Yini i-Amiodarone (Indlela yokujova ngomthambo): Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Amiodarone iyikhambi elinamandla lokushaya kwenhliziyo elisetshenziswa odokotela ukwelapha ukushaya kwenhliziyo okungajwayelekile okuyingozi, okusongela impilo. Uma inikezwa nge-IV (indlela yokujova ngomthambo), isebenza ngokushesha ukusiza ukubuyisela ukushaya kwenhliziyo yakho okuvamile nokuvimbela ama-arrhythmias ayingozi angabulala.

Lo muthi ungowesigaba esibizwa ngokuthi ama-antiarrhythmics, okusho ukuthi usiza ukulawula ukuthi amasignali kagesi ahamba kanjani ngenhliziyo yakho. Cabanga ngayo njengomlawuli wethrafikhi wesistimu kagesi yenhliziyo yakho, eqinisekisa ukuthi konke kuhamba kahle futhi kuphephile.

Yini i-Amiodarone?

I-Amiodarone iyikhambi elinikezwa ngudokotela elilawula umsebenzi kagesi wenhliziyo yakho. Ngenye yemithi esebenza kahle kakhulu etholakalayo yokwelapha izinkinga ezinkulu zokushaya kwenhliziyo, ikakhulukazi lezo ezingasabeli kwezinye izindlela zokwelapha.

Uma inikezwa ngomthambo, i-amiodarone ingena ngqo emgudwini wakho wegazi, okuyivumela ukuthi isebenze ngokushesha kakhulu kunezinhlobo zomlomo. Lokhu kuyenza ibaluleke kakhulu ezimweni eziphuthumayo lapho ukushaya kwenhliziyo yakho kudinga ukulungiswa ngokushesha.

Lo muthi usetshenziswe ngokuphepha amashumi eminyaka futhi uthathwa njengokwelashwa okuyisisekelo kwama-arrhythmias asongela impilo. Ithimba lakho lezokwelapha lizokuqapha eduze ngenkathi uthola lo muthi ukuze liqinisekise ukuthi usebenza ngempumelelo.

Isetshenziselwani i-Amiodarone?

I-Amiodarone IV isetshenziswa ikakhulukazi ukwelapha izifo ezinzima, ezisongela impilo zokushaya kwenhliziyo ezidinga ukunakwa ngokushesha. Udokotela wakho ngokuvamile uzogcina lo muthi ezimweni ezinzima lapho ezinye izindlela zokwelapha zingasebenzanga noma zingafaneleki.

Izimo eziyinhloko eziphathwayo zihlanganisa i-ventricular fibrillation, ebangela ukuthi amagumbi aphansi enhliziyo yakho athuthume esikhundleni sokumpompa igazi ngempumelelo. Iphinde isetshenziswe nge-ventricular tachycardia, lapho inhliziyo yakho ishaya ngokushesha okuyingozi futhi ayikwazi ukugcwala ngegazi ngendlela efanele phakathi kokushaya.

Ngaphezu kwalokho, odokotela basebenzisa i-amiodarone ngenxa ye-atrial fibrillation ebangela izimpawu ezinzima noma izinkinga. Lokhu kwenzeka lapho amagumbi akho angaphezulu enhliziyo eshaya ngokungajwayelekile, okungenzeka kuholele ezigulini zegazi noma ezinye izinkinga ezinzima.

Ngezinye izikhathi, umhlinzeki wakho wokunakekelwa kwezempilo angase asebenzise i-amiodarone ukuvimbela ama-arrhythmias ngesikhathi sezinqubo ezithile zenhliziyo noma ukuhlinzwa. Umuthi usiza ukugcina isigqi senhliziyo yakho sizinzile ngalezi zikhathi ezibucayi.

Isebenza Kanjani I-Amiodarone?

I-Amiodarone isebenza ngokuvimba izindlela eziningi zikagesi emsipheni wakho wenhliziyo. Ithathwa njengomuthi oqinile kakhulu we-antiarrhythmic ngoba ithinta iziteshi eziningana ezihlukene ze-ion ezilawula umsebenzi kagesi wenhliziyo yakho.

Inhliziyo yakho ishaya ngenxa yezimpawu zikagesi ezihamba ngezindlela ezikhethekile. Uma lezi zimpawu ziba nezinxushunxushu noma zilandela izindlela ezingajwayelekile, ama-arrhythmias ayingozi angase avelaphe. I-Amiodarone isiza ukubuyisela ukuhleleka kulolu hlelo lukagesi.

Umuthi wehlisa ukuhamba kukagesi enhliziyweni yakho futhi wenza ukuthi imisipha yenhliziyo ingasabeli ezimpawini zikagesi ezingajwayelekile. Lokhu kunika inhliziyo yakho isikhathi sokusetha kabusha isigqi sayo bese ibuyela endleleni ejwayelekile.

