He aha ka Sarcoma Pleomorphic Undifferentiated? Nā Hōʻailona, Nā Kumu, a me ka Lapaʻau

ʻO ka sarcoma pleomorphic undifferentiated (UPS) kahi ʻano o ka maʻi kanesa i hiki ke ulu ma nā wahi a pau o kou kino, ʻoiai ka mea maʻamau loa ma kou mau lima, nā wāwae, a i ʻole ke kumu. Loaʻa i kēia maʻi kanesa kona inoa no ka mea ʻokoʻa loa nā sela mai kekahi i kekahi ma lalo o ka microscope a ʻaʻole ʻike maopopo i kekahi ʻano o ka pūnaewele maʻamau.

Manaʻo ʻia ʻo UPS he maʻi kanesa kakaʻikahi, e pili ana i kahi 1 i 100,000 mau kānaka i kēlā me kēia makahiki. ʻOiai hiki ke manaʻo nui ka loaʻa ʻana o kēia ʻike, hiki i ka hoʻomaopopo ʻana i kāu mea e hana nei ke kōkua iā ʻoe e ʻike hou a hilinaʻi i kāu huakaʻi lapaʻau e hiki mai ana.

He aha ka sarcoma pleomorphic undifferentiated?

ʻO ka sarcoma pleomorphic undifferentiated kahi maʻi kanesa e ulu ana i loko o kou mau pūnaewele palupalu e like me nā ʻiʻo, ka momona, nā kīʻaha koko, a i ʻole nā ​​pūnaewele hoʻopili. ʻO ka huaʻōlelo "undifferentiated" ʻo ia hoʻi ʻaʻole like nā sela kanesa me kekahi ʻano o ka sela maʻamau, e hoʻopilikia ai i ka hoʻokaulike ʻana.

"Pleomorphic" e wehewehe ana i ke ʻano o kēia mau sela kanesa i nā ʻano a me nā nui like ʻole ke nānā ʻia ma lalo o ka microscope. ʻO kēia ʻokoʻa i ka helehelena kekahi o nā hiʻohiʻona nui a nā kauka e hoʻohana ai e ʻike i kēia ʻano sarcoma.

ʻO ka UPS maʻamau e ulu ana ma ke ʻano he nui paʻa, ʻeha ʻole e hiki ke piʻi mai kekahi mau kenimika a nui loa. ʻIke mua ka hapa nui o nā kānaka iā ia ma ke ʻano he ʻāpana e hoʻonui mālie ana i ka nui ma nā hebedoma a i ʻole nā ​​mahina.

Hoʻopili pinepine kēia maʻi kanesa i nā mākua ma waena o 50 a me 70 mau makahiki, ʻoiai hiki ke loaʻa i kēlā me kēia makahiki. Hoʻopili like ʻia nā kāne a me nā wahine, a hiki ke ulu i nā kānaka o nā ʻano lāhui āpau.

He aha nā hōʻailona o ka sarcoma pleomorphic undifferentiated?

ʻO ka hōʻailona mua maʻamau o ka UPS kahi ʻāpana a i ʻole ka nui ʻeha ʻole āu e hiki ai ke ʻike ma lalo o kou ʻili. ʻO kēia nui maʻamau e manaʻo ʻia paʻa a paʻakikī paha i ka pā a hiki ke ulu mālie i ka nui ma hope o ka manawa.

ʻAʻole ʻike ka nui o nā kānaka i ka ʻeha i ka wā mua, kahi i alakaʻi ai i ke kali ʻana i ka ʻimi ʻana i ka mālama lapaʻau. Eia nā hōʻailona āu e ʻike ai:

• Kahi ʻāpana paʻa, ulu a nui paha ma nā wahi a pau o kou kino
• ʻO ka pehu ʻana i ka wahi i hoʻopilikia ʻia
• ʻEha a ʻoluʻolu paha, ʻoi aku hoʻi ke ulu nui o ka tumor
• Ka palena ʻana o ka neʻe ʻana inā hoʻopilikia ka tumor i nā ʻiʻo a i ʻole nā ​​hui
• Numbness a tingling paha inā e kaomi ka tumor i nā aʻalo

ʻIke kekahi poʻe i nā hōʻailona kikoʻī hou aku ma muli o kahi e ulu ai ka tumor. Inā ulu ka UPS i kou wāwae a i ʻole lima, hiki iā ʻoe ke ʻike i ka nāwaliwali a i ʻole ka pilikia o ka neʻe ʻana i kēlā lālā maʻamau.

