Yebo. IMetronidazole ingadala isifo emagambeni, futhi yiyona esikhathi esiningi eyenzeka emiphumeleni emibi ku-FDA labels yayo: i-vulvovaginal candidiasis ku-5.6% weziguli ezisebenzisa i-1.3% ye-vaginal gel, kanye ne-Candida vaginitis cishe ku-10% ku-Vandazole 0.75% gel. Kuvame ukudala ukuthi izogcobhoza imvubelo eyayikhona kakade ngokuthula.

TL;DR: Izinto Ezibalulekile Okumele Uzikhumbule

  • Izimpawu zemvubelo yisona esikhathi esiningi esibhalwa njengomphumela ohlangene ku-metronidazole vaginal gel labels, ku-5.6% kuya ku-12% kuye ngomkhiqizo.
  • I-label ithi iningi lazo libangelwa ukuthi libeke obala i-Candida ekhona ezingeni eliphansi, hhayi ukucekela phansi amagciwane avikelayo.
  • Ukulunywa okusha akusona isibonakaliso sokuthi ukwelashwa kwakho kwe-BV noma i-trichomoniasis kuhlulekile.
  • Qedela i-metronidazole. Engeza i-antifungal ehlukile. Ukungeza i-metronidazole ngeke kusize.
  • Iphunga elinjengenhlanzi libonisa i-BV. Ukulunywa okubuhlungu ngaphandle kwephunga libonisa imvubelo.

Ingabe iMetronidazole Ingadala Isifo Emagambeni? Yebo, futhi Yiyona Efika Phambili Emiphumeleni Ohlangene Emabalini

Ingabe iMetronidazole ingadala isifo emagambeni? Yebo. Ezivivinyweni zezokwelapha ezingemuva kwe FDA label ye-metronidazole vaginal gel 1.3%, i-vulvovaginal candidiasis kwaba wumphumela emibi kakhulu owabikwa, ku-5.6% weziguli. I-Vandazole label yakudala ye-0.75% gel ibeka i-Candida vaginitis cishe ku-10% weziguli ngesikhathi noma ngokushesha ngemuva kokwelashwa.

Lelo Vandazole label lifaka "isifo samagciwane" ku-12% weziguli, maqondana nomphunga wesikhashana ku-7% kanye nokulunywa ku-6%. Izimpawu ezihlobene nemvubelo akusona isithasiselo kuleli khambi. Zihamba phambili ohlwini.

Inombolo eyisisekelo ethi "10%" esakazwa ezindaweni zempendulo yemithi ibuyela kulelo Vandazole label. Ezindaweni ezihlukahlukene, uhlu oluqinisile luphakathi kuka-5.6% kuya ku-12%, kuye ngomkhiqizo nokuthi imicimbi yafakwa kanjani. Futhi ngoba i-metronidazole ivamise ukunikezwa abesifazane nge-bacterial vaginosis, lo mphumela uhlangene uvame ukwenzeka ku-BV.

Incazelo Ye-label Yayo: IMetronidazole Kuvame Ukudala Ukuthi Ubonise Imvubelo Obuyitholile Kakade

Ingabe ama-antibiotics angadala isifo emagambeni? Ngokuvamile yebo, futhi indlela yakudala yaziwa kakhulu: ama-ejenti asakazeke kabanzi njengamaphénisleni, i-tetracyclines, kanye ne-quinolones anciphisa ama-Lactobacillus akha ukusekelwa futhi avumele i-Candida ukuthi ivele esikhaleni. IMetronidazole isebenza ngendlela ehlukile. Yi-nitroimidazole ehlasele amagciwane e-anaerobic kanye nama-protozoa, futhi ayisabalalisi kakhulu ama-lactobacilli.

Ngakho-ke yini ebangela u-10%? I-Vandazole label iyaziphendula yona. Ikhomba isilinganiso se-Candida vaginitis ku-known or previously unrecognized vaginal candidiasis eqala ukuba izimpawu kakhulu ngesikhathi sokwelashwa, kunokuba kube isifo esisha esivela ngokungazelelwe. Imvubelo yayikhona kakade ezingeni eliphansi, lithule. Ukukhipha ukwanda kwamagciwane kwenza ukuthi iziveze.

