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What is Anabolic Steroids (Oral and Injectable): Uses, Dosage, Side Effects and More
What is Anabolic Steroids (Oral and Injectable): Uses, Dosage, Side Effects and More

Health Library

What is Anabolic Steroids (Oral and Injectable): Uses, Dosage, Side Effects and More

October 10, 2025


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Anabolic steroids are synthetic versions of testosterone, the male hormone that helps build muscle and bone strength. These medications come in two main forms: pills you swallow (oral) and injections given into muscle (parenteral). While they have legitimate medical uses, they're also commonly misused by athletes and bodybuilders seeking enhanced performance.

Understanding how these powerful hormones work in your body can help you make informed decisions about their risks and benefits. Let's explore what you need to know about anabolic steroids in a clear, supportive way.

What Are Anabolic Steroids?

Anabolic steroids are man-made chemicals that mimic testosterone in your body. They're called "anabolic" because they help build up tissues, particularly muscle and bone. The word "steroid" refers to their chemical structure, which is similar to cholesterol and other natural hormones.

These medications work by attaching to special receptors in your cells, much like a key fitting into a lock. Once attached, they signal your body to increase protein production, which leads to muscle growth and stronger bones. This process happens gradually over weeks and months, not immediately.

Your doctor might prescribe anabolic steroids for specific medical conditions where your body isn't producing enough testosterone naturally. However, the doses used for medical treatment are much lower than those often used illegally for performance enhancement.

What Are Anabolic Steroids Used For?

Doctors prescribe anabolic steroids to treat several legitimate medical conditions. The most common reason is hormone replacement therapy for men whose bodies don't make enough testosterone naturally, a condition called hypogonadism.

These medications can also help patients who are losing muscle mass due to serious illnesses. Here are the main medical uses your doctor might consider:

  • Severe weight loss from cancer, HIV/AIDS, or other chronic diseases
  • Delayed puberty in teenage boys
  • Certain types of anemia (low red blood cell count)
  • Severe burns or trauma requiring muscle rebuilding
  • Osteoporosis in some specific cases

It's important to know that using anabolic steroids without a prescription is illegal and carries serious health risks. Your doctor will only prescribe them when the medical benefits clearly outweigh the potential dangers.

How Do Anabolic Steroids Work?

Anabolic steroids are considered potent medications that create significant changes in your body's hormone balance. They work by flooding your system with synthetic testosterone, which can be 10 to 100 times stronger than what your body naturally produces.

When you take these steroids, they travel through your bloodstream and attach to testosterone receptors in your muscle cells. This triggers a cascade of events that increases protein synthesis, meaning your muscles can build and repair themselves more quickly than usual.

The steroids also affect your bone marrow, stimulating the production of red blood cells. This can improve oxygen delivery to your muscles and organs. Additionally, they can increase your appetite and help your body retain nitrogen, which is essential for muscle growth.

However, because these are such powerful hormones, they don't just affect muscles. They impact nearly every system in your body, including your liver, heart, brain, and reproductive organs.

How Should I Take Anabolic Steroids?

If your doctor prescribes anabolic steroids, they'll give you very specific instructions based on your medical condition and individual needs. The timing and method of taking them can significantly affect both their effectiveness and your safety.

For oral steroids, you'll typically take them with food to reduce stomach irritation. Your doctor might recommend taking them with milk or a meal to help your body absorb them better. The timing often depends on the specific medication, but many are taken once or twice daily.

Injectable steroids are usually given deep into a large muscle, such as your buttock or thigh. These injections are typically done every few weeks to months, depending on the specific medication. Your healthcare provider will either give you the injection or teach you how to do it safely at home.

Never change your dose or stop taking anabolic steroids suddenly without talking to your doctor first. Your body needs time to adjust when starting or stopping these powerful hormones.

How Long Should I Take Anabolic Steroids For?

The length of anabolic steroid treatment varies greatly depending on your specific medical condition and how well you respond to the medication. Some people need short-term treatment lasting a few weeks, while others require long-term therapy for chronic conditions.

For conditions like delayed puberty, treatment might last several months until normal development occurs. If you're using steroids for muscle wasting due to illness, the duration depends on your recovery progress and overall health improvement.

Your doctor will regularly monitor your progress through blood tests and physical examinations. They'll check your hormone levels, liver function, cholesterol, and other important markers to ensure the treatment remains safe and effective.

It's crucial to understand that stopping anabolic steroids abruptly can cause withdrawal symptoms and potentially dangerous hormone imbalances. Your doctor will create a tapering schedule to gradually reduce your dose when it's time to stop.

What Are the Side Effects of Anabolic Steroids?

Anabolic steroids can cause a wide range of side effects because they affect so many systems in your body. Some effects appear quickly, while others develop gradually over time with continued use.

The most common side effects you might experience include mood changes, increased appetite, and changes in your sleep patterns. Many people also notice increased body hair growth and changes in their voice. Here are the more frequent side effects:

  • Acne and oily skin
  • Mood swings, irritability, or aggression
  • Increased appetite and weight gain
  • Trouble sleeping or vivid dreams
  • Increased body hair growth
  • Changes in sexual desire

More serious side effects can develop with longer use or higher doses. These include liver problems, heart issues, and significant changes in cholesterol levels. Your doctor will monitor you closely to catch any concerning changes early.

Some side effects are more common in women, including deepening of the voice, male-pattern baldness, and irregular menstrual periods. These changes may not be reversible even after stopping the medication.

Who Should Not Take Anabolic Steroids?