Ngenxa yokuthi i-amiodarone inamandla kangaka, ingasebenza ngisho nalapho eminye imithi yesigqi senhliziyo ihlulekile. Kodwa-ke, lawa mandla asho ukuthi idinga ukuqapha ngokucophelela nokuqondiswa kwezokwelapha okune-skill.

Kufanele Ngiyithathe Kanjani I-Amiodarone?

I-Amiodarone IV ihlale inikezwa ochwepheshe bezempilo esibhedlela noma endaweni yomtholampilo. Ngeke uziphakele lo muthi wena uqobo - abasebenzi bezokwelapha abaqeqeshiwe bazosingatha zonke izici zokwelashwa kwakho.

Umuthi uvame ukunikezwa ngomugqa we-IV ophakathi noma umthambo omkhulu ongaphansi ngoba ungacasula imithambo yegazi emincane. Ithimba lakho lokunakekelwa kwezempilo lizobala ngokucophelela umthamo wakho ngokusekelwe esisindweni sakho, isimo sezokwelapha, nokuthi inhliziyo yakho isabela kanjani.

Ngesikhathi sokwelashwa, uzoxhunywa emishinini eqhubekayo yokubheka inhliziyo. Lokhu kuvumela ithimba lakho lezokwelapha ukuthi libuke ukuthi isigqi senhliziyo yakho sishintsha kanjani futhi lilungise ukwelashwa kwakho njengoba kudingeka. Ama-monitor azolandela izinga lenhliziyo yakho, isigqi, nomfutho wegazi ngesikhathi sokufakwa.

Akudingeki ukhathazeke ngesikhathi sokudla noma eminye imithi - ithimba lakho lezempilo lizoxhumanisa konke ngawe. Bazophinda baqinisekise ukuthi ubekwe kahle futhi unakho konke okudingayo ngesikhathi sokwelashwa.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Amiodarone?

Ubude bokwelashwa nge-IV amiodarone buhlukahluka kakhulu kuye ngesimo sakho esithile nokuthi usabela kanjani emuthini. Abanye abantu bayayidinga amahora ambalwa nje, kanti abanye bangase badinge izinsuku eziningana zokwelashwa.

Udokotela wakho uzoqhubeka nokuhlola isigqi senhliziyo yakho kanye nesimo esiphelele ukuze anqume ukuthi udinga isikhathi esingakanani umuthi we-IV. Uma isigqi senhliziyo yakho sizinzile futhi siba esibikezelekayo, bangase bakushintshele ku-oral amiodarone noma omunye umuthi.

Ezimweni eziphuthumayo, ungase uthole i-amiodarone kuze kube yilapho isigqi senhliziyo yakho sibuyela kokujwayelekile futhi sihlala sizinzile. Ngezinkinga eziqhubekayo zesigqi, udokotela wakho angase asebenzise ifomu le-IV njengebhuloho ngenkathi enquma uhlelo olungcono lokwelashwa kwesikhathi eside.

Isinqumo sokuyeka i-IV amiodarone sincike ezintweni eziningana, okuhlanganisa ukuthi inhliziyo yakho isabela kanjani, ukuthi ngabe uthola yiziphi izinto ezingezinhle, nokuthi isimo senhliziyo yakho esingaphansi sidingani ukuze kuqhubeke ukuphathwa.

Yiziphi Izinto Ezingezinhle Ze-Amiodarone?

Njengayo yonke imithi enamandla, i-amiodarone ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle uma isetshenziswa ngendlela efanele. Ithimba lakho lezempilo lizokubheka eduze nganoma yiziphi izimpawu zezinkinga ngesikhathi sokwelashwa kwakho.

Ake sibheke imiphumela emibi evame kakhulu ongase uyithole, sikhumbula ukuthi iningi liyaphathwa ngokunakekelwa kwezokwelapha okufanele:

• Umfutho wegazi ophansi, ongase ukwenze uzizwe unesiyezi noma unomuzwa wokukhathala
• Ukushaya kwenhliziyo okuhamba kancane kunokujwayelekile, okuzoqashwa udokotela wakho ngokucophelela
• Isicanucanu noma isisu esibuhlungu, ngokuvamile esingathí sina futhi sesikhashana
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile
• Ukuqubuka endaweni ye-IV, okuhlanganisa ububomvu noma ukungakhululeki
• Ushintsho ekuhlolweni komsebenzi wesibindi, okuqashwa ngomsebenzi wegazi

Le miphumela ejwayelekile ivame ukuba yesikhashana futhi ivame ukuthuthuka njengoba umzimba wakho uzivumela emuthini noma njengoba umthamo uguqulwa.

