I-Augmentin ekuguleni kwamathumbu emiphongolo ingeyokuqala kuphela lapho isifo siwubhaktheriya: 875 mg/125 mg njalo emahoreni angu-12 iminyaka emihlanu kuya kweyisikhombisa kubantu abadala. Ukuthuthuka kuqala emahoreni angu-48 kuya ku-72, hhayi ngalolo suku. Njengoba iningi lokugula kwamathumbu emiphongolo lingama-viral, umuthi awenzi lutho ezigamekweni eziningi.

TL;DR: Okubalulekile okubalulekile

  • Indlela ejwayelekile yabantu abadala: 875 mg/125 mg njalo emahoreni angu-12, noma 500 mg/125 mg njalo emahoreni angu-8.
  • Abantu abadala bayithatha iminyaka emihlanu kuya kweyisikhombisa. Abantwana yibo abathola iminyaka eyi-10 kuya kweyiyi-14.
  • Yihlole kuwase mahoreni angu-48 kuya ku-72. Isinqumo sosuku olulodwa asinaso nhlobo.
  • Ukuphazamiseka ngemuva kwamahora angu-72, noma ukungashintshi kusukela ngosuku lwesithathu kuya kolesihlanu, kusho ukuthi shayela umbhali.
  • Ukuvuvukala kwamehlo, ukushintsha kombono, noma ubuhlungu bekhanda obukhulu obunomzwa wentamo yizinkinga zegumbi lezenzo eziphuthumayo, hhayi imiphumela eseceleni.

I-Augmentin Ekuguleni Kwamathumbu Emiphongolo Isebenza Kuphela Lapho Isifo Siwubhaktheriya, Futhi Iziningi Azilokho

I-Augmentin ekuguleni kwamathumbu emiphongolo iyindlela yokuqala eyinhloko ye-acute bacterial rhinosinusitis, kodwa izibalo ezincane kakhulu zezifo zamathumbu emiphongolo ziyakufanelekela. Indlela ejwayelekile yabantu abadala ingama-875 mg/125 mg njalo emahoreni angu-12 iminyaka emihlanu kuya kweyisikhombisa. Amabhaktheriya aqala ukufa emahoreni okuqala komthamo wokuqala, kodwa ukuthuthuka okubonakalayo kuvame ukuqala kuwase mahoreni angu-48 kuya ku-72. Akukho ukuhlolwa okusemthethweni ngalolo suku ukuthi iyasebenza yini.

Isizathu sibalulekile. I-CDC ibeka isabelo sezifo zamathumbu emiphongolo ezibangelwa yizi-viral cishe ku-90 kuye ku-98 percent, futhi i-antibiotic ayenzi lutho kwibhaktheriya. Ngakho-ke ngaphambi kokuthi umbuzo womthamo ufanele ukubuzwa, ukuxilongwa kufanele kuphumelele.

Izimo ezintathu zibheke ebhalteriyeni:

  • Izimpawu ezingaphezu kwezinsuku ezingu-10 ngaphandle kokuthuthuka.
  • Ukuqala okukhulu: umkhuhlane ongama-102°F (39°C) noma ngaphezulu ngokukhishwa kwamanzi emqaleni okunamafutha kanye nobuhlungu bobuso iminyaka emithathu kuya kweyine ilandelana.
  • Ukuphazamiseka kabili: uyathuthuka emahoreni amane kuya kweyisikhombisa, bese uwohloka kancane.

Ukukhishwa okunobukhulu, okuluhlaza okotshani, noma okuphuzi akufakiwe ohlwini. Ukukhishwa okunombala kuvamile ekuguleni okubangelwa yizi-viral futhi akubikezeli lutho. Lapho isimo esisodwa sezintathu sikhona, i guideline ye-IDSA ka-2012 ibiza i-amoxicillin-clavulanate, hhayi i-amoxicillin eyisiqheshi, njengendlela yokuqala yokwelashwa kwabantu abadala nezingane.

