Yini i-Protriptyline: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Protriptyline iyikhambi elilwa nokucindezeleka le-tricyclic elisiza ukwelapha ukucindezeleka ngokulinganisela amakhemikhali athile obuchopho. Leli kilasi elidala le-antidepressants lisetshenziswe amashumi eminyaka futhi lihlala liyindlela ephumelelayo kubantu abaningi, nakuba ngokuvamile linqunyelwe lapho imithi emisha ingasebenzi kahle. Ukuqonda ukuthi i-protriptyline isebenza kanjani nokuthi yini ongayilindela kungakusiza uzizwe uqiniseka kakhulu ngohambo lwakho lokwelashwa.

Yini i-Protriptyline?

I-Protriptyline ingeyeqembu lemithi ebizwa ngokuthi ama-antidepressants e-tricyclic, asebenza ngendlela ehlukile kuma-antidepressants amasha ongase uzwe ngawo. Yathuthukiswa ngeminyaka yawo-1960 futhi inerekhodi elide lokusiza abantu ukuthi balawule ukucindezeleka ngempumelelo. Ngokungafani namanye ama-antidepressants e-tricyclic, i-protriptyline ivame ukuba yinto ekhuthazayo kunokuba ithulise, okusho ukuthi mancane amathuba okuthi ikwenze uzizwe ubuthuntu emini.

Udokotela wakho angase akhethe i-protriptyline lapho ezinye izidakamizwa ezingelaphi ukucindezeleka zingakunikezanga usizo oludingayo. Ithathwa njengokwelashwa komugqa wesibili, okusho ukuthi odokotela bavame ukuzama imithi emisha kuqala, kodwa i-protriptyline ingaba usizo ikakhulukazi ezinhlotsheni ezithile zokucindezeleka noma uma ube nemiphumela emibi evela kweminye imithi.

Isetshenziselwani i-Protriptyline?

I-Protriptyline ngokuyinhloko inqunyelwe ukwelapha ukuphazamiseka okukhulu kokucindezeleka, ukusiza ukuqeda usizi oluqhubekayo, ukungabi nathemba, nokuntula amandla okubonisa lesi simo. Udokotela wakho angase akutuse uma ubulokhu ulwa nokucindezeleka okungazange kuphendule kahle kwezinye izindlela zokwelapha noma uma udinga umuthi ongenakwenza ukozela.

Ngaphandle kokucindezeleka, odokotela ngezinye izikhathi banikeza i-protriptyline ezinye izimo, nakuba lezi zithathwa njengezinto ezisetshenziswa "ngaphandle kwelebula". Lokhu kungabandakanya izinhlobo ezithile zobuhlungu obungapheli, ikakhulukazi ubuhlungu bemizwa, noma izinkinga zokulala lapho izakhiwo zokuvuselela zomuthi zingaba usizo. Nokho, udokotela wakho uzoqaphela ngokucophelela izinzuzo nezingozi zanoma yikuphi ukusetshenziswa ngaphandle kokwelapha ukucindezeleka.

Isebenza Kanjani I-Protriptyline?

I-Protriptyline isebenza ngokwandisa amazinga amakhemikhali athile obuchopho abizwa ngokuthi ama-neurotransmitters, ikakhulukazi i-norepinephrine ne-serotonin. Cabanga ngala makhemikhali njengezithunywa ezisiza amaseli emizwa ebuchosheni bakho ukuthi axhumane ngesimo sengqondo, amandla, nokuphila kahle ngokomzwelo. Uma lawa mazinga ephansi, ungase uzwe izimpawu zokucindezeleka.

Lo muthi uthathwa njengomuthi oqinile phakathi kwama-antidepressants, kodwa usebenza kancane kunalokho ongakulindela. Ngokuvamile ngeke uzizwele izinzuzo ezigcwele amasonto angu-4 kuya kwangu-6, nakuba abanye abantu beqaphela ukuthuthuka okuncane ekulaleni noma ekudleni phakathi nesonto lokuqala noma amabili. Isimo esivuselelayo se-protriptyline sichaza ukuthi singasiza ngamandla nokugqugquzela, yingakho odokotela bevame ukuyinikeza ekuseni kunasebusuku.

Kufanele Ngiyithathe Kanjani I-Protriptyline?