Lokhu kubaluleke kakhulu kunokuba kubukeke. Ukulunywa okusha ngesikhathi noma ngokushesha ngemuva kokwelashwa akusho ukuthi ukwelashwa kwakho kwe-BV noma i-trichomoniasis kuhlulekile. Yinkinga yesibili, ehlukile ehlezi phezu kokwelashwa okungenzeka ukuthi kuyasebenza. Futhi iMetronidazole ayinazo nhlobo i-antifungal activity, ngakho ukuyisebenzisa kakhulu, noma ukucela isikhathi eside, ngeke kusize ekulunyeni.

Ukushintshela Ku-vaginal Gel Akukukhiphi Kuleyo Nkinga

Uma usebenzisa i-Flagyl, isifo emagambeni sikhona engqondweni yakho ngesizathu esifanayo nasabanye abasebenzisa le gel, futhi ubungozi abuvamile ukuba buphansi emkhiqizweni wendawo. I- CDC's 2021 STI Treatment Guidelines ibala zombili njengokubaluleke kuqala kwi-BV: i-oral metronidazole 500 mg kabili ngosuku isikhathi samaviki ayisikhombisa, noma i-metronidazole vaginal gel 0.75% kanye ngosuku isikhathi samaviki amahlanu.

Nazi izinto eziningi ezizobe zingakutsheli: zonke izibalo ze-candidiasis ezishiwo ngenhla, u-5.6%, u-10%, u-12%, zivela ku-vaginal gel label. Indlela yendawo lapho izibalo ziqoshwe khona kahle, hhayi lapho ziphansi khona. Isilinganiso esifanayo se-oral Flagyl asikho njengoba kubhalwe, ngakho noma ngubani okushoyo isibalo esiqondile sabathathi bomlomo ubeke umbono.

I-Oral metronidazole isebenza emzimbeni wonke, okusho ukuthi ubungozi bayo be-candidiasis abugcini nje emgqeni wesitho sangasese. Izimpawu zomlomo nesisu ziyingxenye yale nkinga efanayo. Isikhathi sokwelashwa siyasithinta futhi: i- CDC yashintsha abesifazane abane-trichomoniasis kusuka kumthamo owodwa ongu-2 g kuya ku-500 mg kabili ngosuku isikhathi samaviki ayisikhombisa, ngoba isikhathi sokwelashwa esiningi sinciphise isilinganiso sabahlolelwa ukuthi bangene ngemvubelo ngemuva kwenyanga. Amadoda asathola umthamo owodwa. Isikhathi eside sokwelashwa, isikhathi eside sokuvezwa.

Ukulunywa Ngaphandle Kwephunga Kuyimvubelo, Iphunga Elinjengenhlanzi Lisho Ukuthi I-BV Isakhona

Ukuhlukanisa izimpawu ze-BV kusuka ezimpawini zemvubelo kuvame ukwenzeka ekhaya, futhi into eyodwa ecacile kakhulu iphunga. Iphunga libonisa i-BV. Ukulunywa okubuhlungu kubonisa imvubelo.

  • Bacterial vaginosis: ukuthulula, ukukhishwa okumhlophe okungaphandle noma okungamanzi, iphunga elinjengenhlanzi elivame ukuba libe libi ngemuva kocansi, nokulunywa okuncane noma okungekho nhlobo.
  • Isifo emagambeni: ukuthulula okumhlophe, okunamagundulu noma okufana noshizi, ukulunywa okubuhlungu esithweni sangasese, ukusha lapho chocolisa noma ocansini, futhi akukho phunga elinjengenhlanzi.
  • Zombili ngesikhathi esisodwa: ukulunywa kanye nephunga elingapheli elinjengenhlanzi. Lokho kuhlangana kuyisibonakaliso sokuba nezifo ezimbili, hhayi isifo esisodwa esizibonakalisa ngokungalindelekile.

