He aha ka Malignant Peripheral Nerve Sheath Tumor? Nā Hōʻailona, Nā Kumu, a me ka Lapaʻau

ʻO ka malignant peripheral nerve sheath tumor (MPNST) he ʻano maʻi kanesa kānalua loa ia e ulu ana ma ka pale ʻana a puni kou mau aʻalolo. E ulu ana kēia mau maʻi ma nā pūnaewele e hoʻopuni a kākoʻo i kou mau aʻalolo peripheral, ʻo ia nā aʻalolo ma waho o kou lolo a me kou kua.

ʻOiai hiki i kēia ʻike ke manaʻo nui, ʻo ka hoʻomaopopo ʻana i ka MPNST a pehea e mālama ʻia ai e kōkua iā ʻoe e ʻike hou aku i ka mākaukau. He 5-10% wale nō kēia mau maʻi o nā maʻi kanesa palupalu āpau, no laila ke hana nei ʻoe me kahi mea maʻamau ʻole akā hiki ke hoʻokele ʻia me ka mālama lapaʻau kūpono.

He aha nā hōʻailona o ka Malignant Peripheral Nerve Sheath Tumor?

ʻO ka hōʻailona mua loa kahi ʻāpana a i ʻole ka nui e ulu ana ma kahi ala aʻalolo e hiki ai a ʻaʻole paha ke kumu o ka ʻeha. Hiki iā ʻoe ke ʻike i kēia puʻupuʻu e ulu nui ana i nā hebedoma a i ʻole nā mahina, ʻokoʻa mai nā ulu maikaʻi ʻole e noho mau ana i ka nui like.

E nānā kākou i nā hōʻailona āu e ʻike ai, e hoʻomanaʻo ana i ka ʻike mua e hana maoli i ka ʻokoʻa i nā hopena lapaʻau.

• He ʻāpana paʻa, ulu nui a i ʻole ka puʻupuʻu ma lalo o kou ʻili
• ʻEha a i ʻole ka ʻeha ma ka wahi o ka maʻi
• Ka maʻi a i ʻole ka ʻōʻiliʻili ma ka wahi i hoʻolako ʻia e ka aʻalolo i pilikia
• Ka nāwaliwali i nā ʻiʻo i kaohi ʻia e ka aʻalolo i pilikia
• Ka nalowale o ka manaʻo a i ʻole ka manaʻo i nā ʻāpana o kou kino
• Nā loli i nā reflexes

I kekahi mau hihia, ʻaʻole paha ʻoe e ʻike i kekahi mau hōʻailona a hiki i ka ulu nui ʻana o ka maʻi e kaomi i nā pūnaewele e hoʻopuni ana. ʻO ia ke kumu e pono ai ke nānā aku i kekahi ʻāpana hou, ulu nui e kou kauka, ʻoiai inā ʻaʻole ia e ʻeha.

He aha nā ʻano o ka Malignant Peripheral Nerve Sheath Tumor?

Hoʻokaʻawale ʻia nā maʻi MPNST ma muli o kahi e ulu ai a me kā lākou mau kumu kumu. ʻO ka hoʻomaopopo ʻana i kēia mau ʻano e kōkua i kāu hui lapaʻau e koho i ke ala lapaʻau maikaʻi loa no kou kūlana kikoʻī.

Hoʻokaʻawale ka hapa nui o nā kauka i kēia mau maʻi i ʻelua mau hui nui ma muli o ko lākou kumu:

• Sporadic MPNST: E ulu kūlohelohe kēia me ka ʻole o ke kumu genetic i ʻike ʻia a hana i kahi 50% o nā hihia
• NF1-associated MPNST: E hana kēia i nā poʻe me ka neurofibromatosis type 1, e helu ana i kahi 40-50% o nā hihia
• Radiation-induced MPNST: E ulu kēia mau maʻi kānalua ma hope o ka mālama ʻana i ka radiation therapy

E hoʻokaʻawale pū kāu kauka i ka maʻi ma muli o kona papa, kahi e wehewehe ai i ka wikiwiki o nā cell kanesa ma lalo o ka microscope. ʻOi aku ka wikiwiki o ka ulu ʻana a me ka hoʻolaha ʻana o nā maʻi kiʻekiʻe ma mua o nā mea haʻahaʻa.