Kufanele uthathe i-protriptyline ngendlela eqondile udokotela wakho ayinikezayo, ngokuvamile kanye noma kabili ngosuku ngaphandle kokudla. Odokotela abaningi batusa ukuyithatha ekuseni ngenxa yemiphumela yayo evuselelayo, nakuba abanye abantu benza kangcono ngemithamo ehlukanisiwe usuku lonke. Ukuyithatha nokudla kungasiza ekunciphiseni isisu uma uzwa noma yikuphi ukuphatheka kabi kokugaya ukudla.

Kulungile ngokuphelele ukuthatha i-protriptyline ngobisi, amanzi, noma ijusi. Akudingeki ukuthi ugweme noma yikuphi ukudla okuthile, nakuba ukunciphisa i-caffeine kungase kube yinto enhle ngoba kokubili i-protriptyline ne-caffeine kungashukumisa. Uma uyithatha kabili ngosuku, zama ukuhlukanisa imithamo ngokulinganayo futhi uthathe umthamo wakho wokugcina okungenani amahora angu-6 ngaphambi kokulala ukuze ugweme izinkinga zokulala.

Imithamo yokuqala ivamise ukuba phansi, cishe i-10-15 mg ngosuku, futhi udokotela wakho uzoqhubeka ayinyuse kancane kancane phakathi namasonto amaningana. Le ndlela eqaphelayo isiza umzimba wakho ukuthi ujwayele imithi futhi inciphisa amathuba okuba nemiphumela emibi. Ungalokothi ushintshe umthamo wakho noma uyeke ukuthatha i-protriptyline ngaphandle kokukhuluma nodokotela wakho kuqala, ngoba lokhu kungaholela ezimpawini zokuhoxiswa.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Protriptyline?

Abantu abaningi badinga ukuthatha i-protriptyline okungenani izinyanga eziyi-6 kuya ngonyaka ngemuva kokuthi izimpawu zabo zokucindezeleka zithuthuke ukuvimbela ukuphindeka. Udokotela wakho uzosebenza nawe ukunquma ubude obufanele ngokuya ngesimo sakho ngasinye, okuhlanganisa ukuthi ukucindezeleka kwakho kwakunzima kangakanani nokuthi ngabe uke waba neziqephu ezedlule.

Esiqephwini sakho sokuqala sokucindezeleka, ungase uthathe i-protriptyline izinyanga eziyi-6 kuya kweziyi-12 ngemuva kokuzwa ngcono. Uma uke waba neziqephu eziningi zokucindezeleka, udokotela wakho angase ancome ukwelashwa kwesikhathi eside, ngezinye izikhathi iminyaka eminingana. Lokhu akunjalo ngoba imithi iyiluthayo, kodwa ngoba ukucindezeleka kuvame ukubuyela uma ukwelashwa kuyeka ngokushesha kakhulu.

Isinqumo mayelana nokuthi uqhubeke isikhathi esingakanani ukwelashwa sincike ezintweni eziningi, okuhlanganisa ukuthi uqhubeke kahle kangakanani, noma yimiphi imiphumela emibi oyitholile, kanye nengozi yakho yokubuyela kokucindezeleka. Udokotela wakho uzohlola njalo nawe ukuhlola ukuthi ngabe ukuqhubeka nemithi kusengcono yini impilo yakho yengqondo.

Yiziphi Imiphumela Emibi ye-Protriptyline?

Njengazo zonke izidakamizwa, i-protriptyline ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo futhi imiphumela eminingi emibi iyathuthuka njengoba umzimba wakho ujwayela umuthi. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi uzizwe ulungiseleleke kakhulu futhi wazi ukuthi ungaxhumana nini nodokotela wakho.

Imiphumela emibi evame kakhulu ongase uyibone ihlanganisa umlomo owomile, ukuqunjelwa, umbono ongacacile, nesiyezi lapho usukuma ngokushesha. Lokhu kwenzeka ngoba i-protriptyline ithinta izamukeli ezithile emzimbeni wakho wonke, hhayi ebuchosheni bakho kuphela. Nansi imiphumela emibi ehlukaniswe ngokuthi ivamile kangakanani:

Imiphumela emibi evamile abantu abaningi abayitholayo:

• Umlomo nomphimbo owomile
• Ukuqunjelwa
• Umbono ongacacile noma ubunzima bokugxila
• Isiyezi lapho usukuma
• Ukozela noma ukukhathala (nakuba kungavamile nge-protriptyline)
• Ukuzuza isisindo ngokuhamba kwesikhathi
• Ukujuluka okwengeziwe
• Ubunzima bokuchama

Iningi lale miphumela emibi liyalawuleka futhi livame ukuthuthuka ngemva kwamasonto ambalwa okuqala ukwelashwa. Ukuphuza amanzi amaningi, ukudla ukudla okunothile nge-fiber, nokusukuma kancane kungasiza ngezinkinga eziningi zalezi.

