Yini i-Sildenafil: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Sildenafil iyimithi kadokotela esiza ukwelapha ukungasebenzi kahle kwe-erectile (ED) kanye ne-pulmonary arterial hypertension (PAH). Ungase yazi kangcono ngegama layo lomkhiqizo elithi Viagra le-ED noma i-Revatio ye-PAH. Le mithi isebenza ngokukhulula imithambo yegazi futhi ithuthukise ukugeleza kwegazi ezindaweni ezithile zomzimba wakho, ikusize ukuthi uzuze imiphumela udokotela wakho ayikunike yona.

Yini i-Sildenafil?

I-Sildenafil ingeyodwa yezinhlobo zemithi ebizwa ngokuthi i-phosphodiesterase type 5 (PDE5) inhibitors. Cabanga ngayo njengokhiye ovula ukugeleza kwegazi okungcono emzimbeni wakho. Le mithi yaqala ukuthuthukiswa ukwelapha izimo zenhliziyo, kodwa abacwaningi bathola ukuthi inemiphumela emangalisayo ekusebenzeni kwe-erectile ngesikhathi sokuhlolwa komtholampilo.

Lokhu kutholakele kuholele komunye wemithi eyaziwa kakhulu empilweni yezocansi yamadoda. Isithako esifanayo esisebenzayo esisiza ngokungasebenzi kahle kwe-erectile sibuye sibe ngempumelelo ezimweni ezithile zenhliziyo namaphaphu. Udokotela wakho unikeza i-sildenafil ngokusekelwe ezidingweni zakho zempilo kanye nomlando wakho wezokwelapha.

Isetshenziselwani i-Sildenafil?

I-Sildenafil iphatha izimo ezimbili eziyinhloko, futhi udokotela wakho uzonquma ukuthi iyiphi esebenza esimweni sakho. Ngokungasebenzi kahle kwe-erectile, isiza amadoda ukuthi azuze futhi alondoloze ama-erections afanele umsebenzi wezocansi. Nge-pulmonary arterial hypertension, yehlisa umfutho wegazi ophezulu emithanjeni ethwala igazi lisuka enhliziyweni yakho liye emaphashini akho.

Le mithi ibhekana nalezi zimo ngokukhomba indlela efanayo yezinto eziphilayo kodwa ezingxenyeni ezihlukene zomzimba wakho. Uma une-ED, i-sildenafil yandisa ukugeleza kwegazi e-penis ngesikhathi sokuvuselelwa ngokocansi. Nge-PAH, ikhulula imithambo yegazi emaphashini akho, okwenza kube lula ukuthi inhliziyo yakho ipompe igazi ngayo.

Ngesinye isikhathi odokotela banikeza i-sildenafil kwezinye izimo lapho ukuthuthukiswa kokugeleza kwegazi kungasiza. Nokho, kufanele usebenzise lo muthi kuphela ezimweni ezitholwe ngqo udokotela wakho futhi wancoma ukwelashwa ngazo.

Isebenza Kanjani I-Sildenafil?

I-Sildenafil isebenza ngokuvimba i-enzyme ebizwa ngokuthi i-phosphodiesterase type 5 (PDE5). Le enzyme ngokuvamile ichitha into esiza imithambo yegazi ukuba iphumule futhi yande. Ngokuvimba i-PDE5, i-sildenafil ivumela imithambo yegazi ukuba ihlale iphumule isikhathi eside, ithuthukisa ukugeleza kwegazi ezindaweni eziqondiwe.

Lo muthi ubhekwa njengomuthi olukhuni ngokulinganisela futhi ngokuvamile uqala ukusebenza phakathi kwemizuzu engama-30 kuya kwengama-60 ngemva kokuwuthatha. Imiphumela ingahlala cishe amahora amane kuya kwayisithupha, nakuba lokhu kuhluka kumuntu nomuntu. Ukusabela komzimba wakho kuncike ezintweni ezinjengempilo yakho yonke, eminye imithi oyithathayo, nokuthi ngabe udle muva nje.