He aha ka mea e kumu ai i ka Malignant Peripheral Nerve Sheath Tumor?

ʻAʻole maopopo loa ke kumu pololei o ka MPNST, akā ua ʻike nā mea noiʻi i kekahi mau mea e hoʻonui ai i ka hiki ke loaʻa i kēia mau maʻi. ʻO ka hapa nui o nā hihia e hana me ka ʻole o ke kumu maopopo, ʻoiai kekahi e pili ana i nā kūlana genetic kikoʻī a i ʻole nā ​​mālama mua.

Eia nā mea nui e hiki ke kōkua i ka hoʻomohala ʻana o MPNST:

• Neurofibromatosis type 1 (NF1): E hoʻonui nui ana kēia kūlana genetic i kou pilikia
• Radiation therapy mua: Hiki i nā maʻi ke ulu 10-20 mau makahiki ma hope o ka mālama radiation
• Nā mutations genetic: Nā loli i nā genes kikoʻī e kaohi i ka ulu ʻana o nā cell
• Mōʻaukala ʻohana: Nā hihia kānalua e holo ana i nā ʻohana
• Nā maʻi aʻalolo maikaʻi ʻole mua: I kekahi manawa hiki i nā maʻi maikaʻi ʻole ke hoʻololi i nā mea ʻino

Inā loaʻa iā ʻoe ka NF1, ʻo kou pilikia ola holoʻokoʻa e loaʻa ai ka MPNST he 8-13% paha, ʻoi aku ka nui ma mua o ka lehulehu. Eia naʻe, ʻo ia hoʻi ʻaʻole loa e loaʻa i ka hapa nui o nā kānaka me NF1 kēia ʻano kanesa.

I ka wā hea e ʻike ai i ke kauka no ka Malignant Peripheral Nerve Sheath Tumor?

Pono ʻoe e hoʻokaʻaʻike i kāu kauka inā ʻike ʻoe i kekahi ʻāpana a i ʻole ka puʻupuʻu hou e ulu ana a i ʻole ke loli nei, ʻoi aku inā aia ma ke ala o kahi aʻalolo. ʻO ka loiloi mua e hāʻawi iā ʻoe i ka manawa maikaʻi loa no ka mālama holomua.

Mai kali inā ʻike ʻoe i kēia mau hōʻailona hōʻailona:

• He ʻāpana e ulu nui ana i ka manawa
• Ka maʻi hou a i ʻole ka nāwaliwali i kou mau lima a i ʻole nā ​​wāwae
• ʻEha e ulu nui ana a i ʻole ʻaʻole pane i nā mālama maʻamau
• Nā loli i ka manaʻo a i ʻole ka ʻōʻiliʻili e mau ana
• Kekahi mau loli hopohopo inā loaʻa iā ʻoe ka NF1

Inā loaʻa iā ʻoe ka neurofibromatosis type 1, he mea nui loa ia e loaʻa nā nānā maʻamau a hōʻike i nā loli i nā puʻupuʻu i loaʻa a i ʻole nā ​​hōʻailona hou. Hiki i kāu hui lapaʻau ke kōkua i ka hoʻokaʻawale ʻana ma waena o nā loli maikaʻi ʻole a me nā hōʻailona e pono ai ka nānā koke.

He aha nā mea pilikia no ka Malignant Peripheral Nerve Sheath Tumor?

Hiki i ka MPNST ke alakaʻi i nā pilikia he nui, mai ka maʻi ponoʻī a mai ka mālama ʻana. ʻO ka hoʻomaopopo ʻana i kēia mau mea hiki ke kōkua iā ʻoe e hoʻomākaukau a hana pū me kāu hui lapaʻau e hoʻemi i nā pilikia.

