ʻapena O Addison

ʻO ka maʻi Addison he kūlana maʻamau ʻole ia e hiki mai ana i ka wā ʻaʻole lawa ka hana ʻana o ke kino i kekahi mau hormones. ʻO kekahi inoa no ka maʻi Addison, ʻo ia ka nele nui o ka adrenal mua. Me ka maʻi Addison, hana nā gland adrenal i ka liʻiliʻi o ka hormone cortisol. I ka manawa pinepine, hana lākou i ka liʻiliʻi o kekahi hormone i kapa ʻia ʻo aldosterone. ʻO ka pōʻino i nā gland adrenal ka mea e hoʻokumu ai i ka maʻi Addison. Hiki ke hoʻomaka mālie nā hōʻailona. ʻO nā hōʻailona mua e komo pū ai ka luhi nui, ka makemake i ka paʻakai a me ka pohō kaumaha. Hiki i ka maʻi Addison ke hoʻopili i kekahi. Me ka ʻole o ka mālama ʻana, hiki ke hoʻoweliweli i ke ola. ʻO ka mālama ʻana e komo pū ana me ka lawe ʻana i nā hormones i hana ʻia e ka labo e pani i nā mea i nele.

ʻO nā hōʻailona o ka maʻi Addison e hana mau ana me ka lohi, pinepine ma luna o nā mahina. Hiki paha i ka maʻi ke hana me ka lohi loa i hiki i nā kānaka i loaʻa iā ia ke hoʻowahāwahā i nā hōʻailona i ka hoʻomaka. Hiki i ka pilikia kino e like me ka maʻi a i ʻole ka hōʻeha ke hana i nā hōʻailona e ʻoi aku ka nui. Hiki i nā hōʻailona mua o ka maʻi Addison ke hoʻopili iā ʻoe ma nā ʻano like ʻole. Hiki i kekahi mau hōʻailona mua ke hoʻokumu i ka ʻoluʻolu ʻole a i ʻole ka nalowale o ka ikehu, e komo pū ana: Ka luhi nui, i kapa ʻia hoʻi he luhi. Ke pohihihi a i ʻole ka hiolo ʻana i ka wā e kū ana ma hope o ka noho ʻana a i ʻole ka moe ʻana. ʻO kēia ma muli o ke ʻano o ke koko haʻahaʻa i kapa ʻia ʻo postural hypotension. Ke hoʻoheheʻe ʻana ma muli o ke kōpaʻa haʻahaʻa, i kapa ʻia hoʻi he hypoglycemia. Ka ʻōpū ʻino, ka luaʻi a i ʻole ka luaʻi. ʻEha i ka wahi o ka ʻōpū, i kapa ʻia hoʻi he ʻōpū. Nā ʻeha o nā mākala, nāwaliwali, ka ʻeha ākea a i ʻole ka ʻeha o nā hono. Hiki i nā hōʻailona mua ʻē aʻe ke hoʻololi i ke ʻano o kou helehelena, e like me: Ka nalowale o ka lauoho kino. Nā wahi o ka ʻili ʻeleʻele, ʻoi aku hoʻi ma nā ʻeha a me nā moles. Hiki paha i kēia mau loli ke paʻakikī ke ʻike ma ka ʻili ʻeleʻele a ʻulaʻula paha. Ka nalowale o ke kaupaona ma muli o ka liʻiliʻi o ka pōloli. Hiki i nā hōʻailona mua o ka maʻi Addison ke hoʻopili i nā manaʻo, ka olakino noʻonoʻo a me nā makemake. ʻO kēia mau hōʻailona e komo pū ana: Kaumaha. ʻAno huhū. Ka emi ʻana o ka makemake moekolohe i nā wahine. Ke makemake i ka paʻakai. I kekahi manawa, e ʻoi aku ka nui o nā hōʻailona o ka maʻi Addison. Inā hana kēia, he pilikia ia i ʻike ʻia he pilikia adrenal. Hiki iā ʻoe ke lohe iā ia i kapa ʻia he pilikia addisonian a i ʻole ka hāʻule adrenal ʻoi aku. Kāhea i ka 911 a i ʻole kāu helu pilikia kūloko inā loaʻa iā ʻoe ka maʻi Addison me kekahi o nā hōʻailona penei: Nāwaliwali nui. ʻEha koke, weliweli i ka hope haʻahaʻa, ka wahi o ka ʻōpū a i ʻole nā ​​wāwae. Ka ʻōpū ʻino nui, ka luaʻi a i ʻole ka luaʻi. Ka nalowale nui o ka wai kino, i kapa ʻia hoʻi he dehydration. Ke kuni. Ka huikau a i ʻole ka emi nui o ka ʻike o nā mea a puni. Ka nalowale o ka ʻike. Ke koko haʻahaʻa a me ka hiolo ʻana. Me ka ʻole o ka mālama wikiwiki, hiki i ka pilikia adrenal ke alakaʻi i ka make. E ʻike i kahi loea olakino inā loaʻa iā ʻoe nā hōʻailona maʻamau o ka maʻi Addison, e like me: Ka luhi lōʻihi. Ka nāwaliwali o nā mākala. Ka nalowale o ka makemake. Nā wahi ʻeleʻele o ka ʻili. Ka nalowale o ke kaupaona ʻaʻole i hana ʻia ma ke kumu. Ka ʻōpū ʻino nui, ka luaʻi a i ʻole ka ʻeha o ka ʻōpū. Ke pohihihi a i ʻole ka hiolo ʻana me ke kū ʻana. Ke makemake i ka paʻakai. E kiʻi i ka mālama pilikia koke inā loaʻa iā ʻoe kekahi hōʻailona o ka pilikia adrenal.