Kubalulekile ukuqonda ukuthi i-sildenafil ayidali ukuvuka okuzenzakalelayo ekwelashweni kwe-ED. Usadinga ukukhuthazwa ngokocansi ukuze lo muthi usebenze ngempumelelo. Ukuze uthole ukwelashwa kwe-PAH, lo muthi usebenza ngokuqhubekayo ukuze ugcine imithambo yegazi yamaphaphu yakho iphumule.

Kufanele Ngiyithathe Kanjani I-Sildenafil?

Thatha i-sildenafil ngendlela enqunywe ngayo udokotela wakho, ngokuvamile imizuzu engama-30 kuya kwengama-60 ngaphambi komsebenzi wobulili we-ED noma njengoba kuqondisiwe kwe-PAH. Ungayithatha nokudla noma ngaphandle kokudla, kodwa ukudla ukudla okukhulu noma okunamafutha amaningi ngaphambi kwesikhathi kungahle kulibazise ukuthi isebenza ngokushesha kangakanani. Ukudla okulula kuvamile ukuthi kulungile futhi ngeke kuphazamise ukusebenza komuthi.

Gwinya ithebhulethi yonke ngamanzi. Ungayigayi, ungayihlafuni, noma uyiphule ithebhulethi ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze kanjalo. Uma uyithatha nge-ED, ungathathi ngaphezu komthamo owodwa esikhathini esingamahora angama-24. Nge-PAH, ngokuvamile uzoyithatha kabili noma kathathu ngosuku njengoba kuqoshiwe.

Gwema ukuphuza utshwala obuningi uma usebenzisa i-sildenafil, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi efana nesiyezi noma umfutho wegazi ophansi. Ama-grapefruit nejusi lama-grapefruit nazo zingase zisebenzisane nomuthi, ngakho-ke kungcono ukuzigwema ngenkathi usebenzisa i-sildenafil.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Sildenafil?

Ubude besikhathi ozothatha ngaso i-sildenafil buxhomeke ngokuphelele esimweni sakho nokuthi usabela kahle kangakanani ekwelashweni. Ngokungasebenzi kahle kwe-erectile, amadoda amaningi ayithatha njengoba kudingeka ngaphambi komsebenzi wezocansi izinyanga noma iminyaka. Ngokucindezelwa kwegazi emaphapheni, cishe uzodinga ukuyithatha ngokuqhubekayo njengokwelashwa kwesikhathi eside.

Udokotela wakho uzoqapha ukuqhubeka kwakho futhi angase alungise umthamo wakho noma uhlelo lokwelashwa ngokuhamba kwesikhathi. Amanye amadoda ane-ED athola ukuthi awudingi umuthi njalo njengoba izimo zempilo ezingaphansi zithuthuka. Abanye bangase badinge ukuqhubeka beyithatha njalo ukuze bagcine umsebenzi wabo wezocansi.

Ungalokothi uyeke ukuthatha i-sildenafil ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala, ikakhulukazi uma uyithatha nge-PAH. Ukuyeka ngokuzumayo kungase kubhebhethekise isimo sakho. Umhlinzeki wakho wezempilo uzokusiza ukuthi unqume ubude bokwelashwa obulungile ngokuya ngezidingo zakho zomuntu ngamunye nesimo sempilo.

Yiziphi Imiphumela Emibi Ye-Sildenafil?

Abantu abaningi bayayibekezelela i-sildenafil kahle, kodwa njengayo yonke imithi, ingase ibangele imiphumela emibi. Izindaba ezinhle ukuthi imiphumela eminingi emibi imnene futhi yesikhashana, ngokuvamile ithuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi evame kakhulu ongase uyithole:

• Ikhanda
• Ukubomvu (ukushisa noma ukubomvu ebusweni bakho, entanyeni, noma esifubeni)
• Isisu esibuhlungu noma ukungagayeki kahle kokudla
• Ikhala elivaliwe noma eligelezayo
• Isiyezi noma ukukhathala
• Ubuhlungu emhlane noma ubuhlungu bemisipha

Le miphumela emibi ngokuvamile iyaphela emahoreni ambalwa njengoba umuthi usuka emzimbeni wakho. Ukuphuza amanzi amaningi nokuphumula kungasiza ekuphatheni lezi zimpawu.