Hiki i nā pilikia mai ka maʻi ke komo pū:

• Ka poino o ka aʻalolo: Ka nalowale mau o ka hana i nā aʻalolo i pilikia
• Metastasis: Ke hoʻolaha nei ka maʻi i nā māmā, nā iwi, a i ʻole nā ​​mea'ē aʻe
• Local recurrence: Ke ulu hou nei ka maʻi ma ka wahi like
• Disability: Ka nalowale o ka neʻe ʻana a i ʻole ka manaʻo i nā wahi i pilikia
• ʻEha lōʻihi: Ka ʻoluʻolu mau mai ka pilikia o ka aʻalolo

Hiki i nā pilikia pili i ka mālama ke komo pū i nā pilikia ʻoki kino, nā hopena o ka chemotherapy, a i ʻole nā ​​hopena o ka radiation therapy. E kūkākūkā kāu hui lapaʻau i kēia mau mea hiki a hana e hoʻemi iā lākou ʻoiai e hoʻonui ana i nā pono mālama.

Pehea e ʻike ʻia ai ka Malignant Peripheral Nerve Sheath Tumor?

Pono ka ʻike ʻana i ka MPNST i nā ʻanuʻu he nui e hōʻoia i ka ʻike a hoʻoholo i ka nui o ka maʻi. E hoʻomaka kāu kauka me ka nānā kino a laila e kauoha i nā ho'āʻo kiko'ī e kiʻi i kahi kiʻi piha.

ʻO ke kaʻina hana diagnostic e komo pū me:

1. Nānā kino: E nānā kāu kauka i ka ʻāpana a me nā ho'āʻo hana aʻalolo
2. MRI scan: E hōʻike nā kiʻi kikoʻī i ka nui o ka maʻi a me ka pilina i nā aʻalolo
3. CT scan: Hiki ke hoʻohana ʻia e nānā i ka hoʻolaha ʻana i nā wahi ʻē aʻe
4. Biopsy: E hōʻoia kahi laʻana pūnaewele liʻiliʻi i ka ʻike
5. PET scan: I kekahi manawa e hoʻohana ʻia e nānā i ka hoʻolaha ʻana o ka maʻi kanesa
6. Genetic testing: Hiki ke kuhikuhi ʻia inā manaʻo ʻia ka NF1

ʻO ka biopsy ka ho'āʻo nui loa no ka mea ʻo ia wale nō ke ala e ʻike pono ai i ka MPNST. E hoʻolālā pono kāu kauka i kēia kaʻina hana e kiʻi i nā hopena pololei ʻoiai e hoʻemi ana i ka pilikia o ka hoʻolaha ʻana i nā cell kanesa.

He aha ka mālama ʻana no ka Malignant Peripheral Nerve Sheath Tumor?

ʻO ka mālama ʻana no ka MPNST e komo pinepine ana i ka ʻoki kino ma ke ʻano he ala nui, pinepine pū me nā therapies ʻē aʻe. E hoʻopilikino ʻia kāu hoʻolālā mālama i kou kūlana kikoʻī, me ka wahi o ka maʻi, ka nui, a inā ua hoʻolaha ʻia.

ʻO nā koho mālama nui e komo pū:

• ʻOki kino: Hoʻoneʻe piha ʻana i ka maʻi me nā palena ākea i ka hiki
• Radiation therapy: Nā kukuna ikehu kiʻekiʻe e pepehi i nā cell kanesa i koe
• Chemotherapy: Nā lāʻau lapaʻau e hoʻopili i nā cell kanesa ma kou kino holoʻokoʻa
• Nā ho'āʻo klinika: Ke komo nei i nā mālama hou, ho'āʻo
• Targeted therapy: Nā lāʻau e hoʻouka i nā hiʻohiʻona cell kanesa kikoʻī

ʻO ka ʻoki kino ka mālama mua a me ka mea nui loa. E ho'āʻo kāu kauka e hoʻoneʻe i ka maʻi holoʻokoʻa me kekahi mau pūnaewele olakino e hoʻopuni ana e hōʻoia i ka pau ʻana o nā cell kanesa āpau. I kekahi manawa hiki i kēia ke manaʻo i ka mōhai ʻana i kekahi hana aʻalolo, akā e kūkākūkā kāu hui i kēia mau kālepa me ʻoe.