Several medical conditions and situations make anabolic steroid use dangerous or inappropriate. Your doctor will carefully review your medical history before prescribing these medications to ensure they're safe for you.

People with certain heart conditions, liver disease, or prostate problems typically cannot safely use anabolic steroids. The hormones can worsen these conditions and potentially cause life-threatening complications.

You should not take anabolic steroids if you have any of these conditions:

  • Prostate cancer or enlarged prostate
  • Breast cancer (in men)
  • Severe liver disease
  • Serious heart problems
  • High levels of calcium in your blood
  • Severe kidney disease

Women who are pregnant or breastfeeding should never use anabolic steroids, as they can harm the developing baby. Additionally, men trying to father children should know that these medications can significantly reduce sperm production.

Anabolic Steroid Brand Names

Several pharmaceutical companies manufacture anabolic steroids under different brand names. These medications are tightly regulated and only available with a prescription from a licensed healthcare provider.

Some commonly prescribed brand names include Androgel and Testim for testosterone gel, Depo-Testosterone for injectable testosterone, and Oxandrin for oxandrolone tablets. Each brand may have slightly different formulations or delivery methods.

Your doctor will choose the specific brand and formulation based on your medical needs, lifestyle, and how well you tolerate the medication. Generic versions of some anabolic steroids are also available and work just as effectively as brand-name medications.

Never purchase anabolic steroids from unlicensed sources or online vendors. These products may be contaminated, counterfeit, or contain dangerous substances that could seriously harm your health.

Anabolic Steroid Alternatives

If anabolic steroids aren't appropriate for your situation, your doctor might recommend alternative treatments that can help with similar goals. These alternatives are generally safer and have fewer side effects than traditional anabolic steroids.

For muscle wasting conditions, your doctor might suggest specialized nutrition therapy, physical therapy, or other medications that can help preserve muscle mass. Growth hormone therapy is sometimes used for specific conditions, though it also carries significant risks.

Natural approaches to building muscle and strength include proper nutrition with adequate protein, regular resistance training, and ensuring you get enough sleep. These methods take longer to show results but are much safer for long-term health.

Some people consider over-the-counter supplements marketed as "natural alternatives" to steroids. However, these products are not regulated by the FDA and may contain hidden ingredients or ineffective compounds.

Are Anabolic Steroids Better Than Testosterone Replacement Therapy?

Anabolic steroids and testosterone replacement therapy (TRT) both involve supplementing your body's natural hormones, but they serve different purposes and use different approaches. Understanding these differences can help you make informed decisions about your treatment.

Testosterone replacement therapy aims to restore your hormone levels to normal ranges if your body isn't producing enough naturally. The doses used are typically much lower and designed to mimic your body's natural hormone production patterns.

Anabolic steroids, when used medically, may involve higher doses and are often prescribed for specific muscle-building or recovery purposes. However, both treatments carry similar risks and require careful medical supervision.

Your doctor will determine which approach is best based on your specific medical condition, hormone levels, and treatment goals. Neither option is inherently "better" than the other - they're simply different tools for different medical situations.

Frequently asked questions about Anabolic steroid (oral route, parenteral route)

Using anabolic steroids with diabetes requires extra caution and close monitoring by your healthcare team. These medications can affect your blood sugar levels and may make diabetes management more challenging.

Anabolic steroids can increase insulin resistance, meaning your body becomes less responsive to insulin. This can lead to higher blood sugar levels and may require adjustments to your diabetes medications. Your doctor will need to monitor your blood sugar more frequently during treatment.

If you have diabetes and your doctor recommends anabolic steroids for a medical condition, they'll work closely with you to adjust your diabetes management plan. Never start these medications without medical supervision if you have diabetes.

If you accidentally take more anabolic steroid than prescribed, contact your doctor or poison control center immediately. Taking too much can cause serious side effects and may require medical attention.

Don't try to "balance out" an overdose by skipping future doses or taking less than prescribed. This can create dangerous hormone fluctuations in your body. Instead, follow your doctor's instructions for what to do next.

Signs of taking too much might include severe mood changes, nausea, vomiting, or other unusual symptoms. Keep track of when you took the extra dose and how much, as this information will help your healthcare provider determine the best course of action.

If you miss a dose of your anabolic steroid, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular schedule.

Never double up on doses to make up for a missed one. This can cause dangerous hormone spikes and increase your risk of side effects. If you frequently forget doses, consider setting phone reminders or using a pill organizer.

For injectable anabolic steroids, contact your doctor's office if you miss an appointment. They may need to reschedule you soon to maintain consistent hormone levels in your body.

You should only stop taking anabolic steroids under your doctor's guidance. Stopping suddenly can cause withdrawal symptoms and potentially dangerous hormone imbalances that may affect your mood, energy, and overall health.

Your doctor will typically create a tapering schedule, gradually reducing your dose over several weeks or months. This gives your body time to adjust and start producing its own hormones again naturally.

The timeline for stopping depends on how long you've been taking the medication, your dose, and your individual response. Some people can stop relatively quickly, while others need a longer tapering period to avoid complications.

Yes, anabolic steroids can significantly impact fertility in both men and women. In men, these medications can reduce sperm production and may cause temporary or sometimes permanent infertility.

The steroids signal your body to stop producing its own testosterone, which can shrink the testicles and dramatically reduce sperm count. This effect is usually reversible after stopping the medication, but recovery can take months or even years.

For women, anabolic steroids can disrupt menstrual cycles and ovulation, making it difficult to conceive. If you're planning to have children, discuss these risks with your doctor before starting treatment.

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