Cishe imizuzu engu-30 nge-naproxen sodium, cishe ihora nge-naproxen evamile. Umphumela omkhulu uvela ihora eli-1 kuya kwamane ngehora ngemuva komthamo, futhi umthamo owodwa ungase ukhulule ubuhlungu amahora angafika ku-12. Ukuthi i-naproxen ithatha isikhathi esingakanani ukusebenza kuncike kakhulu ekutheni yiluphi uhlobo olusesitokisini nokuthi ngabe uludle nokudla.

I-TL;DR: Izinto Eziyinhloko Okufanele Uzikhumbule

  • I-Naproxen sodium iqala cishe emizuzwini engu-30; i-naproxen evamile cishe ngehora eli-1.
  • Ukhululeko olukhulu lufika ihora eli-1 kuya kwamane ngehora ngemuva komthamo.
  • Umthamo owodwa uhlanganisa amahora angafika ku-12. Leyo yinto eyinhloko.
  • Ukuvuvukala komalalezi kudinga isonto noma amabili emithamo ejwayelekile.
  • Ungalokothi usebenzise amaphilisi angaphezu kuka-3 atholakala ezitolo (660 mg) emahoreni angama-24.

Kuthatha isikhathi esingakanani i-naproxen ukuba isebenze? Imvamisa imizuzu engama-30 kuye kwengama-60

Ukukhululeka kobuhlungu kungase kuqale ngemizuzu engu-30 nge-naproxen sodium nangaphakathi kwehora eli-1 nge-naproxen evamile, futhi umphumela wokunciphisa ubuhlungu uhlala amahora afinyelela ku-12. Amazinga egazi afika esiqongweni ku 1 kuye ku-2 amahora nge-naproxen sodium kanye ne-1 kuye ku-4 amahora nge-naproxen evamile. Ngakho-ke: ukuncipha kokuqala ngemizuzu engama-30 kuye kwengama-60, ukukhululeka okucacile kakhulu ngehora eli-1 kuye kwamane, ukusebenza okufika cishe emahoreni ayi-12.

Ukuvuvukala kusebenza ngesikhathi esehlukile. Uma usebenzisa i-naproxen kumalalezi kunokungaphezi okukodwa, ukuthuthuka kungase kuqale cishe ngesonto elilodwa lokusebenzisa njalo, futhi umphumela ogcwele uthathe amasonto ama-2 noma ngaphezulu. Lokho kukhula kuyinto evamile ngokuphelele emithamo yokulwa nokuvuvukala, njengoba kunjalo nakuma-antidepressants, lapho isikhathi phakphakathi komthamo wokuqala nomphumela wangempela sikhuluma ngamasonto kunamahora (bona ukuthi kuthatha isikhathi esingakanani i-Zoloft ukuba isebenze). Ukuhlola imithi yamasonto amabili ngehora lokuqala kuyisiphutha esivame kakhulu abantu abasenza ngayo ngayo.

Inzuzo yangempela ye-Naproxen ukuthi ihlala isikhathi esingakanani, hhayi ukuthi iqala ngokushesha kangakanani

Kuthatha isikhathi esingakanani i-naproxen ukuba ihlale? Cishe amahora ayi-7 kuye kwayi-12 ngokomthamo, nomphumela wokunciphisa ubuhlungu amahora afinyelela ku-12 kulo nyonyo we-FDA. I-ibuprofen, ngokuphambene nalokho, ivame ukuphinda ithathwe njalo ngamahora ama-4 kuye kwayi-6. Amaphilisi ambalwa ngosuku yinto i-naproxen eyenzayo ukuze kube nokuqala okuhamba kancane.

Okusho ukuthi ukungabekezeli kuqondiswe kimthamo ongalungile. Uma udinga ukukhululeka ngemizuzu engu-20, i-naproxen iyithuluzi elingalungile. Ukuthatha iphilisi lesibili ngehora lesi-45 akusheshisi ukuqala; kukuhambisa nje ngasebeni lokungama-24. Futhi ingozi ingeyangempela: i-naproxen iphethe i-FDA boxed warning yemicimbi emibi kakhulu ye-cardiovascular thrombotic okubalwa kuyo ukuhlaselwa yinhliziyo nesifo sohlanga, esingenzeka ngasekuqaleni kokwelashwa futhi sande ngesikhathi sokusebenzisa, kanye nokopha okukhulu kwe-gastrointestinal, izilonda, nokungena kwesilonda.