No nā maʻi hiki ʻole ke hoʻoneʻe piha ʻia a i ʻole ua hoʻolaha ʻia, hiki i kāu kauka ke kuhikuhi i ka chemotherapy a i ʻole ka radiation therapy. Hiki i kēia mau mālama ke kōkua i ka hoʻemi ʻana i nā maʻi, hoʻolohi i ko lākou ulu ʻana, a i ʻole hoʻemi i nā hōʻailona.

Pehea e hoʻokele ai i nā hōʻailona ma ka home i ka wā o ka mālama ʻana i ka Malignant Peripheral Nerve Sheath Tumor?

ʻO ka hoʻokele ʻana i nā hōʻailona ma ka home he ʻāpana nui ia o kāu hoʻolālā mālama holoʻokoʻa. Hiki i nā hoʻolālā maʻalahi ke kōkua iā ʻoe e ʻoluʻolu hou a mālama i kou ola maikaʻi i ka wā o ka mālama ʻana.

Eia nā ala e hoʻokele ai i nā hōʻailona maʻamau:

• Pain management: E hoʻohana i nā lāʻau lapaʻau i kuhikuhi ʻia e like me ke kuhikuhi ʻia a ho'āʻo i ka hoʻomehana māmā a i ʻole ka mālama anu
• Fatigue: E kaulike i ka hana me ka hoʻomaha a mālama i ka papa moe maʻamau
• Nutrition: E ʻai i nā meaʻai liʻiliʻi, pinepine a noho hydrated
• Gentle exercise: Ka hele wāwae māmā a i ʻole ka hoʻolōʻihi e like me ka ʻae ʻana o kāu kauka
• Stress management: E hoʻomaʻamaʻa i nā ʻano hoʻomaha a i ʻole ka noʻonoʻo
• Skin care: E mālama i ka wahi ʻoki maʻemaʻe a maloʻo

E nīnau mau i kāu hui lapaʻau ma mua o ka ho'āʻo ʻana i nā ala hou e hoʻokele ai i nā hōʻailona. Hiki iā lākou ke alakaʻi iā ʻoe i ka mea palekana a maikaʻi no kou kūlana kikoʻī.

Pehea ʻoe e hoʻomākaukau ai no kāu kauka appointment?

ʻO ka hoʻomākaukau ʻana no kāu appointment e kōkua e hōʻoia i ka loaʻa ʻana o ka nui loa o kou manawa me kāu kauka. ʻO ka hele ʻana i ka hoʻonohonoho ʻana me nā nīnau a me nā ʻike e hana i ka kipa hou aku no nā mea āpau.

Ma mua o kāu appointment:

1. E kākau i kou mau hōʻailona: E komo pū i ka manawa i hoʻomaka ai lākou a pehea lākou i loli ai
2. E papa inoa i kou mau lāʻau lapaʻau: E komo pū nā mea hoʻohui a me nā lāʻau lapaʻau ma luna o ka counter
3. E hōʻiliʻili i nā moʻolelo lapaʻau: E lawe mai i nā hopena ho'āʻo mua a me nā haʻawina imaging
4. E hoʻomākaukau i nā nīnau: E kākau i ka mea āu e makemake ai e ʻike e pili ana i kou kūlana
5. E lawe mai i ke kākoʻo: E noʻonoʻo e hele mai kekahi lālā ʻohana a hoaaloha pū me ʻoe
6. E hoʻomaopopo i ka mōʻaukala ʻohana: E komo pū i kekahi mau hoahānau me ka maʻi kanesa a i ʻole nā ​​kūlana genetic

Mai kānalua e nīnau e pili ana i kekahi mea āu i ʻike ʻole ai. Makemake kāu hui lapaʻau e kōkua iā ʻoe e ʻike a ʻoluʻolu me kāu hoʻolālā mālama.

He aha ka mea nui e pili ana i ka Malignant Peripheral Nerve Sheath Tumor?

ʻO ka MPNST he ʻano maʻi kanesa kānalua akā koʻikoʻi ia e pono ai ka nānā koke a me ka mālama kūikawā. ʻOiai hiki i ka ʻike ke manaʻo nui, nui nā kānaka e hoʻokele holomua i kēia kūlana me ka mālama kūpono.