Umthamo Wakho Uphuma Emibhalweni Yakho Yengozi, Hhayi Ngokuthi Uzizwa Kanjani Kabi

Umthamo we-Augmentin wokugula kwamathumbu emiphongolo abantu abadala abawutholayo uyisinqumo mayelana nokungamelani okwenzeka, hhayi ngokuthi bazizwa kanjani kabi. I-IDSA inamathambo amabili ajwayelekile abantu abadala: 875 mg/125 mg njalo emahoreni angu-12, noma 500 mg/125 mg njalo emahoreni angu-8. Noma yiliphi kuzo lihlanganisa i-sinusitis yomphakathi evamile.

Indlela ephakeme yokukhishwa okwandisiwe ye-2,000 mg/125 mg kabili ngosuku iyatholakala, futhi igcinwa kunokuba ibe evamile. Icatshangelwa ukugula okukhulu, izindawo ezinokumelana okuphezulu kwe-pneumococcal, ukuchayeka kosuku, ubudala bungaphezu kwama-65 (noma ngaphansi kwama-2), ukulaliswa esibhedlela muva nje, ukusetshenziswa kwe-antibiotic emavikini angu-90 adlule, noma isimiso sokuzivikela esibuthakathaka. Ngakho-ke umthamo we-Augmentin wokugula kwamathumbu emiphongolo abantu abadala abawuthola ukhombisa umlando wabo, hhayi isikolo sezimpawu zabo.

Okuphezulu akusho ukuthi kungcono. Isifundo esingahleliwe sango-2021 ku-JAMA Network Open sithole ukuthi i -dose ephezulu ye-amoxicillin-clavulanate ayizange isebenze njengomthamo ojwayelekile kubantu abadala abane-sinusitis ebukhali.

Isicupho esisebenzayo: amaphilisi amabili angu-250 mg akufani ne-pilisi eyodwa engu-500 mg. Lonke uhlobo lunezibalo ezifanayo eziqinisekile 125 mg we-clavulanate, ngakho ukuphindeka kabili kwamaphilisi kuphinda kabili i-clavulanate. Ungalokothi uhlanganise umthamo kusuka ezinsalela zerecipi endala.

Iminyaka Emihlanu Kuya Kweyisikhombisa Yiyona Inkinga Yabantu Abadala, Futhi Okungaphezulu Akukuvuni Kakhulu

Izinsuku ezingaki zokuthatha i-Augmentin yokugula kwamathumbu emiphongolo inempendulo emfushane kubantu abadala: iminyaka emihlanu kuya kweyisikhombisa ye-acute bacterial rhinosinusitis engafakiwe. Isibalo sezinsuku ezingu-10 kuya kweyiyi-14 osibona kwenye indawo siyangempela, kodwa singabantwana.

Izifundo ezifushane zabantu abadala zifana nezinde ngesilinganiso sokwelashwa ngenkathi zikhiqiza isifo sohudo esincane kanye nomfutho omncane wokumelana. Leso yisona sizathu sonke.

Izinsuku ezingaki zokuthatha i-Augmentin yokugula kwamathumbu emiphongolo nayo iyimpendulo emayelana nezilingo ezimbili. Owokuqala uyeka ngosuku lwesithathu ngoba uzizwa ulungile, okushiya ngemuva ngokuchazekayo i-subpopulation yama-bakteriya eqinile. Eyesibili yikulula inkambo ngamaphilisi asalele emuva. Inkambo ebonakala idinga ukwelulwa iyinkambo edinga ukuhlaziywa kabusha. Uma ufuna indlela yokupheka ye-prescription ejwayelekile, nansi izinsuku eziningaki okufanele uzithathe.

Ukuzizwa Ungalungile Ngosuku Lwesibili Akusho Ukuthi Ayisebenzi

Kungakanani isikhathi okuthatha i-Augmentin ukuba isebenze kuncike kokwengu kwesikhathi sokuphila esinye, futhi abafundi bavame ukuhlanganisa zonke izilinganiso zibe munye umbuzo ongafanelekelekayo.

Isikhathi esingu-1 ukumuncwa. Amazinga egazi afinyelela phezulu cishe emahoreni amabili ngemuva komthamo. Ukubulala ibhaktheriya kakade kuyenzeka ngosuku loku-1, kude kakhulu ngaphambi kokuba ubuso bakho bukwazi.