I-bottle esesandleni sakho inquma ukuthi uzolinda imizuzu engu-30 noma ihora

I-naproxen sodium ngokumelene ne-naproxen evamile ukuqala cishe imizuzu engama-30 ngokumelene nehora, ngoba itshe lesodium liyancibilika kakhulu futhi limunywa ngokushesha. Bheka ilebula: amaphilisi angama-220 mg atholakala ezitolo (i-Aleve, i-store-brand "naproxen sodium") uhlobo olusheshayo, kanti izitokisi ezifundeka njenge "naproxen" engu-250, 375 noma 500 mg, kuhlanganise ne-Naprosyn kadokotela, uhlobo olujwayelekile. I-220 mg ye-naproxen sodium ilingana cishe ne-200 mg ye-naproxen base, ngakho-ke izinombolo zamandla azikwazi ukuqhathaniswa ngqo. Amaphilisi aphuma ngesikhathi noma aqinisekiswe i-enteric enziwe ukuze akhulule kamuva futhi ayisikhetho esibi sobuhlungu obubukhali.

Isisu esingenalutho siyayisheshisa impumuzo, kodwa lesi yisivumelwano esingalungile kubantu abaningi

Ukuthatha i-naproxen esiswini esingenalutho kuyenza ingene egazini lakho ngokushesha, kanti ukudla noma ama-antacids kuyayicindezela imfuyo. Lokho kudla akushintshi ukuthi yimalini yomuthi oyomunca ekugcineni. Isikhathi kuphela esishintshayo.

Inkinga: isisu yikona kanye lapho i-naproxen yenza khona umonakalo wayo. Ilebula le-OTC likhomba ingozi enkulu yokopha uma ungaphezu kweminyaka engu-60, uke waba nesilonda noma wopha esesiswini, usebenzisa imithi yokunciphisa igazi noma ama-steroids, uphuza iziphuzo ezi-3 noma ngaphezulu zotshwala ngosuku, noma usebenzisa ngaphezu noma isikhathi eside kunokuba kushiwo. Njengeseluleko esisebenzayo kunokuba sibhalele ilebula, ingilazi enkulu yamanzi kanye nama-crackers ambalwa noma ingilazi yobisi oluncane kuyinto evumelanayo: ukubambezeleka okuncane kunesidlo esigcwele, isivikelo esithile sokwakheka kwesisu. Uma unokuvuvukala kwesisu, umlando wesilonda, noma usebenzisa ama-anticoagulants noma ama-steroids afana ne-prednisone, thatha ukudla futhi uvume isiqalo esihamba kancane.

Nge-headache yokuxineka i-naproxen iyisikhetho esihle; nge-migraine iyona ehamba kancane

I-Naproxen ye-headache kufanele iqale ukunciphisa ubuhlungu ngemizuzu engu-30 kuye kwengama-60 ngemuva komthamo we-naproxen sodium, ne ngcono kakhulu cishe ngehora eli-1 kuye kwezingu-2 lapho ifinyelela esiqongweni. Nge-headache yohlobo lokuxineka esesikhalweni sezikhathi eziningi, lokho kweluleka okude kuyinzuzo: iphilisi elilodwa livamise ukuhlanganisa usuku lonke.

I-Migraine ayinakuvuma kakhulu. Ukuqala kwayo kuhamba kancane kunalokho ukuhlaselwa yi-migraine kuvame ukukuvumela, ngakho-ke uma usebenzisa i-naproxen nge-headache yalolu hlobo, yithathe lapho uqala ukuzwa, kunokuba ulinde ubuhlungu obukhulu. Ukuhlanza nokuhlanza kungase kukuvimbele ekugcineni iphilisi. Futhi uma ama-headaches ephinda avame kakhulu kunabezinsuku ezimbili ngesonto, noma udinga i-naproxen ezinsukwini eziningi, lokho kuyingxoxo nodokotela, hhayi inkinga yemithamo. "Ubuhlungu obukhulu kakhulu empilweni yami" obungazelelwe bungene ohlwini oluphuthumayo ngezansi.

