Imiphumela eminingi engavumelekile ye-amoxicillin ihlobene nokugayeka kokudla futhi ayibucayi. Uhudo, isithuthwane, ukuhlanza, nokucaneka yizona kuphela izimpendulo i-FDA label ekhuluma ngazo kubantu abangaphezu kuka-1% weziguli, futhi ngokuvamile ziyanyamalala phakathi nezinsuku ngemuva komthamo wokugcina. Inani elincane lezimpendulo ziyizimo eziphuthumayo zangempela, futhi leli khasi likutshela ngqo ukuthi yiziphi.

TL;DR: Izinto Ezibalulekile Okufanele Uzikhumbule

  • Imiphumela emine engavumelekile ye-amoxicillin kakhulu yilezi: uhudo, isithuthwane, ukuhlanza, nokucaneka. Konke okunye akuvamile noma kungavamile.
  • Isithuthwane akusho ukuthi une-allergy ku-penicillin eyohlala njalo. Cishe u-10% wabantu bayayibika; ngaphansi kuka-1% bangempela lapho kuhlolwa.
  • Izimpawu ezine zidinga ukuthi uyeke futhi uthole ukwelashwa okuphuthumayo: izimpawu ze-anaphylaxis, isikhumba esinezilonda noma esikhwela, uhudo olunegazi noma olunomkhuhlane, nokuhlanza okuphoqayo emahoreni ayi-1 kuya kwamane ngemuva komthamo enganeni.
  • Uhudo oluqala amasonto noma izinyanga ngemuva kwenkambo lisengakuchaza njengomphumela we-amoxicillin, hhayi ukuhlangana.
  • Imiphumela emincane ngokuvamile iyazanywa phakathi nezinsuku ezimbalwa ngemuva komthamo wakho wokugcina. Noma yini esaqhubeka ngemuva kwesonto idinga ukushayelwa ucingo.

Imiphumela Engavumelekile Ye-Amoxicillin Ejwayelekile Ihlasela Amathumbu, Hhayi Umzimba Wonke

Imiphumela engavumelekile ye-amoxicillin kakhulu yilezi: uhudo, isithuthwane, ukuhlanza, nokucaneka. Lezi zimpendulo ezine kuphela i-FDA-approved label ekhuluma ngazo kubantu abangaphezu kuka-1% weziguli. I-Amoxicillin ingabangela nokushintsha kombala wamazinyo okwesikhashana, futhi izimpendulo ezimbi njenge-anaphylaxis noma izimpendulo ezimbi zesikhumba kungavamile kodwa zidinga ukunakekelwa okuphuthumayo.

Lokho kushintsha kombala wamazinyo kudida abantu. I-MedlinePlus ithi ingaba phuzi, ensundu, noma empunga, futhi ayihlali njalo. Ukuxubha ngokuvamile kuyayilawula.

Amagama afana nokuthi "ejwayelekile" kanye "nokungavamile" afihla kakhulu, ngakho kuyasiza ukusebenzisa izigaba zezinombolo izinsiza zokubhekisela kwezokwelapha ezizishicilelayo: ejwayelekile kusho u-1% kuya ku-10% weziguli, kungavamile kusho u-0.1% kuya ku-1%, futhi kungavamile kakhulu kusho ngaphansi kuka-0.01%. Umphumela "ojwayelekile" yinto umuntu oyedwa kubantu abayishumi angayitholi.

Umbuzo owodwa ofanele ukuphendulwa ngokuqondile, ngoba imiyalelo yesidakamizwa iza ngezinhlobo eziningana: uhlobo lomphumela akushintshi ngendlela ebalulekile phakathi kwamamitha angama-250, angama-500, namathani angama-875. Ufuna uhlu olufanayo olufushane kunoma yiluphi uhlobo.

