Yini i-Amoxapine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Amoxapine iyisidakamizwa esibhalwe ngudokotela esilwa nokucindezeleka esingaphansi kwezigaba zemithi ebizwa ngokuthi ama-tricyclic antidepressants. Udokotela wakho angase akubhalele lo muthi uma ubhekene nokucindezeleka okungazange kuphendule kahle kwezinye izindlela zokwelapha. Nakuba ngokuvamile kungewona umuthi wokuqala wokwelapha ukucindezeleka namuhla, i-amoxapine ingasebenza kahle kubantu abathile uma imithi emisha ingazange inikeze impumuzo oyidingayo.

Yini i-Amoxapine?

I-Amoxapine iyi-tricyclic antidepressant esebenza ngendlela ehlukile kuma-antidepressants amaningi anamuhla ongase uzwile ngawo. Yathuthukiswa ngeminyaka yawo-1960 futhi isisize abantu ukuthi balawule ukucindezeleka amashumi eminyaka. Lo muthi uhlukile ngoba futhi unezinto ezingasiza ngokuphatheka kabi kanye nezinhlobo ezithile zezimpawu ze-psychotic.

Ngokungafani nama-antidepressants amasha afana nama-SSRI, i-amoxapine ithinta amakhemikhali obuchopho amaningi ngesikhathi esisodwa. Le ndlela ebanzi ngezinye izikhathi ingasebenza kahle kubantu abangazange bathole impumuzo ngeminye imithi. Udokotela wakho uzocabangela isimo sakho esithile kanye nomlando wezokwelapha ngaphambi kokuncoma le ndlela yokwelapha.

Isetshenziselwani i-Amoxapine?

I-Amoxapine ngokuyinhloko ibhalelwe ukwelapha i-major depressive disorder, ikakhulukazi uma ezinye izidakamizwa ezilwa nokucindezeleka zingasebenzanga kahle kuwe. Udokotela wakho angase akhethe lo muthi uma uhlangabezana nezimpawu zokucindezeleka ezinzima ezithinta kakhulu impilo yakho yansuku zonke.

Ngaphandle kokucindezeleka, odokotela ngezinye izikhathi babhala i-amoxapine kwezinye izimo. Ingasiza ekuphatheni ukukhathazeka okwenzeka kanye nokucindezeleka, futhi kwezinye izimo, ingasetshenziselwa ukwelapha izimpawu ezithile ze-psychotic. Abanye abantu bayayithola ilusizo ezimweni zobuhlungu obungapheli, nakuba lokhu kubhekwa njengokusebenzisa ngaphandle kwesilebheli.

Ake sibheke izimo ezithile i-amoxapine engasiza ngazo:

• Ukuphazamiseka okukhulu kokucindezeleka okunezici ze-melancholic
• Ukucindezeleka okunezimpawu zokukhathazeka
• Ukucindezeleka okunezici ze-psychotic
• Ukucindezeleka okumelana nokwelashwa
• Izifo zobuhlungu ezingapheli (ukusetshenziswa okungagunyaziwe)

Udokotela wakho uzohlola izimpawu zakho ngokucophelela ukuze anqume ukuthi i-amoxapine iyisinqumo esifanele esimweni sakho esithile. Bazocabangela izinto ezinjengomlando wakho wezokwelapha, eminye imithi oyithathayo, nokuthi usabele kanjani ekwelashweni kwangaphambilini.

Isebenza Kanjani I-Amoxapine?

I-Amoxapine isebenza ngokwandisa amazinga amakhemikhali athile obuchopho abizwa ngokuthi ama-neurotransmitters, ikakhulukazi i-serotonin ne-norepinephrine. Lawa makhemikhali adlala indima ebalulekile ekulawuleni imizwa yakho, ukulala, kanye nomuzwa wakho jikelele wokuzinza. Uma la ma-neurotransmitters ephansi, ungase uzwe izimpawu zokucindezeleka.

