He aha ka MEN-1? Nā hōʻailona, nā kumu, a me ka mālama

ʻO ka Multiple Endocrine Neoplasia Type 1 (MEN-1) kahi maʻi genetika kānalua e hoʻoulu ai i nā ʻōpū e ulu i loko o nā gland e hana ana i nā hormones ma kou kino. ʻO ka maʻamau, he benign kēia mau ʻōpū, ʻo ia hoʻi ʻaʻole lākou he kanesa, akā hiki iā lākou ke hoʻopilikia i ke ʻano o ka hana ʻana a me ka hoʻohana ʻana o kou kino i nā hormones.

E noʻonoʻo i kāu ʻōnaehana endocrine e like me ka pūnaewele leka o kou kino, me nā gland e hoʻokuʻu ana i nā hormones e kaohi i nā mea a pau mai ke kō koko a hiki i ka ikaika o nā iwi. Ke loaʻa iā ʻoe ka MEN-1, hiki i kēia pūnaewele ke hoʻomohala i nā ulu e hoʻopilikia i ka hana maʻamau o ka hormone, e alakaʻi ana i nā hōʻailona like ʻole e like ʻole paha i ka wā mua.

He aha ka MEN-1?

He syndrome hoʻoilina ka MEN-1 e pili nui ana i ʻekolu wahi nui o kou kino: nā parathyroid glands ma kou ʻāʻī, ka pancreas, a me ka pituitary gland ma kou lolo. Loaʻa i kēia kūlana kona inoa no ka mea e pili ana i nā gland endocrine he nui e hoʻomohala ana i ka neoplasia, ʻo ia ka huaʻōlelo lapaʻau no ka ulu ʻana o nā pūnaewele kūpono ʻole.

Hoʻopili kēia kūlana i kahi 1 i 30,000 mau kānaka, e lilo ana i mea kānalua loa. ʻO ka mea e hoʻopilikia ai ka MEN-1, ʻo ia ka hiki iā ia ke hoʻoulu i nā hōʻailona like ʻole i nā kānaka like ʻole, ʻoiai ma loko o ka ʻohana hoʻokahi.

ʻO nā ʻōpū e pili ana i ka MEN-1 e ulu mālie ana i ka manawa. ʻOiai ʻo ka hapanui he benign, hiki iā lākou ke hoʻoulu i nā pilikia olakino nui ma o ka hana ʻana i ka nui o kekahi mau hormones a i ʻole ma o ka ulu ʻana i ka nui e kaomi ai i nā ʻōnaehana kokoke.

He aha nā hōʻailona o ka MEN-1?

Hiki i nā hōʻailona o ka MEN-1 ke ʻokoʻa loa no ka mea e hilinaʻi ana lākou i nā gland i pilikia a me ka nui o ka hormone a lākou e hana nei. ʻAʻole ʻike ka nui o nā kānaka i loaʻa iā lākou ka MEN-1 a hiki i ko lākou wā makua, no ka mea e ulu mālie ana nā hōʻailona i nā makahiki.

No ka mea ʻoi aku ka maʻamau o ka hoʻopili ʻana o ka MEN-1 i kāu mau parathyroid glands, hiki iā ʻoe ke ʻike mua i nā hōʻailona e pili ana i nā kiʻekiʻe o ka calcium i loko o kou koko:

• Pōhaku kīkī e hoʻomau mau ana
• ʻEha iwi a i ʻole nā ​​haʻihaʻi e maʻalahi ke hana
• Luhi ʻaʻole e hoʻomaikaʻi me ka hoʻomaha
• Kaumaha a i ʻole nā ​​hoʻololi manaʻo
• Nawaliwali o nā ʻiʻo
• Makewai nui a me ka mimi nui
• Nausea a i ʻole ka ʻōpū ʻino
• Nā pilikia hoʻomanaʻo a i ʻole ka huikau

Ke hoʻopilikia nei ka MEN-1 i kāu pancreas, hiki iā ʻoe ke ʻike i nā hōʻailona e pili ana i nā pilikia o ka hormone ma laila. Inā ulu nā tumors e hana ana i ka insulin, hiki iā ʻoe ke loaʻa nā manawa o ke kō koko haʻahaʻa weliweli me nā hōʻailona e like me ka hou, ka haʻalulu, ka puʻuwai wikiwiki, a i ʻole nā ​​manawa hiolo.