Isithuthwane Ngemuva Kwe-Amoxicillin Ngokuvamile Akusho Ukuthi U-Allergy Ku-Penicillin Eyohlala Njalo

Isithuthwane se-amoxicillin yisizathu esikhulu kunazo zonke abantu bachitha impilo yabo yonke bebhala "i-allergy ku-penicillin" ezifomini zokungena, futhi ngobuningi baleso silabelo singalungile. I-CDC ibika ukuthi cishe u-10% weziguli zase-US zibika i-allergy kuhlobo lwe-penicillin, kodwa ngaphansi kuka-1% bangempela lapho behlolwa ngokusemthethweni. Lokho kuhlukana akuyona into encane. Ukuthwala isilabelo esingaqinisekisiwe kukwenza usebenzise ama-antibiotics anezindawo ezibanzi, ezibiza kakhulu, futhi ngezinye izikhathi angasebenzi kangako iminyaka eminingi.

Ukuhlola akuyona i-guesswork futhi. Ukuhlolwa kwesikhumba, lapho kwenziwa, kungaphezu kuka-95% okuqondile ekutholeni i-allergy yangempela ye-IgE-mediated.

I-Mono yiyona nto eyaziwa kakhulu edida. Amaphesenti aphezulu abantu abane-mononucleosis esulela abathatha i-amoxicillin bathola isithuthwane esibanzi, cishe u-28% kuya ku-69% ezifundweni zezokwelapha, futhi i-label iyakugqamisa lokhu njengesixwayiso sabantu abakhethekile.

Nansi into engakutshelwa yiqhinga elikhulu kakhulu: iphutha elihambisanayo livamile njengoba nje. Ukuhlolwa kwesikhumba kubonisa ukuthi izithuthwane ezihambisana ne-mono zibonisa ukuboniswa kwezidakamizwa kwangempela, ngakho-ke "oh, kwakungama-mono nje" akulona isiphetho esiphephile ukuthi usifinyelele wedwa futhi.

Umehluko obonakalayo yilezi. Isithuthwane esiyisicaba, esingakhwikhizi esivela phakathi nenkambo sifanele ukuthwetshulwa futhi sihlolwe, ngokufanele ngokuhlolwa kwe-allergy okusemthethweni. Ama-hives, ukuvuvukala, noma yisiphi isimpawu sokuphefumula singesakolunye uhlobo ngokuphelele futhi singena esigabeni esilandelayo. Ungazikhiphi isijeziso, ungazilahli. Cela udokotela mayelana nokuhlolwa kwe-allergy esikhundleni sokuthwala isilabelo esingaqinisekisiwe impilo yakho yonke.

Izimpendulo Ezine Ze-Amoxicillin Ziyizimo Eziphuthumayo; Konke Okunye Kungalinda

Izimpawu zokuphendula kwe-allergy ye-amoxicillin yizona eziningi abantu abafuna ngempela, futhi impendulo ewusizo uhlu lokuhlunga kunetafula lokwenzeka. I-FDA label igama i-Stevens-Johnson syndrome, i-toxic epidermal necrolysis, i-DRESS, i-acute generalized exanthematous pustulosis, kanye ne-erythema multiforme, kanye nezimpendulo ze-anaphylactic ezimbi futhi ngezinye izikhathi ezibulalayo ezibikiwe ngezidakamizwa zohlobo lwe-penicillin. I-MedlinePlus ibeka ngqo ukuthi yini okufanele uyenze: yeka isidakamizwa futhi uthole ukunakekelwa okuphuthumayo.

Shayela u-911 noma uye egumbini lezimo eziphuthumayo manje uma:

  • Unama-hives, ukuvuvukala kobuso, izindebe, ulimi, noma umphimbo, noma ubunzima bokuphefumula noma bokugwinya. Phatha lokhu njenge-anaphylaxis kuze kube yilapho kuvezwa okunye.
  • Isikhumba sakho siyazilonda noma siyakhwela, noma unesithuthwane esibuhlungu esisabalala ngomkhuhlane, izilonda emlonyeni, noma ukucasuka kwamehlo.
  • Uhudo olunamanzi noma olunegazi olunomkhuhlane nezikliniki, kufaka phakathi uhudo oluqala ngemuva kwamaviki wokugcina wakho.
  • Kukhona ukuhlanza okuphindaphindiwe okubhekiswe emahoreni ayi-1 kuye kwamane ngemuva komthamo onokulala noma isikhumba esiluhlaza okwesibhakabhaka noma esimpunga, ikakhulukazi enganeni. I-label ibiza lokhu ngokuthi i-drug-induced enterocolitis syndrome, ebonakala kakhulu ezigulini ezineminyaka eyi-18 nangaphansi.