I nā hihia kakaʻikahi, ke ulu ka UPS i nā pūnaewele hohonu a i ʻole e hoʻopilikia i nā ʻōnaehana kūloko, hiki iā ʻoe ke ʻike i nā hōʻailona maʻamau e like me ka nalowale kaumaha wehe ʻole ʻia, ka luhi, a i ʻole ka mahana. Eia naʻe, he mea maʻamau ʻole kēia mau hōʻailona a maʻamau wale nō ke loaʻa me ka maʻi holomua loa.

He aha nā kumu o ka sarcoma pleomorphic undifferentiated?

ʻAʻole maopopo loa ke kumu pololei o ka sarcoma pleomorphic undifferentiated, akā manaʻo nā mea noiʻi e ulu ia ke hoʻololi nā sela maʻamau i loko o kou mau pūnaewele palupalu i nā hoʻololi genetic e hoʻokumu ai i ka ulu ʻana me ka manaʻo ʻole. Hana pinepine ʻia kēia mau hoʻololi ma ka manawa ma mua o ka hoʻoilina ʻia mai kou mau mākua.

Hiki i kekahi mau mea ke kōkua i ka hoʻomohala ʻana o ka UPS, ʻoiai ʻaʻole ʻo ka loaʻa ʻana o kēia mau pilikia e ʻōlelo ai e loaʻa nō ʻoe i ka maʻi kanesa:

• Ka lāʻau radiation mua no ka maʻi kanesa ʻē aʻe
• Ka hōʻike ʻana i kekahi mau kemika a i ʻole nā ​​toxins
• Ka mumū maʻi a i ʻole ka hōʻeha i nā pūnaewele palupalu
• Kekahi mau kūlana genetic hoʻoilina (kakaʻikahi loa)
• Nā hoʻololi cellular pili i ka makahiki ma hope o ka manawa

ʻO ka lāʻau radiation mua kekahi o nā mea pilikia i hoʻokumu ʻia. Inā loaʻa iā ʻoe ka lāʻau radiation no ka maʻi kanesa ʻē aʻe i nā makahiki i hala, aia kahi pilikia liʻiliʻi e hoʻomohala i ka UPS i ka wahi i mālama ʻia ma mua.

Eia naʻe, he mea nui e ʻike ʻaʻole loaʻa i ka hapa nui o nā kānaka me ka UPS nā pilikia maopopo. Manaʻo ʻia e ulu ka maʻi kanesa ma ka manawa ma nā kānaka olakino ʻē aʻe, hiki ke manaʻo huhū ke ho'āʻo nei ʻoe e hoʻomaopopo i ke kumu o kēia iā ʻoe.

I ka wā e ʻike ai i ke kauka no ka sarcoma pleomorphic undifferentiated?

Pono ʻoe e ʻike i kāu kauka inā ʻike ʻoe i kekahi ʻāpana hou a i ʻole ka nui e mau ana ma mua o kekahi mau hebedoma, ʻoi aku hoʻi inā e ulu ana a i ʻole e loli ana. ʻOiai ʻo ka hapa nui o nā ʻāpana he benign, ʻoi aku ka maikaʻi o ka loiloi ʻana iā lākou i ka wā mua.

Hoʻonohonoho i kahi kūkākūkā koke inā ʻike ʻoe i kēia mau hōʻailona hoʻomaopopo:

• Kahi ʻāpana nui ma mua o 2 iniha (5 kenimika) i ke anawaena
• Kekahi nui e ulu ana a i ʻole e loli ana i ka texture
• Kahi ʻāpana e manaʻo ʻia paʻakikī a i hoʻopaʻa ʻia paha ma kahi
• ʻEha, numbness, a i ʻole nāwaliwali i ka wahi i hoʻopilikia ʻia
• Kekahi ʻāpana e hoʻopilikia ana i ka neʻe maʻamau

Mai kali inā ke hoʻopilikia nei ka ʻāpana iā ʻoe a i ʻole e hoʻopilikia ana i kāu mau hana i kēlā me kēia lā. ʻO ka ʻike mua a me ka mālama ʻana e alakaʻi pinepine i nā hopena maikaʻi me nā sarcomas.

