Yini i-Ethinyl Estradiol kanye ne-Norgestimate: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Ethinyl estradiol kanye ne-norgestimate yizidakamizwa zokulawula ukuzala ezihlanganisiwe eziqukethe amahomoni amabili okwenziwa. Le mithi isebenza ngokuvimbela ukuvuthwa kwamaqanda (ukukhululwa kwamaqanda e-ovari yakho) futhi yenza kube nzima ngesidoda ukufinyelela iqanda noma iqanda elivundisiwe ukuthi linamathele esibelethweni sakho. Ingenye yezindlela ezivame kakhulu zokulawula ukuzala ngamaphilisi futhi esebenza kahle, enokusebenza ngaphezu kuka-99% uma ithathwa ngendlela efanele.

Yini i-Ethinyl Estradiol kanye ne-Norgestimate?

Le mithi ihlanganisa amahomoni amabili okwenziwa alingisa i-estrogen yakho yemvelo kanye ne-progesterone. I-Ethinyl estradiol iyindlela yokwenziwa ye-estrogen, kuyilapho i-norgestimate iyi-progestin yokwenziwa (uhlobo lwe-progesterone). Ngokuhlanganyela, la mahomoni asebenza ukuvimbela ukukhulelwa ngokuqeda ama-ovari akho ekukhululeni amaqanda njalo ngenyanga.

Le nhlanganisela iza ngesimo samaphilisi futhi ithathwa nsuku zonke. Amafomula amaningi aqukethe amaphilisi amahomoni angu-21 asebenzayo namaphilisi angu-7 angasebenzi (ama-placebos) ukukusiza ukuthi ugcine umkhuba wakho wansuku zonke. Ngesonto othatha ngalo amaphilisi angasebenzi, ngokuvamile uzoba nokopha okuhoxiswayo okulingisa isikhathi esivamile sokuya esikhathini.

Isetshenziselwani i-Ethinyl Estradiol kanye ne-Norgestimate?

Ukusetshenziswa okuyinhloko kwale mithi ukuvimbela ukukhulelwa kwabesifazane abakhetha ukulawula ukuzala ngamaphilisi. Kodwa-ke, odokotela bangase futhi bayinikele ngezimo eziningana zempilo ezinenzuzo ekulawuleni amahomoni.

Ngaphandle kokuvimbela ukukhulelwa, le nhlanganisela ingasiza ekuphatheni imijikelezo yokuya esikhathini engajwayelekile ngokuhlinzeka ngamazinga amahomoni aqhubekayo inyanga yonke. Abesifazane abaningi bathola ukuthi izikhathi zabo ziba lula futhi zivame ukuba lula lapho bethatha le mithi.

Udktora wakho angase futhi ancome le nhlanganisela yokwelapha izinduna eziphakathi nendawo kwabesifazane abaneminyaka engaphezu kwengu-15 ubudala. Amahomoni angasiza ukunciphisa ukukhiqizwa kwamafutha esikhumbeni sakho futhi anciphise ukuqubuka. Ngaphezu kwalokho, kungasiza ekuphatheni izimpawu ze-polycystic ovary syndrome (PCOS), okuhlanganisa izikhathi ezingajwayelekile nokukhula kwezinwele ngokweqile.

Abanye besifazane basebenzisa lo muthi ukunciphisa izimpawu ze-premenstrual syndrome (PMS) noma i-premenstrual dysphoric disorder (PMDD). Amazinga ahomoni aqhubekayo angasiza ukunciphisa ukuguquguquka kwemizwa, ukuqunjelwa, nobuhlungu bebele abesifazane abaningi ababa nakho ngaphambi kwesikhathi sabo.

Isebenza Kanjani I-Ethinyl Estradiol kanye ne-Norgestimate?

Le nhlanganisela isebenza ngezindlela eziningi ukuvimbela ukukhulelwa ngempumelelo. Amahomoni ikakhulukazi amisa ama-ovari akho ukuthi akhulule amaqanda ngesikhathi somjikelezo wakho wanyanga zonke, okwenza ukukhulelwa kungabi nakwenzeka.

