Created at:1/13/2025
Somapacitan-beco is a long-acting growth hormone medication that helps replace the natural growth hormone your body should be making. It's given as a weekly injection under the skin, making it much more convenient than daily growth hormone shots that many people are used to.
This medication is designed to help adults whose bodies don't produce enough growth hormone naturally. Think of it as giving your body the hormonal support it needs to maintain healthy muscle mass, bone density, and overall energy levels.
Somapacitan-beco treats adult growth hormone deficiency, a condition where your pituitary gland doesn't make enough growth hormone. This can happen due to pituitary tumors, brain surgery, radiation treatment, or sometimes for unknown reasons.
When you don't have enough growth hormone as an adult, you might feel unusually tired, notice muscle weakness, or experience changes in your body composition. You may also have trouble with bone density or find that your cholesterol levels aren't where they should be.
The medication helps restore your growth hormone levels to a more normal range. This can improve your energy, help maintain muscle mass, and support better overall health and quality of life.
Somapacitan-beco works by mimicking your body's natural growth hormone, but it's been modified to last much longer in your system. While regular growth hormone injections need to be given daily, this medication only needs to be injected once a week.
The "long-acting" part comes from special changes made to the growth hormone molecule that slow down how quickly your body breaks it down. This means the medication can keep working steadily throughout the week, providing consistent hormone levels.
Once injected, the medication gradually releases active growth hormone into your bloodstream. This helps your body maintain the protein synthesis, fat metabolism, and other important processes that growth hormone normally controls.
You'll inject somapacitan-beco once a week, on the same day each week, under your skin using a pre-filled pen device. Your doctor will show you exactly how to do this safely and comfortably at home.
The injection goes into fatty tissue under your skin, typically in your thigh, upper arm, or abdomen. You should rotate injection sites each week to prevent irritation or tissue changes in any one area.
You can take this medication with or without food, as eating doesn't affect how well it works. Many people find it helpful to pick a specific day and time each week to make it part of their routine.
Before injecting, let the medication come to room temperature if it's been refrigerated. Don't shake the pen, and always check that the liquid looks clear and colorless before using it.
Most people with adult growth hormone deficiency need to take somapacitan-beco long-term, often for many years or even indefinitely. This is because the underlying condition that caused your growth hormone deficiency usually doesn't go away on its own.
Your doctor will monitor your progress with regular blood tests and check-ups to make sure the medication is working well for you. They'll adjust your dose as needed based on how you're responding and any side effects you might experience.
Some people may need to take breaks from treatment if they develop certain health conditions or need surgery. Your doctor will guide you through any necessary treatment pauses and help you restart safely when appropriate.
Like all medications, somapacitan-beco can cause side effects, though many people tolerate it well. Understanding what to expect can help you feel more confident about your treatment.
Here are the most common side effects you might experience:
These effects are usually mild and often improve as your body adjusts to the medication. Most people find they can continue treatment comfortably.
Some less common but more serious side effects need medical attention right away. You should contact your doctor if you experience severe headaches with vision changes, persistent nausea and vomiting, or signs of high blood sugar like excessive thirst and urination.
Very rarely, some people may develop antibodies against the growth hormone, which can make the medication less effective. Your doctor will monitor for this through regular blood tests.
Somapacitan-beco isn't right for everyone, and your doctor will carefully review your medical history before prescribing it. Certain conditions make this medication unsafe or less effective.
You should not take somapacitan-beco if you have active cancer or a history of certain types of tumors. Growth hormone can potentially stimulate tumor growth, so your doctor needs to be sure you're cancer-free before starting treatment.
People with severe illness, major surgery recovery, or acute respiratory failure should wait until they're stable before beginning this medication. Your body needs to be in a condition where it can handle the metabolic changes that growth hormone brings.
If you have diabetes, you can still potentially use somapacitan-beco, but you'll need closer monitoring. Growth hormone can affect blood sugar levels, so your diabetes medications might need adjustment.
Pregnancy and breastfeeding require special consideration. While there's limited data on safety during pregnancy, your doctor will weigh the benefits and risks carefully if you're planning to become pregnant or are already expecting.
Somapacitan-beco is sold under the brand name Sogroya in the United States. This is the commercial name you'll see on your prescription and medication packaging.