Inā loaʻa iā ʻoe ka mōʻaukala o ka lāʻau radiation, e makaʻala loa e pili ana i nā ʻāpana hou i nā wahi i mālama ʻia ma mua. ʻOiai he liʻiliʻi ka pilikia, makemake kāu kauka e loiloi hou aku i nā nui hou.

He aha nā pilikia no ka sarcoma pleomorphic undifferentiated?

ʻOiai hiki ke mālama maikaʻi ʻia ka nui o nā kānaka me ka UPS, ke kōkua nei ka hoʻomaopopo ʻana i nā pilikia hiki ke kōkua iā ʻoe e ʻike i nā mea e nānā ai a i ka wā e hoʻokaʻaʻike ai i kāu hui mālama ola. ʻO ka manaʻo nui me ka UPS ʻo kona hiki ke pālahalaha i nā ʻāpana ʻē aʻe o kou kino inā ʻaʻole mālama koke ʻia.

ʻO nā pilikia koʻikoʻi loa e komo pū ana:

• Metastasis (spread) i nā māmā, ate, a i ʻole nā ​​ʻōnaehana ʻē aʻe
• Local recurrence ma hope o ka mālama ʻana
• Ka hōʻino ʻana i nā aʻalo inā e kaomi ka tumor i nā aʻalo nui
• Ka nalowale o ka hana i nā ʻiʻo a i ʻole nā ​​hui i hoʻopilikia ʻia
• Nā pilikia mai ka ʻoki a i ʻole nā ​​mālama ʻē aʻe

Loaʻa i ka UPS kahi ʻano e pālahalaha ai ma o ke kahe koko, me nā māmā kahi wahi maʻamau o ka metastasis. ʻO ia ke kumu e kauoha ai kāu kauka i ka hoʻolālā umauma ma ke ʻano he ʻāpana o kāu loiloi mua a me ka mālama hope.

Hiki ke hana ʻia ka local recurrence, kahi e hoʻi hou mai ai ka maʻi kanesa i ka wahi hoʻokahi ma hope o ka mālama ʻana, inā koe nā sela kanesa microscopic ma hope o ka ʻoki ʻana. ʻO ia ke kumu e nui ai ka wehe ʻana i ka ʻoki ʻana me nā palena maopopo.

I nā hihia kakaʻikahi, hiki i nā tumor nui ke hoʻokumu i nā pilikia nui ma mua o ka mālama ʻana. Hiki paha kēia ke komo pū me ka hoʻokaumaha ʻana i nā kīʻaha koko nui, nā aʻalo, a i ʻole nā ​​ʻōnaehana, ma muli o kahi o ka tumor.

Pehea ka hōʻoia ʻana o ka sarcoma pleomorphic undifferentiated?

Pono ka hōʻoia ʻana o ka UPS i kekahi mau hana e hōʻoia i ke ʻano o ka maʻi kanesa a hoʻoholo i kahi āna i pālahalaha ai. E hoʻomaka kāu kauka me kahi hoʻokolokolo kino a laila e kauoha i nā ho'āʻo kiko'ī e loaʻa ai kahi kiʻi piha.

ʻO ke kaʻina hana hōʻoia e komo pū ana:

1. Hoʻokolokolo kino a me ka mōʻaukala lapaʻau
2. Nā haʻawina imaging (MRI, CT scan, a i ʻole ultrasound)
3. Biopsy e nānā i ka pūnaewele ma lalo o ka microscope
4. Nā ho'āʻo hou aku e nānā i ka pālahalaha (staging)
5. Ka ho'āʻo genetic o ka tumor (i kekahi mau hihia)

ʻO ka biopsy ka hana nui loa no ka mea ʻo ia wale nō ke ala e hōʻoia ai i ka UPS. E wehe kāu kauka i kahi ʻāpana liʻiliʻi o ka tumor me kahi nila a i ʻole ma o kahi ʻoki liʻiliʻi.

Kōkua nā haʻawina imaging e hoʻoholo i ka nui a me kahi o ka tumor, a me kona pilina me nā mea kokoke e like me nā kīʻaha koko, nā aʻalo, a me nā iwi. He mea nui kēia ʻike no ka hoʻolālā ʻana i kāu mālama.

