He aha ka Brugada Syndrome? Nā Hōʻailona, Nā Kumu, & Lapaʻau

ʻO ka Brugada syndrome kahi maʻi naʻau maʻamau ʻole e pili ana i ke ʻano o ka holo ʻana o nā hōʻailona uila ma kou naʻau. Hiki i kēia kūlana genetic ke hoʻoulu i kou naʻau e pāʻani wikiwiki a ʻole paha, kahi e alakaʻi ai i ka hiolo ʻana a i ʻole, i nā hihia koʻikoʻi, ka hopu naʻau koke.

Ua wehewehe mua ʻia ke kūlana i ka makahiki 1992 e nā kauka Sepania ʻo Pedro a me Josep Brugada. Hoʻopili nui ia i ka ʻaoʻao ʻākau o ka ʻōnaehana uila o kou naʻau. ʻOiai ke kani nui nei, ʻo ka hoʻomaopopo ʻana i ka Brugada syndrome e kōkua iā ʻoe e hana pū me kāu hui mālama ola e hoʻokele pono ai.

He aha nā hōʻailona o ka Brugada syndrome?

ʻAʻole ʻike nui nā kānaka me ka Brugada syndrome i kekahi hōʻailona. I ka wā e loaʻa ai nā hōʻailona, pili pinepine lākou i nā ʻano naʻau ʻole e hiki ke koʻikoʻi loa.

Eia nā hōʻailona maʻamau loa āu e ʻike ai:

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• Ka hiolo koke ʻana a i ʻole nā ​​manawa kokoke i ka hiolo ʻana, ʻoi aku hoʻi i ka wā hoʻomaha a i ʻole hiamoe
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• Ka pāʻani naʻau a i ʻole ka manaʻo e holo wikiwiki ana kou naʻau a i ʻole ke kī ʻana i nā pā
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• Ka pilikia i ka hanu a i ʻole ka pōkole o ka hanu
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• ʻEha umauma a i ʻole ka ʻoluʻolu ʻole
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• Ka luhi a i ʻole ka māmā
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• Nā hanana like me ka hoʻopaʻa ʻana i ka wā hiolo
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ʻO ka ʻāpana paʻakikī e pili ana i ka Brugada syndrome, ʻo ia ka loaʻa pinepine ʻana o nā hōʻailona i ka wā hiamoe a i ʻole nā ​​manawa hoʻomaha, ma mua o ka wā hoʻoikaika kino. He ʻokoʻa kēia mai nā kūlana naʻau ʻē aʻe he nui. Loaʻa i kekahi poʻe ka mea i kapa ʻia ʻo

Hoʻokaʻina ʻia ka maʻi Brugada i nā ʻano like ʻole ma muli o ka hoʻololi kino kino kikoʻī i komo. ʻO ka ʻano maʻamau loa ka ʻAno 1, kahi e pili ana i ka 20-25% o nā hihia.

Hoʻopili ka maʻi Brugada ʻAno 1 i nā hoʻololi i loko o ka gene SCN5A, ka mea e kaohi ana i nā kahawai sodium i loko o nā sela o kou naʻau. Hoʻomaʻamaʻa kēia ʻano i nā ʻano hoʻoilina i ʻike maʻalahi ʻia a maʻalahi hoʻi ke ʻike ma o ka hoʻokolohua genetika.

Hoʻopili nā ʻano 2 a hiki i 12 i nā hoʻololi i nā gene ʻē aʻe e hoʻopilikia i nā kahawai ion ʻē aʻe i kou naʻau. He nui loa kēia mau ʻano a paʻakikī ke ʻike ma o ka hoʻokolohua genetika maʻamau. Hiki i kēlā me kēia ʻano ke loaʻa nā hōʻailona a me nā pae pilikia ʻokoʻa iki.

Eia naʻe, he mea nui e ʻike aia a hiki i ka 70% o nā kānaka me ka maʻi Brugada ʻaʻohe hoʻololi genetika i ʻike ʻia me nā ʻano hoʻokolohua o kēia manawa. ʻAʻole kēia manaʻo he emi iki ka ʻoiaʻiʻo a i ʻole ka koʻikoʻi - ʻo ia wale nō ka ʻike ʻana o nā ʻepekema i nā kumu genetika a pau i komo.