Ezinye izimo ezingavamile kodwa ezinzima zidinga ukunakekelwa kwezempilo ngokushesha. Nakuba kungavamile, lokhu kungabandakanya ukulahlekelwa ngokuphazima kwamehlo noma ukuzwa, ubuhlungu besifuba, ukushaya kwenhliziyo okungajwayelekile, noma ukuvuka okuhlala isikhathi esingaphezu kwamahora amane. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, xhumana nodokotela wakho noma funa ukunakekelwa okuphuthumayo ngokushesha.

Ngokungavamile kakhulu, abanye abantu bangase babe nokusabela okukhulu komzimba okunezimpawu ezinjengobunzima bokuphefumula, ukuvuvukala kobuso noma umphimbo, noma ukuqubuka okukhulu. Lezi zimo zidinga ukwelashwa kwezempilo okuphuthumayo ngokushesha.

Ubani Ongafanele Athole I-Sildenafil?

I-Sildenafil ayiphephile kuwo wonke umuntu, futhi izimo ezithile zezempilo noma imithi ingakwenza kube yingozi ukuthi uyithathe. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela le mithi.

Akufanele uthathe i-sildenafil uma njengamanje usebenzisa imithi ye-nitrate yobuhlungu besifuba noma izinkinga zenhliziyo. Le nhlanganisela ingabangela ukwehla okuyingozi komfutho wegazi okungase kube yingozi ekuphileni. Imithi ejwayelekile ye-nitrate ihlanganisa i-nitroglycerin, i-isosorbide dinitrate, kanye ne-isosorbide mononitrate.

Abantu abanezimo ezithile zenhliziyo kufanele bagweme i-sildenafil noma bayisebenzise ngokucophelela okukhulu. Lokhu kufaka phakathi ukuhluleka kwenhliziyo okukhulu, ukuhlaselwa yinhliziyo noma unhlangothi olusha, umfutho wegazi ophezulu noma ophansi ongagadiwe, kanye nezinkinga ezithile zesigqi senhliziyo. Udokotela wakho wenhliziyo uzodinga ukuhlola ukuthi i-sildenafil iphephile yini esimweni sakho senhliziyo esithile.

Ezinye izimo ezingase zikuvimbele ukuthi ungathathi i-sildenafil ngokuphepha zihlanganisa isifo esibi sesibindi noma sezinso, izimo ezithile zamehlo njenge-retinitis pigmentosa, nomlando we-priapism (ukuqina okubuhlungu, okuhlala isikhathi eside). Ngaphezu kwalokho, uma unokungezwani komzimba ne-sildenafil noma yiziphi izithako zayo, akufanele uthathe le mithi.

Amagama Omkhiqizo we-Sildenafil

I-Sildenafil itholakala ngaphansi kwamagama amaningi emakethe, i-Viagra iyona eyaziwa kakhulu ekwelapheni ukungasebenzi kahle kwesitho sobulili. I-Revatio elinye igama lomkhiqizo elivunyelwe ngokukhethekile ukwelapha umfutho wegazi ophezulu emaphapheni. Zombili ziqukethe isithako esifanayo esisebenzayo kodwa zenziwe ngezindlela ezehlukene futhi zivunyelwe izimo ezehlukene.

Izinhlobo ezivamile ze-sildenafil nazo ziyatholakala futhi ziqukethe isithako esifanayo esisebenzayo njengezinhlobo zamagama omkhiqizo. Lezi zinketho ezivamile zivame ukungabizi kakhulu ngenkathi zinikeza imiphumela efanayo yokwelapha. Ikhemisi lakho lingashintsha ngokuzenzakalelayo i-sildenafil ejwayelekile ngaphandle uma udokotela wakho ekunikeza ngqo uhlobo lomkhiqizo.

