He SSRI ka Effexor? Kēia Antidepressant Maʻa Mau

E hele pololei kākou i ke kumuhana: ʻAʻole, ʻaʻole he SSRI ka Effexor. No kahi ʻē aʻe akā pili pono ia ia ʻano antidepressants i kapa ʻia ʻo SNRIs.

Inā ua kau ʻia ʻoe me Effexor (a i ʻole kona ʻano generic, venlafaxine), e hoʻāʻo paha ʻoe e hoʻomaopopo i ka ʻōlelo lapaʻau. Ua lohe paha ʻoe i nā antidepressants maʻa mau e like me Zoloft lāua ʻo Prozac, ʻo ia hoʻi nā SSRIs, a maʻalahi ka manaʻo inā ʻo Effexor ka ʻohana like.

ʻOiai ʻo nā SSRIs a me nā SNRIs he mau mea hana ikaika no ka mālama ʻana i ke kaumaha a me ka hopohopo, hana lākou i ka chemistry o kou lolo i nā ʻano liʻiliʻi. ʻO ka hoʻomaopopo ʻana i kēia ʻokoʻa ke kī i ka hoʻomaopopo ʻana i kāu lapaʻau.

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He aha ka Effexor (Venlafaxine)? Ka Hoʻomaopopo ʻana i ka Papa SNRI

No laila, inā ʻaʻole ia he SSRI, ʻo ia pūʻulu lāʻau hea ka Effexor? ʻO Effexor, me ka inoa generic venlafaxine, he Serotonin-Norepinephrine Reuptake Inhibitor, a i ʻole SNRI no ka pōkole.

He waha nui kēnā, no laila e wehe kāua.

Hoʻohana kou lolo i nā ʻelele kemika i kapa ʻia ʻo neurotransmitters e kamaʻilio ma waena o nā ʻiʻo naʻau. ʻElua o nā neurotransmitters koʻikoʻi no ka hoʻoponopono ʻana i ke ʻano, ke koʻikoʻi, a me ka nānā ʻana ʻo:

• Serotonin: I kapa ʻia hoʻi ʻo ka kemika “ʻoluʻolu”, he kuleana nui ia i kou ʻano, hiamoe, ʻai, a me nā manaʻo olakino.
• Norepinephrine: Loaʻa kēia kemika i ka pane “kaua a lele” o kou kino. Hoʻopili ia i kou pae ikehu, ka makaʻala, a me ka hiki ke noʻonoʻo.

Ma hope o ka lawe ʻana o kēia mau ʻelele i kā lākou hōʻailona, ​​​​hoʻihoʻi ʻia lākou e nā ʻiʻo naʻau i kahi kaʻina i kapa ʻia ʻo “reuptake.” ʻO ka hana a Effexor ka pale ʻana i kēia kaʻina hana hou no ka ʻelua serotonin a me norepinephrine. Ma ka hana ʻana pēlā, hoʻonui ia i nā pae hana o kēia mau neurotransmitters koʻikoʻi ʻelua i loko o kou lolo, hiki ke kōkua i ka hoʻomaha ʻana i nā hōʻailona o ke kaumaha a me ka hopohopo source. ʻO kēia hana pālua ka hiʻohiʻona hoʻokaʻawale o ka venlafaxine mechanism of action.

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He aha ka SSRI? Ka Hana Hoʻokahi

No ka hoʻomaopopo ʻana i ke kumu nui ai ka lepili “SNRI”, pono ke nānā aku i kona hoahānau kaulana, ka SSRI.

ʻO SSRI ke ʻano o Selective Serotonin Reuptake Inhibitor. E like me ka manaʻo o ka inoa, hana kēia mau lāʻau lapaʻau i ka koho ma ka serotonin. Hana lākou i ka hana like “reuptake blocking” e like me Effexor, akā hoʻopaʻa lākou i hoʻokahi neurotransmitter: serotonin source.