ʻO nā mea nui loa e hoʻomanaʻo ai ʻo ka ʻike mua e hoʻomaikaʻi i nā hopena, ke hoʻomaikaʻi mau nei nā koho mālama, a ʻaʻole pono ʻoe e kū i kēia wale nō. Loaʻa i kāu hui lapaʻau ka ʻike me ka MPNST a hiki iā lākou ke alakaʻi iā ʻoe ma kēlā me kēia ʻanuʻu o kāu mālama.

E noho pili me kāu poʻe lawelawe olakino, mai kānalua e nīnau i nā nīnau, a e kālele i ka lawe ʻana i nā mea hoʻokahi i ka manawa. Me ka mālama lapaʻau kūpono a me ke kākoʻo, hiki iā ʻoe ke hana i ka hopena maikaʻi loa no kou kūlana.

Nā nīnau pinepine e pili ana i ka Malignant Peripheral Nerve Sheath Tumor

Q1: Pehea ka kānalua o ka malignant peripheral nerve sheath tumor?

He kānalua loa ka MPNST, e hana ana i kahi 5-10% wale nō o nā soft tissue sarcomas āpau. E hana ia ma kahi o 1 i 100,000 mau kānaka i kēlā me kēia makahiki i ka lehulehu. Eia naʻe, inā loaʻa iā ʻoe ka neurofibromatosis type 1, ʻoi aku ka nui o kou pilikia ma kahi o 8-13% ma kou ola holoʻokoʻa.

Q2: Hiki ke ho'ōla ʻia ka MPNST?

Ke hilinaʻi nei ka manaʻo i nā mea he nui e komo pū ana i ka nui o ka maʻi, ka wahi, a inā ua hoʻolaha ʻia. Ke hopu ʻia i ka wā mua a hoʻoneʻe piha ʻia me ka ʻoki kino, nui nā kānaka e hana maikaʻi. Eia naʻe, hiki i ka MPNST ke ʻino, no laila he mea nui ka nānā mau ʻana a i kekahi manawa nā mālama hou aku no ka holomua lōʻihi.

Q3: ʻO ka loaʻa ʻana o ka neurofibromatosis ke ʻano e loaʻa iaʻu ka MPNST?

ʻAʻole, ʻaʻole ke ʻano o ka loaʻa ʻana o ka NF1 e loaʻa nō ʻoe i ka MPNST. ʻOiai ke hoʻonui nui nei ka NF1 i kou pilikia i hoʻohālikelike ʻia i ka lehulehu, ʻaʻole loa e loaʻa i ka hapa nui o nā kānaka me NF1 kēia ʻano kanesa. ʻO ka nānā mau ʻana e kōkua i ka hopu ʻana i nā loli mua inā hana lākou.

Q4: Pehea ka wikiwiki o ka ulu ʻana o kēia mau maʻi?

ʻO nā wikiwiki ulu MPNST he ʻokoʻa loa. ʻO kekahi e ulu mālie ana i nā mahina a i nā makahiki, ʻoiai kekahi e hiki ke ulu wikiwiki i nā hebedoma. Pono e loiloi ʻia kekahi ʻāpana e ulu nui ana a i ʻole ke loli nei e ke kauka, ʻaʻole pono ke wikiwiki o ka loli.

Q5: He aha ka ʻokoʻa ma waena o ka MPNST a me kahi maʻi aʻalolo maikaʻi ʻole?

ʻO nā maʻi aʻalolo maikaʻi ʻole e ulu mālie ana, e noho mau ana i ka nui like no nā manawa lōʻihi, a ʻaʻole pinepine e kumu i nā hōʻailona nui. ʻOi aku ka wikiwiki o ka ulu ʻana o ka MPNST, hiki ke kumu i ka ʻeha a i ʻole nā ​​hōʻailona aʻalolo, a loaʻa ka hiki ke hoʻolaha i nā ʻāpana ʻē aʻe o ke kino. ʻO ka biopsy wale nō ka mea hiki ke haʻi pololei i ka ʻokoʻa ma waena o nā mea ʻelua.