Njalo hlola nomuthi wakho uma uqaphela ukuthi umuthi wakho ubukeka uhlukile ekuphindweni kwangaphambilini. Ngenkathi imithi ejwayelekile ilingana namagama omkhiqizo, ingase ibe nobunjwa obuhlukile, imibala, noma izimpawu ngokuya ngomkhiqizi.

Ezinye izindlela ze-Sildenafil

Eminye imithi eminingi ingelapha ukungasebenzi kahle kwesitho sobulili uma i-sildenafil ingasebenzi kahle kuwe noma idala imiphumela engathandeki. Ezinye izithiyo ze-PDE5 zifaka i-tadalafil (Cialis), i-vardenafil (Levitra), kanye ne-avanafil (Stendra). Ngamunye unezici ezehlukene kancane mayelana nokuthi zihlala isikhathi esingakanani nokuthi zisebenza ngokushesha kangakanani.

Endodeni engakwazi ukuthatha imithi yomlomo, ezinye izinketho zokwelapha zifaka imithi ejovwayo, amadivaysi okuvusa i-vacuum, noma izitshalo zesitho sobulili. Udokotela wakho angaxoxa ngalezi ezinye izindlela uma imithi yomlomo ingafaneleki esimweni sakho.

Ukuze uthole umfutho wegazi ophezulu emaphapheni, eminye imithi ehlukile ifaka ezinye izinhlobo ze-vasodilators, abaphikisi be-endothelin receptor, kanye ne-prostacyclin analogs. Udokotela wakho wamaphaphu uzonquma indlela engcono kakhulu yokwelapha ngokuya ngohlobo lwakho oluthile nobukhulu be-PAH.

Ingabe i-Sildenafil ingcono kune-Tadalafil?

Kokubili i-sildenafil ne-tadalafil ziyizindlela zokwelapha eziphumelelayo zokungasebenzi kahle kwe-erectile, kodwa zinezici ezehlukene ezingenza enye ifaneleke kakhulu kuwe kunenye. Umehluko omkhulu ukuthi zihlala isikhathi esingakanani emzimbeni wakho. I-Sildenafil ngokuvamile isebenza cishe amahora amane kuya kwayisithupha, kanti i-tadalafil ingahlala kuze kufike emahoreni angama-36.

Amanye amadoda akhetha i-sildenafil ngoba isitholakala isikhathi eside futhi inesithombe sokuphepha esisungulwe kahle. Abanye bakhetha i-tadalafil ngoba ubude bayo obude buvumela umsebenzi ocansi ozishintshayo. Ukukhetha kuvame ukwehla endleleni yakho yokuphila, izintandokazi, nokuthi umzimba wakho usabela kanjani emuthini ngamunye.

Udokotela wakho angakusiza ukuthi ulinganise izinzuzo nobubi benketho ngayinye ngokusekelwe esimweni sakho sempilo, eminye imithi oyithathayo, kanye nemigomo yakho yokwelashwa. Amanye amadoda azama yomibili imithi ukuze abone ukuthi iyiphi esebenza kangcono kubo ngaphambi kokuzinza ohlelweni lokwelashwa oluhlala isikhathi eside.

Imibuzo Evame Ukubuzwa Mayelana ne-Sildenafil

Ingabe i-Sildenafil iphephile ezigulini zenhliziyo?

I-Sildenafil ingaphepha emadodeni anezifo zenhliziyo, kodwa idinga ukuhlolwa ngokucophelela ngudokotela wakho. Amadoda amaningi anezimo zenhliziyo ezinzile angasebenzisa ngokuphepha i-sildenafil yokungasebenzi kahle kwe-erectile. Kodwa-ke, uma unezinkinga zenhliziyo ezinzima, umfutho wegazi ongagadiwe, noma uthatha imithi ye-nitrate, i-sildenafil ingase ingakuphepheli.

Udokotela wakho wenhliziyo uzohlola impilo yakho yenhliziyo ngaphambi kokugunyaza ukusetshenziswa kwe-sildenafil. Bangase batusa ukuhlolwa kokucindezeleka kokuzivocavoca ukuze baqinisekise ukuthi inhliziyo yakho ingakwazi ukubhekana nezidingo zomzimba zomsebenzi ocansi. Uma uzwa ubuhlungu besifuba, ukuphefumula kanzima, noma ezinye izimpawu zenhliziyo ngenkathi uthatha i-sildenafil, funa usizo lwezokwelapha ngokushesha.