Umuthi futhi ukhulisa amafinyila akho esitho sesitho, udale isithiyo esenza kube nzima kakhulu ukuthi isidoda sihambe futhi sifinyelele kunoma yimaphi amaqanda. Lokhu kuvikela okwengeziwe kungeza enye indlela yokusebenza kahle yokuvimbela ukukhulelwa.

Ngaphezu kwalokho, amahomoni ashintsha ukugqama kwesibeletho sakho (endometrium), okwenza kungabi maningi amathuba okuthi iqanda elivundisiwe lingahluma futhi likhule. Lesi senzo esiphindwe kathathu senza umuthi usebenze kahle kakhulu uma uthathwa ngokuqhubekayo.

Njengamandla okuvimbela ukukhulelwa, le nhlanganisela ithathwa njengena mandla amaphakathi. Isebenza kahle ngokwanele ukuvimbela ukukhulelwa ngokwethembeka kodwa ithambile ngokwanele ukuthi abesifazane abaningi bakwazi ukuyibekezelela kahle ngemiphumela emibi elawulekayo.

Kufanele Ngiyithathe Kanjani I-Ethinyl Estradiol kanye ne-Norgestimate?

Thatha iphilisi elilodwa ngesikhathi esifanayo nsuku zonke, kungakhathaliseki ukuthi uthatha amaphilisi ahomoni asebenzayo noma amaphilisi e-placebo angasebenzi. Ukuqina kubalulekile ekugcineni amazinga ahomoni aqhubekayo nokusebenza kahle okuphezulu.

Ungayithatha le mithi ngaphandle kokudla noma ngemva kokudla, kodwa ukuyithatha ngesikhathi sokudla kungasiza ukunciphisa isicanucanu uma uzwa isisu esibuhlungu. Abesifazane abaningi bathola ukuthi ukuyithatha ngesikhathi sokudla kwakusihlwa noma ngaphambi kokulala kusiza ukunciphisa noma yikuphi ukucasuka.

Qala iphakethe lakho lokuqala ngeSonto lokuqala ngemva kokuqala kwesikhathi sakho, noma ngosuku lokuqala lwesikhathi sakho uma udokotela wakho ekuncoma. Uma uqala maphakathi nomjikelezo, sebenzisa izindlela zokuvimbela ezingeziwe njengama-condom izinsuku eziyisikhombisa zokuqala.

Gwinya iphilisi lonke ngamanzi. Ungalichobozi, uhlafune, noma uliphule amaphilisi, ngoba lokhu kungathinta indlela amahomoni akhululwa ngayo emzimbeni wakho. Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho ngezindlela ezingezinye.

Ukusetha i-alamu yansuku zonke ocingweni lwakho kungakusiza ukuthi ukhumbule ukuthatha iphilisi lakho ngokuqhubekayo. Abesifazane abaningi bathola ukuthi ukulixhuma emsebenzini wansuku zonke, njengokuxubha amazinyo, kwenza kube lula ukukhumbula.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Ethinyl Estradiol kanye ne-Norgestimate?

Ungayithatha ngokuphepha le mithi uma nje udinga ukuvimbela ukukhulelwa futhi ungenazo izizathu zezokwelapha zokuyeka. Abesifazane abaningi basebenzisa izindlela zokuvimbela ukukhulelwa ngamahomoni iminyaka ngaphandle kwezinkinga.

Udokotela wakho uzofuna ukukubona njalo, ngokuvamile njalo emavikini angu-6 kuya kwangu-12, ukuze aqaphele impilo yakho futhi axoxe nganoma yiziphi izinkathazo. Lokhu kuhlolwa kusiza ukuqinisekisa ukuthi imithi iyaqhubeka nokuphepha futhi ifanele wena.

Uma usebenzisa le mithi ngenxa yezinduna noma ezinye izizathu ezingezona zokuvimbela ukukhulelwa, udokotela wakho uzoxoxa ngokuthi ukwelashwa kufanele kuqhubeke isikhathi esingakanani. Abanye besifazane babona ukuthuthuka kwezinduna phakathi nezinyanga ezi-3 kuya kwezi-6, kanti abanye bangase badinge ukwelashwa isikhathi eside.