Imiphumela emibi engavamile kodwa ebucayi okufanele iqashelwe:

• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Isiyezi esikhulu noma ukuquleka
• Ukudideka noma izinkinga zenkumbulo
• Ubunzima bokuphefumula
• Ukuqunjelwa okukhulu noma ukungakwazi ukuchama
• Ukuthuthumela noma ukuqina kwemisipha
• Ikhanda elibuhlungu elibuhlungu

Uma uthola noma iyiphi yale miphumela emibi ebucayi, xhumana nodokotela wakho ngokushesha. Akujwayelekile, kodwa kudinga ukunakekelwa kwezokwelapha.

Imiphumela emibi engavamile kodwa ebucayi edinga ukunakekelwa kwezokwelapha ngokushesha:

• Imicabango yokuzilimaza noma yokuzibulala (ikakhulukazi kubantu abadala abasebancane)
• Ukungezwani okukhulu komzimba okunezinduna, ukuvuvukala, noma ubunzima bokuphefumula
• Ukushaywa yisithuthwane
• Ushintsho olukhulu ekushayeni kwenhliziyo
• Izimpawu ze-serotonin syndrome (umkhuhlane, ukudideka, ukushaya kwenhliziyo okusheshayo, ukuqina kwemisipha)
• Ukwehla okukhulu kwengcindezi yegazi

Le miphumela emibi engavamile, kodwa ukuyazi ikusiza ukuthi ubone ukuthi nini okufanele ufune usizo lwezokwelapha ngokushesha. Udokotela wakho unqume ukuthi usebenzise i-protriptyline ngoba bakholelwa ukuthi izinzuzo zidlula lezi zingozi esimweni sakho esithile.

Ubani Ongafanele Athathe I-Protriptyline?

I-Protriptyline ayiphephile kuwo wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Izimo ezithile nezimo zenza lo muthi ube yingozi, ngakho kubalulekile ukwethembeka ngomlando wakho wezempilo.

Akufanele uthathe i-protriptyline uma uke wahlaselwa yinhliziyo muva nje, njengoba kungathinta ukushaya kwenhliziyo nengcindezi yegazi. Abantu abanezimo ezithile zenhliziyo, okuhlanganisa izinkinga ezinkulu zokushaya kwenhliziyo noma ukuvinjelwa kwenhliziyo, kufanele futhi bagweme lo muthi. Udokotela wakho cishe uzo-oda i-electrocardiogram (EKG) ngaphambi kokuqala ukwelashwa uma unokukhathazeka ngenhliziyo.

Ezinye izimo ezenza i-protriptyline ingaphephile zihlanganisa i-glaucoma enkulu, i-prostate enwetshiwe ebanga izinkinga zokuchama, nokuqunjelwa okukhulu noma ukuvinjelwa kwamathumbu. Uma uthatha imithi ebizwa ngokuthi ama-MAO inhibitors, uzodinga ukulinda okungenani izinsuku eziyi-14 ngemva kokuyeka ngaphambi kokuqala i-protriptyline, njengoba le nhlanganisela ingabangela ukusebenzisana okuyingozi.

Abantu abane-bipolar disorder badinga ukucatshangelwa okukhethekile, njengoba i-protriptyline ngezinye izikhathi ingabangela izigameko ze-manic. Uma unomlando wokushaywa yisithuthwane, izinkinga zesibindi, noma isifo sezinso, udokotela wakho angase akhethe omunye umuthi noma akuqaphele eduze uma i-protriptyline idingeka.

Amagama Omkhiqizo we-Protriptyline

I-Protriptyline itholakala ngaphansi kwamagama amaningi emikhiqizo, i-Vivactil iyona eyaziwa kakhulu e-United States. Kodwa-ke, inguqulo yegama lomkhiqizo ayivame ukunqunywa namuhla, njengoba abantu abaningi bethatha inguqulo ejwayelekile, ebizwa ngokuthi i-protriptyline hydrochloride.