Bhukha ukuvakashelwa kungakapheli iviki elilandelayo uma:

  • Unesithuthwane ngaphandle kokuvuvukala noma izimpawu zokuphefumula.
  • Uhudo ludlulile amahora angama-48 kodwa akukho mkhuhlane futhi akukho gazi.
  • Uthola i-thrush noma izimpawu ze-yeast yomlomo wesithuthwane.
  • Imiphumela engavumelekile yenzeka kabi kangangokuthi ucabanga ukuphuma enkambeni.

Khuluma nodokotela ngaphambi kokuba uqale uma:

  • Uke waba nempendulo yanoma iyiphi idakamizwa yohlobo lwe-penicillin.
  • Une-mono noma ungase ube nayo.
  • Une-kidney impairment, noma usemdala futhi uhlanza imithi kancane kancane.
  • Ukhulelwe noma uyamuncisa.
  • Uthatha eminye imiyalelo kadokotela.

Uma ungabaza ukuthi yisiphi isigaba osikhona, isihlungi sezimpawu samahhala se-August AI singakusiza ukuthi uhlunge ubucayi emaminithini ambalwa. Kuyizindlu, hhayi ukuxilongwa.

Uhudo Lwe-Amoxicillin Luza Ngezinhlobo Ezimbili Futhi Okunye Kuphela Okuyingozi

Ingabe i-amoxicillin ibangela uhudo? Yebo, futhi yiyona impendulo ebikwa kakhulu ku-FDA label, ethinta abangaphezu kuka-1% weziguli. Kodwa umbuzo obalulekile ukuthi yiziphi izinhlobo ezimbili ezinazo.

Inhlobo ejwayelekile yizimo ezihambisana ne-antibiotic diarrhea. Izinkululo ezixegayo ziqala ezinsukwini zokuqala zenkambo, akukho mkhuhlane futhi akukho gazi, futhi izinto ziyazanywa phakathi nezinsuku ngemuva komthamo wokugcina. Kuyacasula, akukhathazi.

Inhlobo yesibili yi-Clostridioides difficile-associated diarrhea, futhi ibukeka ngokuhlukile: izinkululo ezinamanzi noma ezinama gazi anemikhuhlane nezikliniki zesisu. Ubuhlungu buvela kuhudo oluncane kuya ku-colitis ebulalayo, futhi i-label ithi ingenzeka izinyanga ezimbili ngemuva kokuyeka i-amoxicillin. I-MedlinePlus inikeza ifasitela elifanayo elihlala izinyanga ezimbili noma ngaphezulu, futhi izincwadi zokubhekisela zezidakamizwa zabathengi zichaza uhudo oluhlala izinyanga ezimbili.

Ngakho-ke nansi imiyalelo cishe akekho omunye okukhuluma ngayo ngokucacile: ukuqedela inkambo akukuvimbeli isikhathi. Uma uthola uhudo olusha ezinyangeni ezintathu, ezinhlanu, noma ezishumi ngemuva kwe-capsule yakho yokugcina, lokho kusadingeka umlando ofanele futhi kusadingeka ukuthi uhlolwe. Khuluma nge-antibiotic ngegama lapho ushayela. Odokotela abangakwazi ukuthi uthathe i-amoxicillin ngeke bakuhlole into eyichazayo.

Imiphumela Engavumelekile Ye-Amoxicillin Ejwayelekile Iyanyamalala Ngemuva Kwezinsuku Ezimbalwa Kusukela Emthamo Wakho Wokugcina

Imiphumela engavumelekile ye-amoxicillin ihlala isikhathi esingakanani? Kwabajwayelekile, izinsuku ezimbalwa kakhulu, futhi ngokuvamile ziyazanywa phakathi nezinsuku ezimbalwa zokuqedela inkambo. Isithombe sokuqala sinokusetshenziswa kakhulu kunomfanekiso wobude, ngoba ukwazi ukuthi into ivame ukuvela nini kukutshela ukuthi usejamboni noma ngaphandle kwegeji.