Lo muthi uthathwa njengomuthi onamandla ngokulinganisela uma uqhathaniswa neminye imithi emisha yokucindezeleka. Uvimba ukuthathwa kabusha kwala makhemikhali abalulekile obuchopho, okusho ukuthi amaningi awo ahlala etholakala ebuchosheni bakho ukuze asize ukuthuthukisa imizwa yakho. Cabanga ngakho njengokugcina izithunywa eziwusizo zisebenza ohlelweni lokuxhumana lobuchopho bakho.

Okuhlukile nge-amoxapine ukuthi futhi ivimba ama-receptors athile e-dopamine. Lesi senzo esingeziwe singasiza ngezimpawu ze-psychotic futhi singase libe negalelo ekusebenzeni kwayo ezimweni ezimelana nokwelashwa. Kodwa-ke, lokhu futhi kusho ukuthi kungaba nemiphumela emibi ehlukile uma iqhathaniswa neminye imithi yokucindezeleka.

Kufanele Ngiyithathe Kanjani I-Amoxapine?

Kufanele uthathe i-amoxapine ngendlela udokotela wakho ayichazayo, ngokuvamile ngomlomo ngaphandle noma ngaphandle kokudla. Abantu abaningi bakuthola kulula ukuyithatha nokudla ukuze kuncishiswe isisu esicasulayo. Udokotela wakho ngokuvamile uzoqala ngomthamo ophansi bese ewunyusa kancane kancane ngokusekelwe endleleni osabela ngayo futhi ubekezelele umuthi.

Isikhathi sokuthatha imithamo yakho sibalulekile ukuze uthole imiphumela emihle. Odokotela abaningi batusa ukuthatha i-amoxapine ngemithamo ehlukene usuku lonke, ngokuvamile izikhathi ezimbili noma ezintathu ngosuku. Abanye abantu benza ngcono ngokuthatha umthamo omkhulu ngesikhathi sokulala ngoba lo muthi ungenza ukozela.

Nawa amanye amathiphu abalulekile okuthatha i-amoxapine ngokuphepha:

• Yithathe ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo emzimbeni wakho
• Gwinya amaphilisi wonke ngamanzi - ungaqobi noma uwahlafune
• Ungayithatha nokudla noma ngaphandle kokudla, kodwa qiniseka
• Uma uzizwa ukozela, udokotela wakho angase alungise isikhathi sokuthatha imithamo yakho
• Ungayeki ukuyithatha kungazelelwe - udokotela wakho uzokusiza ukuthi unciphise kancane kancane

Khumbula ukuthi kungathatha amasonto amaningana ukuzwa izinzuzo ezigcwele ze-amoxapine. Ungadangali uma ungaboni ngcono ngokushesha - ubuchopho bakho budinga isikhathi sokujwayela umuthi.

Ngingayithatha isikhathi esingakanani i-Amoxapine?

Ubude besikhathi ozodinga ukuthatha ngaso i-amoxapine busekelwe esimweni sakho ngasinye nokuthi usabela kanjani emuthini. Abantu abaningi badinga ukuqhubeka beyithatha okungenani izinyanga eziyisithu esithupha kuya ngonyaka ngemuva kokuthi izimpawu zabo zokucindezeleka zithuthuke ukuvimbela ukuphindeka.

Udokotela wakho uzoqapha intuthuko yakho njalo futhi asize ekunqumeni ubude obufanele bokwelashwa kwakho. Abanye abantu bangase badinge ukuthatha i-amoxapine iminyaka eminingana, ikakhulukazi uma benokucindezeleka okuphindaphindayo noma ezinye izimo zempilo yengqondo eziqhubekayo. Abanye bangase bakwazi ukunciphisa kancane kancane umthamo wabo futhi ekugcineni bayeke umuthi.

Isinqumo sokuthi uqhubeke isikhathi esingakanani ukwelashwa siqukethe izici eziningana. Udokotela wakho uzocabangela ukuthi ukucindezeleka kwakho kwakunzima kangakanani, ukuthi lesi yisigameko sakho sokuqala noma uke waba nezigameko eziningi, nokuthi usabela kanjani emuthini. Bazophinda bacabangele noma yimaphi imiphumela emibi oyitholayo kanye nekhwalithi yakho yempilo iyonke.