Ngingenzani uma ngisebenzisa i-Sildenafil eningi ngengozi?

Uma ngabe uthatha i-sildenafil eningi ngengozi kunaleyo oyinikiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungadala ukwehla okuyingozi komfutho wegazi, isiyezi esikhulu, ukuquleka, noma ukuqina okude kwamalunga. Ungalindi ukubona ukuthi ngabe izimpawu ziyavela yini, njengoba imiphumela yokweqisa ingaba yingozi.

Ngesikhathi ulindele usizo lwezokwelapha, lala phansi futhi gwema ukuvuka ngokushesha. Ungashayeli noma usebenzise imishini. Uma uhlangabezana nezimpawu ezinzima njengobuhlungu besifuba, ubunzima bokuphefumula, noma ukulahlekelwa ukwazi, shayela izinsiza eziphuthumayo ngokushesha.

Kufanele Ngenzeni Uma Ngedlula Umthamo We-Sildenafil?

Uma uthatha i-sildenafil njengoba kudingeka ngenxa yokungasebenzi kahle kwamalunga, akukho ukukhathazeka ngokudlula umthamo ngoba uyithatha kuphela ngaphambi komsebenzi wobulili. Vele uthathe umthamo wakho olandelayo uma kudingeka, ulandela isikhathi sokulinda samahora angama-24 phakathi kwemithamo.

Ngenxa yomfutho wegazi ophezulu wamaphaphu, thatha umthamo owuphuthelwe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo owuphuthelwe. Setha izikhumbuzi ocingweni lwakho noma usebenzise umhleli wamaphilisi ukukusiza ukuthi ukhumbule isimiso sakho sokuthatha imithi esivamile.

Ngingayeka Nini Ukuthatha I-Sildenafil?

Ungayeka ukuthatha i-sildenafil ngenxa yokungasebenzi kahle kwamalunga nganoma yisiphi isikhathi, njengoba ngokuvamile isetshenziswa njengoba kudingeka kunokuba ibe ukwelashwa okuqhubekayo. Kodwa-ke, uma uyithatha ngenxa yomfutho wegazi ophezulu wamaphaphu, ungalokothi uyeke ngokuzumayo ngaphandle kwesiqondiso sikadokotela wakho, njengoba lokhu kungase kuqhubekise isimo sakho.

Xoxa nodokotela wakho uma ufuna ukuyeka ukuthatha i-sildenafil nganoma yisiphi isizathu. Bangakusiza ukuthi uqonde ukuthi kuphephile yini ukuyeka nokuthi ungase udinge yini ezinye izindlela zokwelapha. Amanye amadoda athola ukuthi adinga i-sildenafil kaningi njengoba impilo yawo yonke ithuthuka ngokushintsha indlela yokuphila noma ukwelashwa kwezimo ezingaphansi.

Ngingayithatha I-Sildenafil Neminye Imithi?

I-Sildenafil ingase ihlangane neminye imithi eminingi, ngakho-ke kubalulekile ukutshela udokotela wakho ngakho konke okuthathayo, okuhlanganisa imithi kadokotela, imithi etholakala ngaphandle kwemvume kadokotela, kanye nezithasiselo. Ukuxhumana okuyingozi kakhulu kunemithi ye-nitrate, engabangela ukwehla kwengcindezi yegazi okusongela impilo.

Eminye imithi engase ihlangane ne-sildenafil ihlanganisa imithi ethile yokwehlisa umfutho wegazi, amanye ama-antibiotics kanye nemithi elwa nesikhunta, imithi ye-HIV, kanye neminye imithi yokulawula isigqi senhliziyo. Udokotela wakho uzobuyekeza yonke imithi yakho ukuze aqinisekise ukuthi i-sildenafil iphephile ukuthi uyithathe kanye nezinye izindlela zakho zokwelapha.