Alpha Gal Syndrome

ʻO ka Alpha-gal syndrome kahi ʻano o ka maʻi ʻai. Hana ia i nā kānaka e maʻi ʻona i ka ʻiʻo ʻulaʻula a me nā huahana ʻē aʻe i hana ʻia mai nā holoholona hānai. Ma ʻAmelika Hui Pū ʻIa, hoʻomaka mau ka maʻi me ka nahu ʻana o ka Lone Star tick. Hoʻoili ka nahu i kahi molekala kō i kapa ʻia ʻo alpha-gal i loko o ke kino. I kekahi poʻe, hoʻoulu kēia i kahi pane mai nā pale o ke kino, i kapa ʻia hoʻi ʻo ka ʻōnaehana pale. Hana ia i nā maʻi ʻona māmā a hiki i ka nui i ka ʻiʻo ʻulaʻula, e like me ka pipi, puaʻa a i ʻole ke keiki hipa. Hiki nō hoʻi ke hana i nā maʻi ʻona i nā meaʻai ʻē aʻe mai nā holoholona hānai, e like me nā huahana waiū a i ʻole nā gelatin. Loaʻa ka Lone Star tick ma ka ʻākau hikina o ʻAmelika Hui Pū ʻIa. ʻOi aku ka nui o nā hihia o ka Alpha-gal syndrome i hōʻike ʻia ma ka hema, hikina a me waenakonu o ʻAmelika Hui Pū ʻIa. Akā, ke ʻike ʻia nei ka maʻi e pālahalaha aku ana i ka ʻākau a me ke komohana. Ke lawe nei nā hīnaʻi i ka Lone Star tick i nā wahi hou o ka ʻāina. Ke lawe nei nā ʻano ʻē aʻe o nā ticks i nā molekala alpha-gal i nā wahi ʻē aʻe o ka honua. Ua ʻike ʻia ka Alpha-gal syndrome ma nā wahi o ʻEulopa, ʻAusetalia, ʻAsia, ʻApelika Hema, a me ʻAmelika Hema a me Waena. Hiki i kekahi poʻe ke loaʻa ka Alpha-gal syndrome a ʻaʻole ʻike. Aia nā kānaka e loaʻa pinepine ana i nā maʻi ʻona nui, i kapa ʻia hoʻi ʻo nā maʻi anaphylactic, no kahi kumu maopopo ʻole. Hōʻike pū nā hoʻokolohua ʻaʻole lākou i loaʻa nā maʻi ʻai ʻē aʻe. Manaʻo nā mea noiʻi e pilikia kekahi o kēia poʻe i ka Alpha-gal syndrome. ʻAʻohe lāʻau lapaʻau ʻē aʻe ma mua o ka pale ʻana i ka ʻiʻo ʻulaʻula a me nā huahana ʻē aʻe i hana ʻia mai nā holoholona hānai. Inā loaʻa iā ʻoe kahi maʻi ʻona nui, pono paha ʻoe i ka lāʻau i kapa ʻia ʻo epinephrine a me ka mālama ʻana ma ka lumi pilikia. Pale i nā nahu tick e pale aku ai i ka Alpha-gal syndrome. E komo i nā lole lōʻihi a me nā pālule lōʻihi ke hele ʻoe i nā wahi ululāʻau a me nā wahi mauʻu. E hoʻohana i ka mea pale pepeke pū kekahi. E nānā i kou kino holoʻokoʻa no nā ticks ma hope o kou manawa ma waho.