Uma usukulungele ukuyeka ukuthatha imithi, ungenza kanjalo nganoma yisiphi isikhathi. Ukuzala kwakho kwemvelo kuvamela ukubuyela emuva ezinyangeni ezimbalwa, nakuba abanye besifazane bengase bakhulelwe ngokushesha ngemva kokuyeka.

Yiziphi Imiphumela Eceleni ye-Ethinyl Estradiol kanye ne-Norgestimate?

Abesifazane abaningi bayayithanda kahle le mithi, kodwa njengazo zonke izindlela zokwelapha ngamahomoni, ingabangela imiphumela emibi. Imiphumela eminingi emibi ithambile futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela amahomoni ezinyangeni ezimbalwa zokuqala.

Nansi imiphumela emibi evame kakhulu ongase uyithole njengoba umzimba wakho ujwayela imithi:

• Ukucasuka kwesisu noma isicanucanu, ikakhulukazi emasontweni ambalwa okuqala
• Ukuba buhlungu kwamabele noma ukuvuvukala
• Ikhanda elibuhlungu noma izinguquko ezithambile zemizwa
• Ukuphuma kwegazi noma ukubona phakathi kwemijikelezo
• Ushintsho lwesilinganiso somzimba, ngokuvamile oluncane
• Ushintsho ekuhambeni kwegazi lakho lokuya esikhathini

Le miphumela evamile ivame ukwehla kakhulu ngemva kwezinyanga ezi-2 kuya kwezi-3 zokusetshenziswa okuqhubekayo. Umzimba wakho udinga isikhathi sokujwayela amazinga amasha amahomoni.

Abanye besifazane bathola imiphumela emibi engavamile kodwa esengalawuleka engase idinge ukunakwa:

• Ukwehla kwesifiso socansi
• Ukuqunjelwa noma ukugcinwa kwamanzi
• Ushintsho esikhumbeni, okuhlanganisa nokumnyama kwezindawo ezithile
• Ushintsho ekukhishweni kwesitho sangasese sowesifazane
• Ukwanda kokuzwela elangeni
• Ukungakhululeki kwelensi yokuxhumana

Nakuba kungavamile, eminye imiphumela emibi engathi sína idinga ukunakekelwa kwezokwelapha ngokushesha futhi yenzeka ngaphansi kuka-1% wabasebenzisi:

• Amaqhubu egazi emilenzeni noma emaphashini (izimpawu zihlanganisa ubuhlungu obuzumayo emlenzeni, ubuhlungu besifuba, noma ukuphefumula kanzima)
• Izimpawu zokushaywa unhlangothi (ikhanda elibuhlungu elingazelelwe, ushintsho embonweni, noma ubuthakathaka)
• Izimpawu zokuhlaselwa yinhliziyo (ubuhlungu besifuba, ubuhlungu bomhlathi, noma ubuhlungu engalweni)
• Ubuhlungu obukhulu besisu obungabonisa izinkinga ze-gallbladder
• Ukucindezeleka okukhulu noma izinguquko zemizwa
• Ukuphuzi kwesikhumba noma amehlo (okubonisa izinkinga zesibindi)

Uma uthola noma yiziphi zalezi zimpawu ezingathi sína, funa ukunakekelwa kwezokwelapha ngokushesha. Lezi zinkinga azivamile kodwa zidinga ukwelashwa ngokushesha.

Ubani Ongafanele Athathwe I-Ethinyl Estradiol kanye ne-Norgestimate?

Izimo ezithile zezempilo zenza lo muthi ungaphephile, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuwunikeza. Ama-hormone amathuluzini okulawula ukuzala angakhuphula izingozi kwabanye besifazane.

Akufanele usebenzise lo muthi uma unanoma yiziphi zalezi zimo ezinzima:

• Umlando wamagazi, ukushaywa unhlangothi, noma ukuhlaselwa yinhliziyo
• Izifo eziqondene nokujiya kwegazi noma izinkinga zokujiya kwegazi ezizuzwe ngomlando
• Isifo sesibindi esisebenzayo noma imithombo yesibindi
• Ukuphuma kwegazi okungachazeki esithweni sangasese
• Ukukhulelwa okwaziwayo noma okusolwayo
• Umlando womdlavuza ohlobene nama-hormone (amabele, isibeletho, noma intamo yesibeletho)
• Umfutho wegazi ophezulu kakhulu
• Ikhanda elibuhlungu le-migraine eline-aura

Lezi zimo zikhuphula kakhulu ingozi yakho yezinkinga ezinzima, okwenza ezinye izindlela zokuvimbela inzalo zibe yizinqumo eziphephile kuwe.