Ma ka hoʻonui ʻana i nā pae serotonin, hiki i nā SSRIs ke hoʻomaikaʻi maikaʻi i ke ʻano a hoʻemi i nā manaʻo hopohopo. Loaʻa i kēia papa ʻo kekahi o nā antidepressants i kau ʻia ma ka honua holoʻokoʻa, e like me:

• Zoloft (sertraline)
• Lexapro (escitalopram)
• Prozac (fluoxetine)
• Celexa (citalopram)

ʻO ka poʻe he nui e nīnau ana “He SSRI ka Effexor?” ua kamaʻāina i kēia mau inoa, e hoʻomanaʻo ana i ka ʻokoʻa.

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Ka ʻOkoʻa Kūʻokoʻa: Pehea ka Hana ʻo Effexor (SNRI) vs. SSRIs

I kēia manawa e hele kāua i ke kumu. ʻO ka ʻokoʻa kumu ma waena o ka SNRI vs SSRI hele mai i hoʻokahi kūʻokoʻa ʻelua neurotransmitters.

• SSRIs (Ka Loaʻa): E noʻonoʻo i kahi SSRI e like me he mea loea e nānā ana i hoʻokahi mea a hana maikaʻi ia. Hoʻopaʻa ia i ka serotonin e kōkua i ka hoʻoponopono ʻana i ke ʻano, hiamoe, a me ka hopohopo. No ka poʻe he nui, ʻo kēia ka hoʻoulu ʻana i makemake ai ko lākou lolo chemistry.

• Effexor (Ka Hana Pālua): Hana ʻo Effexor, ma ke ʻano he SNRI, ma ka serotonin a me norepinephrine. ʻO ia hoʻi, hāʻawi ia i nā pono hoʻopaʻa ʻano o ka hoʻonui ʻana i ka serotonin, a me ka hiki ke hoʻomaikaʻi i ka ikehu, ka makaʻala, a me ka nānā ʻana mai ka hoʻonui ʻana i ka norepinephrine.

Hoʻololi ka Dosi i ka ʻokoʻa

ʻO kekahi o nā mea kū hoʻokahi loa e pili ana i ka venlafaxine mechanism of action ʻo kāna mau hopena e pili ana i ka dōsi. ʻO ia hoʻi, hiki ke hoʻololi i kāna hana i ka wā e hoʻoponopono ai kāu kauka i kāu dōsi:

• Ma nā dōsi haʻahaʻa (ma lalo o 150 mg/lā): Hana ʻo Effexor ma ke ʻano he SSRI, hoʻopaʻa ʻia ma ka serotonin reuptake.
• Ma nā dōsi kiʻekiʻe (ma luna o 150 mg/lā): Hoʻomaka kāna mau hana pale norepinephrine a lilo i mea koʻikoʻi. Ma kēia mau pae, loaʻa iā ʻoe ka pono piha o ka hana pālua o kahi SNRI source.

ʻO kēia pilina dōsi-pane ke kumu nui i koho ai kāu kauka iā Effexor. Hāʻawi ia iā lākou e hoʻomaka ma ka hoʻopaʻa ʻana i ka serotonin a laila hoʻolauna i ka ʻāpana norepinephrine inā pono, me hoʻokahi lāʻau lapaʻau. ʻO kēia ʻokoʻa ke kumu o ka hoʻopaʻapaʻa Effexor vs SSRI ke hoʻoholo nei ka mea lapaʻau i ka lapaʻau kūpono.

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Ka Hoʻohālikelike ʻana i nā Maʻi i Mālama ʻia, nā Hopena ʻē aʻe, a me ka Hoʻōla

No ka mea ʻokoʻa ko lākou hana, hiki i nā SNRIs a me nā SSRIs ke loaʻa nā ʻokoʻa i ka wā e pili ana i kā lākou mea e mālama ai, ko lākou mau hopena ʻē aʻe, a me ka mea e hana ai ke hoʻōki ʻoe i ka lawe ʻana iā lākou. Inā ʻoe e nīnau ana “He SSRI a i ʻole SNRI ka venlafaxine,” ʻo kēia ka ʻike i ka mea nui.

Nā Maʻi i Mālama ʻia

ʻO nā ʻano lāʻau ʻelua he mau mea hana maʻa mau i ka lapaʻau olakino noʻonoʻo, akā aia kekahi mau ʻokoʻa.