Kōkua nā ho'āʻo Staging, e komo pū paha me nā X-rays umauma a i ʻole nā ​​CT scan, e hoʻoholo inā ua pālahalaha ka maʻi kanesa i nā ʻāpana ʻē aʻe o kou kino. Hoʻopili nui kēia ʻike i kāu mau koho mālama a me ka prognosis.

He aha ka mālama ʻana no ka sarcoma pleomorphic undifferentiated?

ʻO ka mālama ʻana no ka UPS maʻamau e komo pū ana me ka hui ʻana o nā ala i hoʻopilikino ʻia i kāu kūlana kikoʻī. ʻO ka ʻoki ʻana maʻamau ka mālama nui, pinepine ʻia me ka lāʻau radiation a i ʻole chemotherapy e hāʻawi iā ʻoe i ka manawa maikaʻi loa o ka ho'ōla.

Hiki i kāu hoʻolālā mālama ke komo pū me:

• ʻOki e wehe i ka tumor me nā palena maopopo
• Lāʻau radiation ma mua a ma hope paha o ka ʻoki ʻana
• Chemotherapy, ʻoi aku hoʻi no nā tumor nui a i ʻole kiʻekiʻe
• Targeted therapy a i ʻole immunotherapy (i kekahi mau hihia)
• Hoʻōla a me ka mālama kākoʻo

Pahuhopu o ka ʻoki ʻana e wehe i ka tumor holoʻokoʻa me kahi palena o nā pūnaewele olakino a puni ia. I kekahi manawa pono kēia e wehe i nā ʻiʻo i hoʻopilikia ʻia, a i nā hihia kakaʻikahi, hiki ke pono ka amputation, ʻoiai hiki ke hana ʻia ka ʻoki ʻana i ka lālā i ka hapa nui o nā hihia.

Hoʻohana ka lāʻau radiation i nā kukui kiʻekiʻe e pepehi i nā sela kanesa a pinepine ʻia ma mua o ka ʻoki ʻana e hoʻemi i ka tumor a ma hope paha o ka ʻoki ʻana e luku i nā sela kanesa i koe. ʻO ka manawa e hilinaʻi ana i kāu kūlana kikoʻī.

Hiki ke kuhikuhi ʻia ka Chemotherapy inā nui kāu tumor, kiʻekiʻe, a i ʻole inā pilikia e pili ana i ka pālahalaha microscopic. ʻOiai ʻaʻole pane pinepine ka UPS i ka chemotherapy, hiki ke kōkua i kekahi mau kūlana.

E hana pū kāu hui mālama e hana i kahi hoʻolālā e hāʻawi iā ʻoe i ka manawa maikaʻi loa o ka ho'ōla ʻana ʻoiai e mālama ana i ka hana nui i ka wahi i hoʻopilikia ʻia.

Pehea e mālama ai i ka sarcoma pleomorphic undifferentiated ma ka home?

ʻO ka mālama ʻana i ka UPS ma ka home e komo pū ana me ka mālama ʻana iā ʻoe iho i ka wā mālama a me ka hoʻōla ʻana ʻoiai e makaʻala ana i nā loli e pono ai ka nānā lapaʻau. He mau ʻāpana nui kāu hōʻoluʻolu a me kou olakino i kāu hoʻolālā mālama holoʻokoʻa.

Eia nā ala e kākoʻo ai i kou olakino i ka wā mālama:

• E hahai pono i kāu papa lāʻau e like me ka kuhikuhi ʻana
• E mālama i nā wahi ʻoki maʻemaʻe a maloʻo e like me ka kuhikuhi ʻana
• E mālama i ka meaʻai maikaʻi e kākoʻo i ka ho'ōla
• E noho ikaika e like me kāu kauka e kuhikuhi ai
• E nānā i nā hōʻailona o ka maʻi a i ʻole nā ​​pilikia

E hoʻolohe i nā loli i kāu wahi ʻoki, e like me ka hoʻonui ʻana o ka ʻulaʻula, ka pehu, ka mahana, a i ʻole ka hoʻokahe. Hiki i kēia ke hōʻailona o ka maʻi e pono ai ka nānā lapaʻau koke.