Udokotela wakho uzophinda acabangele ngokucophelela ukunikeza lo muthi uma unezimo eziqeda ingozi:

• Ukubhema, ikakhulukazi uma uneminyaka engaphezu kwengama-35
• Isifo sikashukela esinezinkinga zemithambo yegazi
• I-cholesterol ephezulu noma ama-triglycerides
• Umlando wokucindezeleka
• Isifo se-gallbladder
• Isifo sezinso noma senhliziyo

Ukuba nalezi zimo akukuqedi ngokuzenzakalelayo, kodwa udokotela wakho uzokala izinzuzo ngokumelene nezingozi zesimo sakho esithile.

Amagama Omkhiqizo we-Ethinyl Estradiol kanye ne-Norgestimate

Le nhlanganisela ye-hormone itholakala ngaphansi kwamagama amaningi omkhiqizo e-United States. Amagama omkhiqizo ajwayelekile afaka i-Ortho Tri-Cyclen, i-Ortho Tri-Cyclen Lo, kanye ne-TriNessa.

Amanye amagama omkhiqizo ongawabona afaka i-Tri-Sprintec, i-Trinessa, kanye ne-Tri-Previfem. Lezi zinhlobo ezihlukene ziqukethe izithako ezifanayo ezisebenzayo kodwa zingase zibe nezithako ezingasebenzi ezihlukene noma izilinganiso ze-hormone ezihlukile kancane.

Izinhlobo ezivamile zitholakala kabanzi futhi ziqukethe amahomoni asebenzayo afanayo nezinhlobo ezinamagama omkhiqizo. Izinketho ezivamile zingaba ngentengo ephansi kakhulu ngenkathi zinikeza ukusebenza kahle nokuphepha okufanayo.

Uhlelo lwakho lomshuwalense lungakhetha amabhrendi athile noma izinhlobo ezivamile, ngakho-ke ukuxoxa ngezinketho nodokotela wakho kanye nosokhemisi kungakusiza ukuthi uthole inketho eshibhile kakhulu.

Ezinye izindlela ze-Ethinyl Estradiol kanye ne-Norgestimate

Uma lo muthi ungakulungele, ezinye izinketho eziningi zokulawula inzalo eziphumelelayo ziyatholakala. Udokotela wakho angakusiza ukuthi uthole enye indlela ekufanele kangcono izidingo zakho zempilo nendlela yokuphila.

Ezinye izidakamizwa zokulawula inzalo ezihlanganisiwe zisebenzisa inhlanganisela ehlukene yama-hormone engasebenza kangcono kuwe. Amaphilisi aqukethe izinhlobo ezihlukene zama-progestins, njenge-drospirenone noma i-levonorgestrel, angase abangele imiphumela emibi embalwa kwabanye besifazane.

Amaphilisi e-Progestin-only (ama-mini-pills) aphephe kakhulu kwabesifazane abangakwazi ukuthatha i-estrogen ngenxa yezimo zempilo. Lawa maphilisi aqukethe kuphela i-progesterone eyenziwe futhi awandisi ingozi yegazi.

Ezinye izinketho ezingezona zamaphilisi zihlanganisa isiqeshana sokulawula inzalo, indandatho yesitho sangasese sowesifazane, noma ama-IUD e-hormonal. Lezi zindlela ziletha ama-hormone ngendlela ehlukile futhi zingase zibe lula kwabesifazane abanobunzima bokukhumbula amaphilisi ansuku zonke.

Ezinye izindlela ezingezona ze-hormonal zihlanganisa ama-IUD e-copper, izindlela zokuvimbela njengama-diaphragms noma amakhondomu, nezindlela zokuqwashisa ngokuzala. Lezi zinketho azithinti amazinga akho e-hormone yemvelo.

Ingabe i-Ethinyl Estradiol kanye ne-Norgestimate ingcono kunezinye izidakamizwa zokulawula inzalo?