Ziyini Izimo Ezingezinhle Zomuthi i-Amoxapine?

Njengayo yonke imithi, i-amoxapine ingabangela izimo ezingezinhle, nakuba kungewona wonke umuntu ozitholayo. Izimo eziningi ezingezinhle zithambile futhi zivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi. Kubalulekile ukwazi ukuthi yini ongayilindela ukuze ukwazi ukuxoxa nganoma yiziphi izinkathazo nodokotela wakho.

Izimo ezivamile kakhulu ongase uzithole zihlanganisa ukozela, umlomo owomile, nokuqunjelwa. Lezi zimo zivame ukulawuleka futhi zivame ukuncipha ngokuhamba kwesikhathi. Abanye abantu baphawula izinguquko ekudleni kwabo noma isisindo, okuzoqashwa udokotela wakho ngesikhathi sokwelashwa kwakho.

Ake sihlukanise izimo ezingezinhle ongase uhlangabezane nazo, siqale ngalezo ezivamile kakhulu:

• Ukozela noma ukukhathala
• Umlomo owomile
• Ukuqunjelwa
• Ukubona okungacacile
• Isiyezi lapho usukuma
• Ukukhuluphala
• Ubunzima bokuchama
• Ukujuluka okwengeziwe

Izimo ezingavamile kodwa ezingathi sína zingenzeka, futhi kufanele uthinte udokotela wakho uma uhlangabezana nanoma yiziphi zalezi. Lokhu kuhlanganisa ukushaya kwenhliziyo okungajwayelekile, isiyezi esikhulu, ukudideka, noma ukunyakaza okungajwayelekile. Udokotela wakho uzoxoxa ngalezi zingozi nawe futhi akuqaphele ngokucophelela, ikakhulukazi lapho uqala umuthi.

Kukhona futhi ezinye izimo ezingavamile kodwa ezingathi sína ezidinga ukunakekelwa kwezempilo ngokushesha:

• I-Tardive dyskinesia (ukunyakaza kwemisipha okungazithandeli)
• I-Neuroleptic malignant syndrome (umkhuhlane, ukuqina kwemisipha, ukudideka)
• Ukungezwani komzimba okukhulu
• Ukushaywa yisithuthwane
• Ushintsho olukhulu esigqi senhliziyo

Lezi zimo ezingathi sína azivamile, kodwa kubalulekile ukuzazi. Udokotela wakho uzoqaphela izinzuzo nezingozi ngaphambi kokunquma i-amoxapine futhi uzokuqaphela ngokucophelela ngesikhathi sokwelashwa kwakho.

Ubani Ongafanele Athathwe i-Amoxapine?

I-Amoxapine ayifanele wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Abantu abasanda kuba nesifo senhliziyo noma abanezifo zenhliziyo ezithile ngokuvamile akufanele basebenzise lo muthi. Udokotela wakho uzogwema ukuyinika uma usebenzisa eminye imithi ethile engase ihlangane ngendlela eyingozi.

Uma unomlando wokugula, i-glaucoma, noma i-prostate enwetshiwe, udokotela wakho uzodinga ukucabangela lezi zimo ngokucophelela. Ngenkathi i-amoxapine ingase isaba yindlela, uzodinga ukuqashwa eduze futhi mhlawumbe indlela yokulinganisa ehlukile.