Ke ulu nei kekahi poʻe i nā tumors e hana ana i ka gastrin, kahi hormone e hoʻonui i ka waikawa o ka ʻōpū. Hiki i kēia ke alakaʻi i nā ʻōpū ʻōpū koʻikoʻi, ka puʻuwai mau, ka maʻi ʻōpū, a i ʻole ka ʻeha ʻōpū ʻaʻole e pane maikaʻi i nā lāʻau lapaʻau maʻamau.

Inā pili ka pituitary gland, hiki iā ʻoe ke ʻike i nā hōʻailona e like me nā poʻo ʻeha mau, nā loli ʻike, a i ʻole nā ​​pilikia me ka ulu ʻana a me ka hoʻomohala moekolohe. Ke ʻike nei kekahi poʻe i nā manawa menstrual kūpono ʻole, ka emi ʻana o ka makemake moekolohe, a i ʻole ka hana waiū i manaʻo ʻole ʻia mai nā umauma.

I nā hihia kakaikahi, hiki i ka MEN-1 ke hoʻopilikia i nā ʻāpana ʻē aʻe o kou kino, e hana ana i nā ulu ʻili, nā tumors māmā, a i ʻole nā ​​tumors i kāu mau glands adrenal. ʻOi aku ka liʻiliʻi o kēia mau pilikia akā hiki ke hana i ka holomua o ke kūlana.

He aha ka mea e hana ai i ka MEN-1?

Hoʻokumu ʻia ka MEN-1 e nā mutations i ka gene MEN1, ka mea maʻamau e kōkua i ka pale ʻana i nā tumors mai ka ulu ʻana i kāu mau glands endocrine. Ke hana pono ʻole kēia gene, hiki i nā cell i kēia mau glands ke ulu ma waho o ke kaohi, e hana ana i nā tumors i ʻike ʻia o kēia kūlana.

Hoʻoili ʻia kēia hoʻololi genetic i ka mea a nā kauka i kapa ai he ʻano autosomal dominant. ʻO ia hoʻi, pono ʻoe e hoʻoili i hoʻokahi kope o ka gene mutated mai kekahi makua e hoʻomohala i ka MEN-1. Inā loaʻa i kekahi o kou mau mākua ka MEN-1, loaʻa iā ʻoe ka 50% manawa e hoʻoili ai i ke kūlana.

Ma kahi o 10% o nā hihia, ulu mai ka MEN-1 ma ke ʻano he mutation hou, ʻo ia hoʻi ʻaʻohe o nā mākua i loaʻa ka maʻi. Ua kapa ʻia kēia mau hihia he de novo mutations, a hana kūlohelohe lākou i ka wā o ka hoʻokumu ʻana o nā cell hanau a i ʻole ka hoʻomohala mua.

Hoʻopuka ka gene MEN1 i kahi protein i kapa ʻia ʻo menin, kahi e hana ai e like me ka mea kiai i loko o kou mau cell. Kōkua ka menin i ka kaohi ʻana i ka māhele ʻana o nā cell a pale aku i nā cell mai ka ulu wikiwiki ʻana. Ke hōʻino ʻia ka gene, hāʻule kēia hana pale, e ʻae ana i ka ulu ʻana o nā tumor i nā tissues e hana ana i nā hormone.

I ka wā hea e ʻike ai i ke kauka no ka MEN-1?

Pono ʻoe e hoʻokaʻaʻike i kāu kauka inā loaʻa iā ʻoe nā pōhaku kidney e hoʻi hou mai ana, ʻoi aku inā ʻōpio ʻoe a i ʻole inā hoʻomau lākou e hoʻi mai ma waho aʻe o ka mālama ʻana. ʻO nā pōhaku kidney pinepine i hui pū ʻia me nā pilikia iwi a i ʻole ka luhi mau loa paha e hōʻailona i kahi pilikia me kou mau parathyroid glands.

E ʻimi i ka mālama lapaʻau inā loaʻa iā ʻoe nā manawa o ka hou, haʻalulu, wikiwiki o ka puʻuwai, a i ʻole ka huikau e hōʻike paha i nā hāʻule weliweli i ke kō koko. ʻO kēia mau hōʻailona, ʻoi aku inā loaʻa lākou i ka wā ʻaʻole ʻoe i ʻai, pono e loiloi koke.