He aha ka mea e hoʻokumu ai i ka maʻi Brugada?

Hoʻokumu nui ʻia ka maʻi Brugada e nā hoʻololi genetika e hoʻopilikia i ke ala e neʻe ai nā hōʻailona uila ma o kou ʻiʻo naʻau. Hoʻopilikia kēia mau hoʻololi i ke kahe maʻamau o nā ions sodium, calcium, a i ʻole potassium ma o nā sela o kou naʻau.

E noʻonoʻo i ka ʻōnaehana uila o kou naʻau e like me ke kaula uila i loko o kou hale. Ke loaʻa ka pilikia me ka

• Ke kuni, ʻoi aku hoʻi nā kuni kiʻekiʻe ma luna o 102°F (39°C)
• Nā lāʻau lapaʻau kekahi, ʻoi aku hoʻi kekahi mau lāʻau antiarrhythmic, antidepressants, a me nā anesthetics
• Nā pilikia electrolyte, ʻoi aku hoʻi ka potassium haʻahaʻa a i ʻole ka calcium kiʻekiʻe
• Ka inu nui ʻana o ka waiʻona
• Ka hoʻohana ʻana i ka cocaine
• ʻAi nui a i ʻole ka nele o ka wai i kekahi mau hihia

He mea hoihoi, ʻaʻole like me nā kūlana naʻau he nui, ʻaʻole maʻamau ka hoʻoikaika kino e hoʻoulu i nā hōʻailona o ka maʻi Brugada. ʻO ka ʻoiaʻiʻo, ʻoi aku ka maʻamau o nā hōʻailona i ka wā hoʻomaha a i ʻole ka hiamoe ke emi iho ka wikiwiki o kou naʻau.

I ka wā e ʻike ai i ke kauka no ka maʻi Brugada?

Pono ʻoe e ʻimi i ka mālama ola kino koke inā loaʻa iā ʻoe nā hanana hāʻule, ʻoi aku hoʻi inā hana ʻia i ka wā hoʻomaha a i ʻole ka hiamoe. Pono e loiloi koke ʻia kekahi hanana o ka nalowale koke ʻana o ka ʻike.

Kāhea i ka 911 a i ʻole hele i ka lumi pilikia koke inā loaʻa iā ʻoe ka ʻeha umauma, ka pilikia nui o ka hanu, a i ʻole inā loaʻa i kekahi kanaka ʻoe i ka ʻike ʻole. Hiki i kēia ke lilo i mau hōʻailona o ka pilikia wikiwiki o ka naʻau e pono ai ka mālama koke.

Hoʻonohonoho i kahi hālāwai me kāu kauka inā ʻike ʻoe i nā palpitations naʻau hou, ka dizziness pinepine, a i ʻole inā loaʻa iā ʻoe ka mōʻaukala ʻohana o ka make naʻau koke, ʻoi aku hoʻi i nā poʻe ma lalo o 50. ʻOiai inā ʻano māmā kou mau hōʻailona, ʻoi aku ka maikaʻi o ka nānā ʻana iā lākou.

Pono ʻoe e ʻike i ke kauka inā lawe ʻoe i nā lāʻau lapaʻau a ʻike i nā hōʻailona naʻau hou. Hiki i kekahi mau lāʻau lapaʻau ke hoʻopilikia i ka maʻi Brugada, a pono paha kāu kauka e hoʻoponopono i kāu papahana mālama.

He aha nā mea pilikia no ka maʻi Brugada?

Hiki i kekahi mau mea ke hoʻonui i kou kūpono o ka loaʻa ʻana o ka maʻi Brugada a i ʻole ka loaʻa ʻana o nā hōʻailona inā loaʻa iā ʻoe ke kūlana. Ke hoʻomaopopo ʻana i kēia mau mea pilikia e kōkua iā ʻoe a me kāu kauka e loiloi pololei i kou kūlana.