  • Ukucaneka, ukuhlanza, izinkululo ezixegayo: ngokuvamile ezinsukwini zoku-1 kuye kwezimbili.
  • Isithuthwane: ngokuvamile ezinsukwini zesi-3 kuye kweziyisikhombisa.
  • Izimpendulo ze-allergy: kunoma iyiphi indawo kusuka cishe ihora elilodwa kuya ezinsukwini eziyi-12 ngemuva komthamo.
  • Uhudo lwe-C. difficile: kufika ezinyangeni ezimbili noma ngaphezulu ngemuva komthamo wokugcina, ngokuya nge-FDA label.

I-Amoxicillin ngokwayo iyasikhipha emzimbeni ngokushesha. Akuyona imithi ehlala amasonto, yingakho izimpawu ezisaqhubeka isonto lonke ngemuva komthamo wakho wokugcina zivame ukukhomba okunye ngaphandle komphumela ojwayelekile wedakamizwa. Lokho kuyishayele ucingo, hhayi ukulinda nokubona.

Ukwesula okukodwa okufanele kugcinwe: ukunciphisa umsebenzi wezinso kubantu abadala kucisha ukushesha, okungandisa noma okwenze imiphumela engavumelekile ibe nzima, kodwa usayizi womthamo kuyisinqumo sikadokotela futhi awuzukuzenzela.

Uma I-Amoxicillin Ikubangela Ukuba Ukhathale, Bheka Okokuqala Ngokugula

Ingabe i-amoxicillin ikwenza ukhathele? Ngokuvamile hhayi ngqo. Ukukhathala akukho phakathi kwezinkulumo ze-FDA label ezingaphezu kuka-1% zezimpendulo ezibi, okuyihudo, isithuthwane, ukuhlanza, nokucaneka. Ukukhathala okuningi ngesikhathi senkambo yigciwane olwelashayo, lihambisana nokulala okuphazamisekile, ukuncipha kokudla, nokudonswa kwamanzi okuncane kusuka ekudabeni kwe-GI. Kufana nokudideka esikukhulumayo kwezimpawu ze-Tamiflu kubantu abadala, lapho abantu bebeka ukukhathala komkhuhlane ku-antiviral.

Ukukhathala okubangelwa yidakamizwa kungavamile, kodwa akukhona ukuthi akukho, futhi kunezimpawu ezithile ezishintsha ukuhlanganiswa. Phakamisa uma ukukhathala kuhambisana nesikhumba esiluhlaza okwesibhakabhaka, ukuphuzi kwamehlo noma isikhumba, ukulinyazwa okungajwayelekile, umchamo omnyama, noma umkhuhlane. Lokho kubhekisela ezindaweni zesibindi nezegazi ezibhalisiwe kunokuhamba okujwayelekile ngemuva kokugula.

Ezinye izinhlobo ezimbili zifanele ukushayelwa ucingo: ukukhathala okuqala ngemuva kokuphela kwenkambo, nokukhathala okwenzeka kabi ngenkathi ukugula kucacile ukuthi kuyalulama. Bobabili bayaphambana nendlela elindelekile.

Ungakwazi Ukunciphisa Imiphumela Engavumelekile Engaphezu Kweminingi Ngaphandle Kokuyeka I-Antibiotic

Abantu abaningi abayeka i-antibiotic ngaphambi kwesikhathi bayakwenza lokho ngenxa yokucaneka ukuthi ukudla kungakwelapha. Thatha imithamo yakho ngokudla uma isisu sakho siyinkinga. I-Amoxicillin iyawumunca kahle noma yikuphi, ngakho-ke lokhu kulungiswa kwamahhala. Gcina uketshezi nama-electrolyte aphezulu uma izinkululo zixegile, hlukanisa imithamo ngokulinganayo phakathi nosuku esikhundleni sokuyihlanganisa, futhi qedela inkambo ngaphandle kokuba udokotela akutshele okunye.

