Corticotropin (intramuscular route, subcutaneous route)
About this medication
Repository corticotropin injection is used to treat infantile spasms (seizures) in babies and children younger than 2 years of age. It is also used to treat adults with relapsing forms of multiple sclerosis. This medicine will not cure MS, but it may slow some of the disabling effects and decrease the number of flare-ups (relapses) of the disease. Repository corticotropin injection is also used to treat joint disorders (eg, psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis), autoimmune diseases (eg, systemic lupus erythematosus or SLE, polymyositis), and certain conditions of the skin (eg, erythema multiforme, Stevens-Johnson syndrome), eyes (eg, keratitis, diffuse posterior uveitis and choroiditis, optic neuritis), and lungs (eg, sarcoidosis). It is also used to treat certain allergies (eg, serum sickness) and swelling (edema) of the body. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms:
Before using this medication
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of repository corticotropin injection to treatinfantile spasmsin babies and children younger than 2 years of age. No information is available on the relationship of age to the effects of repository corticotropin injection in geriatric patients. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
How to use this medication
A nurse or other trained health professional will give you or your child this medicine in a medical facility. It is given as a shot under your skin (usually in the upper thigh, stomach, or back of the arm) or into one of your muscles. Repository corticotropin injection may sometimes be given at home to patients who do not need to be in the hospital. If you are using this medicine at home, your or your child's doctor will teach you how to prepare and inject the medicine.Be sure that you understand exactly how the medicine is prepared and injected. If your child is receiving repository corticotropin injection to treatinfantile spasms, this medicine usually comes with a Medication Guide and patient instructions. It is very important that you read and follow the instructions carefully. Be sure to ask your child's doctor about anything you do not understand. You will be shown the body areas where this shot can be given.Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems from the injections. Do not inject into red, swollen, or painful skin areas, areas with tattoos, warts, scars, birthmarks, stretch marks, or within one inch of the knee or groin area. To use theprefilled SelfJect™ injector: To use thevial: The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions. Store in the refrigerator. Do not freeze. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. You may store theprefilled SelfJect™ injectorat room temperature for up to 24 hours. Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
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