Health Library Logo

Health Library

Diabetic Ketoacidosis

Overview

Diabetic ketoacidosis (DKA) is a very serious problem for people with diabetes.

DKA happens when your body doesn't make enough insulin. Insulin is like a key that unlocks your body's cells so they can use sugar for energy. Sugar is the main fuel for your muscles and other parts of your body.

Without enough insulin, your body starts using fat instead of sugar for energy. This process creates chemicals called ketones. Too many ketones build up in your blood, and that's what leads to DKA.

If you have diabetes or are at risk for it, it's important to know the signs of DKA and when to go to the hospital right away. Understanding these signs can help save your life.

Symptoms

Diabetic ketoacidosis (DKA) symptoms can appear suddenly, sometimes within a day. For some people, these symptoms are the first indication they have diabetes. These symptoms include:

  • Increased thirst: Feeling very thirsty and needing to drink a lot of fluids.
  • Frequent urination: Going to the bathroom more often than usual.
  • Nausea and vomiting: Feeling sick to your stomach and/or throwing up.
  • Stomach pain: Discomfort or pain in the abdomen.
  • Weakness and fatigue: Feeling very weak or tired.
  • Shortness of breath: Difficulty breathing, or feeling like you can't catch your breath.
  • Fruity-smelling breath: Your breath might have a sweet, fruity odor, like nail polish remover. This is a key sign.
  • Confusion or disorientation: Feeling confused or disoriented, or having trouble thinking clearly.

It's important to note that some of these symptoms can be caused by other conditions. However, there are specific signs of DKA that can be easily checked at home using blood and urine test kits:

  • High blood sugar levels: A blood sugar test will show elevated blood glucose levels. This is a significant indicator.
  • High ketone levels in the urine: A urine test will show an elevated level of ketones, which are produced by the body when it breaks down fat for energy due to a lack of insulin. This is another crucial sign.

These home tests can help confirm the presence of DKA. If you suspect you might have DKA, it's essential to seek immediate medical attention.

When to see a doctor

If you're feeling sick, stressed, or have recently been ill or injured, regularly check your blood sugar. A simple urine ketone test, available at most drugstores, can also be helpful.

See a doctor right away if:

  • You're vomiting and can't keep food or fluids down.
  • Your blood sugar is above the level your doctor recommends, and home remedies aren't working.
  • You have a moderate or high level of ketones in your urine.

Get emergency medical help if:

  • Your blood sugar stays consistently above 300 milligrams per deciliter (mg/dL) or 16.7 millimoles per liter (mmol/L) after several checks.
  • You have ketones in your urine, and you can't reach your doctor for advice.
  • You have many symptoms of diabetic ketoacidosis (DKA). These include extreme thirst, needing to urinate often, nausea and vomiting, stomach pain, feeling weak or very tired, trouble breathing, a fruity smell to your breath, and confusion.

Untreated diabetic ketoacidosis can be life-threatening. It's crucial to get help quickly if you think you might have it.

Causes

Your body needs sugar for energy. Sugar enters your cells with the help of insulin. If you don't have enough insulin, your body can't use sugar properly. This forces your body to use fat for energy instead. Breaking down fat creates acids called ketones. These ketones build up in your blood and can end up in your urine. This buildup is called diabetic ketoacidosis (DKA).

DKA often happens when:

  • You're sick: A cold, the flu, or any infection can make your body produce more hormones like adrenaline and cortisol. These hormones oppose insulin's work, sometimes leading to DKA. Common illnesses like pneumonia and infections of the urinary tract can trigger DKA.
  • Your insulin treatment isn't working correctly: Missing insulin doses, not getting enough insulin overall, or having problems with an insulin pump can all result in not having enough insulin. Any of these situations can cause DKA.

Other situations that can sometimes lead to DKA include:

  • Serious injury or emotional stress: Your body reacts to these situations in ways that can affect insulin function.
  • Heart attack or stroke: These serious medical events can disrupt the body's ability to manage blood sugar.
  • Pancreatitis (inflammation of the pancreas): The pancreas plays a crucial role in making insulin. If it's inflamed, it might not produce enough insulin.
  • Pregnancy: Hormonal changes during pregnancy can sometimes cause a temporary insulin resistance.
  • Alcohol or drug misuse (especially cocaine): These substances can interfere with the body's ability to regulate blood sugar and insulin.
  • Certain medications: Some medicines, such as corticosteroids (used for inflammation) and some water pills (diuretics), can raise blood sugar levels and make it harder for your body to use insulin effectively, potentially leading to DKA.

If you have diabetes, it's crucial to understand these potential triggers and to monitor your blood sugar closely, especially when you're sick or experiencing other stressors. If you suspect you might be developing DKA, seek immediate medical attention.

Risk factors

Diabetic ketoacidosis (DKA) is a serious complication of diabetes. It happens when your body can't use sugar (glucose) for energy and starts burning fat instead. This produces harmful acids called ketones. DKA is more likely to happen in certain situations:

  • If you have type 1 diabetes: People with type 1 diabetes don't produce insulin, a hormone needed to use glucose for energy. Without enough insulin, your body turns to burning fat, increasing the risk of DKA.