Isikhathi sibeka isithombe kahle kakhulu. Izimpawu ze-BV ngokuvamile ziyancipha ngaphakathi kwezinsuku ezimbili kuya kwezintathu zokuqala ukusebenzisa i-metronidazole. Ngakho-ke ukulunywa okusha noma okubhebhethekayo ngemuva kosuku lwesithathu, noma esikhathini ngemuva kokuthi uqedile, kufanekisa imvubelo. Iphunga elinjengenhlanzi lisakhona ekupheleni kwenkambo libonisa i-BV engakacaciswa, okuxoxwa ngakho ngokuhlukile nodokotela wakho.

Yiba ukholwa ngemikhawulo lapha. Ukuzidwelela ngokusebenzisa izimpawu ze-BV nezemvubelo akuphelele, futhi izifundo zabathengi be-antifungal okungadingeki kwegeza zihlale zithola isilinganiso esibalulekile esilashwa ngokungafanele. Lapho izimpawu zingahambisani nekhono leyo ndlela, i-swab iyayigcina futhi ikongela isonto elingasebenzi.

Ungayeki Ukusebenzisa iMetronidazole, Phatha Imvubelo Kanye Nawo

Isifo emagambeni ngemuva kokwelashwa kwe-BV, noma ingxenye yaso, sivame ukwenzeka ngokwanele ukuthi singalindeleka. Umthetho wokuqala ungahlali njengokulindelekile: qedela i-metronidazole njengoba kunqunyiwe. Ukuyeka kusenesikhathi kuletha ingozi yokwehluleka kokwelashwa kwe-BV noma i-trichomoniasis kanye nesikhathi sesibili kamuva. Imvubelo yinkinga ehlukile edinga imithi ehlukile.

Le mithi yi-azole antifungal. Umthamo owodwa ongama-150 mg we-oral fluconazole udinga incwadi kadokotela futhi ulula. I-azole ye-intravaginal etholakala ngaphandle kokugeza njenge-miconazole noma i-clotrimazole, etholakala ngezindlela zosuku olulodwa, ezintathu, nezisikhombisa, isebenza kahle futhi igwema incwadi kadokotela. Izindlela ezinde kakhulu azilimazi kakhulu futhi ngokuvamile ziwukhetho oluhle uma usuzacelwa. Ukwelashwa kokubili i-BV nemvubelo ngesikhathi esifanayo kuyinto ejwayelekile, ngaphandle kwesidingo sokubeka eyodwa ngaphambi kokubeka enye futhi ngaphandle kokuxhumana okukuphoqa ukuthi uhlukanise i-metronidazole kusuka ku-topical azole, nakuba kufanele uqinisekise uhlelo nodokotela wakho. Uma usebenzisa i-vaginal gel, buza usokhemisi wakho ukuthi ungayihlukanisa kanjani i-gel ne-antifungal kunokuba ufake zombili ngesikhathi esisodwa.

Uma udinga ukubuyekezwa kukapreskripsheni ngokushesha, u-August unikeza i- $39 online urgent care visit lapho udokotela olinikwe ilayisense e-US abuyekeza izimpawu zakho futhi anikeze incwadi kadokotela lapho kufaneleka khona. Udokotela unquma. Ukubuka ku-inthanethi akukwazi ukwenza ukuhlolwa kwe-pelvic noma ukuqoqa i-vaginal swab, ngakho isehlo sokuqala noma izimpawu ezingahambisani nekhono lekhono zingadinga ukwelashwa okungaphakathi. Lo mbono ofanayo uhloshelwe ukwelashwa kwe-antifungal okudingeka kwegeza kwenye indawo emzimbeni.