ʻO nā mea pilikia nui e komo pū ana:

• Mōʻaukala ʻohana o ka maʻi Brugada a i ʻole ka make koke o ka naʻau i wehe ʻole ʻia
• Ke kāne (ʻoi aku ka nui o nā kāne ma 8-10 mau manawa ma mua o nā wāhine)
• Ke kūlana ʻAsia, ʻoiai ʻo ka ʻāina Hikina Hema a i ʻole Iapana
• Makahiki ma waena o 30-50 mau makahiki (ke ʻike pinepine ʻia nā hōʻailona)
• Loaʻa nā maʻi ʻē aʻe o ka naʻau
• Ke lawe nei i kekahi mau lāʻau lapaʻau e hoʻopilikia ana i ka naʻau

He mea hoihoi, ʻoiai hiki i nā wāhine ke hoʻoilina a lawe i ka mutation gene Brugada, ʻaʻole nui ka hiki ke loaʻa iā lākou nā hōʻailona. Manaʻo nā kānaka ʻepekema he mau hormones, ʻoiai ʻo ka estrogen, hiki ke pale aku i ka hopena o ke kūlana.

Hoʻopili pū nā kumu honua. ʻOi aku ka nui o ka maʻi Brugada ma kekahi mau wahi o ka honua, ʻoiai ʻo ka Hikina Hema o ʻAsia. Ma kekahi mau wahi o Thailand a me Laos, ua kapa ʻia ʻo ia ʻo "Sudden Unexplained Nocturnal Death Syndrome" a he kumu nui ia o ka make i nā kāne ʻōpio.

He aha nā pilikia hiki ke loaʻa i ka maʻi Brugada?

ʻO ka pilikia nui loa o ka maʻi Brugada, ʻo ia ka make koke o ka naʻau, hiki ke hoʻoweliweli i ke ola inā ʻaʻole mālama koke ʻia. Hana kēia i ka wā e loaʻa ai i kou naʻau kahi wikiwiki loa, chaotic rhythm e pale aku ai i ka hoʻopuka koko maikaʻi.

Loaʻa i nā kānaka me ka maʻi Brugada kekahi mau pilikia hiki ke loaʻa:

• Ventricular fibrillation (kahi naʻau chaotic, weliweli)
• Make koke o ka naʻau, ʻoiai i ka wā moe a i ʻole hoʻomaha
• Nā hanana fainting hou e hiki ke alakaʻi i nā hōʻeha mai nā hāʻule
• Atrial fibrillation (rhythm maʻamau ʻole i nā lumi luna o ka naʻau)
• Heart failure i nā hihia kakaikahi me nā hanana hou
• Ka hopena psychological mai ke ola ʻana me kahi kūlana hiki ke hoʻoweliweli i ke ola

ʻO ka nui o kēia mau pilikia e ʻokoʻa loa mai ke kanaka a ke kanaka. ʻAʻohe hōʻailona i loaʻa i kekahi poʻe me ka maʻi Brugada, ʻoiai he mau hanana weliweli ke ola o kekahi poʻe. Hiki i kāu kauka ke kōkua i ka loiloi ʻana i kou pilikia pilikino ma muli o kou kūlana kūikawā a me nā hopena hoʻokolohua.

He mea kūpono ke hoʻomaopopo aku, me ka mālama lapaʻau kūpono, nui nā kānaka me ka maʻi Brugada e ola ana i nā ola maʻamau a hana nui. ʻO ka mea nui, ʻo ia ka hana pili loa me ka loea rhythm naʻau e nānā i kou kūlana a lawe i nā palekana kūpono.

Pehea e ʻike ʻia ai ka maʻi Brugada?

ʻO ka ʻike ʻana i ka maʻi Brugada e pono ai ka hui ʻana o nā hoʻokolohua a me ka loiloi akahele e ka loea naʻau. ʻAʻole pololei mau ka ʻike ʻana no ka mea hiki ke intermittent ke kūlana a hiki ke hele mai a hele aku nā hōʻailona.

E hoʻomaka kāu kauka me ka moʻolelo lapaʻau kikoʻī a me ka nānā kino. E nīnau lākou e pili ana i kāu mau hōʻailona, ​​moʻolelo ʻohana, a me nā lāʻau āu e lawe nei. Kōkua kēia ʻike iā lākou e hoʻomaopopo i kāu mau mea pilikia a hoʻoholo i nā hoʻokolohua e pono ai.