E hoʻonohonoho i kahi manawa inā loaʻa iā ʻoe nā ʻōpū ʻōpū ʻaʻole e ho'ōla me ka mālama maʻamau, a i ʻole inā loaʻa iā ʻoe ka heartburn mau loa me ka diarrhea a me ka ʻeha ʻōpū. ʻO kēia hui o nā hōʻailona e hōʻike paha i nā tumor e hana ana i nā hormone i loko o kou pancreas.

E hoʻokaʻaʻike i kāu mea lawelawe olakino inā loaʻa iā ʻoe nā poʻo ʻeha mau loa me nā loli ʻike, ʻoiai hiki i kēia ke hōʻailona i kahi tumor pituitary. Pēlā nō, inā ʻike ʻoe i nā loli i manaʻo ʻole ʻia i kāu mau manawa menstrual, sex drive, a i ʻole ka hana waiū umauma, hiki i kēia ke lilo i mau hōʻailona o ka pili ʻana o ka pituitary.

Inā loaʻa iā ʻoe kahi moʻolelo ʻohana o ka MEN-1 a i ʻole nā ​​kūlana pili, he mea nui ia e kūkākūkā i ka hoʻokolohua gene a me ka nānā ʻana me kāu kauka, ʻoiai inā ʻaʻohe ou hōʻailona i kēia manawa. Hiki i ka ʻike mua ke kōkua i ka pale ʻana i nā pilikia a alakaʻi i ka nānā kūpono.

He aha nā mea pilikia no ka MEN-1?

ʻO ka mea pilikia nui loa no ka MEN-1, ʻo ia ka loaʻa ʻana o ka makua me ke kūlana. Ma muli o ka hahai ʻana o ka MEN-1 i kahi ʻano hoʻoilina autosomal dominant, loaʻa i nā keiki o nā mākua i pilikia ka 50% o ka manawa e hoʻoilina ai i ka mutation genetic.

ʻO ka loaʻa ʻana o ka mōʻaukala ʻohana o nā tumors hormone-related kūikawā, ʻoiai inā ʻaʻole i ʻike ʻia ma ke ʻano he MEN-1, hiki ke hoʻonui i kou pilikia. I kekahi manawa, ʻike ʻole ʻia ke kūlana i nā ʻohana no nā hanauna, ʻoiai inā he māmā nā hōʻailona a i ʻole i hoʻopaʻa ʻia i nā kumu ʻē aʻe.

ʻAʻole like me nā kūlana ʻē aʻe he nui, ʻaʻohe pilikia pili i ke ola o ka MEN-1. ʻAʻole pili kou ʻai, nā hana hoʻoikaika kino, nā hōʻike kaiapuni, a i ʻole nā ​​koho pilikino i ka hoʻomohala ʻana i kēia kūlana genetic.

Hiki i ka makahiki ke hoʻopilikia i ka hōʻike ʻana o nā hōʻailona, ​​akā ʻaʻole ia e hoʻololi i kou pilikia o ka loaʻa ʻana o ke kūlana. Hoʻomohala ka hapa nui o nā kānaka me ka MEN-1 i nā hōʻailona ma waena o nā makahiki 20 a me 40, ʻoiai ʻaʻole hiki i kekahi ke hōʻike i nā hōʻailona a hiki i ka wā ma hope a i ʻole, ma kahi ʻano liʻiliʻi, i ka wā kamaliʻi.

ʻAʻole pili nui ka wahine i kou pilikia o ka hoʻoilina ʻana i ka MEN-1, ʻoiai hiki i kekahi mau hōʻailona ke hōʻike ʻokoʻa i nā kāne a me nā wāhine ma muli o nā ʻokoʻa hormonal.

He aha nā pilikia hiki ke loaʻa i ka MEN-1?

Hiki i nā pilikia o ka MEN-1 ke koʻikoʻi a pili pinepine i nā hopena lōʻihi o nā pilikia hormonal a i ʻole ke alo kino o ka ulu ʻana o nā tumors. ʻO ka hoʻomaopopo ʻana i kēia mau pilikia hiki ke kōkua iā ʻoe a me kāu hui mālama ola e makaʻala no nā pilikia.