The medication comes in pre-filled pen injectors that are designed for easy home use. Each pen contains enough medication for multiple doses, depending on your prescribed amount.
Sogroya is manufactured by Novo Nordisk, a company that specializes in hormone therapies and has extensive experience with growth hormone medications.
If somapacitan-beco isn't the right fit for you, several other growth hormone replacement options are available. Your doctor can help you find the best alternative based on your specific needs and preferences.
Daily growth hormone injections like somatropin are the most common alternative. These include brands like Genotropin, Humatrope, and Norditropin. While they require daily injections, they've been used safely for many years.
Some people prefer daily injections because they can adjust doses more easily day by day. Others find that daily shots help them feel more in control of their treatment.
The choice between weekly and daily injections often comes down to personal preference and lifestyle factors. Your doctor will consider your schedule, comfort with injections, and how well you respond to different formulations.
Somapacitan-beco and somatropin are both effective growth hormone replacements, but they work differently in terms of convenience and dosing. The main advantage of somapacitan-beco is that you only need one injection per week instead of daily shots.
Many people find weekly injections much easier to manage and less disruptive to their daily routine. This can lead to better treatment adherence, which means better long-term results.
However, somatropin has been used for decades and has a longer track record of safety and effectiveness. Some doctors and patients prefer the ability to adjust doses more frequently with daily injections.
Both medications are equally effective at replacing growth hormone when used properly. The choice between them usually comes down to your lifestyle preferences, how well you tolerate each option, and your doctor's recommendation based on your specific situation.
Q1:Is Somapacitan-beco Safe for People with Diabetes?
Somapacitan-beco can be used in people with diabetes, but it requires careful monitoring and possibly adjusting your diabetes medications. Growth hormone can affect how your body processes sugar, potentially raising blood glucose levels.
Your doctor will likely want to check your blood sugar more frequently when you start treatment. They might need to adjust your diabetes medications or insulin doses to keep your blood sugar well-controlled.
Most people with diabetes can successfully use growth hormone replacement with proper medical supervision. The key is working closely with your healthcare team to monitor and adjust your treatment as needed.
Q2:What Should I Do If I Accidentally Use Too Much Somapacitan-beco?
If you accidentally inject more somapacitan-beco than prescribed, contact your doctor or pharmacist right away for guidance. Don't wait to see if you feel okay, as it's better to get professional advice quickly.
Taking too much growth hormone can cause symptoms like severe headaches, nausea, vomiting, fatigue, or changes in vision. These symptoms might not appear immediately, so medical monitoring is important.
Your doctor might want to see you for evaluation or have you monitor specific symptoms at home. They'll also help you figure out how to adjust your next dose safely.
Q3:What Should I Do If I Miss a Dose of Somapacitan-beco?
If you miss your weekly dose of somapacitan-beco, take it as soon as you remember, as long as it's within three days of your scheduled injection day. If more than three days have passed, skip the missed dose and take your next dose on the regularly scheduled day.
Don't take two doses at once to make up for a missed injection. This can increase your risk of side effects without providing additional benefits.
To help remember your weekly injection, many people find it helpful to set a phone reminder or mark their calendar. Some people also tie their injection day to a regular weekly activity.
Q4:When Can I Stop Taking Somapacitan-beco?
You should only stop taking somapacitan-beco under your doctor's guidance. Most people with adult growth hormone deficiency need long-term treatment because the underlying condition usually doesn't resolve on its own.
Your doctor might recommend stopping temporarily if you develop certain health conditions, need major surgery, or experience serious side effects. They'll help you understand when it's safe to resume treatment.
Some people may need to stop permanently if they develop conditions that make growth hormone unsafe, like certain types of cancer. Your doctor will monitor your health regularly to make sure continued treatment remains appropriate for you.
Q5:How Long Does It Take for Somapacitan-beco to Work?
You might start noticing some benefits from somapacitan-beco within the first few weeks of treatment, but it typically takes several months to experience the full effects. Energy levels and mood often improve first, sometimes within 2-4 weeks.
Changes in body composition, like increased muscle mass and decreased fat, usually become noticeable after 3-6 months of consistent treatment. Improvements in bone density and cholesterol levels may take even longer to detect.
Your doctor will monitor your progress through regular blood tests and physical examinations. They'll check your IGF-1 levels, which is a marker that shows how well the growth hormone is working in your body.