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What is TUIP? Purpose, Procedure & Results

Created at:1/13/2025

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TUIP stands for Transurethral Incision of the Prostate, a minimally invasive surgical procedure that helps men with enlarged prostate symptoms. Unlike more extensive prostate surgeries, TUIP involves making small, precise cuts in the prostate to relieve pressure on the urethra. This procedure is particularly effective for men with smaller prostates who experience bothersome urinary symptoms but want to avoid more invasive treatments.

What is TUIP?

TUIP is a surgical technique where your urologist makes one or two small incisions in your prostate gland to improve urine flow. Think of it like creating a small opening in a tight collar to make breathing easier. The procedure targets the area where your prostate wraps around your urethra, the tube that carries urine from your bladder.

During TUIP, your surgeon uses a thin, lighted instrument called a cystoscope that's inserted through your urethra. No external incisions are needed, which means you won't have any visible cuts on your body. The entire procedure typically takes 20 to 30 minutes and is performed under anesthesia.

This technique is specifically designed for men with prostates that are 30 grams or smaller in size. It's considered a middle ground between medication management and more extensive procedures like TURP (Transurethral Resection of the Prostate).

Why is TUIP done?

TUIP is recommended when your enlarged prostate causes bothersome urinary symptoms that haven't improved with medication. Your doctor might suggest this procedure if you're experiencing difficulty starting urination, weak urine stream, or frequent nighttime bathroom trips that affect your quality of life.

The main goal is to relieve the pressure your prostate puts on your urethra without removing prostate tissue. This approach preserves more of your natural anatomy compared to other prostate surgeries. You might be a good candidate if you have a smaller prostate but still experience significant symptoms.

Your urologist will also consider TUIP if you can't tolerate prostate medications due to side effects, or if medications haven't provided sufficient relief after several months of treatment. The procedure is particularly beneficial for younger men who want to maintain their sexual function and ejaculatory ability.

What is the procedure for TUIP?

Your TUIP procedure begins with anesthesia administration, either spinal or general, depending on your health status and preference. Once you're comfortable, your surgeon positions you on your back with your legs supported in stirrups, similar to other urological procedures.

The surgeon inserts a cystoscope through your urethra and guides it to your prostate area. This instrument has a light and camera that allows your doctor to see inside your urinary tract clearly. No external cuts are made anywhere on your body during this process.

Using an electrical cutting tool attached to the cystoscope, your surgeon makes one or two precise incisions in your prostate. These cuts are typically made at the 5 o'clock and 7 o'clock positions if you imagine your prostate as a clock face. The incisions extend from your bladder neck down to the area just before your external urinary sphincter.

After making the incisions, your surgeon may use electrical current to seal any bleeding vessels. A catheter is then inserted through your urethra into your bladder to help drain urine while your prostate heals. The entire procedure usually takes 20 to 30 minutes to complete.

How to prepare for your TUIP?

Your preparation starts about a week before surgery when you'll need to stop taking certain medications that can increase bleeding risk. These include blood thinners like warfarin, aspirin, and some herbal supplements. Your doctor will provide a specific list of medications to avoid and when to stop them safely.

You'll receive instructions about eating and drinking before surgery, typically requiring you to fast for 8 to 12 hours beforehand. This precaution helps prevent complications during anesthesia. Your medical team will give you specific times for when to stop eating solid foods and when to stop drinking clear liquids.

Arrange for someone to drive you home after the procedure since you'll still be recovering from anesthesia. You'll also want to prepare your home for recovery by having comfortable seating, easy-to-prepare meals, and any prescribed medications readily available.

Your doctor might recommend stopping certain supplements like vitamin E, ginkgo biloba, or garlic pills that can affect blood clotting. If you take medications for other conditions, ask your doctor which ones you should continue taking on the morning of surgery.

How to read your TUIP results?

Your TUIP results are primarily measured by improvement in your urinary symptoms rather than laboratory numbers. Success is typically evaluated through symptom questionnaires like the International Prostate Symptom Score (IPSS) that you'll complete before and after surgery.

Your doctor will assess improvement in several key areas: how easily you start urinating, the strength of your urine stream, how completely you empty your bladder, and how often you need to urinate during the day and night. Most men notice improvements within 2 to 6 weeks after surgery.

Objective measurements include urine flow rate tests, where you urinate into a special device that measures how fast urine flows out of your bladder. A normal flow rate is typically 15 milliliters per second or higher. Your doctor might also use ultrasound to check how much urine remains in your bladder after urination.

Long-term success rates for TUIP show that about 80% of men experience significant symptom improvement that lasts for several years. However, some men may need additional treatment if their prostate continues to grow over time.

How to manage your recovery after TUIP?

Your immediate recovery begins in the hospital where you'll stay for 1 to 2 days with a urinary catheter in place. The catheter helps drain your bladder while your prostate heals and reduces the risk of urinary retention. You might notice some blood in your urine initially, which is completely normal.

Once you're home, you'll need to drink plenty of water to help flush your urinary system and prevent infection. Aim for 8 to 10 glasses of water daily unless your doctor advises otherwise. Avoid alcohol and caffeine initially, as these can irritate your healing tissues.