Abanye abantu badinga okungaphezu kokuzisiza. Abantu abadala bancisha i-amoxicillin kancane kancane ngenxa yokuncishiswa komsebenzi wezinso, okwandisa ubungozi bempumela engavumelekile, kodwa ukulungiswa komthamo kuyisinqumo sikadokotela futhi akuzukuzenzela. Ezinye izigaba ezidinga ingxoxo ngaphambi noma ngesikhathi sokwelashwa: noma ngubani one-mono esebenza noma ocabanga ukuthi uyayithola, noma ngubani oye wabhekana nempendulo kuhlobo lwe-penicillin, noma ngubani one-kidney impairment, kanye nezingane, ngoba i-drug-induced enterocolitis syndrome igxile ezigulini ezineminyaka eyi-18 nangaphansi.

Uma imiphumela emincane ikuqeda amandla, isinyathelo esingcono ukubuza ngokushintsha ama-agent, hhayi ukuyeka ngasese. Ukuhlolwa okungaphuthumayo okuku-inthanethi ne-August kubiza u-$39, futhi udokotela onelayisense lase-US ubuyekeza izimpawu zakho futhi anqume ukuthi ingabe i-prescription, ukushintsha, noma uhlelo oluhlukile lulufanele. Cacisa ukuthi yini okungekwenzi: i-anaphylaxis, isithuthwane esinezilonda, nohudo olubi olunegazi ludinga u-911 noma ukunakekelwa mathupha, hhayi ukuvakashelwa kwevidiyo. Uma ukushintsha noma ukugcwalisa kabusha kuyisiphetho, kufanelekile ukwazi ukuthi i-amoxicillin ibiza malini ngaphandle komshwalense ngaphambi kokuba uyigcwalise.

Imibuzo Evame Ukubuzwa

Ungasebenzisa utshwala ngenkathi uthatha i-amoxicillin?

Yebo, ngokwetheknoloji. Ngokungafani ne-metronidazole, i-amoxicillin ayihlangani ngokuqondile notshwala, ngakho-ke isiphuzo ngeke sibangele impendulo. Inkinga engokoqobo yisibambezelo: utshwala bubhebhethelela ukucaneka nokudonswa kwamanzi, okuyizikhalazo ezimbili ezibucayi kakhulu kulokhu kudakisa. Uma isisu sakho singalungile noma unezinkululo ezixegayo, yiyeke kuze kube yilapho inkambo isiqediwe.

Ingabe i-amoxicillin yamamitha angama-500 kanye namathani angama-875 ibangela imiphumela engavumelekile ehlukile?

Ngokuvamile hhayi. Uhlobo lwempendulo akushintshi ngohlobo; uhlu olufanayo olufushane lusebenza ku-250 mg, 500 mg, kanye no-875 mg. Ukuchayeka okuphezulu kwansuku zonke kungenza ubuhlungu be-GI buvame kancane kwabanye abantu, kodwa akubangeli izinhlobo ezintsha zemiphumela. Imiyalo ye-dose-specific ingeyombhalisi wakho, owakhetha uhlobo ngesizathu.

Ingabe i-amoxicillin kufanele ithathwe ngokudla?

Ngezinye izikhathi. I-Amoxicillin ingathathwa ngokudla noma ngaphandle kokudla, okungavamile phakathi kwama-antibiotics futhi kulula kakhulu. Thatha ngayo ngokudla uma ukucaneka kuyinkinga yakho. Umkhuba obalulekile yisibambezelo esilinganayo: imithamo ngamavawuli alinganayo egcina amazinga edakamizwa azinzile kunemithamo emithathu ehlangene ntambama ngoba ukhohlwe umthamo wasekuseni.

Ingabe i-amoxicillin yenza ama-pill okuvimbela ukukhulelwa angasebenzi kangako?