Nazi izimo eziyinhloko lapho i-amoxapine ingase inganconywa khona:

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• Ukuhlaselwa yinhliziyo kwakamuva noma isifo senhliziyo esibi
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• Ukuthatha ama-MAO inhibitors noma ukuthi uwathathe ezinsukwini eziyi-14 ezedlule
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• Ukungezwani okwaziwayo ne-amoxapine noma imithi efanayo
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• Isifo sesibindi esibi
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• I-glaucoma ye-narrow-angle
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• Ukugcinwa komchamo okukhulu
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• Isigaba sokululama ngemuva kokuhlaselwa yinhliziyo
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Udokotela wakho uzosebenzisa ukuqapha okwengeziwe uma unesifo sikashukela, izinkinga ze-thyroid, noma umlando wokusebenzisa izidakamizwa kabi. Ukukhulelwa nokuncelisa ngamabele kudinga ukucatshangelwa okukhethekile, futhi udokotela wakho uzoxoxa ngobungozi nezinzuzo nawe uma uhlela ukukhulelwa noma usuvele ukhulelwe.

Amagama e-Brand e-Amoxapine

I-Amoxapine itholakala ngaphansi kwamagama amaningi e-brand, yize ivame ukunikezwa njengomuthi ojwayelekile namuhla. Igama lokuqala le-brand kwakuyi-Asendin, eyayisetshenziswa kakhulu lapho umuthi wethulwa okokuqala. Ungase usabona leli gama libalulwa ezincwadini zezokwelapha ezindala noma olwazini lweziguli.

Namuhla, amakhemisi amaningi anikeza i-amoxapine ejwayelekile, esebenza kahle njengenguqulo yegama le-brand kodwa ngokuvamile ibiza kancane. Ibhodlela lakho lemithi lizobonisa

Uma i-amoxapine ingakulungele, ziningi ezinye izinketho zokwelapha ukucindezeleka ezitholakalayo. Udokotela wakho angase acabange ngemithi emisha efana ne-SSRIs noma i-SNRIs, evame ukuba nemiphumela emibi embalwa futhi ivame ukubekezeleleka kalula. Lokhu kufaka phakathi imithi efana ne-sertraline, i-fluoxetine, noma i-venlafaxine.

Ezinye izidambisi zokucindezeleka ze-tricyclic nazo zingaba ezinye izindlela uma udinga lolu hlobo lomuthi kodwa ungenakukwazi ukubekezelela i-amoxapine. Imithi efana ne-nortriptyline noma i-desipramine isebenza ngendlela efanayo kodwa ingase ibe nemiphumela emibi ehlukile ekusebenzelayo kangcono.

Udokotela wakho uzokusiza ukuthi uhlole lezi ezinye izindlela ngokusekelwe ezimpawini zakho ezithile, umlando wezokwelapha, kanye nemigomo yokwelapha. Ngezinye izikhathi kuthatha ukuzama imithi eminingana ehlukene ukuze uthole leyo esebenza kahle kakhulu esimweni sakho esiyingqayizivele.

Ingabe i-Amoxapine Ingcono Kune-Nortriptyline?

Kokubili i-amoxapine ne-nortriptyline ziyizidambisi zokucindezeleka ze-tricyclic, kodwa zinezinye izinto ezibalulekile ezingenza enye ikufaneleke kakhulu kunenye. I-Amoxapine inemiphumela eyengeziwe kuma-dopamine receptors, engasiza ngezinhlobo ezithile zokucindezeleka kodwa ingase futhi ikhulise ingozi yemiphumela emibi ehlobene nokunyakaza.

I-Nortriptyline ivame ukucatshangwa ukuthi inemiphumela emibi engcono, ikakhulukazi mayelana nemiphumela yenhliziyo kanye nokuthuliswa. Itholakala futhi ngesimo esiwuketshezi, okungasiza abantu abanobunzima bokugwinya amaphilisi noma abadinga ukulungiswa kwemithamo enembile kakhulu.

Ukukhetha phakathi kwale mithi kuncike ezimpawini zakho ezithile kanye nomlando wezokwelapha. Udokotela wakho uzocabangela izinto ezifana nempilo yenhliziyo yakho, eminye imithi oyithathayo, nokuthi ngabe uke waba nezimpawu ze-psychotic kanye nokucindezeleka kwakho. Akukho ukukhetha okujwayelekile

I-Amoxapine idinga ukucatshangelwa ngokucophelela uma unesifo senhliziyo, njengoba singathinta ukushaya kwenhliziyo nomfutho wegazi. Udokotela wakho uzodinga ukuhlola isimo sakho senhliziyo esithile futhi angase ayale i-electrocardiogram (ECG) ngaphambi kokuqala ukwelashwa. Ezimweni eziningi, abantu abanezimo zenhliziyo ezingathí sina bangathatha ngokuphepha i-amoxapine ngokuqapha ngokucophelela.