ʻO ka maʻi ʻālohilohi alpha-gal, ʻoi aku ka lōʻihi o ka hoʻomaka ʻana o nā hōʻailona ma mua o nā maʻi ʻē aʻe o ka meaʻai. ʻO ka hapanui o nā pane i nā meaʻai maʻamau—e like me nā pīni a i ʻole nā ​​ʻanoʻano kai—e hana koke ma hope o kou hōʻike ʻana iā lākou. Ma ka maʻi alpha-gal, e ʻike ʻia nā pane ma kahi o 3 a 6 mau hola ma hope o kou hōʻike ʻana. ʻO nā meaʻai e hiki ke hoʻoulu i ka pane: ʻAi ʻulaʻula, e like me ka pipi, puaʻa a i ʻole ke keiki hipa. Nā ʻōpū o nā holoholona. Nā huahana i hana ʻia mai nā mammals, e like me nā gelatins a i ʻole nā ​​huahana waiū. Hiki i nā hōʻailona o ka maʻi alpha-gal ke komo pū me: Nā ʻōhule, ka ʻili ʻili, a i ʻole ka ʻili ʻili. Ka pehu ʻana o nā lehelehe, maka, alelo a me ka ʻāʻī, a i ʻole nā ​​ʻāpana kino ʻē aʻe. Ka wheezing a i ʻole ka pōkole o ka hanu. ʻO ka ʻeha o ka ʻōpū, ka luaʻi, ka ʻōpū ʻino a i ʻole ka luaʻi. ʻO ka manawa hoʻokaʻawale ma waena o ka ʻai ʻana i nā huahana ʻiʻo a me ka loaʻa ʻana o ka pane maʻi ʻālohilohi paha ke kumu i maopopo ʻole ai ka maʻi alpha-gal i ka wā mua. No ka laʻana, ʻaʻole maopopo ka pilina ma waena o kahi steak T-bone me ka ʻaina ahiahi a me nā ʻōhule i ka waenakonu o ka pō. Manaʻo nā mea noiʻi ua ʻike lākou i ke kumu o ka pane lohi. Wahi a lākou, ʻo ia ma muli o ka lōʻihi o ka hoʻoheheʻe ʻana o nā molekala alpha-gal ma mua o nā mea ʻē aʻe a komo i ka ʻōnaehana e hoʻoneʻe i ke koko ma ke kino. E kiʻi i ke kōkua inā loaʻa iā ʻoe nā hōʻailona maʻi ʻālohilohi ma hope o kou ʻai ʻana, ʻoiai he mau hola ma hope o kou ʻai ʻana. E ʻike i kāu mea mālama ola mua a i ʻole kahi loea maʻi ʻālohilohi, i kapa ʻia ʻo ka allergist. Mai kāpae i ka ʻiʻo ʻulaʻula ma ke ʻano he kumu hiki ke loaʻa i kāu pane. ʻOi aku ka nui o kēlā inā ʻoe e noho a i ʻole e hoʻolilo manawa i nā wahi o ka honua kahi i hōʻike ʻia ai ka maʻi alpha-gal. E kiʻi i ka mālama pilikia inā loaʻa iā ʻoe nā hōʻailona o ka pane maʻi ʻālohilohi koʻikoʻi e hoʻoulu i ka pilikia o ka hanu, i kapa ʻia ʻo anaphylaxis, e like me: Ka pilikia o ka hanu. Ka wikiwiki, nā ʻāpana nāwaliwali. Ka manaʻo dizziness a i ʻole ka māmā. Ka waimaka a me ka hiki ʻole ke ʻai. Ka ʻulaʻula a me ka mahana o ke kino holoʻokoʻa, i kapa ʻia ʻo flushing.

E kōkua inā loaʻa iā ʻoe nā hōʻailona o ka maʻi ʻai ma hope o ka ʻai ʻana, ʻoiai he mau hola ma hope o ka ʻai ʻana. E ʻike i kāu kauka mālama ola mua a i ʻole kahi loea maʻi ʻai, i kapa ʻia he allergist. Mai kāpae i ka ʻiʻo ʻulaʻula ma ke ʻano he kumu hiki ke loaʻa i kāu pane. ʻOi aku ka nui o kēlā inā noho ʻoe a i ʻole e hoʻolilo manawa ma nā wahi o ka honua kahi i hōʻike ʻia ai ka alpha-gal syndrome. E kiʻi i ka mālama pilikia inā loaʻa iā ʻoe nā hōʻailona o kahi pane maʻi ʻino e hoʻopilikia ana i ka hanu, i kapa ʻia ʻo anaphylaxis, e like me: ʻO ka pilikia o ka hanu. ʻO ka puʻuwai wikiwiki, nāwaliwali. ʻO ka manaʻo dizziness a i ʻole māmā. ʻO ka drooling a me ka hiki ʻole ke ʻai. ʻO ka ʻulaʻula a me ka mahana o ke kino holoʻokoʻa, i kapa ʻia ʻo flushing.