ʻO nā hoʻokolohua ʻike nui e komo pū ana:

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• Electrocardiogram (ECG) e nānā i nā ʻano rhythm naʻau hiʻohiʻona
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• Hoʻokolohua hoʻoulu lāʻau me nā lāʻau lapaʻau e like me ka flecainide a i ʻole procainamide
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• Nānā Holter a i ʻole mea hoʻopaʻa hanana e hopu i nā rhythm naʻau ma ka manawa
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• Ke aʻo electrophysiology e loiloi i ka ʻōnaehana uila o kou naʻau
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• Hoʻokolohua genetika e nānā i nā mutations i ʻike ʻia
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• Nānā ʻohana inā loaʻa iā ʻoe nā ʻohana me ke kūlana
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He mea nui loa ka ECG no ka mea hiki iā ia ke hōʻike i kahi ʻano kikoʻī i kapa ʻia ʻo ka

I kekahi manawa, hoʻohana nā kauka i kahi hoʻokolohua lāʻau lapaʻau kahi e hāʻawi ai lākou iā ʻoe i kahi lāʻau e hiki ke hōʻike i ke ʻano Brugada inā loaʻa iā ʻoe ke kūlana. Hana ʻia kēia hoʻokolohua ma kahi haukapila me ka nānā pono ʻana no ka mea hiki ke hoʻoulu i nā leo pōʻino i nā poʻe me ka maʻi.

He aha ka lāʻau lapaʻau no ka maʻi Brugada?

Hoʻomaʻamaʻa ka lāʻau lapaʻau no ka maʻi Brugada i ka pale ʻana i nā leo naʻau pōʻino a me ka mālama ʻana i nā hōʻailona. Kaukaʻi ka papahana mālama kūikawā ma kāu pae pilikia, nā hōʻailona, ​​a me nā hopena hoʻokolohua.

No nā poʻe me ka pilikia nui o ka hopena naʻau koke, ʻo ka lāʻau lapaʻau nui kahi implantable cardioverter defibrillator (ICD). Nānā kēia mea hana liʻiliʻi i kou leo ​​naʻau a hāʻawi i kahi haʻalulu uila inā ʻike ʻia kahi leo pōʻino. ʻOiai hiki ke ʻoluʻolu ʻole ka haʻalulu, hiki ke ola.

ʻO nā koho mālama e komo pū me:

• Hoʻokomo ʻana i ka ICD no nā mea maʻi pilikia kiʻekiʻe
• Nā lāʻau lapaʻau e like me ka quinidine e kōkua i ka hoʻoikaika ʻana i nā leo naʻau
• Pale ʻana i nā mea hoʻoulu e like me kekahi mau lāʻau lapaʻau a me nā mahana wela kiʻekiʻe
• Nānā mau a me ka mālama hahai
• Hoʻololi ʻana i ke ola e hoʻemi i ka pilikia
• Kūkākūkā ʻohana a me ka hoʻokolohua genetika

ʻAʻole pono nā kānaka a pau me ka maʻi Brugada i kahi ICD. E loiloi kāu kauka i kāu pilikia pilikino ma muli o nā mea e like me ka loaʻa ʻana o nā hōʻailona, ​​kāu mau hopena hoʻokolohua, a me kāu mōʻaukala ʻohana. Hiki ke mālama ʻia kekahi poʻe me ka nānā pono a me ka pale ʻana i nā mea hoʻoulu i ʻike ʻia.

He mea nui hoʻi ka mālama lāʻau lapaʻau. E nānā kāu hui olakino i kāu mau lāʻau lapaʻau a pau e hōʻoia ʻaʻole hiki i kekahi o lākou ke hoʻopilikia i kou kūlana. E hāʻawi pū lākou iā ʻoe i kahi papa inoa o nā lāʻau lapaʻau e pale aku ai a e hōʻoia i ka ʻike ʻana o kāu poʻe lawelawe olakino a pau e pili ana i kou kūlana.

Pehea e mālama ai i ka maʻi Brugada ma ka home?

ʻO ka mālama ʻana i ka maʻi Brugada ma ka home, ʻo ia ka lawe ʻana i nā hana e pale aku ai i nā mea hoʻoulu a mākaukau no nā pilikia. ʻOiai paha he mea weliweli kēia, nui nā kānaka i hoʻokele pono i ko lākou kūlana me kekahi mau hoʻoponopono ola.