Izimiso Zokuvimbela Eziningi Zale Nkinga Azikavivinywa, Isinyathelo Esisodwa Siyasiza Ngempela

Sesha indlela yokuvimbela isifo emagambeni ngenkathi usebenzisa i-metronidazole futhi uzothola izinhlu eziqinisekisiwe. Iqiniso elilula ukuthi akukho sikhathi sokuvimbela esinokuqinisekisa okunamandla okusekelayo. Ukunikeza ngokujwayelekile i-prophylactic antifungal kanye ne-metronidazole akusekelwa ubufakazi obuhle futhi akuyona ingxenye ye-CDC BV guidance. Imikhiqizo ye-Probiotic Lactobacillus, ngomlomo noma nge-vaginal, inedatha ayinamandla futhi ayihambisani nale ngenhloso ethile. Kuyamukeleka ukuzama. Akufanele kuthenjiswe.

Isinyathelo esinokusekelwa sangempela asithandwa. MedlinePlus iyaluleka iziguli ukuthi zitshele udokotela ngaphambi kokuqala i-metronidazole uma zinazo manje isifo semvubelo noma samagciwane. Zitshele ngaphambi komthamo wokuqala, hhayi ngemuva kokuba ukulunywa kuqale.

Bonisa futhi abafake amandla: isifo sikashukela noma ushukela wegazi ongagadiwe kahle, ukukhulelwa, ukunciphisa amasosha omzimba okuhlanganisa i-HIV noma ukusetshenziswa kwama-steroids, kanye nezikhathi ezithile noma eziphindaphindayo zama-antibiotics. Njengoba ama-antibiotics angadala isifo emagambeni kunoma ngubani onezici zobungozi eziningi kangaka, umlando wemvubelo ngemuva kwezikhathi ezedlule uzofanele ukubikwa ekuqaleni ukuze kube nohlelo olukhona kusengaphambili. Yeka i-douching, futhi ugweme izikhathi eziphindaphindayo ezingadingekile.

Ukulunywa Kungalinda Uhambo Oluya Esemakhemisi, Lezi Zimpawu Azikwazi

Shayela ku-911 noma uye ekamelweni eliphuthumayo manje uma:

  • Uba nokuquleka, ukwehluleka okungazelelwe noma ukuthinta ezandleni noma ezinyaweni, ukudideka, ukuhamba ngaphandle kokuzinzisa, noma ukukhuluma kancane. I-FDA labeling ixwayisa ukuthi lezi zimpawu zenhlalakahle zidinga ukuyeka ngokushesha i-metronidazole nokuhlolwa ngokushesha. Yeka imithi bese uhlolwa.
  • Unazimpawu zokuphendula okubucayi komzimba: ukuvuvukala kobuso noma komphimbo, ubunzima bokuphefumula, noma izimungumungwane ezisasazeke kulo lonke.

Bhukha ukuvakasha kungakapheli isonto elilandelayo uma:

Khuluma nodokotela ngaphambi kokuba uqale uma:

  • Uvele une isifo semvubelo noma samagciwane, uyasithola ngemuva kwezikhathi eziningi zama-antibiotics, ukhulelwe, noma unesifo sikashukela noma uhlelo lwakho lokuzivikela emzimbeni luyathinteka.

Imibuzo Evame Ukubuzwa

Ingabe iMetronidazole Ingadala i-Oral Thrush, Hhayi Vele i-Vaginal Yeast Infection?

Yebo. Kuyinto efanayo ye-Candida, nje endaweni ehlukile: amachashaza amhlophe olimini noma ezingomeni zangaphakathi zezindebe, ubuhlungu, noma ukunambitheka okungavamile. Lokhu kubaluleke kakhulu ku-oral metronidazole njenge-Flagyl, esebenza emzimbeni wonke, kunaku-vaginal gel. Izimpawu zomlomo esikhathini eside somlomo kufanele zishiwo kudokotela wakho, ngoba zidinga ifomu le-antifungal elihlukile.

Kuthatha Isikhathi Esingakanani Isifo Emagambeni Esivela KuMetronidazole Ukuba Sicace?