Hiki i ka hoʻoikaika mālie a me ka lāʻau kino, e like me ka kuhikuhi ʻana mai kāu hui mālama ola, ke kōkua i ka mālama ʻana i ka ikaika a me ka oluolu i ka wā hoʻōla. Mai hoʻoikaika nui iā ʻoe iho, akā ʻo ka noho ʻana i ka hana maʻamau e kōkua pinepine i ka ho'ōla.

ʻO ka mālama ʻana i nā hopena mai ka chemotherapy a i ʻole radiation paha e komo pū paha me ka ʻai ʻana i nā meaʻai liʻiliʻi, pinepine inā ʻike ʻoe i ka nausea, e noho hydrated, a loaʻa ka nui o ka hoʻomaha ke luhi ʻoe.

Pehea ʻoe e hoʻomākaukau ai no kāu kūkākūkā kauka?

ʻO ka hoʻomākaukau ʻana no kāu kūkākūkā e kōkua i ka hōʻoia ʻana e loaʻa iā ʻoe ka hapa nui o kāu manawa me kāu hui mālama ola. Hiki i ka loaʻa ʻana o kāu mau nīnau a me nā manaʻo i hoʻonohonoho ʻia ke kōkua i ka hoʻemi ʻana i ka hopohopo a hōʻoia ʻaʻole poina kekahi mea nui.

Ma mua o kāu kūkākūkā, e hōʻiliʻili i kēia ʻike:

• Kahi papa inoa o kāu mau lāʻau lapaʻau a me nā mea hoʻohui āpau
• Kāu mōʻaukala lapaʻau piha, me nā maʻi kanesa ma mua
• Mōʻaukala ʻohana o ka maʻi kanesa a i ʻole nā ​​kūlana genetic
• Kekahi mau haʻawina imaging a i ʻole nā ​​hopuna o nā ho'āʻo mai nā kauka ʻē aʻe
• ʻIke ʻinikua a me nā palapala kuhikuhi inā pono

E kākau i kāu mau nīnau ma mua o ka manawa i ʻole ʻoe e poina iā lākou i ka wā kūkākūkā. Hiki i nā nīnau maʻamau ke komo pū me ka nīnau ʻana e pili ana i nā koho mālama, nā hopena hiki, ka prognosis, a pehea ka hoʻopilikia ʻana o ka mālama i kou ola i kēlā me kēia lā.

E noʻonoʻo e lawe mai i kahi hoa aloha a i ʻole ʻohana hilinaʻi e kōkua iā ʻoe e hoʻomanaʻo i ka ʻike i kūkākūkā ʻia i ka wā kūkākūkā. Hiki nō hoʻi ke kōkua ka loaʻa ʻana o ke kākoʻo manaʻo i ka wā e hana nei me ka ʻike maʻi kanesa.

Mai kānalua e noi i kāu kauka e wehewehe i kekahi mea āu i ʻike ʻole ai. He mea nui ia e ʻoluʻolu ʻoe i kāu hoʻolālā mālama a ʻike i nā mea e manaʻo ai.

He aha ka lawe nui e pili ana i ka sarcoma pleomorphic undifferentiated?

ʻO ka sarcoma pleomorphic undifferentiated kahi maʻi kanesa kakaʻikahi akā hiki ke mālama ʻia e pono ai ka nānā lapaʻau koke a me ka mālama piha. ʻOiai hiki ke manaʻo nui ka loaʻa ʻana o kēia ʻike, hiki ke mālama maikaʻi ʻia ka nui o nā kānaka me ka UPS, ʻoi aku hoʻi ke hopu koke ʻia ka maʻi kanesa.

ʻO ka mea nui loa e hoʻomanaʻo ai ʻo ka ʻike mua a me ka mālama ʻana e kahi hui sarcoma akamai e hoʻomaikaʻi nui i nā hopena. Inā ʻike ʻoe i kekahi ʻāpana mau, ulu, mai kali e loiloi ʻia.

ʻOkoʻa ka kūlana o kēlā me kēia kanaka, a e hoʻopilikino ʻia kāu hoʻolālā mālama i kāu mau pono. ʻO ka hana pili me kāu hui mālama ola, ka nīnau ʻana i nā nīnau, a me ka noho ʻike e pili ana i kou kūlana e kōkua iā ʻoe e ʻike hou aku i ka mana o kāu huakaʻi.