  • If you frequently skip or delay insulin doses: Insulin is crucial for managing blood sugar levels. If you're not getting enough insulin, your blood sugar can rise to dangerous levels, increasing the chances of DKA. This is especially important for people with type 1 diabetes, but can also occur in type 2 diabetes.

  • Sometimes, DKA can happen with type 2 diabetes: While less common than with type 1 diabetes, DKA can occur in people with type 2 diabetes, too. This might be due to a sudden increase in blood sugar, like from an infection or illness. Sometimes, DKA can actually be the first sign that someone has diabetes. If you're experiencing symptoms like extreme thirst, frequent urination, and nausea, it's important to see a doctor right away. These could be signs of DKA, or other serious health problems.

Complications

Diabetic ketoacidosis (DKA) is a serious condition that needs immediate medical attention. It's treated by giving fluids, important minerals (like sodium, potassium, and chloride), and insulin. Surprisingly, many of the problems that can arise during DKA treatment are actually side effects of the treatment itself.

Prevention

Preventing Diabetic Ketoacidosis and Other Diabetes Problems

Diabetic ketoacidosis (DKA) and other diabetes complications can be avoided. Here's how:

1. Control Your Diabetes Daily: Living a healthy lifestyle is key. This means regular, healthy eating and regular physical activity. It also means taking your diabetes medication (like pills or insulin) exactly as prescribed by your doctor. This is like following a recipe for your health.

2. Keep Track of Your Blood Sugar: Checking and recording your blood sugar levels is crucial. You might need to do this several times a day, possibly more if you're sick or feeling stressed. This lets you know if your blood sugar is in the right range. Think of it like a thermometer for your blood sugar. If your readings are consistently outside the target range, talk to your doctor.

3. Adjust Your Insulin as Needed: Your insulin dose might need to change based on several factors. These include your blood sugar level, what you eat, how active you are, and whether you're sick or stressed. Your doctor or a diabetes educator can help you figure out the best insulin dose for you. If your blood sugar starts to rise, follow your diabetes management plan to bring it back to the right level.

4. Check for Ketones: When you're sick or stressed, your body might produce extra ketones. This is something you need to watch out for. You can test for ketones in your urine using a simple test kit, available at most drugstores. If the ketone level is moderate or high, contact your doctor or seek emergency care immediately. If your ketone level is low, you might need more insulin.

5. Be Ready to Act Fast: If you suspect you might have diabetic ketoacidosis (DKA) – high blood sugar and high ketones in your urine – seek emergency medical attention right away. This is critical.

Diabetes complications can be frightening, but fear shouldn't stop you from taking good care of yourself. It's important to follow your diabetes treatment plan carefully and ask for help from your doctor or diabetes care team when you need it. They're there to support you.

Diagnosis

Diagnosing Diabetic Ketoacidosis (DKA) often involves a physical exam and blood tests. Sometimes, additional tests are needed to figure out what might have triggered the DKA.

Several blood tests are crucial for diagnosing DKA. These tests check for:

  • Blood sugar: If your body doesn't have enough insulin, sugar (glucose) can't get into your cells. This leads to a high blood sugar level, called hyperglycemia. As your body burns fat and protein for energy, your blood sugar keeps going up.

  • Ketones: When your body burns fat for energy, it produces acids called ketones. These ketones enter your bloodstream.

  • Blood acidity: Too many ketones in the blood make the blood too acidic. This can disrupt how your organs function.

Beyond these key blood tests, doctors might also order:

  • Blood electrolyte tests: These tests check the levels of essential minerals in your blood, like sodium, potassium, and chloride. DKA can affect these levels.

  • Urine test (urinalysis): This helps check for ketones in your urine, which provides further information about the body's acid-base balance.

  • Chest X-ray: This can help identify any lung problems that might be contributing to the DKA. For example, infections or pneumonia can sometimes be linked to DKA.

  • Electrocardiogram (ECG or EKG): An ECG measures the electrical activity of your heart. This is important because DKA can sometimes affect the heart's rhythm. Monitoring the heart's electrical activity is crucial to make sure the heart is working properly.

These tests work together to provide a complete picture of what's happening in your body and help doctors determine the best course of treatment for DKA.

Treatment

If you have diabetic ketoacidosis (DKA), you'll likely need treatment in a hospital's emergency room or be admitted to the hospital. DKA treatment typically includes these steps:

  • Replacing lost fluids: When you have DKA, your body gets rid of extra fluids through frequent urination. This needs to be replaced to help your blood sugar levels return to normal. These fluids can be given to you by mouth or directly into a vein (this is called an IV). Giving fluids through an IV is often faster and more effective.

  • Replacing electrolytes: Your blood contains important minerals, called electrolytes, like sodium, potassium, and chloride. These minerals help your body function properly, but too little insulin can cause their levels to drop in DKA. IV fluids often contain electrolytes to help your heart, muscles, and nerves work correctly again.

  • Insulin treatment: Insulin is the key to reversing DKA. It helps your body use the sugar in your blood properly. In addition to fluids and electrolytes, insulin is usually given through an IV. Once your blood sugar level gets back to a safe range (around 200 mg/dL or 11.1 mmol/L) and your blood is no longer too acidic, your doctor can often switch you back to your regular insulin treatment.

footer.address

footer.talkToAugust

footer.disclaimer

footer.madeInIndia