Manje, ake sixoxe ngemiphumela emibi engavamile kodwa ebucayi edinga ukunakekelwa kwezempilo ngokushesha, nakuba lokhu kwenzeka kaningi:

• Ukungezwani komzimba okukhulu okunzima ukuthatha umoya, ukuvuvukala, noma ukuqubuka
• Ushintsho olukhulu emsebenzini we-thyroid, oluthinta imetabolism yakho
• Ukuvuvukala kwamaphaphu noma ukulimala, okungase kuvele ngokusetshenziswa isikhathi eside
• Izinkinga ezinkulu zesibindi, nakuba lokhu kungavamile ngokusetshenziswa kwe-IV yesikhashana
• Ushintsho embonweni noma ukuzwela ekukhanyeni
• Ukushintsha kombala wesikhumba, ngokuvamile ngokusetshenziswa isikhathi eside

Ithimba lakho lezempilo liqeqeshwe ukubona lezi zinkinga ezingavamile ekuqaleni futhi lizothatha isinyathelo ngokushesha uma zenzeka. Ukusetha esibhedlela kunikeza indawo ephephe kakhulu yokuqapha nokuphatha noma yimiphi imiphumela emibi.

Ubani Ongafanele Athole i-Amiodarone?

Abanye abantu abakwazi ukuthola i-amiodarone ngokuphepha ngenxa yengozi eyengeziwe yezinkinga ezinzima. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokubhala lo muthi.

Akufanele uthole i-amiodarone uma wazi ukuthi unokungezwani komzimba emuthini noma ezithakweni zawo, okuhlanganisa i-iodine. Ngaphezu kwalokho, abantu abanezinhlobo ezithile zokuvinjwa kwenhliziyo (lapho amasignali kagesi engakwazi ukuhamba kahle enhliziyweni) ngokuvamile abakwazi ukusebenzisa lo muthi ngokuphepha.

Abantu abanezinkinga ezinzima ze-thyroid badinga ukucatshangelwa okukhethekile, njengoba i-amiodarone iqukethe i-iodine futhi ingenza izinkinga ze-thyroid zibe zimbi kakhulu. Udokotela wakho uzohlola ukusebenza kwe-thyroid yakho ngaphambi nangemva kokwelashwa.

Uma unezifo zesibindi ezinzima, umhlinzeki wakho wezempilo uzodinga ukulinganisa izinzuzo nezingozi, njengoba i-amiodarone ingathinta ukusebenza kwesibindi. Ngokufanayo, abantu abanezimo ezithile zamaphaphu bangase badinge ukwelashwa okuhlukile.

Abesifazane abakhulelwe badinga ukucatshangelwa okukhethekile, njengoba i-amiodarone ingathinta ingane esakhula. Udokotela wakho uzosebenzisa kuphela lo muthi ngesikhathi sokukhulelwa uma izinzuzo zicacile ukwedlula izingozi ezingaba khona.

Amagama Omkhiqizo we-Amiodarone

I-Amiodarone itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Cordarone iyona evame ukwaziwa kakhulu. Ungase futhi uhlangane ne-Pacerone, nakuba lokhu ngokuvamile kuyifomu lomlomo kunokuthi kube yinguqulo ye-IV.

Endaweni yasesibhedlela, uzovame ukuthola inguqulo ejwayelekile ye-amiodarone, esebenza kahle njengezinguqulo zegama lomkhiqizo. Ithimba lakho lezempilo lizosebenzisa noma iyiphi ifomu elifanele kakhulu isimo sakho.

Abakhiqizi abahlukene bangase bakhiqize i-amiodarone IV, kodwa zonke izinguqulo kumele zihlangabezane namazinga afanayo aqinile ekhwalithi nokuphepha. Usokhemisi wakho nethimba lezokwelapha bazoqinisekisa ukuthi uthola ukwakheka okulungile okudingayo.

Ezinye izindlela ze-Amiodarone

Eminye imithi eminingi ingelapha izinkinga zesigqi senhliziyo, nakuba i-amiodarone ivame ukukhethwa ezimweni ezinzima kakhulu. Udokotela wakho angase acabangele ezinye izindlela ezisuselwe esimweni sakho esithile kanye nomlando wezokwelapha.

Eminye imithi ye-antiarrhythmic ye-IV ihlanganisa i-procainamide, esebenza ngendlela ehlukile kodwa ingasebenza ezinhlotsheni ezithile zezinkinga zesigqi. I-Lidocaine ingenye inketho, ikakhulukazi kuma-ventricular arrhythmias, nakuba ngokuvamile ingasebenzi kangako kune-amiodarone.

Kwabanye abantu, i-electrical cardioversion (ama-shocks kagesi alawulwayo) ingase ibe enye indlela yokwelashwa ngemithi. Le nqubo ingasetha kabusha isigqi senhliziyo yakho ngokushesha futhi ngezinye izikhathi isetshenziswa kanye noma esikhundleni se-amiodarone.