Izifo zemvubelo eziningi eziphathwe kahle zicaca phakathi kweviki elilodwa nezi-lidi-mbili. Kufanele ubone ukulunywa nokushisa kuncipha kungakapheli izinsuku ezimbili kuya kwezintathu zokuqala ukusebenzisa i-antifungal, noma ngisho noma inkambo ephelele ihlala izinsuku eziyisikhombisa. Uma kungabikho ukuthuthuka nhlobo ngoSuku lwesithathu, noma izimpawu zimbi kakhulu, ukwazi ukuthi kuyiphutha kungenzeka futhi udinga ukuhlolwa kunokuba uthenge ibhokisi lesibili.

Ingabe iMetronidazole Iyazivikela Ukuthi Iqhubeke Nokusebenza Ngesikhathi Sokukhulelwa Uma Ihlale Idala Izifo Emagambeni?

Ngezinye izikhathi, futhi leso sinqumo singoka dokotela wakho. I-CDC incoma ukwelashwa kwe-bacterial vaginosis ngesikhathi sokukhulelwa, ngakho ukuyeka ukwelashwa kuvame ukuba yisixazululo esingalungile. Ngokuhlangene nemvubelo, i-topical azoles ngokuvamile iyathandwa phezu kwe-oral fluconazole ngesikhathi sokukhulelwa. Ungaqali noma iyiphi ngokwakho ngenkathi ukhulelwe. Tshelani udokotela ophethe ukukhulelwa ukuthi kwenzakalani futhi nibavumele bakhethe.

Izimpawu Zami Zibuyele Inyanga Ngemuva Kokuphela KweMetronidazole. Ingabe Leyo Yimvubelo Futhi Noma I-BV?

Ngokuvamile akuyona imvubelo. Ukuphindeka kwe-BV kuvame ukubikwa cishe kuye komunye umuntu oyedwa entweni emithathu kungakapheli izinyanga ezintathu, ngakho-ke ukuphindeka kwenyanga kungenzeka kakhulu ukuthi yileyo i-BV ebuyayo kunokuba kube isifo samagciwane esisha. Hlola iphunga. Iphunga elinjengenhlanzi elinomjikelezo omncane kanye nokulunywa okuncane kubuyela kwi-BV, futhi lokho kudinga udokotela, hhayi enye i-antifungal evela emgqeni wekhemisi.

Ngidinga Ukuhlolwa, Noma Ngingakwazi Ukuyelapha Nge-OTC Antifungal?

Ngezinye izikhathi ungazilapha, kodwa izimo ezintathu zidinga i-swab kuqala: isehlo sokuqala, izimpawu ezingahambisani nendlela yakudala yokukhishwa okujiyile nokulunywa okubuhlungu, kanye nezikhathi eziphindaphindayo ngemuva kokwelashwa kwakamuva. Kulezi zimo, omunye umjikelezo we-OTC uvamise ukuthenga isikhathi. Uma uke waba nemvubelo eqinisekisiwe ngaphambili futhi lokhu kuzwakala kufana, ukuyelapha ngokwakho kuyamukeleka.

Isiphetho

Ingabe iMetronidazole Ingadala Isifo Emagambeni? Yebo, cishe ku-5.6% kuya ku-12% wabasebenzisi ngokusho kwe-FDA labels eshicilelwe nge-DailyMed. Ama-label achaza iningi lazo njengokudalula imvubelo eyayikhona kakade, okusho ukuthi isifo emagambeni ngemuva kokwelashwa kwe-BV akusona isibonakaliso sokuthi ukwelashwa kuhlulekile, futhi ukungeza i-metronidazole ngeke kusize ngoba ayinayo i-antifungal activity. Qedela inkambo, engeza i-antifungal, futhi uhlolwe uma ihlala ibuyela.

Isitatimende: Lesi sihloko sinemiphumela yokuhlinzeka kuphela futhi akubona ubuchwepheshe bezokwelapha. Njalo thintana nochwepheshe wezempilo ofanelekayo ukuthola ukwazi nokwelashwa. Uma ubhekana nesimo esiphuthumayo sezokwelapha, shayela ku-911 noma uye esibhedlela esiseduze ngokushesha.