Uma unesifo senhliziyo esibi, ukuhlaselwa yinhliziyo kwakamuva, noma izinkinga ezinkulu zokushaya kwenhliziyo, udokotela wakho cishe uzoncoma omunye umuthi wokucindezeleka. Bazohlola izinzuzo zokwelapha ukucindezeleka kwakho ngokumelene nezingozi ezingaba khona empilweni yakho yenhliziyo.

Kufanele ngenzeni uma ngithatha i-Amoxapine eningi ngengozi?

Uma ngengozi uthatha i-amoxapine eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma uzizwa ulungile. Ukweqisa kungaba kubi futhi kungase kubangele izimpawu ezinjengokudideka, ukuquleka, noma izinkinga zenhliziyo ezingase zingaveli ngokushesha.

Ungalindi ukubona ukuthi izimpawu ziyavela - funa ukunakekelwa kwezokwelapha ngokushesha. Uma kungenzeka, yiba nebhodlela lomuthi nawe uma ushayela ucingo ukuze uthole usizo, njengoba lolu lwazi luzosiza ochwepheshe bezokwelapha. Ungalokothi uzame ukuzihlanza ngaphandle uma uqondiswe ngqo ngumhlinzeki wezempilo.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Amoxapine?

Uma uphuthelwa umthamo we-amoxapine, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze nesikhathi somthamo wakho olandelayo. Kulokho, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, njengoba lokhu kungandisa ingozi yakho yemiphumela emibi.

Uma uvame ukukhohlwa imithamo, zama ukusetha i-alamu yefoni noma usebenzise umhleli wamaphilisi ukukusiza ukhumbule. Ukulinganisa okuqhubekayo kubalulekile ekugcineni amazinga aqinile omuthi ohlelweni lwakho futhi uthole inzuzo engcono kakhulu yokwelapha.

Ngingayeka nini ukuthatha i-Amoxapine?

Akufanele uyeke ukuthatha i-amoxapine ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa njengokucasuka, ikhanda elibuhlungu, kanye nezinguquko zemizwa. Udokotela wakho uzokusiza ukuthi unciphise kancane kancane umthamo wakho emasontweni amaningana noma izinyanga uma sekuyisikhathi sokuyeka umuthi.

Isikhathi sokuyeka sincike ekutheni usuwuthatha isikhathi esingakanani umuthi, ukuthi ukucindezeleka kwakho kulawulwa kahle kangakanani, kanye nengozi yakho yokuphindela emuva. Odokotela abaningi batusa ukuqhubeka nokwelashwa okungenani izinyanga eziyisithu kulezo zimpawu zakho zithuthuka ukunciphisa ingozi yokuthi ukucindezeleka kubuye.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Amoxapine?

Kungcono ukugwema utshwala ngenkathi uthatha i-amoxapine, njengoba kungakhuphula ukozela neminye imiphumela emibi. Utshwala bungase futhi lwenze izimpawu zokucindezeleka zibe zimbi futhi ziphazamise ukusebenza komuthi. Uma ukhetha ukuphuza ngezikhathi ezithile, zinciphise ezinani elincane futhi unake ukuthi uzizwa kanjani.

Xoxa nodokotela wakho mayelana nokusetshenziswa kwakho utshwala ngaphambi kokuqala i-amoxapine. Bangakunikeza isiqondiso esiqondene nawe ngokusekelwe emikhubeni yakho yokuphuza nempilo yakho yonke. Khumbula ukuthi utshwala bungaba yinkinga ikakhulukazi uma ubhekene nokucindezeleka, kungakhathaliseki ukusetshenziswa komuthi.