Created at:1/13/2025
A HIDA scan is a special imaging test that helps doctors see how well your gallbladder and bile ducts are working. Think of it as a detailed movie of your digestive system in action, specifically focusing on how bile flows from your liver through your gallbladder and into your small intestine.
This test uses a small amount of radioactive material that's completely safe and gets eliminated from your body naturally. The scan takes pictures over time to show your doctor exactly what's happening inside, helping them diagnose problems that might be causing your symptoms.
A HIDA scan, also called hepatobiliary scintigraphy, is a nuclear medicine test that tracks bile flow through your liver, gallbladder, and bile ducts. The name comes from the radioactive tracer used called hepatobiliary iminodiacetic acid.
During the test, a technologist injects a small amount of radioactive tracer into your arm vein. This tracer travels through your bloodstream to your liver, where it mixes with bile. A special camera then takes pictures as the tracer moves through your bile ducts and gallbladder, showing how well these organs are functioning.
The scan is completely painless and typically takes between one to four hours to complete. You'll lie on a table while the camera moves around you, but you won't feel the radiation or the tracer moving through your body.
Your doctor orders a HIDA scan when you have symptoms that suggest problems with your gallbladder or bile ducts. This test helps pinpoint exactly what's causing your discomfort and guides treatment decisions.
The most common reason for this scan is to check for gallbladder disease, especially when other tests like ultrasound haven't provided clear answers. Your doctor might suspect cholecystitis, which is inflammation of the gallbladder, or problems with how your gallbladder contracts and empties.
Here are the main conditions a HIDA scan can help diagnose:
Sometimes doctors also use HIDA scans to evaluate less common conditions like sphincter of Oddi dysfunction, where the muscle controlling bile flow doesn't work correctly. The test can also help assess complications after gallbladder or liver surgery.
The HIDA scan procedure is straightforward and happens in a hospital's nuclear medicine department. You'll work with specially trained technologists who will guide you through each step and answer any questions you have.
First, you'll change into a hospital gown and lie down on a padded table. A technologist will insert a small IV line into your arm, which feels like a quick pinch. Through this IV, they'll inject the radioactive tracer, which takes just a few seconds.
Here's what happens during the scan:
During the scan, you can breathe normally and even talk quietly, but you'll need to stay as still as possible. The camera doesn't touch you and makes minimal noise. Most people find the test relaxing, though lying still for extended periods can be uncomfortable.
If your gallbladder doesn't fill with tracer within the first hour, your doctor might give you morphine to help concentrate the tracer. This can extend the test time but provides more accurate results.
Proper preparation ensures your HIDA scan gives the most accurate results possible. Your doctor's office will provide specific instructions, but here are the typical requirements you'll need to follow.
The most important preparation step is fasting for at least four hours before your test. This means no food, drinks (except water), gum, or candy. Fasting helps your gallbladder concentrate bile, making it easier to see during the scan.
Before your appointment, let your medical team know about these important details:
You should continue taking your regular medications unless your doctor specifically tells you to stop. However, some medications can affect the test results, so your doctor might ask you to temporarily stop certain drugs like narcotic pain medications.
Wear comfortable, loose-fitting clothes without metal zippers or buttons near your abdomen. You'll likely change into a hospital gownway, but comfortable clothing makes the experience more pleasant.
Your HIDA scan results show how well bile flows through your liver, gallbladder, and bile ducts. A nuclear medicine specialist called a radiologist will analyze your images and send a detailed report to your doctor.
Normal results show the tracer moving smoothly from your liver into your gallbladder within 30-60 minutes. Your gallbladder should fill completely and then empty at least 35-40% of its contents when stimulated with CCK medication.
Here's what different results typically mean:
Your ejection fraction is a key measurement that shows what percentage of bile your gallbladder empties. A normal ejection fraction is typically 35% or higher, though some labs use 40% as their cutoff point.
If your ejection fraction is below normal, it might indicate functional gallbladder disease even if other tests appear normal. However, your doctor will consider all your symptoms and test results together before making treatment recommendations.
Several factors can increase your chances of having an abnormal HIDA scan, though many people with these risk factors never develop gallbladder problems. Understanding these factors helps you and your doctor make informed decisions about your health.
