa njengendlela yokwelapha eqinisekile yobuthi be-acetaminophen, ngaphandle komunye umuthi osondela ekusebenzeni kwayo. Akuyona indaba yokuthi

Akudingeki ukhathazeke ngokuthola i-acetylcysteine ​​eningi ngengozi, njengoba ochwepheshe bezempilo bebala ngokucophelela futhi baqaphe yonke imithamo. Umuthi unikezwa nge-IV infusion elawulwayo, okwenza ukweqisa ngengozi kungenzeki.

Uma ukhathazekile ngemithi yakho noma uba nezimpawu ezingavamile, tshela ithimba lakho lezempilo ngokushesha. Bangashintsha ukwelashwa kwakho futhi bakuqaphe eduze uma kudingeka.

Kwenziwani Uma Ngiphuthelwa Umthamo We-Acetylcysteine?

Ukuphuthelwa umthamo akuyona into okudingeka ukhathazeke ngayo, njengoba ochwepheshe bezempilo bephatha lonke uhlelo lwakho lokwelashwa. Umuthi unikezwa ngokuqhubekayo nge-IV yakho, ngakho-ke akukho ngozi yokuthi uphuthelwe imithamo.

Uma kukhona ukuphazamiseka ekwelashweni kwakho nganoma yisiphi isizathu, ithimba lakho lezokwelapha lizolungisa isikhathi kanye nokulinganisa ukuze liqinisekise ukuthi usathola inzuzo ephelele yokuvikela yomuthi.

Kungenzeka Nini Ukumisa Ukwelashwa Nge-Acetylcysteine?

Ukwelashwa ngokuvamile kuqhubeka isikhathi esiphelele sama-20-21 amahora, kodwa udokotela wakho angase akuyeke ngaphambi kwesikhathi uma izivivinyo zakho zegazi zikhombisa ukuthi umzimba wakho usususe i-acetaminophen futhi umsebenzi wesibindi sakho ujwayelekile. Lesi sinqumo senziwa njalo yithimba lakho lezempilo ngokusekelwe emiphumeleni yelabhorethri.

Abanye abantu badinga ukwelashwa okweluliwe ngaphezu kwenkambo ejwayelekile uma amazinga abo e-acetaminophen esahlala ephezulu noma uma bekhombisa izimpawu zomonakalo wesibindi. Ithimba lakho lezokwelapha lizoqhubeka nokuqapha futhi lilungise ukwelashwa njengoba kudingeka.

Ngingashayela Noma Ngisebenze Ngemva Kokwelashwa Nge-Acetylcysteine?

Kufanele ugweme ukushayela noma ukusebenzisa imishini okungenani amahora angama-24 ngemva kokuqeda ukwelashwa nge-acetylcysteine, njengoba ungase uzizwe unesiyezi noma unesiyezi. Umuthi ungase ubangele imiphumela emibi yesikhashana engase ithinte ikhono lakho lokugxila noma ukusabela ngokushesha.

Abantu abaningi bazizwa bejwayelekile phakathi nosuku olulodwa noma ezimbili ngemva kokwelashwa, kodwa lalela umzimba wakho futhi ungaphuthumi emuva emisebenzini efunayo. Udokotela wakho uzokunikeza imihlahlandlela ethile mayelana nokuthi kuphephile nini ukuqala kabusha imisebenzi ejwayelekile ngokuya ngokuthi uzizwa kanjani.