Ezimweni ezithile, udokotela wakho angase asebenzise eminye imithi efana nama-beta-blockers noma ama-calcium channel blockers ukusiza ukulawula isigqi senhliziyo yakho, nakuba lezi zisebenza ngezindlela ezihlukile kune-amiodarone.

Ingabe i-Amiodarone Ingcono Kunezinye Imithi Yesigqi Senhliziyo?

I-Amiodarone ivame ukubhekwa njengomuthi osebenza kahle kakhulu ekwelapheni izifo zesigqi senhliziyo ezisongela impilo. Inezinga eliphezulu lempumelelo kunezinye izidakamizwa eziningi ze-antiarrhythmic, ikakhulukazi kuma-arrhythmias ayingozi kakhulu.

Nokho,

Eqinisweni, i-amiodarone ingenye yezemithi ezimbalwa ezingamelana nokushaya kwenhliziyo odokotela abazizwa bekhululekile ukuzisebenzisa kubantu abanomsebenzi wenhliziyo onciphile. Ithimba lakho lezokwelapha lizobheka umsebenzi wenhliziyo yakho ngokuqinile ngesikhathi sokwelashwa ukuze liqinisekise ukuthi uphendula kahle.

Kufanele ngenzeni uma ngizwa imiphumela emibi evela ku-Amiodarone?

Njengoba uzobe usesimweni somtholampilo lapho uthola i-IV amiodarone, ithimba lakho lezempilo lizokubheka ngokuqhubekayo imiphumela emibi. Uma uqaphela noma yiziphi izimpawu ezingavamile noma ukungakhululeki, tshela umhlengikazi wakho noma udokotela ngokushesha.

Ungazami ukukubekezelela noma ucabange ukuthi izimpawu ezincane zizonyamalala zodwa. Ngisho nezinguquko ezibonakala zincane zingabaluleka uma uthola umuthi onamandla kangaka. Ithimba lakho lezokwelapha lingathanda kakhulu ukwazi ngezinkinga ezingaba khona ekuqaleni kunokuzithola kamuva.

Ngingaba ne-Amiodarone uma ngithatha eminye imithi yenhliziyo?

I-Amiodarone ingasebenzisana neminye imithi eminingi, ngakho udokotela wakho uzobuyekeza ngokucophelela yonke imithi yakho yamanje ngaphambi kokuqala ukwelashwa. Ezinye izindlela zokuxhumana zingalawulwa ngokulungisa imithamo, kanti ezinye zingase zidinge ukushintsha imithi.

Imithi ejwayelekile esebenzisana ne-amiodarone ihlanganisa ama-blood thinners, ama-antibiotics athile, neminye imithi yenhliziyo. Ithimba lakho lezempilo lizoxhumanisa yonke imithi yakho ukuze liqinisekise ukuthi isebenza ngokuphepha ndawonye.

Isebenza ngokushesha kangakanani i-IV Amiodarone?

I-IV amiodarone ngokuvamile iqala ukusebenza phakathi nehora lokuqala lokwelashwa, nakuba umphumela ogcwele ungase uthathe amahora amaningana ukuthi ukhule. Ungase uqaphele ukuthi isigqi senhliziyo yakho siqala ukuthuthuka ngokushesha, kodwa ukuzinza okuphelele kuvame ukuthatha isikhathi eside.

Ithimba lakho lezokwelapha lizobe libukele i-monitor yakho yenhliziyo ngokuqhubekayo ukuze lilandelele ukuthi uphendula ngokushesha kangakanani nokuthi kahle kangakanani emuthini. Bangakwazi ukulungisa ukwelashwa kwakho ngokusekelwe ekutheni isigqi senhliziyo yakho sishintsha kanjani ngokuhamba kwesikhathi.

Ngizodinga ukunakekelwa okulandelayo ngemva kokwelashwa nge-IV Amiodarone?

Yebo, cishe uzodinga ukunakekelwa okuqhubekayo ngemuva kokuthola i-IV amiodarone, ngisho noma isigqi senhliziyo yakho sithuthuka kakhulu. Udokotela wakho uzofuna ukuqapha ukusebenza kwenhliziyo yakho futhi ahlole noma yimiphi imiphumela eqhubekayo yomuthi.

Ungase udinge ukuhlolwa kwegazi ukuze uhlole umsebenzi wakho wendlala yegilo nesibindi, njengoba i-amiodarone ingathinta lezi zitho ngisho nangemva kokuthi ukwelashwa kuyeka. Udokotela wakho wenhliziyo uzophinda afune ukukubona njalo ukuze aqinisekise ukuthi isigqi senhliziyo yakho sihlala sizinzile futhi axoxe nganoma yiziphi izidingo zokwelashwa zesikhathi eside.