Ngokuvamile hhayi. AmaPenicillins akunjalo phakathi kwama-antibiotics abhalisiwe anciphisa ukusebenza kwama-contraceptive ahlobene nama-hormone; imithi yohlobo lwe-rifampin iyimikhawulo eqinisekisiwe. Ubungozi obuqinisile bungahambisani: uma i-amoxicillin ibangela ukuhlanza noma uhudo olunzulu, ungase ungayifaki kahle i-pill. Sebenzisa indlela yokulondoloza ngaleso sikhathi kanye nesonto elilandelayo, futhi ucele umbhali wakho uma ungabaza.

Ingabe i-amoxicillin ingabangela ukutheleleka nge-yeast noma i-oral thrush?

Yebo. I-mucocutaneous candidiasis ivela ohlwini lwezimpendulo ezibi ze-FDA label. Ama-antibiotics ayakhipha amagciwane avame ukulawula i-yeast, ngakho-ke ukukhula ngokweqile emlonyeni noma esithweni sangasese kuyimiphumela elindelekile kunokuba uphawu lokuthi kukhona okungahambanga kahle. Kuyanakeleka futhi ngokuvamile akusho ukuyeka i-antibiotic. Ubufakazi be-probiotic bungahlanganiswa, ngakho ungabatholi ngokwabo.

Ngingakwazi ukuyeka ukuthatha i-amoxicillin ngaphambi kwesikhathi uma imiphumela engavumelekile ingihlupha?

Cha. Ukuyeka ngaphambi kwesikhathi kushiya igciwane lihlangene futhi kunikeza amagciwane asaphila isiqalo esihle. Izimo ezikhethekile yizimpawu eziphuthumayo ezingenhla, lapho ukuyeka kuyisinyathelo esilungile futhi i-label ikusho. Ngokucaneka okuncane noma izinkululo ezixegayo, shayela ngaphambi kokuba uyeke. Udokotela angakwazi ukulungisa isikhathi, engeze ukunakekelwa okusekelayo, noma akushintshele kwelinye i-agent.

Imiphumela Engavumelekile Ngabe Kusho Ukuthi I-Amoxicillin Iyasebenza?

Cha. Lena yimithombo engapheli ngaphandle kwesisekelo. Imiphumela engavumelekile ibonisa ukuthi umzimba wakho uwubhekana kanjani nedakamizwa, hhayi ukuthi liyawabulala kangakanani amagciwane. Abantu abaningi bathatha inkambo ephelele ngaphandle kwezimpawu futhi bacacise igciwane labo ngokuphelele. Nquma ukuthi iyasebenza yini ngokusekelwe emkhuhlaneni wakho, ubuhlungu, namandla emavikini angu-48 kuye kwangu-72, hhayi ngokusekelwe esiswini sakho.

Isiphetho Mayelana Nemiphumela Engavumelekile Ye-Amoxicillin

Izimpendulo ezijwayelekile zihlobene nokugayeka kokudla, azibucayi, futhi azihlali isikhathi eside, futhi azisona isizathu sokuyeka inkambo. Uma uthola isithuthwane, siyihlole kunokuba uzibeke njengomuntu one-allergy ku-penicillin impilo yakho yonke: cishe u-10% wabantu bayayibika leyo allergy, kanti ngaphansi kuka-1% bayatholakala beyingempela lapho behlolwa. Futhi khumbula ukuthi uhudo lwe-C. difficile lungaqala ngemuva kwezinyanga ezingaphezu kwezimbili kusuka kumthamo wakho wokugcina, ngakho izimpawu zasekuhlehlweni zisengaphakathi kwesikhathi. Uma ungabaza, chaza isikhathi kudokotela; isikhathi siyinto ehlukanisa okuvamile kokubucayi lapha.

Ukuvimbela: Lesi sihloko senzelwe izinjongo zolwazi kuphela futhi akubhekwa njengeseluleko sezokwelapha. Hlala ukhuluma nomhlinzeki wezempilo onekhono ukuze uthole ukuxilongwa nezinqumo zokwelashwa. Uma ubhekene nesimo esiphuthumayo sezokwelapha, shayela u-911 noma uye egumbini lezimo eziphuthumayo eliseduze ngaso leso sikhathi.