Le nhlanganisela isebenza ngempumelelo njengamanye amaphilisi okulawula inzalo uma ethathwa ngendlela efanele. “Iphayili elingcono kakhulu” lokulawula inzalo liyahlukahluka kowesifazane ngamunye ngokuya ngezici zempilo yomuntu ngamunye nokuthi umzimba wakho usabela kanjani kuma-hormone ahlukene.

Uma kuqhathaniswa namaphilisi aqukethe ama-progestin amadala, i-norgestimate ingase ibangele imiphumela emincane engemihle efana nezinguquko zemizwa noma ukukhuluphala. Abanye besifazane bathola ukuthi ibangela ama-acne amancane noma empeleni isiza ukuthuthukisa isikhumba sabo.

Kodwa-ke, amaphilisi aqukethe ama-progestin amasha njenge-drospirenone angase abe ngcono kwabesifazane abanokuvuvukala noma izinguquko zemizwa. Lezi zindlela ezintsha zenzelwe ngqo ukunciphisa imiphumela ethile engemihle.

Ukwakheka kwe-triphasic kwamaphilisi amaningi e-norgestimate (lapho amazinga e-hormone eshintsha kuyo yonke inyanga) kungase kuzizwe kungokwemvelo kwabanye besifazane. Abanye bakhetha amaphilisi e-monophasic aletha umthamo ofanayo we-hormone nsuku zonke.

Udokotela wakho uzocabangela umlando wakho wezempilo, imithi yamanje, nezintandokazi zakho siqu ukuze akuncomele inketho engcono kakhulu. Okusebenza kahle kowesifazane oyedwa kungase kungabi kuhle komunye.

Imibuzo Evame Ukubuzwa Mayelana ne-Ethinyl Estradiol kanye ne-Norgestimate

Q1. Ingabe i-Ethinyl Estradiol kanye ne-Norgestimate iphephile kwabesifazane abanesifo sikashukela?

Lo muthi ungaphephile kwabesifazane abanesifo sikashukela esilawulwa kahle, kodwa udinga ukuqapha ngokucophelela. Ama-hormone angathinta kancane amazinga kashukela egazini, ngakho-ke udokotela wakho uzofuna ukulandelela ukulawulwa kwakho kwe-glucose ngokucophelela.

Abesifazane abanesifo sikashukela abanezinkinga zemithambo yegazi (njenge-diabetic retinopathy noma i-nephropathy) babhekana nezingozi eziphakeme futhi bangase badinge ezinye izindlela zokuvimbela inzalo. Udokotela wakho uzohlola ukulawulwa kwakho kwesifo sikashukela kanye nezinkinga ngokumelene nezinzuzo zokulawula inzalo ngama-hormone.

Uma unesifo sikashukela futhi uthatha lo muthi, qapha ushukela wakho wegazi kaningi, ikakhulukazi lapho uqala. Abanye besifazane badinga ukulungiswa okuncane emithini yabo yesifo sikashukela lapho beqala ukulawula inzalo ngama-hormone.

Q2. Kufanele ngenzeni uma ngiphuzile i-Ethinyl Estradiol kanye ne-Norgestimate eningi ngengozi?

Ukuphuza amaphilisi engeziwe ngokuvamile kubangela isicanucanu, ukuhlanza, noma ukuphuma kwegazi okungajwayelekile, kodwa ukweqisa okukhulu akungenzeki. Uma ngengozi uphuza amaphilisi amaningi engeziwe, ungezwa ukugula esiswini noma uqaphele ukuphuma kwegazi okungajwayelekile.

Xhumana nodokotela wakho noma usokhemisi ukuze uthole isiqondiso uma uphuze amaphilisi amaningi engeziwe. Bangakuncoma ukuthi ngabe udinga ukunakekelwa kwezempilo noma ungaqhubeka nje nesimiso sakho esijwayelekile.

Ungazami ukuzama "ukulungisa" amaphilisi engeziwe ngokususa imithamo kamuva. Lokhu kunganciphisa ukusebenza kahle futhi kubangele ukuphuma kwegazi okungajwayelekile. Kunalokho, qhubeka uphuza amaphilisi akho njengoba kuhleliwe futhi usebenzise indlela yokuvimbela yokusekela uma unceliswe.