Usabuhlungu ngemuva kwamahora amabili? Impendulo cishe akukaze kube iphilisi elilodwa

Ngezinye izikhathi ungathatha i-naproxen? Iziyalezo zezitolo zivumela iphilisi eli-1 (220 mg) njalo ngamahora ayi-8 kuye kwayi-12 ngenkathi izimpawu zikhona, ngamaphilisi amabili avunyelwe kumthamo wokuqala kuphela, ungalokothi ngaphezu kwamaphilisi ama-2 kunoma yisiphi isikhathi samahora ayi-8 kuye kwayi-12 futhi ungalokothi ngaphezu kwamaphilisi ama-3 (660 mg) emahoreni angama-24. Ungangezi omunye i-NSAID.

Ngomkhetho wamahora amabili, kunezincazelo ezine kuphela ezibalulekile. Ungase usaba ufakwa, ikakhulukazi uma uwudle nokudla, kulokho ukulinda isikhathi sokulinda yikho impendulo. Kungase kube imithi engalungile kulobu buhlungu, ngoba i-naproxen ibuthakathaka ngokumelene nokushisa, ukudubula noma ukuphazamiseka kobuhlungu obusemzimbeni obusemthanjeni. Ungase ube nomthamo ongaphansi ngemikhalo kadokotela, okuyinto udokotela kuphela ongayishintsha (IMayo Clinic ichaza umthamo wokuqala ongu-1,000 mg kanye, ngobuhlungu obubukhali, kufika ku-1,500 mg ngosuku isikhathi esifushane kumalalezi ngaphansi kokuqondiswa).

Isiqondiso sesibhaliso esinjalo sibalulekile ukuba sisetshenziswe ngokoqobo: yeka bese uxhumana nodokotela uma ubuhlungu buya bubi kakhulu noma buhlala isikhathi esingaphezu kwezinsuku eziyi-10, noma uma umkhuhlane uhlala isikhathi esingaphezu kwezinsuku ezi-3.

Lapho ubuhlungu buqhubeka budlula lezo zigcini, ukuvisiwe okuku-inthanethi kwe-August okubiza u-R39 kungaba yisinyathelo esilandelayo esihlakaniphile. Udokotela ophethe ilayisense yase-US ubuyekeza izimpawu zakho futhi anqume ukuthi i-NSAID enamandla kadokotela, isigaba semithi esihlukile, noma ukuhlolwa komuntu siqu kuyalungela yini. Ayikho iresiphi eqinisekisiwe. Ukuvisiwa akukwazi ukubhekana nezimo eziphuthumayo futhi akukwazi ukubuyisela ukuhlolwa komuntu siqu noma izithombe.

Ezinye izimpawu ngenkathi ulindile azilona neze inkinga yesikhathi

Shayela u-911 noma uye egumbini lezimo eziphuthumayo manje uma:

  • Uyakhafula igazi noma okubizwa nge-coffee-ground material, uphuma indle emnyama noma enegazi, noma unokungapheli okuqinile kobuhlungu esiswini
  • Unobuhlungu besifuba, ukuphefumula kancane, ubuthakathaka obuzimele obungazelelwe noma ukukhuluma okungalungile
  • Ubuso bakho noma umphimbo wakho kuvuvukala, noma uthola izimfiva noma ubunzima bokuphefumula noma bokugwinya
  • Ukugwinya kubuhlungu noma iphilisi lizizwa libambelele emqaleni wakho noma esifubeni sakho

Bhukha ukuvisiwa kungakapheli isonto elilandelayo uma:

  • Ubuhlungu buya bubi kakhulu noma buhlale isikhathi esingaphezu kwezinsuku eziyi-10, noma umkhuhlane isikhathi esingaphezu kwezinsuku ezi-3
  • Ubuhlungu obusemzimbeni obusemthanjeni abuphenduli, noma ubuhlungu bomalalezi abubanga ngcono ngemuva kwezinsuku ezimali ezingama-2 zemithamo ejwayelekile
  • Udinga i-naproxen ezinsukwini eziningi

Khuluma nodokotela ngaphambi kokuba uqale uma:

  • Ungaphezu kweminyaka engu-60, noma uke waba nesilonda noma umlando wokuopha esiswini
  • Usebenzisa imithi yokunciphisa igazi noma ama-steroids, noma uphuza iziphuzo ezi-3 noma ngaphezulu zotshwala ngosuku
  • Unesifo senhliziyo, isifo sohlanga esedlule noma isifo sezinso, noma ukhulelwe noma uzama ukukhulelwa

Imibuzo Evame Ukubuzwa

Ngingasebenzisa i-ibuprofen ngenkathi ngilindele i-naproxen ukuba isebenze?

