Yini i-Benzgalantamine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Benzgalantamine yimithi ehlanganisa i-galantamine ne-benzyl alcohol, eyenzelwe ukusiza abantu abanokuwohloka kwengqondo nesifo i-Alzheimer ukuthi bagcine amakhono abo okuqonda isikhathi eside. Le mithi edliwayo isebenza ngokusekela amakhemikhali obuchopho abalulekile enkumbulo namakhono okucabanga.

Uma wena noma othandekayo wakho unikezwe i-benzgalantamine, cishe ufuna imininingwane ecacile nethembekile mayelana nokuthi isebenza kanjani nokuthi yini ongayilindela. Ukuqonda imithi yakho kungakusiza ukuthi uzizwe uqiniseka ngokwengeziwe ngohambo lokwelashwa olulindele wena.

Yini i-Benzgalantamine?

I-Benzgalantamine yimithi kadokotela engaphansi kohlobo lwemithi ebizwa ngokuthi ama-cholinesterase inhibitors. Yenziwe ngqo ukwehlisa ukwehla kwe-acetylcholine, ikhemikhali yobuchopho ebalulekile enkumbulweni, ekufundeni, nakweminye imisebenzi yokuqonda.

Le mithi ihlanganisa i-galantamine hydrobromide ne-benzyl alcohol njengesilondolozi. Le nhlanganisela isiza ukuqinisekisa ukuthi imithi ihlala izinzile futhi isebenza ngenkathi inobungane ohlelweni lwakho lokugaya ukudla.

Ngokuvamile uzothola i-benzgalantamine itholakala njengesixazululo somlomo noma ithebhulethi, okwenza kube lula kubanakekeli ukuthi bayinikeze ezigulini ezingase zibe nobunzima bokugwinya amaphilisi.

Isetshenziselwani i-Benzgalantamine?

I-Benzgalantamine ikakhulukazi inikezwa ukwelapha ukuwohloka kwengqondo okungathí sina kuya kokulinganiselwe okuhlobene nesifo i-Alzheimer. Isiza ukwehlisa ukuqhubeka kwezimpawu ezinjengokulahlekelwa yinkumbulo, ukudideka, nobunzima ngemisebenzi yansuku zonke.

Udokotela wakho angase ancome le mithi uma ubona izimpawu zokuqala zokwehla kokuqonda, njengokukhohlwa izingxoxo zakamuva, ukuba nenkinga yokuthola amagama, noma ukuzabalaza ngemisebenzi ejwayelekile. Umgomo awukona ukwelapha i-Alzheimer, kodwa kunalokho ukusiza ukugcina izinga lakho lamanje lokusebenza isikhathi eside ngangokunokwenzeka.

Ngesinye isikhathi, odokotela bangase banikeze i-benzgalantamine kwezinye izinhlobo ze-dementia, nakuba isifo i-Alzheimer sisahlala siwukusetshenziswa kwayo okuyinhloko okuvunyelwe. Umhlinzeki wakho wokunakekelwa kwezempilo uzoqaphela ukuthi lo muthi ulungile yini esimweni sakho esithile.

Isebenza Kanjani I-Benzgalantamine?

I-Benzgalantamine isebenza ngokuvimba i-enzyme ebizwa nge-acetylcholinesterase, evame ukwehlisa i-acetylcholine ebuchosheni bakho. Ngokuvimbela lokhu kwehliswa, umuthi usiza ukugcina amazinga aphezulu aleli khemikhali ebalulekile yobuchopho.

Cabanga nge-acetylcholine njengomthunywa osiza amaseli obuchopho ukuthi axhumane. Esifweni i-Alzheimer, laba bathunywa bayancipha, okwenza kube nzima ukuthi ubuchopho bakho bakhe izinkumbulo ezintsha futhi zikhumbule ezikhona.

Lo muthi ubhekwa njengomuthi oqinile phakathi kokwelashwa kwe-dementia. Nakuba ingakwazi ukumisa isifo singaqhubeki, ingasiza ukunciphisa ukwehla kwengqondo futhi ikuvumele ukuthi ugcine ukuzimela isikhathi eside kunalokho ongase ukwenze ngaphandle kokwelashwa.