Physical activity should be limited for the first few weeks after surgery. Avoid heavy lifting (more than 10 pounds), vigorous exercise, and straining during bowel movements. These activities can increase pressure in your abdomen and potentially cause bleeding.

You can expect to return to normal activities gradually over 2 to 4 weeks. Most men can return to desk work within a few days, while those with physically demanding jobs might need 2 to 3 weeks off. Your doctor will provide specific guidelines based on your healing progress.

What are the risk factors for TUIP complications?

Certain health conditions can increase your risk of complications during or after TUIP. Men with uncontrolled diabetes face higher risks of infection and slower healing. If you have diabetes, your doctor will want your blood sugar levels well-controlled before surgery.

Heart conditions and blood clotting disorders require special attention during TUIP planning. If you take blood thinners for heart problems or have a history of bleeding disorders, your surgical team will need to carefully manage these factors. Your cardiologist and urologist will work together to ensure your safety.

Age alone isn't a barrier to TUIP, but older men may have multiple health conditions that need consideration. Men over 75 might have longer recovery times and slightly higher risks of complications like urinary retention or infection.

Prostate size matters significantly for TUIP success. Men with very large prostates (over 30 grams) typically aren't good candidates because the procedure may not provide adequate relief. Your doctor will measure your prostate size using ultrasound or MRI before recommending TUIP.

What are the possible complications of TUIP?

Common complications after TUIP are generally mild and temporary. You might experience some burning sensation during urination for a few days, which usually resolves as your tissues heal. Some men notice small amounts of blood in their urine for up to two weeks after surgery.

Urinary tract infections occur in about 5% to 10% of men after TUIP. Symptoms include burning during urination, frequent urination, cloudy urine, or fever. These infections typically respond well to antibiotic treatment and don't usually cause long-term problems.

Sexual function changes are less common with TUIP compared to other prostate procedures. Most men maintain their ability to have erections and orgasms. However, some men might experience retrograde ejaculation, where semen flows backward into the bladder instead of out through the penis during orgasm.

Rare but serious complications include significant bleeding requiring blood transfusion, which occurs in less than 1% of cases. Some men might experience temporary inability to urinate after catheter removal, requiring catheter reinsertion for a few more days. Very rarely, the incisions might not heal properly, requiring additional treatment.

When should I see a doctor after TUIP?

Contact your doctor immediately if you experience heavy bleeding with large clots, severe pain not relieved by prescribed medications, or signs of infection like fever over 101°F (38.3°C). These symptoms could indicate complications that need prompt medical attention.

You should also call your doctor if you're unable to urinate after your catheter is removed, or if you have persistent nausea and vomiting that prevents you from staying hydrated. These situations might require temporary catheter placement or other interventions.

Schedule a follow-up appointment if you notice your urinary symptoms haven't improved after 6 to 8 weeks of healing. While some men see immediate improvement, others need more time to experience the full benefits of the procedure.

Watch for signs of urinary tract infection, including burning during urination, cloudy or foul-smelling urine, or increased urinary frequency. Early treatment of infections helps prevent more serious complications and promotes better healing.

Frequently asked questions about Transurethral incision of the prostate (TUIP)

TUIP and medication serve different purposes in treating enlarged prostate symptoms. Medications like alpha-blockers and 5-alpha reductase inhibitors work well for many men and are typically tried first. However, TUIP becomes a better option when medications don't provide adequate relief, cause unacceptable side effects, or when you prefer a more definitive treatment.

The advantage of TUIP is that it provides longer-lasting relief without the need for daily medication. Most men experience significant improvement that lasts several years. However, medications are less invasive and don't carry surgical risks, making them appropriate for men with mild symptoms or those who aren't good surgical candidates.

TUIP typically has minimal impact on sexual function compared to other prostate procedures. Most men maintain their ability to have erections and experience orgasms after TUIP. The procedure is specifically designed to preserve the nerves and structures important for sexual function.

Some men might experience retrograde ejaculation, where semen flows backward into the bladder during orgasm instead of out through the penis. This doesn't affect the sensation of orgasm or your ability to have erections, but it can impact fertility since less semen is ejaculated.

TUIP provides long-lasting symptom relief for most men, with studies showing good results lasting 5 to 10 years or more. About 80% of men experience significant improvement that maintains over time. However, since the prostate can continue growing throughout a man's life, some symptoms might gradually return.

The duration of relief depends partly on your age, overall health, and how much your prostate grows over time. Younger men might experience longer-lasting benefits, while older men might need additional treatment sooner due to continued prostate growth.

Yes, TUIP can be repeated if your symptoms return and you're still a good candidate for the procedure. However, repeat TUIP procedures are less common than with other prostate treatments. If symptoms return significantly, your doctor might recommend alternative treatments like TURP or newer procedures.

The decision to repeat TUIP depends on your prostate size, overall health, and the degree of symptom return. Your urologist will evaluate these factors and discuss the best options for your specific situation.

Most health insurance plans, including Medicare, cover TUIP when it's medically necessary for treating enlarged prostate symptoms. However, coverage requirements vary between insurance companies and plans. Your doctor's office typically handles insurance pre-authorization to ensure the procedure is covered.

You'll want to check with your insurance provider about your specific coverage details, including any deductibles, co-pays, or out-of-pocket costs. Some insurance plans might require you to try medication treatment first before approving surgical procedures like TUIP.

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