Isikhathi esingu-2 ukuthuthuka kwezimpawu, okuvame ukuba kubonakale kuwase mahoreni angu-48 kuya ku-72. Lapho abantu bebuzwa ukuthi "kungakanani isikhathi okuthatha i-Augmentin ukuba isebenze," lesi ngaso sonke isikhathi isikhathi abasicashelayo.

Isikhathi esingu-3 sokubuyiselwa, esisebenza isikhathi sonke senkambo nangaphezu kwayo. Ukuminyana okushiyekile nokukhwehlela kungahlala isonto noma ngaphezulu ngemuva kwephilisi lokugcina.

Nansi into abantu abaningi abayishoyo: esifundweni esingafani sango-2021, cishe amaphesenti angu-44 abantu abadala bazizwa "ngcono kakhulu" noma bengenazo izimpawu ngosuku lwesithathu, befika cishe kuwomaphesenti angu-82 ngosuku lweshumi. Ukuzizwa ungathinteki ngosuku lwesibili kukubeka eningi, hhayi engozini.

Bukela isimpawu esifanele. Ingcindezi yobuso nokukhathala kuvame ukuthuthuka kuqala. Ukuminyana kwemiphongolo yikona okokugcina ukuhlanjululwa, yingakho kwenza isibonakaliso esibukeka kabi sokuqhubeka, futhi yingakho isifo samathumbu emiphongolo ngaphandle kokuminyana singaba yinto edida kakhulu ukulandelela.

Ukungathuthuki Ngosuku Lwesithathu Kuyisibonakaliso Sokwenza, Hhayi Sokulinda

I-Augmentin ayisebenzi ekuguleni kwamathumbu emiphongolo kuyisigameko esichaziwe sezokwelapha, hhayi imizwa. I -threshold ye-IDSA ilula kakhulu: izimpawu ezibhekene nezinga eliphezulu emva kwamahora angu-48 kuya ku-72 yokwelashwa, noma ukungathuthuki nhlobo kuwase mahoreni amathathu kuya kwamahlanu, kusho ukuxhumana nombhali. Ukuthuthuka akulindelekile emahoreni angu-24 okuqala, ngakho-ke isinqumo sosuku olulodwa akuyona idatha esemthethweni.

Lapho inkambo ihluleka ngempela, kuvame ukusho izinto ezintathu. Isidalwa asibuthakathaka. Isifo asikaze sibe ubhaktheriya futhi singama-viral noma i-allergic. Noma kukhona into eyenziwa ngesakhiwo endleleni, njengokuvimbela i-sinus ostium noma ama-nasal polyps.

Izinyathelo ezilandelayo zodokotela ziyefana: ukushintsha ibhaktheriya, ukucela ukuhlolwa noma ukuhlolwa kwezithombe, noma ukuvula kabusha ukuxilongwa ngokuphelele. Ukuqagela ekhaya akukho inguqulo yalokhu esebenzayo.

Uma ungaphezu kwesikhathi samahora angu-72 futhi ubambekile, i-August's $39 online urgent care visit ikuxhumanisa nodokotela ogunyazwe yi-US ongabuyekeza isikhathi sakho futhi anqume ukuthi ingabe i-prescription, ukushintsha, noma ukuhlolwa komuntu siqu kufanelekile yini. Akukho i-prescription eqinisekisiwe, futhi ukuvakashelwa kwevidiyo akukwazi ukukubona izitho zemiphongolo yakho, ukuphakamisa ikhala lakho, noma ukuphatha izimpawu zamehlo nezinye eziboniswayo ngezansi. Lezo ziya egumbini lezenzo eziphuthumayo.

I-Clavulanate Yikho I-Augmentin Ephazamisa Isisu Sakho, Futhi Kungani Ukudla Kusiza

Isifo sohudo kanye nesicanucanu kubangelwa ikakhulukazi yi-clavulanate, hhayi yi-amoxicillin. Leli qiniso elilodwa lichaza ukuthi kungani i-Augmentin inzima esiswini kunama-amoxicillin ayisiqheshi, nokuthi kungani imiyalelo iyokuba uthathe umthamo ngamunye ekuqaleni kokudla: ukudla kunciphisa umthelela we-GI futhi kuthuthukisa ukumuncwa kwe-clavulanate ngasikhathi sinye.