Kufanele Ngiyithathe Kanjani I-Benzgalantamine?

Thatha i-benzgalantamine ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile kabili ngosuku ngokudla kwakho kwasekuseni nakusihlwa. Ukuyithatha nokudla kusiza ukunciphisa isisu esibuhlungu futhi kuthuthukisa ukuthi umzimba wakho uyimunca kahle kangakanani imithi.

Uma uthatha ikhambi lomlomo, sebenzisa idivayisi yokukala eza nomuthi wakho ukuze uqinisekise ukuthi ukala ngendlela efanele. Ungalokothi usebenzise isipuni sasekhaya, njengoba lokhu kungaholela emithini engalungile engase ingasebenzi kahle noma ibangele imiphumela eminingi emibi.

Zama ukuthatha imithamo yakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo ohlelweni lwakho. Abantu abaningi bakuthola kuwusizo ukuxhumanisa izikhathi zabo zemithi nemisebenzi ejwayelekile efana nesidlo sasekuseni nesidlo sakusihlwa.

Gwinya amaphilisi wonke ngengilazi yamanzi egcwele. Ungawachobozi, uwahlafune, noma uwaphule ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze kanjalo, njengoba lokhu kungathinta indlela umuthi okhululwa ngayo emzimbeni wakho.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Benzgalantamine?

I-Benzgalantamine ngokuvamile iyindlela yokwelapha yesikhathi eside ozoqhubeka uyithatha uma nje inikeza izinzuzo futhi uyayibekezelela kahle. Abantu abaningi bayithatha izinyanga noma iminyaka, kuye ngokuthi isimo sabo siqhubeka kanjani.

Udokotela wakho uzohlola njalo ukuthi usabela kanjani emuthini, ngokuvamile njalo emavikini amathathu kuya kwayisithupha. Bazohlola ukuthi izimpawu zakho zokuqonda zizinzile, ziyathuthuka, noma ziqhubeka nokwehla naphezu kokwelashwa.

Kubalulekile ukuqonda ukuthi lo muthi usebenza kahle kakhulu uma uthathwa njalo. Ukuyeka kungazelelwe kungaholela ekwehleni okusheshayo komsebenzi wokuqonda, ngakho noma yiziphi izinguquko ohlelweni lwakho lokwelapha kufanele zixoxwe nodokotela wakho kuqala.

Yiziphi Imiphumela Eceleni ye-Benzgalantamine?

Njengayo yonke imithi, i-benzgalantamine ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi uzizwe ulungiselelwe kangcono futhi wazi ukuthi ungaxhumana nini nodokotela wakho.

Imiphumela emibi evame kakhulu ongase uyithole ngokuvamile ithambile futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi:

• Isicanucanu noma isisu esibuhlungu
• Ukuphalaza noma ukulahlekelwa isifiso sokudla
• Ukuqunjelwa noma ukuqaqamba kwesisu
• Isiyezi noma ikhanda elibuhlungu
• Ukukhathala noma ubuthakathaka
• Ukuncipha kwesisindo

Lezi zimpawu zokugaya ukudla ngokuvamile zisesikhashana futhi zingancishiswa ngokuthatha umuthi nokudla futhi uqale ngomthamo ophansi odokotela bakho abawukhulisayo kancane kancane.

Abanye abantu bangase babe nemiphumela emibi engathi sína edinga ukunakekelwa kwezokwelapha ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukwazi:

• Ubuhlungu obukhulu besisu noma ukuphalaza okuqhubekayo
• Izimpawu zokuphelelwa amanzi emzimbeni ngenxa yokuqunjelwa noma ukuphalaza
• Ukushaya kwenhliziyo okuhamba kancane noma okungajwayelekile
• Ukuphefumula kanzima noma ubuhlungu besifuba
• Isiyezi esikhulu noma ukuquleka
• Ubuthakathaka bemisipha noma ukuthuthumela

Uma uhlangabezana nanoma yiziphi zalezi zimpawu ezingathi sína, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezimo eziphuthumayo uma izimpawu zinzima.