E ʻimi i kahi kauka lapaʻau inā loaʻa iā ʻoe nā hōʻailona maʻamau o ka maʻi Addison, e like me: Luhi lōʻihi. Nawaliwali o nā ʻiʻo. Nalo o ka makemakeʻai. ʻEleʻele nā wahi o ka ʻili. Pau ke kaumaha me ka manaʻo ʻole. ʻO ka ʻōpū ʻino nui, ka luaʻi a i ʻole ka ʻeha o ka ʻōpū. Mālamalama a i ʻole ka hiolo ʻana i ka kū ʻana. Makemake i ka paʻakai. E kiʻi koke i ka mālama pilikia inā loaʻa iā ʻoe kekahi hōʻailona o ka pilikia adrenal.

Hōʻino ʻia nā kīʻaha adrenal e hoʻokumu ai i ka maʻi Addison. Aia kēia mau kīʻaha ma luna pono o nā puʻupaʻa. ʻO nā kīʻaha adrenal he ʻāpana ia o ka ʻōnaehana o nā kīʻaha a me nā kino e hana ana i nā hormones, i kapa ʻia hoʻi ʻo ka ʻōnaehana endocrine. Hana nā kīʻaha adrenal i nā hormones e hoʻopili kokoke ana i kēlā me kēia kino a me ka ʻiʻo o ke kino. Hana ʻia nā kīʻaha adrenal i ʻelua papa. ʻO ka papa o loko, i kapa ʻia ʻo ka medulla, hana i nā hormones e like me ka adrenaline. Hoʻokele kēlā mau hormones i ka pane o ke kino i ke kaumaha. ʻO ka papa o waho, i kapa ʻia ʻo ka cortex, hana i kahi hui o nā hormones i kapa ʻia ʻo corticosteroids. Loaʻa i nā Corticosteroids: Glucocorticoids. Loaʻa kēia mau hormones i ka cortisol, a hoʻopili lākou i ka hiki o ke kino ke hoʻohuli i ka meaʻai i ikehu. Loaʻa pū lākou i kahi kuleana i ka ʻōnaehana pale a kōkua i ke kino e pane i ke kaumaha. Mineralocorticoids. Loaʻa kēia mau hormones i ka aldosterone. Hoʻoponopono lākou i ka sodium a me ka potassium o ke kino e mālama i ke kaomi koko i kahi pae olakino. Androgens. I nā kānaka a pau, hana nā kīʻaha adrenal i kahi liʻiliʻi o kēia mau hormones moekolohe. Hoʻokumu lākou i ka hoʻomohala moekolohe kāne. A hoʻopili lākou i ka nui o nā ʻiʻo, ka lauoho o ke kino, ka manaʻo moekolohe, a me ka manaʻo maikaʻi i nā kānaka a pau. Ua ʻike ʻia hoʻi ka maʻi Addison ma ke ʻano he nele adrenal mua. ʻO kahi kūlana pili i kapa ʻia ʻo ka nele adrenal lua. Loaʻa i kēia mau kūlana nā kumu like ʻole. Hana kēia kūlana ke hōʻino ʻia ka papa o waho o nā kīʻaha adrenal a ʻaʻole hiki ke hana i nā hormones lawa. ʻO ka hapa nui, ʻo ka hōʻino ʻana mai kahi maʻi kahi e hoʻouka ai ka ʻōnaehana pale i nā pūnaewele a me nā kino olakino ma ka hewa. Kēia ka mea i kapa ʻia ʻo ka maʻi autoimmune. ʻOi aku ka nui o nā kānaka me ka maʻi Addison ma mua o nā kānaka ʻē aʻe e loaʻa pū kekahi maʻi autoimmune. ʻO nā kumu ʻē aʻe o ka maʻi Addison hiki ke komo pū: Kahi maʻi koʻikoʻi i kapa ʻia ʻo ka maʻi palū e hoʻopili nui ana i nā māmā a hiki ke hoʻopau i nā kīʻaha adrenal. Nā maʻi ʻē aʻe o nā kīʻaha adrenal. Hoʻolaha ʻia ka maʻi kanesa i nā kīʻaha adrenal. Ke koko i loko o nā kīʻaha adrenal. Kahi hui o nā kūlana genetic i loaʻa i ka hānau ʻana e hoʻopili ana i nā kīʻaha adrenal. Kēia ka mea i kapa ʻia ʻo ka hyperplasia adrenal congenital. Nā lāʻau lapaʻau e pale ana i ka hiki o ke kino ke hana i ka glucocorticoid, e like me ke ketoconazole (Ketozole), mitotane (Lysodren) a me etomidate (Amidate). A i ʻole nā ​​​​lāʻau lapaʻau e pale ana i ka hana o ka glucocorticoid i ke kino, e like me ka mifepristone (Mifeprex, Korlym). Lapaʻau no ka maʻi kanesa me nā lāʻau lapaʻau i kapa ʻia ʻo nā mea pale checkpoint. Loaʻa i kēia ʻano o ka nele adrenal nā hōʻailona he nui i like me ka maʻi Addison. Akā ʻoi aku ka nui ma mua o ka maʻi Addison. Hana ka nele adrenal lua ke ʻaʻole hoʻoikaika ka pituitary gland kokoke i ka lolo i nā kīʻaha adrenal e hana i ka cortisol. Ma ke ʻano maʻamau, hana ka pituitary gland i kahi hormone i kapa ʻia ʻo adrenocorticotropic hormone (ACTH). Hoʻokumu ka ACTH i ka papa o waho o nā kīʻaha adrenal e hana i kāna mau hormones, me nā glucocorticoids a me nā androgens. Akā me ka nele adrenal lua, ʻo ka liʻiliʻi o ka ACTH e hoʻokumu ai i nā kīʻaha adrenal e hana i ka liʻiliʻi o kēia mau hormones. ʻO ka hapa nui o nā hōʻailona o ka nele adrenal lua e like me nā mea o ka maʻi Addison. Akā ʻaʻole loaʻa i nā kānaka me ka nele adrenal lua ka ʻili ʻeleʻele. A ʻoi aku ka liʻiliʻi o ka loaʻa ʻana o ka maloʻo nui a i ʻole ke kaomi koko haʻahaʻa. ʻOi aku ka nui o ka loaʻa ʻana o ka haʻahaʻa o ke kō koko. ʻO nā mea e hiki ke hoʻokumu i ka pituitary gland e hana i ka liʻiliʻi o ka ACTH e komo pū: Nā tumors pituitary ʻaʻole kanesa. ʻO ka ʻoki a i ʻole ka radiation therapy o ka pituitary gland. Hōʻino ʻia ka lolo. Hiki i kahi kumu pōkole o ka nele adrenal lua ke hana i nā kānaka e hoʻōki koke i ka lawe ʻana i nā lāʻau lapaʻau i kapa ʻia ʻo corticosteroids. Hoʻoponopono kēia mau lāʻau lapaʻau i nā kūlana e like me ka maʻi hanu a me ka maʻi ʻili. Akā ʻo ka hoʻōki koke ʻana i ka lāʻau lapaʻau ma mua o ka hoʻemi ʻana e hiki ke alakaʻi i ka nele adrenal lua.