I-Protriptyline ejwayelekile isebenza ngendlela efanayo nenguqulo yegama lomkhiqizo futhi iqukethe isithako esisebenzayo esifanayo. Umehluko omkhulu uvame ukuba ezithakweni ezingasebenzi, umbala, noma ukuma kwamaphilisi, kodwa ukusebenza kahle kuhlala kufana. Umshwalense wakho nawo maningi amathuba okuthi uzohlanganisa inguqulo ejwayelekile, okwenza ibe ngentengo engabizi.

Ezinye izindlela ze-Protriptyline

Uma i-protriptyline ingakulungele, ziningi ezinye izindlela ezikhona ngokuya ngezidingo zakho ezithile nezimo zempilo. Udokotela wakho angase acabangele ezinye izidambisi zokucindezeleka ze-tricyclic njenge-amitriptyline, i-nortriptyline, noma i-imipramine, ezisebenza ngendlela efanayo kodwa zinezinhlobo ezahlukene zemiphumela engemihle.

Ngokuvamile, odokotela bangase bacebise izidambisi zokucindezeleka ezintsha njenge-SSRIs (selective serotonin reuptake inhibitors) njenge-sertraline, i-fluoxetine, noma i-escitalopram. Le mithi ivame ukuba nemiphumela emibi embalwa futhi ngokuvamile kulula ukuyibekezelela, nakuba ingase ingasebenzi kahle kuwo wonke umuntu.

I-SNRIs (serotonin-norepinephrine reuptake inhibitors) njenge-venlafaxine noma i-duloxetine enye indlela, njengoba ithinta amakhemikhali obuchopho afanayo ne-protriptyline kodwa ngendlela ehlukile. Kubantu abangazange basabele emithini eminingi, odokotela bangase bacabangele ezinye izindlela ezintsha njenge-bupropion noma ngisho nokwelashwa okukhethekile.

Ingabe i-Protriptyline ingcono kune-Amitriptyline?

I-Protriptyline ne-amitriptyline zombili ziyizidambisi zokucindezeleka ze-tricyclic, kodwa zomehluko omkhulu owenza enye ibe ngcono kunenye ngokuya ngezidingo zakho ezithile. Umehluko omkhulu ukuthi i-protriptyline isebenza kakhulu futhi ayithambisi, kuyilapho i-amitriptyline ivame ukubangela ukozela okwengeziwe.

Uma ukhathazeka ngamandla aphansi, ugqozi, noma ukulala kakhulu njengengxenye yokucindezeleka kwakho, i-protriptyline ingase ibe yindlela engcono. Ngakolunye uhlangothi, uma unenkinga yokulala noma uzizwa ukhathazekile futhi uvuselekile, imiphumela ye-amitriptyline yokuthulisa ingase ibe usizo olukhulu. I-Protriptyline nayo ayivamile ukubangela ukukhuluphala okukhulu uma iqhathaniswa ne-amitriptyline.

Zombili lezi zithako zisebenza ngokulinganayo ekwelapheni ukucindezeleka, ngakho ukukhetha kuvame ukwehla emiphumeleni emibi ongase ukwazi ukuyibekezelela. Udokotela wakho uzocabangela izimpawu zakho ezithile, indlela yokuphila, nezinye izimo zezempilo lapho enquma ukuthi yikuphi ukucindezeleka kwe-tricyclic okungase kusebenze kangcono kuwe.

Imibuzo Evame Ukubuzwa Nge-Protriptyline

Ingabe i-Protriptyline Iphephile Ezinkingeni Zenhliziyo?

I-Protriptyline ingathinta isigqi senhliziyo yakho nomfutho wegazi, ngakho idinga ukucatshangelwa ngokucophelela uma unezinkinga zenhliziyo. Udokotela wakho ngokuvamile uzo-oda i-EKG ngaphambi kokuqala ukwelashwa futhi angase aqaphe inhliziyo yakho eduze, ikakhulu emasontweni ambalwa okuqala okwelashwa.