Hiki i nā kiʻekiʻe calcium mai nā parathyroid glands i hana nui ʻia ke alakaʻi i kekahi mau pilikia pilikia:

• Osteoporosis koʻikoʻi a me ka hoʻonui ʻana i ka pilikia o ka haki
• Kidney disease maʻi ma muli o nā pōhaku kidney i hana hou ʻia
• Nā pilikia o ka rhythm naʻau mai nā pilikia calcium
• Kaumaha koʻikoʻi a i ʻole ka hoʻohaʻahaʻa ʻana o ka naʻauao
• Gastric ulcers e hiki ke perforate a i ʻole ke kahe koko

Hiki i nā ʻōpū pancreatic ke hoʻopilikia i ka emi koke ʻana o ke kō koko e hiki ai ke alakaʻi i ka loaʻa ʻana o nā maʻi ʻeha, coma, a i ʻole ka pōʻino mau loa i ka lolo inā ʻaʻole i mālama koke ʻia. Hoʻopuka kekahi mau ʻōpū pancreatic i ka gastrin nui loa, e alakaʻi ana i nā ʻōpū koʻikoʻi e hiki ke perforation i ka ʻōpū a i ʻole ka ʻōpū.

Hiki i nā ʻōpū pituitary ke ulu nui e kaomi i nā ʻāpana kokoke, e hiki ai ke alakaʻi i ka nalowale mau loa o ka ʻike a i ʻole nā ​​kūpono hormonal koʻikoʻi. Hiki i nā ʻōpū pituitary nui ke hoʻonui i ke kaomi i loko o kou poʻo, e alakaʻi ana i nā headaches mau a me nā pilikia neurological.

ʻOiai he nui nā MEN-1 tumors he benign, aia kahi pilikia liʻiliʻi e hiki ai ke lilo i kanesa i ka manawa. ʻO nā ʻōpū pancreatic ka mea kiʻekiʻe loa o ka hoʻololi malignant, ʻo ia ke kumu o ka pono o ka nānā mau.

I nā hihia kakaikahi, hiki i ka MEN-1 ke hoʻokumu i nā ʻōpū i nā māmā, thymus, a i ʻole nā ​​glands adrenal. Hiki i kēia mau pilikia maʻamau ʻole ke koʻikoʻi a pono paha i nā ala mālama kūikawā.

Pehea e ʻike ʻia ai ka MEN-1?

ʻO ka ʻike ʻana i ka MEN-1 e pili ana i ka hui ʻana o ka loiloi lapaʻau, nā hoʻokolohua lapaʻau, nā haʻawina kiʻi, a me ka hoʻokolohua gene. E hoʻomaka kāu kauka ma ka nānā ʻana i kou mau hōʻailona a me ka mōʻaukala ʻohana e hoʻoholo inā he hiki ke MEN-1.

He mea nui nā hoʻokolohua koko no ka ʻike ʻana a maʻamau e komo pū me ka nānā ʻana i ka calcium, parathyroid hormone, a me nā hormone pancreatic like ʻole. ʻO ka calcium kiʻekiʻe me nā pae parathyroid hormone kiʻekiʻe e hāʻawi pinepine i ka ʻike mua e hiki ke loaʻa ka MEN-1.

Hiki i kāu kauka ke kauoha i nā hoʻokolohua hormone hou aku, me ka gastrin, insulin, glucagon, a me nā hormone pituitary. Kūkulu kēia mau hoʻokolohua i ka ʻike ʻana i nā glands i pilikia a me ka nui o ka hana nui ʻana o nā hormone.

Kōkua nā haʻawina kiʻi e ʻike i nā ʻōpū a loiloi i ko lākou nui. Hiki iā ʻoe ke loaʻa nā scans CT, nā scans MRI, a i ʻole nā ​​scans lāʻau lapaʻau nuklea kūikawā e hiki ke ʻike i nā ʻōpū liʻiliʻi e hana ana i nā hormone e hiki ʻole ke ʻike ʻia ma nā kiʻi maʻamau.

Hiki i ka ho'okolohua gene ke hōʻoia i ka maʻi ma ka ʻike ʻana i nā loli i loko o ka gene MEN1. He waiwai loa kēia ho'okolohua no nā lālā o ka ʻohana e makemake ana e ʻike inā lawe lākou i ka loli gene, ʻoiai inā ʻaʻohe o lākou hōʻailona.