ʻOiai paʻakikī paha ke ala i mua, e hoʻomanaʻo e hoʻomau ana nā holomua i ka mālama sarcoma e hoʻomaikaʻi i nā hopena no nā kānaka me ka UPS. Aia kāu hui lapaʻau e kākoʻo iā ʻoe i kēlā me kēia ʻanuʻu o ke ala.

Nā nīnau i nīnau pinepine ʻia e pili ana i ka sarcoma pleomorphic undifferentiated

Q.1 He mea make mau anei ka sarcoma pleomorphic undifferentiated?

ʻAʻole, ʻaʻole make mau ka UPS. Hiki ke ho'ōla ʻia ka nui o nā kānaka me ka UPS, ʻoi aku hoʻi ke ʻike koke ʻia ka maʻi kanesa a ʻaʻole i pālahalaha i nā ʻāpana ʻē aʻe o ke kino. ʻO ka prognosis e hilinaʻi ana i nā mea e like me ka nui a me kahi o ka tumor, inā ua pālahalaha, a pehea ka pane maikaʻi i ka mālama. Me ka mālama kūpono mai kahi hui sarcoma akamai, hele nā ​​maʻi he nui i ka ola maʻamau, olakino.

Q.2 Hiki i ka sarcoma pleomorphic undifferentiated ke hoʻi mai ma hope o ka mālama ʻana?

ʻAe, hiki i ka UPS ke hoʻi hou mai ma hope o ka mālama ʻana, ʻoiai ʻaʻole kēia e hana i nā kānaka āpau. ʻO ka local recurrence i ka wahi hoʻokahi e hana ana ma kahi o 10-20% o nā hihia, ʻoiai ʻoi aku ka liʻiliʻi o ka recurrence mamao (metastasis). ʻO ia ke kumu e nui ai nā kūkākūkā hope a me nā haʻawina imaging. ʻO ka ʻike mua ʻana o kekahi recurrence e ʻae i ka mālama koke, hiki ke maikaʻi loa.

Q.3 Pehea ka wikiwiki o ka ulu ʻana o ka sarcoma pleomorphic undifferentiated?

ʻO ka UPS maʻamau e ulu mālie ana ma nā hebedoma a i nā mahina paha, ʻoiai hiki ke loli ke wikiwiki o ka ulu ʻana mai ke kanaka i ke kanaka. Hiki i kekahi mau tumor ke ulu wikiwiki aku, ʻoiai kekahi e ulu mālie ana ma kahi manawa lōʻihi. Hiki i ka papa o ka tumor, kahi e wehewehe ai i ke ʻano hoʻouluulu o nā sela kanesa ma lalo o ka microscope, ke hāʻawi i nā kauka i ka manaʻo o ka wikiwiki o ka ulu ʻana a me ka pālahalaha.

Q.4 Pono anei iaʻu ka amputation inā loaʻa iaʻu ka sarcoma pleomorphic undifferentiated?

Kakaʻikahi wale nō ka amputation no ka UPS. I ka hapa nui o nā hihia, hiki i ka ʻoki ʻana i ka lālā ke wehe maikaʻi i ka tumor ʻoiai e mālama ana i ka lima a i ʻole ka wāwae i hoʻopilikia ʻia. ʻO nā ʻenehana ʻoki hou, i hui pū ʻia me ka lāʻau radiation, e ʻae i nā kauka e hoʻokō i ka mālama kanesa maikaʻi ʻoiai e mālama ana i ka hana. Ua manaʻo ʻia ka Amputation i nā hihia kakaʻikahi wale nō kahi e pono loa ai e wehe loa i ka maʻi kanesa.

Q.5 He mea hoʻoilina anei ka sarcoma pleomorphic undifferentiated?

Kakaʻikahi loa ka UPS he mea hoʻoilina. ʻOi aku ka liʻiliʻi o 5% o nā hihia e pili ana i nā kūlana genetic hoʻoilina e like me ka Li-Fraumeni syndrome. ʻAʻohe mōʻaukala ʻohana o ka maʻi a ʻaʻohe predisposition genetic i ka hapa nui o nā kānaka me ka UPS. Maʻamau e ulu ka maʻi kanesa ma muli o nā hoʻololi genetic kūpono ʻole e hana ana i ke ola o ke kanaka ma mua o ka hoʻoili ʻia mai nā mākua.