He mea nui ka mālama ʻana i ka wela no ka mea hiki i nā wela kiʻekiʻe ke hoʻoulu i nā leo weliweli. E mālama i nā lāʻau lapaʻau hoʻoemi wela e like me ka acetaminophen a i ʻole ibuprofen ma ka home, a kelepona i kāu kauka inā piʻi kou wela ma luna o 101°F (38.3°C). Mai ho'āʻo e

• Papa inoa piha o kāu mau lāʻau lapaʻau i kēia manawa, me nā mea hoʻohui pū kekahi
• Ka mōʻaukala olakino ʻohana, ʻoiai kekahi mau pilikia naʻau a i ʻole nā ​​make koke
• Ka wehewehe kikoʻī o kāu mau hōʻailona a me ka manawa e kū mai ai
• Nā nīnau āu e makemake ai e nīnau i kāu kauka
• Kekahi mau hopena ho'āʻo mua a i ʻole nā ​​moʻolelo lapaʻau
• ʻIke e pili ana i kou ʻano ola, me nā hana hoʻoikaika kino a me nā pae kaumaha

E noʻonoʻo e lawe mai i kahi hoa ʻohana a i ʻole hoaaloha i kāu kūkā. Hiki iā lākou ke kōkua iā ʻoe e hoʻomanaʻo i ka mea a ke kauka e ʻōlelo ai a hāʻawi i ke kākoʻo i ka wā e hiki mai ana i kahi kipa kaumaha. Hiki nō hoʻi ke kōkua ka loaʻa ʻana o kekahi ma laila inā pono ʻoe e kūkākūkā i ka nānā ʻana o ka ʻohana.

Mai kānalua e nīnau i nā nīnau i ka wā o kāu kipa. ʻO kēia kou manawa e hoʻomaopopo ai i kou kūlana a me nā koho mālama. E nīnau e pili ana i kekahi mea e hopohopo ai ʻoe, me nā hana palekana a me nā hōʻailona e pono ai ka nānā koke ʻana o nā kauka.

He aha ka mea nui e lawe aku e pili ana i ka maʻi Brugada?

ʻO ka maʻi Brugada he kūlana koʻikoʻi akā hiki ke mālama ʻia i ka naʻau e pili nui ana i ka ʻōnaehana uila o kou naʻau. ʻOiai hiki ke weliweli i ke ola, nui nā kānaka me kēia kūlana e ola ana i nā ola piha, hana me ka mālama lapaʻau kūpono a me ka hoʻokele ʻano ola.

ʻO ka mea nui loa e hoʻomanaʻo ai, ʻo ka ʻike mua ʻana a me ka mālama kūpono e hiki ai ke hoʻemi nui i kou pilikia o nā pilikia. Inā loaʻa iā ʻoe nā hōʻailona a i ʻole ka mōʻaukala ʻohana o ke kūlana, mai kali e ʻimi i ka loiloi lapaʻau.

ʻO ka hana pū ʻana me kahi loea naʻau he mea nui ia no ka hoʻokele pono ʻana i ka maʻi Brugada. Hiki iā lākou ke kōkua i ka hoʻoholo ʻana i kou pae pilikia pilikino a hoʻomohala i kahi papahana mālama kūpono iā ʻoe. ʻO ka mālama hoʻomau mau a me ka noʻonoʻo ʻana i kou kūlana he mea nui ia no ka hoʻokele holomua.

E hoʻomanaʻo ʻaʻole ʻo ka loaʻa ʻana o ka maʻi Brugada he manaʻo ia ʻaʻole hiki iā ʻoe ke ola i kahi ola maʻamau. Me nā palekana kūpono a me ka mālama lapaʻau, hiki i ka hapa nui o nā kānaka me ke kūlana ke hana, hoʻoikaika kino, a hauʻoli i kā lākou mau hana maʻamau. ʻO ke kī, ʻo ia ka noʻonoʻo mau, ka hahai ʻana i kāu papa hana lapaʻau, a me ka mālama ʻana i ka kamaʻilio ākea me kāu hui olakino.

Nā nīnau pinepine e pili ana i ka maʻi Brugada

Hiki i nā kānaka me ka maʻi Brugada ke hoʻoikaika kino me ka palekana?

ʻAe, hiki i ka hapa nui o nā kānaka me ka maʻi Brugada ke hoʻoikaika kino me ka palekana. ʻAʻole like me nā kūlana naʻau ʻē aʻe he nui, ʻaʻole pinepine nā hōʻailona o ka maʻi Brugada i ka wā o ka hana kino. Eia naʻe, pono ʻoe e kūkākūkā i kāu mau hoʻolālā hoʻoikaika kino me kāu kauka naʻau e hōʻoia ai he kūpono lākou no kāu kūlana kūikawā.