Hoʻomaopopo pinepine ʻia ka maʻi ke loaʻa iā ʻoe nā ʻōpū ma ka liʻiliʻi ʻelua o nā ʻāpana kumu ʻekolu (parathyroid, pancreas, a i ʻole pituitary) a i ʻole ke hōʻike mai ka ho'okolohua gene i kahi loli gene MEN1.

He aha ka lāʻau lapaʻau no ka MEN-1?

Kūpono ka lāʻau lapaʻau no ka MEN-1 i ka mālama ʻana i nā pilikia hormone a me ka hoʻoponopono ʻana i nā ʻōpū pilikino e like me ko lākou ulu ʻana. ʻOiai he kūlana ola lōʻihi kēia, e ulu paha kāu papahana lapaʻau ma mua o ka manawa e like me ka puka ʻana mai o nā ʻōpū hou a i ʻole ka ulu ʻana o nā mea i loaʻa.

No nā gland parathyroid i hana nui, ʻo ka ʻoki kino ka lāʻau lapaʻau makemake pinepine ʻia. E wehe pinepine kāu kauka ʻoki kino i ʻekolu a me ka hapa o kāu mau gland parathyroid ʻehā, e waiho ana i ka lauoho lawa e mālama i nā pae calcium maʻamau ʻoiai e pale aku i ke kūlana mai ka hoʻi hou koke ʻana.

Pono nā ʻōpū pancreatic i ka lāʻau lapaʻau pilikino ma muli o ko lākou nui, wahi, a me ka hana hormone. Hiki ke nānā wale ʻia nā ʻōpū liʻiliʻi, ʻaʻohe hana, ʻoiai pono pinepine ka wehe ʻana i nā ʻōpū nui a i ʻole nā ​​​​hormone-hana.

Inā loaʻa iā ʻoe nā ʻōpū hana-insulin e hoʻopilikia ana i ke kō koko haʻahaʻa weliweli, hiki i kāu kauka ke kuhikuhi i nā lāʻau lapaʻau e like me ka diazoxide e kōkua i ka mālama ʻana i nā pae kō koko paʻa. No nā ʻōpū hana-gastrin, hiki i nā mea hoʻoemi proton pump ke kōkua i ka kaohi ʻana i ka hana waikawa ʻōpū.

Hoʻoponopono pinepine ʻia nā ʻōpū pituitary me nā lāʻau lapaʻau e hiki ke hoʻemi i kekahi mau ʻano o nā ʻōpū a i ʻole ke kāohi i kā lākou hana hormone. Hiki paha ke pono i ka ʻoki kino no nā ʻōpū nui a i ʻole nā ​​mea ʻaʻole pane i ka lāʻau lapaʻau.

E komo paha kāu hui lapaʻau i nā loea he nui, me nā endocrinologists, nā kauka ʻoki kino, a me nā oncologists paha. Ke kōkua nei ka nānā mau ʻana me nā ho'okolohua koko a me nā kiʻi e hopu i nā pilikia hou i ka wā mua ke maʻalahi lākou e mālama.

Pehea e mālama ai i ka MEN-1 ma ka home?

ʻO ka noho ʻana me ka MEN-1 e pono ai ka nānā mau ʻana i kou olakino, akā nui nā mea hiki iā ʻoe ke hana ma ka home e kākoʻo i kou ola maikaʻi a hana pono pū me kāu hui olakino.

E mālama i nā moʻolelo kikoʻī o kāu mau hōʻailona, ​​me ka wā i loaʻa ai, ko lākou koʻikoʻi, a me nā mea hoʻonāukiuki āpau. Kūleʻa kēia ʻike i kāu mau kauka e hoʻoponopono i kā lākou papa hana lapaʻau a hopu i nā pilikia hou i ka wā mua.

Inā loaʻa iā ʻoe nā pilikia e pili ana i ka calcium, e noho mau i ka wai maikaʻi ma o ka inu ʻana i ka wai nui i ka lā holoʻokoʻa. Kūleʻa kēia i ka pale ʻana i nā pōhaku kidney a kākoʻo i ka hana o kāu kidney. E pale i ka nui o nā mea hoʻohui calcium ke ʻole i kuhikuhi ʻia e kāu kauka.