Cha. Zombili ziyizinto ze-NSAIDs, futhi ukuzihlanganisa kwandisa ingozi yokuopha esiswini nokukhathazeka kwezinso ngaphandle kokukhulisa kakhulu ukukhululeka kobuhlungu. Uma udinga okuthile esikhathini esiphakathi, i-acetaminophen isebenza ngendlela ehlukile futhi ngokuvamile iyengezo ephephile, yize ubheke umthamo ukuze ungaphambani nalokho okunye okusebenzisayo. Cela usokhemisi ngaphambi kokuhlanganisa noma yini ne-naproxen.

Ukuchoboza noma ukuluma iphilisi le-naproxen kuyayisheshisa ukusebenza?

Cha kakhulu, futhi ngemikhiqizo ethile kuyingozi. Amaphilisi ajwayelekile akhishwa ngokushesha, ngakho ukuchoboza akusizi kakhulu. Amaphilisi akhishwa ngesikhathi noma aqinisekiswe i-enteric yindaba ehlukile: ukugqoka kwenzelwe ukulawula lapho umuthi ukhululwa khona, futhi ukuwaphula kungakhipha umthamo ogcwele esiswini sakho ngesikhathi esisodwa. Ungalokothi uqobo noma yini enelebula elithi "delayed-release" noma "EC.".

Imikhiqizo ye-naproxen eyiketshezi noma ye-gel-capsule isebenza ngokushesha kunamaphilisi ajwayelekile?

Ngezinye izikhathi, kancane. Imithi esele isebububini igwema isinyathelo sokudilizwa, ngakho-ke ama-capsule agcwaliswe uketshezi angakushena isikhathi esincane kusukela ekuqaleni. Umphumela mncane uma ubhekwa kwezinto ezimbili ezibalulekile ngempela: ukuthi uyona ushukela noma i-naproxen evamile, nokuthi ngabe uwudle esiswini esigcwele yini. Ungakhokheli into eyengeziwe ulindele umehluko omkhulu.

Ngabe i-naproxen isiyiswe egazini lami ngemuva kokuba ubuhlungu buyeke ukukhulula?

Cha. Isikhathi sokusebenza nokususwa yizikhathi ezimbili ezihlukile, futhi abantu bavame ukuzihlanganisa. Ukukhululeka kobuhlungu kuyanyamalala kakhulu ngaphambi kokuba umuthi usuphelile, yingakho ilebula libeka isikhathi esincane samahora ayi-8 kuye kwayi-12 phakathi kwemithamo kanye nesibalo esiqinile samahora angama-24. Ukuzwa ubuhlungu buyabuya akusho ukuthi umzimba wakho usuqedile nephilisi lokugcina.

Ingane ingasebenzisa i-naproxen nge-headache?

Cha, hhayi ngaphandle kokuqondiswa kukadokotela. ilebula ye-naproxen sodium etholakala ezitolo ikhawulela ukusetshenziswa kubantu abadala kanye nezingane ezineminyaka engu-12 nangaphezulu, futhi ikutshela ukuthi ubuze udokotela kunoma ngubani omncane kunalokho. I-naproxen kadokotela isetshenziswa kwezinye izingane ngezigulo ezithile njengomalalezi wezingane, kodwa umthamo usekelwa isisindo futhi ubekwe udokotela, hhayi ngesitoko.

Isiphetho: Kuthatha isikhathi esingakanani i-naproxen ukuba isebenze imizuzu engama-30 ngehlobo lesodium, cishe ihora nge-naproxen evamile, nenhlanzeko enkulu ngehora eli-1 kuye kwamane. Kuthatha isikhathi esingakanani i-naproxen ihlala yiyona mbuzo owusizo kakhulu: amahora ayi-7 kuye kwayi-12 kusukela ephilisini elilodwa. Lindela isikhathi esibekiwe kunokuba ufune iphilisi lesibili, futhi uhlale ngaphansi kwamaphilisi ama-3 atholakala ezitolo emahoreni angama-24.

Umusho wokuzihlangula: Lesi sihloko sinemininingwane kuphela futhi akusona iseluleko sezokwelapha. Njalo thintana nomhlinzeki wezempilo oqeqeshiwe ukuze uthole ukuxilongwa nezinqumo zokwelashwa. Uma ubhekene nesimo esiphuthumayo sezokwelapha, shayela u-911 noma uye egumbini lezimo eziphuthumayo eliseduze ngaso leso sikhathi.