Q3. Kufanele Ngenzeni Uma Ngedlula Umthamo We-Ethinyl Estradiol kanye ne-Norgestimate?

Uma udlula iphilisi elilodwa elisebenzayo, liphuze ngokushesha lapho ukhumbula, noma ngabe lokho kusho ukuphuza amaphilisi amabili ngosuku olufanayo. Awudingi indlela yokuvimbela yokusekela uma udlula iphilisi elilodwa kuphela.

Ukudlula amaphilisi amabili alandelanayo asebenzayo kudinga ukuphuza amaphilisi amabili izinsuku ezimbili ukubamba. Sebenzisa indlela yokuvimbela yokusekela njengama-condom izinsuku eziyisikhombisa ngemuva kokudlula amaphilisi ukuqinisekisa ukuvikelwa.

Uma udlula amaphilisi amathathu noma ngaphezulu asebenzayo, lahla iphakethe bese uqala elisha. Sebenzisa indlela yokuvimbela yokusekela izinsuku eziyisikhombisa zokuqala zephakethe elisha. Ungahle ungabi nokuphuma kwegazi kwalelo nyanga, okujwayelekile.

Ukudlula amaphilisi angasebenzi (i-placebo) akuthinti ukusebenza kahle, kodwa ukugcina isimiso sakho sansuku zonke kusiza ukuvimbela ukukhohlwa amaphilisi asebenzayo lapho uqala kabusha.

Q4. Ngingayeka Nini Ukuphuza I-Ethinyl Estradiol kanye ne-Norgestimate?

Ungayeka ukuphuza lo muthi nganoma yisiphi isikhathi, kodwa kungcono ukuqeda iphakethe lakho lamanje ukugwema ukuphuma kwegazi okungajwayelekile. Ukuyeka phakathi nephakethe kungase kubangele ukuphuma kwegazi okungajwayelekile noma ukubona.

Ukuzala kwakho ngokuvamile kubuya phakathi nezinyanga eziyi-1 kuya kwezi-3 ngemuva kokuyeka, yize abanye besifazane bengakhulelwa ngokushesha. Sebenzisa enye indlela yokuvimbela ngokushesha uma ungalungile ukukhulelwa.

Abanye besifazane babhekana nezinguquko zesikhashana emjikelezweni wabo wokuya esikhathini ngemva kokuyeka. Ukuya kwakho esikhathini kungase kungabi njalo izinyanga ezimbalwa njengoba ukukhiqizwa kwakho kwamahomoni kwemvelo kuqala kabusha.

Uma uyeka ngenxa yemiphumela emibi, khuluma nodokotela wakho ngezindlela zokuvimbela inzalo ezingezinye. Bangakusiza ukuthi udlulele ngokuphepha kwenye inketho engasebenza kangcono kuwe.

Q5. Ngingakwazi yini ukuthatha i-Ethinyl Estradiol ne-Norgestimate ngenkathi ngincelisa?

Le nhlanganisela ayinconyelwe ngenkathi uncelisa ngoba i-estrogen inganciphisa ukukhiqizwa kobisi. Amahomoni angadlulela obisini lwebele, okungenzeka ukuthi kuthinte ingane yakho.

Amaphilisi e-progestin-only (ama-mini-pills) ayizinketho eziphephe kakhulu kumama oncancisayo. Lawa awaqukethe i-estrogen futhi maningi amathuba okuthi angawuthinti ukuhlinzekwa kobisi noma ikhwalithi.

Odokotela abaningi batusa ukulinda okungenani amasonto angu-6 ngemva kokubeletha ngaphambi kokuqala noma yikuphi ukuvimbela inzalo ngamahomoni. Lokhu kuvumela umzimba wakho ukuthi ululame futhi umise ukuncelisa uma ukhetha ukunakekela.

Uma udinga ukuvimbela inzalo ngenkathi uncelisa, xoxa ngezinketho eziphephile nodokotela wakho. Izindlela zokuvimbela, amaphilisi e-progestin-only, noma ama-IUD athile anganikeza ukuvikeleka okuphumelelayo ngaphandle kokuthinta ukuncelisa.