No ka mālama ʻana i ke kō koko, e ʻai i nā ʻaina maʻamau, kaulike a lawe i nā papa glucose a i ʻole nā ​​mea ʻono inā pilikia ʻoe i nā hanana kō haʻahaʻa. E aʻo e ʻike i nā hōʻailona hoʻomaopopo mua o ka hypoglycemia i hiki iā ʻoe ke mālama koke.

E mālama i ka olakino ikaika o nā iwi ma o ka hoʻoikaika kino kaumaha maʻamau e like me ka ʻae ʻia, a e hōʻoia i ka lawa o ka lawe ʻana i ka huaora D. Eia naʻe, e kūkākūkā i nā mea hoʻohui me kāu hui olakino, ʻoiai ʻokoʻa paha kāu pono calcium mai ka lehulehu.

E hana i kahi kāleka ʻike lapaʻau e heluhelu i kou kūlana, nā lāʻau lapaʻau i kēia manawa, a me nā pilina pilikia. E mālama i kēia me ʻoe i nā manawa a pau, ʻoiai he ʻike koʻikoʻi ia no nā mea lawelawe olakino inā pono ʻoe i ka mālama pilikia.

Pehea ʻoe e hoʻomākaukau ai no kāu hālāwai me ke kauka?

ʻO ka hoʻomākaukau pono ʻana no kāu mau hālāwai e kōkua i ka hōʻoia ʻana e loaʻa iā ʻoe ka mea nui loa mai kāu manawa me kāu hui olakino a ʻaʻole e poina i nā nīnau a i ʻole nā ​​hopohopo nui.

E kākau i kāu mau hōʻailona a pau, me ka wā i hoʻomaka ai, pehea ka pinepine o ka loaʻa ʻana, a me nā mea e hoʻomaikaʻi ai a ʻoi aku ka maikaʻi ʻole paha. E hoʻokomo i nā hōʻailona i hiki ke manaʻo ʻole ʻia, ʻoiai hiki i ka MEN-1 ke hoʻokumu i nā pilikia like ʻole ma kou kino.

E lawe mai i ka papa inoa piha o nā lāʻau lapaʻau, nā mea hoʻohui, a me nā wikamina āu e lawe nei, me nā nui a me ka pinepine o kāu lawe ʻana. Hoʻopili kēia i nā lāʻau lapaʻau ma luna o ka pākaukau, no ka mea, hiki i kekahi ke launa pū me nā lāʻau MEN-1.

E ʻohi i kāu mōʻaukala lapaʻau ʻohana, me ka nānā nui ʻana i nā hoahānau i loaʻa i nā pilikia hormone, nā ʻōpū maʻamau ʻole, nā pōhaku kidney, a i ʻole nā ʻōpū ʻōpū. Hiki i kēia ʻike ke koʻikoʻi no ka ʻike a me ka hoʻolālā mālama.

E hoʻomākaukau i kahi papa inoa o nā nīnau e pili ana i kou kūlana, nā koho mālama, a me ka mea e manaʻo ai i ka wā e hiki mai ana. Mai hopohopo e nīnau i nā nīnau he nui - makemake kāu hui olakino e hoʻomaopopo piha ʻoe i kou kūlana.

E noʻonoʻo e lawe mai i kahi lālā ʻohana a hoaaloha hilinaʻi i kāu kūkā. Hiki iā lākou ke kōkua iā ʻoe e hoʻomanaʻo i ka ʻike koʻikoʻi a hāʻawi i ke kākoʻo manaʻo i ka wā e hiki mai ana nā kūkākūkā kaumaha e pili ana i kou olakino.

He aha ka mea nui e pili ana i ka MEN-1?

He kūlana genetic paʻakikī akā hiki ke hoʻokele ʻia ka MEN-1 e hoʻopilikia ana i nā gland hana hormone ma kou kino. ʻOiai e pono ai ka nānā a me ka mālama ʻana i ke ola holoʻokoʻa, nui nā kānaka me ka MEN-1 e ola ana i nā ola piha, hana me ka mālama lapaʻau kūpono.

He mea nui ka ʻike mua a me ka hahai mau ʻana i ka lāʻau lapaʻau no ka pale ʻana i nā pilikia koʻikoʻi. ʻO ke kī ka hana pili pono me kāu hui olakino e nānā i nā ʻōpū hou a hoʻokele pono i nā mea i loaʻa.