• Ua ʻae ʻia ʻo Effexor (Venlafaxine) e ka FDA e mālama i:

  • Major Depressive Disorder (MDD)
  • Generalized Anxiety Disorder (GAD)
  • Social Anxiety Disorder (SAD)
  • Panic Disorder
  • Hoʻohana ʻia hoʻi ia no nā maʻi e like me PTSD a me kekahi ʻano o ka ʻeha mau, e like me ka fibromyalgia, kahi e pāʻani ai ka norepinephrine.

• Hoʻohana ʻia nā SSRIs e like me Zoloft a me Lexapro no:

  • MDD, GAD, SAD, a me Panic Disorder (e like me Effexor)
  • Obsessive-Compulsive Disorder (OCD)
  • Post-Traumatic Stress Disorder (PTSD)

Ke hoʻohālikelike ʻana i ka Effexor vs Zoloft a i ʻole Effexor vs Lexapro, ʻo kāu maʻi maʻi kūpono ka mea nui e koho ai kāu kauka. No ka laʻana, inā loaʻa i ka mea maʻi ke kaumaha a me ka ʻeha mauʻiʻo, hiki ke noʻonoʻo ʻia kahi SNRI e like me Effexor he koho maikaʻi.

Nā Hopena ʻē aʻe Maʻa Mau

He nui nā hopena ʻē aʻe o Effexor e like me nā SSRIs no ka mea ʻo nā ʻano lāʻau ʻelua e hoʻopili i ka serotonin. Hiki i kēia mau hopena ʻē aʻe i kaʻana like ke komo source:

• ʻO ka nausea (ʻoi aku ka nui i ka wā mua)
• Ka hiamoe a luhi paha
• Ka huikau
• Ka waha maloʻo
• Nā hopena ʻē aʻe o ka wahine (ka emi o ka makemake, ka pilikia me ka orgasm)
• Ka insomnia

Eia naʻe, ma muli o kāna hopena i ka norepinephrine, he nui nā hopena ʻē aʻe ʻo Effexor ʻaʻole pinepine me nā SSRIs:

• Ka piʻi ʻana o ke koko: Hiki i ka Norepinephrine ke hoʻopaʻa i nā kīʻaha koko, no laila ua ʻōlelo pinepine ʻia ka nānā ʻana i ke koko.
• Ka piʻi ʻana o ka puʻuwai
• Ka hou ʻana
• Ka huhū a hopohopo paha (ʻoi aku ka nui i ka hoʻomaka ʻana o ka lapaʻau)

Ka Paʻa o ka Syndrome Withdrawal

ʻO kēia kekahi o nā ʻokoʻa koʻikoʻi loa. ʻOiai hiki i ka hoʻōki ʻana i kekahi antidepressant ke hoʻokumu i nā hōʻailona hoʻopau, ʻo ka withdrawal o Effexor ua ʻike ʻia he mea maʻa mau a paʻakikī.

ʻO kēia ma muli o ka pōkole loa o ka "half-life" o Effexor—ʻo ia hoʻi, hoʻoponopono ʻia a hoʻomaʻemaʻe ʻia mai kou kino ma kahi wikiwiki. Inā hala ʻoe i kahi dōsi a i ʻole hoʻōki koke iā ia, hiki i nā pae neurotransmitter o kou lolo ke emi koke, e alakaʻi ana i kahi pūʻulu o nā hōʻailona ʻoluʻolu ʻole i kapa ʻia ʻo “discontinuation syndrome” source.

ʻO nā hōʻailona maʻa mau o ka withdrawal o Effexor e komo pū ana:

• “Brain zaps” (he manaʻo e like me ka uila uila i loko o ke poʻo)
• Ka huikau nui a me ka vertigo
• ʻO ka nausea a me ka luaʻi
• Ka luhi
• Ka huhū a hopohopo
• Nā hōʻailona flu

Ma muli o kēia, he mea nui loa ʻaʻole e hoʻōki koke i ka lawe ʻana iā Effexor. E kōkua kāu kauka iā ʻoe e hana i kahi hoʻolālā tapering lohi loa e hoʻomaha ai i kēia mau hopena withdrawal. No laila, ʻoiai ʻoe e noʻonoʻo ana He SSRI a i ʻole SNRI ka venlafaxine, ʻo ka hoʻomaopopo ʻana i kāna ʻano withdrawal kūʻokoʻa ka ʻāpana koʻikoʻi o ka pane.