Age and gender play significant roles in gallbladder disease. Women are more likely to develop gallbladder problems, especially during pregnancy or when taking hormone replacement therapy. The risk increases with age, particularly after 40.
These lifestyle and medical factors can increase your risk:
Some people develop gallbladder problems without any obvious risk factors. Genetics play a role, and certain ethnic groups, including Native Americans and Mexican Americans, have higher rates of gallbladder disease.
Pregnancy is a special consideration because hormonal changes can affect gallbladder function. If you're pregnant and need a HIDA scan, your doctor will carefully weigh the benefits against any potential risks.
While an abnormal HIDA scan itself doesn't cause complications, the underlying gallbladder problems it reveals can lead to serious health issues if left untreated. Understanding these potential complications helps you appreciate why follow-up care is so important.
Acute cholecystitis, shown by a gallbladder that doesn't fill with tracer, can progress to dangerous complications. The gallbladder wall can become severely inflamed, infected, or even rupture, requiring emergency surgery.
Here are the main complications that can develop from untreated gallbladder disease:
Functional gallbladder disease, where the gallbladder doesn't empty properly, can cause chronic pain and digestive problems. While not immediately life-threatening, it can significantly impact your quality of life and may eventually require surgery.
The good news is that most gallbladder problems can be treated effectively when caught early. Your doctor will work with you to develop a treatment plan that addresses your specific situation and prevents complications.
You should contact your doctor if you experience symptoms that might indicate gallbladder problems, especially if they're persistent or getting worse. Early evaluation can prevent complications and help you feel better sooner.
The most common gallbladder symptom is pain in your upper right abdomen, often called biliary colic. This pain typically starts suddenly, lasts 30 minutes to several hours, and may radiate to your back or right shoulder blade.
Here are symptoms that warrant medical attention:
Seek immediate medical care if you develop severe abdominal pain with fever, chills, or vomiting. These symptoms could indicate acute cholecystitis or other serious complications that require prompt treatment.
Don't ignore recurring mild symptoms either. Frequent indigestion, bloating, or discomfort after eating fatty foods might indicate functional gallbladder disease that could benefit from early intervention.
Q1:Q1: Is a HIDA scan safe during pregnancy?
HIDA scans are generally avoided during pregnancy unless absolutely necessary because they involve radioactive material. The amount of radiation is small, but doctors prefer to use safer alternatives like ultrasound when possible.
If you're pregnant and your doctor recommends a HIDA scan, it means the benefits likely outweigh the risks. They'll use the lowest possible dose of radioactive tracer and take special precautions to protect you and your baby.
Q2:Q2: Does a low ejection fraction always mean I need surgery?
Not necessarily. A low ejection fraction below 35-40% suggests your gallbladder isn't emptying properly, but surgery depends on your symptoms and overall health. Some people with low ejection fractions have no symptoms and don't need treatment.
Your doctor will consider your pain patterns, how symptoms affect your daily life, and other test results before recommending surgery. Many people with functional gallbladder disease do well with dietary changes and medications.
Q3:Q3: Can medications affect my HIDA scan results?
Yes, several medications can influence HIDA scan results. Narcotic pain medications can cause false positive results by preventing the gallbladder from filling properly. Some antibiotics and other drugs can also affect bile flow.
Always tell your doctor about all medications you're taking, including over-the-counter drugs and supplements. They might ask you to temporarily stop certain medications before the test to ensure accurate results.
Q4:Q4: How long does the radioactive tracer stay in my body?
The radioactive tracer used in HIDA scans has a short half-life and leaves your body naturally within 24-48 hours. Most of it is eliminated through your bile into your intestines and then in your bowel movements.
You don't need to take special precautions after the test, but drinking plenty of water can help flush the tracer out faster. The amount of radiation exposure is similar to what you'd get from a chest X-ray.
Q5:Q5: What happens if my gallbladder doesn't show up on the scan?
If your gallbladder doesn't fill with tracer during the scan, it usually indicates acute cholecystitis or severe gallbladder inflammation. This is considered a positive result for acute gallbladder disease.
Your doctor might give you morphine during the test to help concentrate the tracer and get a clearer picture. If your gallbladder still doesn't fill, you'll likely need prompt medical treatment, which often includes antibiotics and possibly surgery.