Inā loaʻa iā ʻoe ka MEN-1 a manaʻo paha ʻoe, e hoʻomanaʻo he ʻokoʻa kēia kūlana i kēlā me kēia kanaka. ʻAʻole like paha kāu ʻike me ka mea āu i heluhelu ai e pili ana i nā poʻe ʻē aʻe, a he mea maʻamau loa kēlā.

ʻO ka loaʻa ʻana o ka MEN-1 ʻo ia hoʻi e pono ai ʻoe i ka nānā lapaʻau ʻoi aku ma mua o ka hapanui o nā kānaka, akā ʻaʻole ia e hoʻomaopopo i kou ola. Me ka mālama a me ka nānā pono, hiki iā ʻoe ke hoʻokele i kou mau hōʻailona a mālama i kou maikaʻi o ke ola.

Nā nīnau pinepine e pili ana i ka MEN-1

Q.1: Ke hoʻoilina mau ʻia anei ka MEN-1 mai nā mākua?

Ma kahi o 90% o nā hihia MEN-1, ua hoʻoilina ʻia mai ka makua nona ke kūlana. Eia naʻe, ma kahi o 10% o nā hihia, he mau hoʻololi hou kēia, ʻo ia hoʻi ʻaʻohe makua o MEN-1. Inā loaʻa iā ʻoe ka MEN-1, aia ka manawa 50% o kēlā me kēia keiki nou e hoʻoilina ai i ka hoʻololi genetic.

Nīnau 2: Hiki i nā ʻōpū MEN-1 ke lilo i kanesa?

ʻO ka hapa nui o nā ʻōpū MEN-1 e noho maikaʻi mau ana i kou ola, akā aia kahi pilikia liʻiliʻi o ka hoʻololi ʻino, ʻoi aku hoʻi me nā ʻōpū pancreatic. ʻO ia ke kumu o ka pono o ka nānā mau ʻana a me ka mālama hoʻomau. ʻO ka ʻike mua ʻana i nā loli e hāʻawi i ka mālama koke inā pono.

Nīnau 3: Pehea pinepine ka pono iaʻu e nānā ʻia inā loaʻa iaʻu ka MEN-1?

ʻO ka hapa nui o nā kānaka me MEN-1 pono lākou i nā nānā makahiki a i ʻole nā ​​nānā ʻelua i ka makahiki e komo pū ana i nā hoʻokolohua koko a me nā haʻawina kiʻi. ʻO ka pinepine pololei e hilinaʻi ana i kāu mau hōʻailona o kēia manawa, nā kīʻaha i hoʻopilikia ʻia, a me ka paʻa o kou kūlana. E hana kāu hui olakino i kahi papa hana nānā pilikino no ʻoe.

Nīnau 4: Hiki i nā loli ʻai a i ʻole nā ​​ʻano ola ke kōkua i ka hoʻokele ʻana i ka MEN-1?

ʻOiai ʻaʻole hiki i nā loli ʻano ola ke hoʻōla i ka MEN-1 a i ʻole ke pale aku i ka hoʻomohala ʻana o nā ʻōpū, hiki iā lākou ke kōkua i ka hoʻokele ʻana i nā hōʻailona a me ke kākoʻo ʻana i kou olakino holoʻokoʻa. ʻO ka noho wai e kōkua i ka pale ʻana i nā pōhaku kidney, nā ʻaina maʻamau e kōkua i ka hoʻokele ʻana i ke kō koko, a me ka hoʻoikaika kūpono e kākoʻo i ke olakino o nā iwi. Eia naʻe, ʻo ka mālama lapaʻau ke ala nui.

Nīnau 5: Pono anei e hoʻokolohua ʻia kaʻu mau ʻohana no ka MEN-1?

Inā ua hōʻoia ʻoe i ka MEN-1, pono kāu mau hoahānau mua (mākua, kaikuaʻana, a me nā keiki) e kūkākūkā i ka hoʻokolohua genetic me kā lākou poʻe lawelawe olakino. ʻOiai inā ʻaʻohe o lākou hōʻailona, ​​ʻo ka ʻike ʻana i ko lākou kūlana genetic e hāʻawi i ka nānā kūpono a me ka hoʻoponopono mua inā pono. Hiki i ka ʻōlelo aʻo genetic ke kōkua i nā ʻohana e hana i nā hoʻoholo naʻauao e pili ana i ka hoʻokolohua.