ʻO ka hapa nui o nā kānaka me ka alpha-gal syndrome ma ʻAmelika Hui Pū ʻIa e loaʻa ana i kēia kūlana i ka wā e nahu ʻia ai lākou e ka Lone Star tick. Hiki i nā nahu mai nā ʻano ʻē aʻe o nā ticks ke alakaʻi i kēia kūlana pū kekahi. ʻO kēia mau ticks ʻē aʻe ke kumu o ka alpha-gal syndrome ma nā ʻāpana o ʻEulopa, ʻAusetalia, ʻAsia, ʻApelika Hema, a me ʻAmelika Hema a me Waena. Manaʻo nā poʻe akamai he lawe nā ticks e hoʻokumu ana i ka alpha-gal syndrome i nā alpha-gal molecules. Mai ke koko o nā holoholona a lākou e nahu pinepine ai, e like me nā pipi a me nā hipa. I ka wā e nahu ai kahi tick e lawe ana i kēia mau molecules i ke kanaka, e hoʻouna aku ana ka tick i ka alpha-gal i loko o ke kino o ke kanaka. No nā kumu i ʻike ʻole ʻia, loaʻa i kekahi poʻe kahi pane pale ikaika i kēia mau molecules. Hana ke kino i nā protein i kapa ʻia ʻo nā antibodies. Hoʻopili kēia mau antibodies i ka alpha-gal ma ke ʻano he mea e pono ai ka ʻōnaehana pale e hoʻomaʻemaʻe. He ikaika loa ka pane, no laila ʻaʻole hiki i nā kānaka me kēia maʻi ʻai ke ʻai hou i ka ʻiʻo ʻulaʻula. ʻAʻole hiki iā lākou ke ʻai i nā meaʻai i hana ʻia mai nā mammals me ka ʻole o kahi maʻi ʻai. Hiki i nā kānaka i loaʻa nā nahu tick he nui ma mua o ka manawa ke loaʻa nā hōʻailona ʻino. Hiki i nā kānaka me nā antibodies e pili ana i ka alpha-gal syndrome ke loaʻa nā maʻi ʻai i ka lāʻau kanesa cetuximab (Erbitux). Hōʻike ka noiʻi e pili ana nā hihia o kēia maʻi lāʻau i ka alpha-gal syndrome. ʻIke ʻia nā antibodies a ka ʻōnaehana pale e hana ai i ka alpha-gal e pane i ke ʻano o ka lāʻau pū kekahi.

ʻAʻole i maopopo i nā mea lawelawe ola kino i kēia manawa ke kumu o ka loaʻa ʻana o ka alpha-gal syndrome i kekahi poʻe ma hope o ka hōʻike ʻia ʻana, a ʻaʻole i kekahi. ʻO ka maʻi nui loa ia ma ka hema, hikina a me waenakonu o ʻAmelika Hui Pū ʻIa. E kiʻekiʻe ana kou pilikia inā noho ʻoe a i ʻole e hoʻolilo manawa ma kēia mau wahi a: Hoʻolilo nui i ka manawa ma waho. Ua loaʻa iā ʻoe nā nahu ʻiole Lone Star he nui. I loko o nā makahiki 20 a 30 i hala iho nei, ua loaʻa ka ʻiole Lone Star i ka nui ma ka ʻākau e like me Maine. Ua loaʻa pū keia ʻiole ma ke komohana e like me waenakonu o Texas a me Oklahoma. Loaʻa pū ka alpha-gal syndrome ma nā wahi ʻē aʻe o ka honua. ʻO kēia ka hapa o ʻEulopa, ʻAusetalia, ʻAsia, ʻApelika Hema, a me ʻAmelika Hema a me Waena. Ma kēlā mau wahi, ʻike ʻia nā nahu mai kekahi ʻano o nā ʻiole e hoʻonui i ka pilikia o ka maʻi.

Hiki i ka Alpha-gal syndrome ke hoʻoulu i kahi maʻi ʻālohilohi koʻikoʻi i kapa ʻia ʻo ka anaphylaxis. Hiki ke make inā ʻaʻohe lāʻau lapaʻau. Hoʻōla ʻia ka anaphylaxis me ka lāʻau lapaʻau i kauoha ʻia e kapa ʻia ʻo epinephrine, i ʻike ʻia hoʻi ʻo adrenaline. Hiki iā ʻoe ke hāʻawi iā ʻoe iho i kahi pana o ka epinephrine me kahi mea hana i kapa ʻia ʻo ka auto-injector (EpiPen, Auvi-Q, a me nā mea ʻē aʻe). Pono nō hoʻi ʻoe e hele i ka lumi pilikia. ʻO nā hōʻailona o ka anaphylaxis e komo pū ai: Nā ala ea e pili ana, e hoʻonui iki. Ka pehu ʻana o ka ʻāʻī e paʻakikī ai ka hanu. Ka emi nui ʻana o ke kaomi koko, i kapa ʻia ʻo ka shock. Ka wikiwiki ʻana o ka naʻau. Ke manaʻo nei i ka dizziness a i ʻole ka māmā, a i ʻole ka hāʻule ʻana. Manaʻo nā mea mālama ola e noho ana kekahi poʻe i loaʻa pinepine i ka anaphylaxis a me ke kumu maopopo ʻole i ka alpha-gal syndrome. ʻAʻole lākou i ʻike ʻia.