ʻO ka hapa nui o ka poʻe i loaʻa i ka maʻi Addison ʻaʻohe o lākou mau kumu e hoʻonui ai i ka pilikia o ka loaʻa ʻana o ia maʻi. Akā, ʻo kēia mau mea ma lalo nei paha e hoʻonui i ka pilikia o ka nele o ka adrenal: Ka mōʻaukala o ka loaʻa ʻana o kahi maʻi a i ʻole ka hana ʻoki e pili ana i ka pituitary gland a i ʻole nā ​​glands adrenal. Nā loli genetical e pili ana i ka pituitary a i ʻole nā ​​glands adrenal. Loaʻa kēia i nā loli gene e hoʻokumu ai i ka maʻi hoʻoilina congenital adrenal hyperplasia. Nā kūlana endocrine autoimmune ʻē aʻe, e like me ka hypothyroidism a i ʻole ka maʻi diabetes type 1. Ka hōʻeha traumatic i ka lolo.

Hiki i ka maʻi Addison ke alakaʻi i nā kūlana olakino ʻē aʻe i kapa ʻia he mau pilikia. ʻO kēia mau mea e komo pū ana ka pilikia adrenal, i kapa ʻia hoʻi ʻo ka pilikia addisonian. Inā loaʻa iā ʻoe ka maʻi Addison a ʻaʻole i hoʻomaka ʻia ka mālama ʻana, hiki iā ʻoe ke loaʻa kēia pilikia weliweli i ke ola. Hiki i ke kaumaha ma ke kino e like me ka hōʻeha, ka maʻi a i ʻole ka maʻi ke hoʻoulu i ka pilikia adrenal. Ma ke ʻano maʻamau, hana nā gland adrenal i ʻelua a ʻekolu paha manawa o ka nui maʻamau o ka cortisol ma ke pane ʻana i ke kaumaha kino. Akā me ka nele adrenal, ʻaʻole lawa ka cortisol i hana ʻia e nā gland adrenal e hoʻokō i kēia pono. A hiki i kēlā ke alakaʻi i ka pilikia adrenal. Hoʻopuka ka pilikia adrenal i ka haʻahaʻa o ke koko, ka haʻahaʻa o ke kō i loko o ke koko a me ke kiʻekiʻe o ke potassium i loko o ke koko. Pono koke kēia pilikia i ka mālama ʻana.