Uphuthelwe umthamo ohlelweni lwamahora angu-12? Thatha lapho ukhumbula, ngaphandle kokuba umthamo olandelayo ungaphezu kwamahora amane, lapho-ke uwudlule. Ungalokothi uphinde ubeke kabili, ngoba ukuphindeka kabili kwamaphilisi kuphinda kabili i-clavulanate nobuhlungu besisu ngayo.

Izitulo ezibuthakathaka ziyabekezeleleka futhi akuyona imbangela yokuyeka inkambo. Isifo sohudo esibi, esamanzi, noma esinegazi esinobuhlungu besisu obubhekene nezinga eliphezulu sifana nokunye, futhi sifanelekela ucingo ngalolo suku ukuthi kungenzeka kube yi-C. difficile. Emininingwane eyengeziwe mayelana nohlu olugcwele lwez imiphumela eseceleni ye-Augmentin kufanele ifundwe ngaphambi kosuku loku-1.

Ezinye Izimpawu Phakathi Nokwelashwa Ziyizimo Eziphuthumayo, Hhayi Imiphumela Eseceleni

Izifo zamathumbu emiphongolo zihlala eduze kwamehlo nobuchopho. I-orbital cellulitis nokudlulisela kwe-intracranial ziyivelakancane, futhi yisona sizathu izimpawu ezilandelayo zingadlula umbhali wakho ngokuphelele.

Shayela u-911 noma uye egumbini lezenzo eziphuthumayo manje uma:

  • Kukhona ukuvuvukala, ububomvu, noma ukucubuzeka eduze kwamehlo, noma ukushintsha okusha kombono njengokubona kabili noma ukulahlekelwa kombono.
  • Unezinhlungu zekhanda ezibi ngomzwa wentamo, ukudideka, ukulala, noma ukuvalelwa.
  • Ubuso bakho noma umphimbo kuvuvuka, noma uthola ama-hives, ukukhwehlela, noma ubunzima bokuphefumula noma ukugwinya.
  • Unezifo eziqinile zesifo sohudo ezinobuhlungu besisu obubhekene nezinga eliphezulu.

Bhukha ukuvakashelwa phakathi neviki elizayo uma:

  • Umkhuhlane ongama-102°F (39°C) noma ngaphezulu uhlala ngaphezu kwezinsuku ezintathu kuya ngaphambili kwe-antibiotics.
  • Izimpawu ziyathuthuka bese ziyalulama.
  • Lona umkhuhlane wakho wesine wamathumbu emiphongolo ngonyaka.
  • Ubona isikhumba noma amehlo aphuzi, umchamo omnyama, noma ukukhathala okukhulu, okungaba uphawu lokulimala kwesibindi okubangelwa imithi.

Khuluma nodokotela ngaphambi kokuba uqale uma:

  • Une-allergy kunoma iyiphi i-penicillin noma i-cephalosporin.
  • Uke waba ne-jaundice noma izinkinga zesibindi nge-Augmentin ngaphambili.
  • Unesifo samathambo noma umsebenzi wokukhipha isibindi obuncishisiwe.
  • Ukhulelwe noma uncelisa.
  • Uthatha i-allopurinol, i-methotrexate, noma i-warfarin.

Isiphetho

Izinombolo ezintathu zilayisha leli khasi: 875 mg/125 mg njalo emahoreni angu-12, iminyaka emihlanu kuya kweyisikhombisa, nokuhlolwa kabusha kuwase mahoreni angu-48 kuya ku-72. Zonke ezintathu ziyachazela imfuneko, okuyinto ukuxilongwa okunempela kobhaktheriya esikhundleni sosuku lwesine lokubanda. Qedela inkambo egcwele ngisho noma uzizwa kahle ngosuku lwesithathu. Uma ubhekene nezinga eliphezulu ngemuva kwamahora angu-72 noma ungashintshiwe ngosuku lwesihlanu, i-Augmentin yokugula kwamathumbu emiphongolo ayilona impendulo obuyidingayo, futhi lokho kuyizingcingo okufanele zenziwe kunokuba yisonto elizolindelelwa.