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Ka ʻIke Palekana Koʻikoʻi e ʻIke

E like me kekahi lāʻau lapaʻau, he mau ʻōlelo aʻo palekana koʻikoʻi ʻo Effexor āu a me kāu kauka e pono ke kūkākūkā.

• Serotonin Syndrome: He maʻi kakaʻikahi akā hiki ke make ka maʻi i hoʻokumu ʻia e ka nui o ka serotonin i loko o kou ʻōnaehana. Hoʻonui ka pilikia inā lawe ʻoe iā Effexor me nā lāʻau ʻē aʻe e hoʻonui ai i ka serotonin, e like me nā antidepressants ʻē aʻe (ʻoi aku nā MAOIs), nā triptans no ka migraines, a i ʻole kekahi mau lāʻau hoʻomaha ʻeha. Hiki i nā hōʻailona ke komo i ka huhū, ka huikau, ka wikiwiki o ka puʻuwai, ke koko kiʻekiʻe, a me ka ʻiʻo ʻiʻo source. E ʻimi koke i ka lāʻau lapaʻau inā ʻike ʻoe i kēia mau hōʻailona.

• FDA Black Box Warning: Pono ka U.S. Food and Drug Administration (FDA) i nā antidepressants āpau, me Effexor, e lawe i kahi hōʻailona pahu—ʻo kāna ʻano koʻikoʻi loa. ʻŌlelo kēia hōʻailona e hiki i nā antidepressants ke hoʻonui i ka pilikia o nā manaʻo a me nā hana pepehi kanaka i nā keiki, ʻōpio, a me nā ʻōpio ʻōpio (a hiki i ka makahiki 25). He mea nui e nānā i kekahi hōʻino ʻana o ke ʻano a i ʻole ka puka ʻana mai o ka manaʻo pepehi kanaka, ʻoi aku ka nui i ka wā mua o ka lawe ʻana i ka lāʻau a i ʻole ke hoʻololi ʻana i ka dōsi source.

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Ka Manaʻo: He SNRI ka Effexor, a He Manaʻo Koʻikoʻi ia

No laila, e hoʻi kāua i kā mākou nīnau mua: He SSRI ka Effexor?

ʻO ka pane paʻa ʻo ʻole. He Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) ʻo Effexor, e hoʻokaʻawale iā ia mai nā SSRIs e like me Zoloft a me Lexapro no ka mea hana ia ma nā neurotransmitters koʻikoʻi ʻelua ma mua o hoʻokahi.

ʻO kēia hana pālua Effexor vs SSRI ka mea e hāʻawi ai i kona ʻano kūʻokoʻa—mai kāna mau hopena dōsi-dependent a me ka hiki ke kōkua i ka ikehu a me ka nānā ʻana, i kāna mau hopena ʻē aʻe kūikawā a me kahi syndrome withdrawal paʻakikī loa. ʻO ka hoʻomaopopo ʻana i ka ʻano lāʻau a Effexor ka mea mua e lilo ai ʻoe i mea komo ʻike a ikaika i kāu huakaʻi olakino noʻonoʻo.

Ma ka hopena, ʻo ka mea kūpono ka SNRI a i ʻole ka SSRI no ʻoe he hoʻoholo paʻakikī ia e pili ana i kou mau hōʻailona kūikawā, ka mōʻaukala lapaʻau, a me ka chemistry o kou lolo. He kūkākūkā kēia me kāu mea mālama ola. Mai hoʻomaka, hoʻōki, a hoʻololi paha i kāu dōsi lāʻau me ka ʻole o kā lākou alakaʻi. ʻO lākou kāu hoaaloha maikaʻi loa i ka ʻimi ʻana i ke ala e alakaʻi ai i kou olakino.