Ubani Ongafanele Athathe I-Benzgalantamine?

I-Benzgalantamine ayifanele wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Izimo ezithile zezempilo zingenza lo muthi ungaphephile noma ungasebenzi kahle kuwe.

Akufanele uthathe i-benzgalantamine uma unezifo ezinzima zezinso noma zesibindi, njengoba umzimba wakho ungase ungakwazi ukuwusebenzisa kahle lo muthi. Abantu abanezimo ezithile zenhliziyo, ikakhulukazi ukushaya kwenhliziyo okuhamba kancane noma ukuvinjelwa okukhulu kwenhliziyo, kufanele futhi bagweme lo muthi.

Uma unomlando wezilonda zesisu, isifuba somoya, noma ukuhlaselwa, udokotela wakho uzodinga ukukala izinzuzo ngokumelene nezingozi ngokucophelela. Lezi zimo zingase zibe zimbi yi-benzgalantamine, ngakho ukubhekwa okwengeziwe kungase kudingeke.

Njalo tshela udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa nemithi etholakala ngaphandle kwe-oda kanye nezithasiselo. Eminye imithi ingase ihlangane ne-benzgalantamine, okungenzeka ibangele imiphumela emibi eyingozi noma inciphise ukusebenza kwayo.

Amagama Omkhiqizo we-Benzgalantamine

I-Benzgalantamine itholakala ngaphansi kwamagama amaningana omkhiqizo, i-Razadyne iyona engajwayelekile ukunikezwa e-United States. Ungase futhi uyibone ithengiswa njenge-Razadyne ER yezindlela zokukhishwa okwandisiwe.

Izinhlobo ze-generic ze-galantamine hydrobromide nazo ziyatholakala, eziqukethe isithako esifanayo esisebenzayo kodwa zingase zibe ngentengo ephansi. Umuthi wakho wemithi angakusiza ukuthi uqonde ukuthi ngabe uthola inguqulo yegama lomkhiqizo noma i-generic.

Noma ngabe uthola igama lomkhiqizo noma inguqulo ye-generic, umuthi kufanele usebenze ngendlela efanayo. Kodwa-ke, njalo hlola nomuthi wakho wemithi uma amaphilisi akho ebukeka ehlukile kunokujwayelekile, ngoba lokhu kusiza ukuqinisekisa ukuthi uthola umuthi ofanele.

Ezinye Izindlela ze-Benzgalantamine

Uma i-benzgalantamine ingakulungeli, eminye imithi eminingi ingasiza ekuphatheni izimpawu zesifo i-Alzheimer. Udokotela wakho angase acabangele i-donepezil (Aricept), i-rivastigmine (Exelon), noma i-memantine (Namenda) njengezinye izindlela.

Ngamunye wale mithi usebenza ngendlela ehlukile kancane futhi ingase ilungele kangcono izidingo zakho ezithile noma izimo zempilo. Abanye abantu benza ngcono ngomuthi owodwa kunomunye, ngakho-ke ukuthola okufanele ngezinye izikhathi kudinga ukubekezela nokusebenza eduze nodokotela wakho.

Izindlela ezingezona zemithi nazo zingasekela impilo yokuqonda, okuhlanganisa ukuzivocavoca njalo, ukuzibandakanya emphakathini, kanye nemisebenzi yokukhuthaza ukuqonda. Lawa maqhinga asebenza kahle kakhulu uma ehlanganiswe nokwelashwa okufanele kunokuba asetshenziswe njengokushintshwa.

Ingabe i-Benzgalantamine Ingcono Kune-Donepezil?

Kokubili i-benzgalantamine ne-donepezil ziyizindlela zokwelapha ezisebenzayo zesifo i-Alzheimer, kodwa zisebenza kancane kancane futhi zingase zilingane kangcono abantu abahlukene. Akukho muthi owodwa othi ngokujwayelekile "ungcono" kunomunye.

I-Benzgalantamine ingase ibe nezinzuzo ezithile kubantu ababhekana nezimpawu zokuziphatha ze-dementia, njengoba ngezinye izikhathi ingasiza ngokuphazamiseka noma ubudlova. Kodwa-ke, ingase ibangele ukuphazamiseka kwesisu okuningi kune-donepezil, ikakhulukazi uma uqala ukwelashwa.