Hiki i kāu kauka ke ʻōlelo aku e pale aku i nā hana ikaika loa a i ʻole nā ​​haʻuki me ka pilikia kiʻekiʻe o ka hōʻeha inā loaʻa iā ʻoe kahi ICD. E kōkua lākou iā ʻoe e hoʻomohala i kahi papa hoʻoikaika kino e mālama iā ʻoe i ke olakino ʻoiai e hoʻemi ana i nā pilikia.

He mea hoʻoilina anei ka maʻi Brugada?

ʻAe, ʻo ka maʻi Brugada he kūlana genetic i hiki ke hoʻoili ʻia mai nā mākua i nā keiki. Loaʻa i kēlā me kēia keiki o kahi kanaka me ka maʻi Brugada kahi manawa 50% o ka hoʻoilina ʻana i ka mutation genetic. Eia naʻe, ʻaʻole hōʻoia ka loaʻa ʻana o ka mutation e ulu nā hōʻailona.

Hoʻomaopopo pinepine ʻia ka nānā ʻana i ka ʻohana i ka wā i ʻike ʻia ai kekahi me ka maʻi Brugada. Kōkua kēia e ʻike i nā lālā ʻohana ʻē aʻe i loaʻa paha i ke kūlana a pono i ka nānā ʻana a i ʻole ka mālama ʻana.

Hiki i nā lāʻau lapaʻau ke hoʻonāukiuki i nā hōʻailona o ka maʻi Brugada?

ʻAe, hiki i kekahi mau lāʻau lapaʻau ke hoʻonāukiuki i nā rhythm naʻau weliweli i nā kānaka me ka maʻi Brugada. ʻO kēia mau mea e komo pū ana i kekahi mau lāʻau antiarrhythmic, nā antidepressants tricyclic, a me kekahi mau anesthetics. E hāʻawi kāu kauka iā ʻoe i kahi papa inoa piha o nā lāʻau lapaʻau e pale aku ai.

E hoʻomaopopo mau i kekahi mea mālama ola e pili ana i kāu ʻike maʻi Brugada ma mua o kā lākou kau ʻana i nā lāʻau hou. Hoʻopili kēia i nā kauka niho, nā kauka ʻoki, a me nā loea ʻē aʻe paha ʻaʻole maopopo i kou kūlana.

He aha kāu e hana ai inā puhi kāu ICD?

Inā hāʻawi kāu ICD i kahi haʻalulu, e ho'āʻo e noho mālie a noho a moe i lalo koke. ʻO ka haʻalulu ke ʻike a mālama kāu mīkini i kahi helu puʻuwai weliweli. E kelepona koke i kāu kauka a i ʻole ke keʻena mīkini e hōʻike i ka haʻalulu a hoʻonohonoho i kahi hālāwai kūkākūkā.

Inā loaʻa iā ʻoe nā haʻalulu he nui a i ʻole ʻoe e ʻoluʻolu ʻole ma hope o ka haʻalulu, e ʻimi koke i ka mālama lapaʻau. E nānā kāu hui mīkini i ka ʻikepili mai kāu ICD e hoʻomaopopo i ka mea i hana a hoʻoholo inā pono kekahi hoʻoponopono.

Hiki i nā wāhine me ka maʻi Brugada ke loaʻa nā keiki me ka palekana?

ʻAe, hiki i nā wāhine he nui me ka maʻi Brugada ke loaʻa nā keiki me ka palekana, akā pono ka mālama pono ʻana i ka wā hāpai e kāu kauka naʻau a me kāu kauka hāpai. ʻO nā loli hormonal i ka wā hāpai e hāʻawi paha i ka palekana i nā hōʻailona maʻi Brugada.

E nānā pono kāu hui lapaʻau iā ʻoe i ka wā hāpai a me ka hānau ʻana. E kūkākūkā pū lākou i ka ʻōlelo aʻo genetics e kōkua iā ʻoe e hoʻomaopopo i nā pilikia o ka hoʻoili ʻana i ke kūlana i kāu mau keiki a me nā koho hoʻokolohua i loaʻa.