Imibuzo Evame Ukubuzwa

Ngingathatha ini esikhundleni se-Augmentin uma ngingenawo i-penicillin?

Cha, i-Augmentin ayiyona indlela yokukhetha enokuqwashisa kwe-IgE-mediated penicillin allergy yangempela, ngoba iyona i-penicillin. Kubantu abadala, odokotela bavame ukuyisebenzisa i-doxycycline njengendlela ejwayelekile, kanti izibulala-bhakteriya ze-fluoroquinolone zeziphefumulo ziyindlela yesibili egcinelwe abantu abangakwazi ukuthatha i-doxycycline. Chaza ukusabela kwakho ngokucacile, ngoba ukuqubuka okungaphandle ebuntwaneni nokuhlaselwa okweqiniso kuvula izinqumo ezahlukene.

Ingabe i-Augmentin iphephile ukuyithatha ekuguleni kwamathumbu emiphongolo ngesikhathi sokukhulelwa?

Yebo. I-Amoxicillin-clavulanate ingelinye lama-antibiotics avame ukusetshenziswa ekukhulelweni lapho kugunyazwe ukugula okubhaktheriya kwamathumbu emiphongolo, futhi ama-penicillins anomlando omude kakhulu wokuphepha phakathi kwayo yonke imikhakha yama-antibiotics ezigulini ezikhulelwe. Tshela umbhali wakho ukuthi ukhulelwe noma uncelisa, ngoba kushintsha ukuthi yiziphi izindlela ezihlala etafuleni uma inkambo yokuqala ihluleka.

Ingabe i-Augmentin isebenza ngokushesha kune-amoxicillin eyisiqheshi ekuguleni kwamathumbu emiphongolo?

Cha. I-Clavulanate ayisheshisi lutho. Ivimba ama-enzyme e-beta-lactamase, okwandisa ukubhekwa ezinhloboni ze-Haemophilus influenzae ne-Moraxella catarrhalis ezingayilimaza i-amoxicillin. Lelo yinzuzo yokubhekwa, hhayi inzuzo yobuhlakani. Zombili izidakamizwa zilandelisa umkhawulo wezimpawu ezifanayo wamahora angu-48 kuya ku-72 lapho zisebenza.

Ngingaphuzwa utshwala ngenkathi ngithatha i-Augmentin?

Kuvame ukungabi njalo. Akukho ukusebenzisana okuyingozi okuhlobene nokuphuza utshwala njengakubangani be-metronidazole, ngakho-ke ukuphuza okukodwa akubanga nomonakalo omkhulu. Inkinga esebenzayo yileyo ephindaphindayo: utshwala bubhekana nezinga eliphezulu lobuthakathaka nesifo sohudo esisetshenziswa yi-clavulanate kakade, buphazamisa ukulala, futhi bukhombisa wena ngenkathi uzama ukuncibilikisa izinto zamathumbu emiphongolo. Yidlule ngesonto.

Ngingasebenzisa i-decongestant, i-saline rinse, noma i-steroid nasal spray ndawonye ne-Augmentin?

Yebo. Ukunisela ngosawoti kanye ne-intranasal steroid sprays kuyizinhlangano ezifanele ku-Augmentin ekuguleni kwamathumbu emiphongolo futhi ihlose ukuminyana umuthi wokubulala ibhaktheriya ongawuthinti. I-decongestants yomlomo inobufakazi obuthambile futhi kufanele ibe yiminyaka embalwa kuphela, ikakhulukazi uma unobushukela obuphezulu. Izitshalo ze-decongestant ezibhekene nomphumela akufanele zidlule iminyaka emithathu ngenxa yokuminyana okubuyayo.

Isitatimende: Lesi sihloko singeyezinjongo zokwazisa kuphela futhi akufanele sibonakale njengeseluleko sezokwelapha. Njalo thintana nochwepheshe wezempilo onamakhono ukuze uthole izinqumo zokuxilongwa nokwelashwa. Uma ubhekana nesimo esiphuthumayo sezokwelapha, shayela u-911 noma uye egumbini lezenzo eziphuthumayo eliseduze ngokushesha.