Filgrastim-txid (injection route)
Available brands
Nypozi
About this medication
Filgrastim-txid injection is used to treat neutropenia (low white blood cells) that is caused by cancer medicines. It is a synthetic (man-made) form of a substance that is naturally produced in your body called a colony stimulating factor. Filgrastim-txid helps the bone marrow to make new white blood cells. When certain cancer medicines are used to fight cancer cells, they also affect the white blood cells that fight infections. Filgrastim-txid is used to prevent or reduce the risk of infections while you are being treated with cancer medicines. This medicine is also used to help the bone marrow recover after a bone marrow transplantation, for a process called peripheral blood progenitor cell collection in cancer patients. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms:
Before using this medication
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of filgrastim-txid injection in children. Safety and efficacy have been established in children withsevere chronic neutropenia. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of filgrastim-txid injection in the elderly. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
How to use this medication
A nurse or other trained health professional may give you this medicine. It is given as a shot under your skin (usually in the upper arms, stomach, thighs, or buttocks) or through an IV catheter placed into a vein. You may be taught how to give this medicine at home. Make sure you understand all of the instructions before giving yourself an injection.Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. You will also be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems from the injections. Do not inject into skin areas that are tender, red, bruised, hard, scaly, or has scars or stretch marks. This medicine comes with patient information leaflet and patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions about: Start using the medicine 24 hours or more after you finish your chemotherapy. However, do not use it within 24 hours before you begin another chemotherapy. Allow 30 minutes for the prefilled syringe to warm up to room temperature. Do not warm using heat sources (eg, hot water, microwave, or sunlight). Check the liquid in the prefilled syringe. It should be clear and colorless to slightly yellowish. Do not use it if it is cloudy or discolored, or has flakes or particles in it. Do not use it if it is cracked or broken ,or has been dropped. Do not shake. Do not use the prefilled syringe if the needle guard has been activated. To use the prefilled syringe: The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Store in the refrigerator. Do not freeze. Do not leave this medicine in direct sunlight. You may store the medicine at room temperature for up to 24 hours. Throw this medicine away if it has been left at room temperature for longer than 24 hours. Throw away used needles in a hard, closed container where the needles cannot poke through. Keep this container away from children and pets.
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