Udokotela wakho uzocabangela izimpawu zakho ezithile, ezinye izimo zempilo, nokuthi uzithwala kahle kangakanani imiphumela emibi lapho ekhetha phakathi kwale mithi. Abanye abantu bangase bazuze ngisho nokuzama zombili ngezikhathi ezihlukene ukuze babone ukuthi iyiphi esebenza kangcono kubo.

Imibuzo Evame Ukubuzwa Mayelana ne-Benzgalantamine

Ingabe i-Benzgalantamine Iphephile Kubantu Abanezifo Zenhliziyo?

I-Benzgalantamine ingathinta isigqi senhliziyo, ngakho-ke abantu abanezimo zenhliziyo ezithile badinga ukuqapha okwengeziwe. Udokotela wakho cishe uzofuna ukuqapha inhliziyo yakho eduze uma unomlando wezinkinga zenhliziyo.

Uma unesilinganiso senhliziyo esihamba kancane, ukuvinjelwa kwenhliziyo, noma ezinye izimo zenhliziyo ezibalulekile, udokotela wakho angase akhethe elinye imithi noma akuqale ngomthamo ophansi kakhulu nokuqapha ngokucophelela. Ungalokothi ucabange ukuthi akuphephile ngaphandle kokuxoxa ngakho nomhlinzeki wakho wezempilo kuqala.

Kufanele ngenzeni uma ngiphuzile i-Benzgalantamine eningi ngengozi?

Uma ngengozi uphuza i-benzgalantamine eningi kunaleyo oyinikiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuphuza okuningi kungabangela imiphumela emibi eyingozi ehlanganisa isicanucanu esibi, ukuhlanza, isilinganiso senhliziyo esihamba kancane, nobuthakathaka bemisipha.

Ungalindi ukubona ukuthi ngabe izimpawu ziyavela - funa ukwelashwa ngokushesha. Gcina ibhodlela lemithi nawe ukuze abahlinzeki bezempilo bakwazi ukubona kahle ukuthi yini nokuthi ungakanani oyiphuzile.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Benzgalantamine?

Uma uphuthelwa umthamo we-benzgalantamine, uyithathe ngokushesha lapho ukhumbula, uma nje kungasondeli isikhathi somthamo wakho olandelayo. Uma sekusondele umthamo wakho olandelayo ohleliwe, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusebenzisa umhleli wamaphilisi noma ukusetha izikhumbuzi zocingo ukukusiza ukuthi uhlale emgqeni.

Ngingayeka nini ukuphuza i-Benzgalantamine?

Kufanele uyeke kuphela ukuphuza i-benzgalantamine ngaphansi kwesiqondiso sikadokotela wakho. Ukuyeka kungazelelwe kungabangela ukwehla okusheshayo komsebenzi wokuqonda, ngakho noma yisiphi isinqumo sokuyeka kufanele senziwe ngokucophelela ngaphansi kokuqondiswa kwezokwelapha.

Udokotela wakho angase ancome ukuyeka uma uhlangabezana nemiphumela emibi engabekezeleleki, uma imithi ingasanikezi izinzuzo, noma uma isimo sakho siqhubeke saya ezingeni lapho ezinye izindlela zokwelapha zingase zifaneleke khona.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Benzgalantamine?

Kungcono ukunciphisa noma ukugwema utshwala ngenkathi uthatha i-benzgalantamine, njengoba utshwala bungenza imiphumela emibi yemithi ibe yimbi futhi ingaphazamisa ukusebenza kwayo. Utshwala bungakwazi futhi ukusheshisa ukwehla kwengqondo kubantu abanokuwohloka kwengqondo.

Uma ukhetha ukuphuza ngezikhathi ezithile, xoxa ngalokhu nodokotela wakho kuqala. Bangakusiza ukuthi uqonde ukuthi yini engase iphephe esimweni sakho esithile futhi bakuqaphele nganoma yimiphumela emibi eyengeziwe.