Uma unezimo zenhliziyo ezithambile ezilawulwa kahle, udokotela wakho angase akwazi ukukunika i-protriptyline ngokuqapha okuseduze. Kodwa-ke, uma uke wahlaselwa yinhliziyo yamuva, unezinkinga ezinzima zesigqi senhliziyo, noma umfutho wegazi ophezulu ongagadiwe, i-protriptyline ngokuvamile ayinconyelwe. Hlala uthembekile kudokotela wakho mayelana nanoma yiziphi izimpawu zenhliziyo noma umlando womndeni wezinkinga zenhliziyo.

Ngingenzani Uma Ngithatha I-Protriptyline Engaphezu Kwemithi Ngengozi?

Uma ngengozi uthatha i-protriptyline eningi kunaleyo ebekiwe, xhumana nodokotela wakho, usokhemisi, noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma uzizwa ulungile. Ukweqisa kwe-antidepressant ye-Tricyclic kungaba kubi futhi kungase kubeke ukuphila engozini, ikakhulu uma uthathe inani elikhulu.

Izimpawu ze-protriptyline overdose zihlanganisa ukozela okukhulu, ukudideka, ukushaya kwenhliziyo okusheshayo, ubunzima bokuphefumula, ukuquleka, noma ukulahlekelwa ukwazi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, shayela ku-911 noma uye egumbini eliphuthumayo eliseduze ngokushesha. Ungalindi ukubona ukuthi izimpawu ziyavela yini, njengoba i-protriptyline overdoses ingaba yingozi ngokushesha.

Kufanele Ngenzeni Uma Ngedlula Umthamo We-Protriptyline?

Uma udlula umthamo we-protriptyline, yithathe ngokushesha lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo owuphuthelwe bese uqhubeka neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo owuphuthelwe, njengoba lokhu kwandisa ingozi yakho yemiphumela emibi.

Uma uvame ukukhohlwa imithamo, cabangela ukusetha i-alamu yefoni noma usebenzise umhleli wamaphilisi ukukusiza ukhumbule. Ukuthatha imithamo yansuku zonke ngokuqhubekayo kubalulekile ukuze i-protriptyline isebenze ngempumelelo, ngakho zama ukuyithatha ngesikhathi esifanayo nsuku zonke. Uma udlula imithamo njalo, khuluma nodokotela wakho ngamasu okukusiza ukuthi uhlale emgwaqeni.

Ngingayeka Nini Ukuthatha I-Protriptyline?

Akufanele uyeke ukuthatha i-protriptyline ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka ngokuzumayo kungabangela izimpawu zokuhoxiswa ezihlanganisa isiyezi, isicanucanu, ikhanda, nezimpawu ezinjenge-flu. Udokotela wakho uzokusiza ukuthi unciphise kancane umthamo wakho emasontweni amaningana noma izinyanga uma sekuyisikhathi sokuyeka.

Isinqumo sokuyeka i-protriptyline sincike ekutheni ukucindezeleka kwakho kulawulwe kahle kangakanani, ukuthi sekuyisikhathi esingakanani uyithatha, kanye nengozi yakho yokubuya kokucindezeleka. Odokotela abaningi batusa ukuqhubeka nokwelashwa okungenani izinyanga eziyisi-6 ngemuva kokuthi izimpawu zakho zithuthuke ukuvimbela ukuphindeka. Abanye abantu badinga ukwelashwa kwesikhathi eside, ikakhulukazi uma beke baba neziqephu eziningi zokucindezeleka.

Ngingakwazi Ukuphuza Utywala Ngenkathi Ngithatha I-Protriptyline?

Kungcono ukugwema utshwala ngenkathi uthatha i-protriptyline, njengoba le nhlanganisela ingakhuphula ukozela, isiyezi, futhi yonakalise ukucabanga kwakho nokuxhumana kwakho. Utshwala bungase futhi benze ngcono izimpawu zokucindezeleka futhi ziphazamise ukusebenza kahle komuthi.

Uma ukhetha ukuphuza ngezikhathi ezithile, zinciphise ezinqeni ezincane futhi uqaphele ukuthi uzizwa kanjani. Ungalokothi uphuze utshwala uma usuvele unemiphumela emibi evela ku-protriptyline, futhi gwema ukushayela noma ukusebenzisa imishini ngemva kokuphuza. Uma ulwa nokusebenzisa utshwala, qiniseka ukuthi uxoxa lokhu nodokotela wakho, njengoba kuyingxenye ebalulekile yohlelo lwakho lokwelapha olujwayelekile.