He aha ka Abacavir a me Lamivudine: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Abacavir a me lamivudine he lāʻau lapaʻau HIV hui e kōkua ana i ka mālama ʻana i ka maʻi i loko o kou kino. Aia i loko o kēia lāʻau lapaʻau i kauoha ʻia ʻelua mau lāʻau antiretroviral ikaika e hana pū ana e hoʻolohi i ka hiki o ka HIV ke hoʻonui a laha i loko o kāu ʻōnaehana.

Hiki paha iā ʻoe ke ʻike i kēia lāʻau lapaʻau ma nā inoa inoa e like me Epzicom a i ʻole Kivexa. He ʻāpana ia o kahi hoʻolālā lapaʻau e hiki ke kōkua iā ʻoe e ola i ke ola olakino a lōʻihi me ka HIV ke lawe ʻia me ka hoʻomau e like me ke kauoha ʻia e kāu mea mālama ola.

He aha ka Abacavir a me Lamivudine?

ʻO Abacavir a me lamivudine he papa hui i hoʻopaʻa ʻia i loaʻa i ʻelua mau lāʻau HIV like ʻole i hoʻokahi pila. No ka papa o nā lāʻau i kapa ʻia ʻo nucleoside reverse transcriptase inhibitors nā mea ʻelua, e hana ana ma ka pale ʻana i ka HIV mai ka hana hou ʻana iā ia iho i loko o kāu mau cell.

ʻO kēia hui ʻana e maʻalahi iā ʻoe ke lawe i kāu lapaʻau HIV no ka mea loaʻa iā ʻoe ʻelua mau lāʻau i hoʻokahi mahele. Hele mai ka lāʻau lapaʻau ma ke ʻano he papa e ale ʻoe i ka holoʻokoʻa, a ua hoʻolālā ʻia e lilo i ʻāpana o kahi hoʻolālā lapaʻau HIV piha me nā lāʻau antiretroviral ʻē aʻe.

E kauoha kāu kauka i kēia lāʻau lapaʻau ma ke ʻano he ʻāpana o ka mea i kapa ʻia ʻo highly active antiretroviral therapy a i ʻole HAART. Hoʻohana kēia ʻano hana i nā lāʻau HIV he nui e hana i kahi pale ikaika i ka maʻi i loko o kou kino.

No ke aha e hoʻohana ʻia ai ka Abacavir a me Lamivudine?

Hoʻohana ʻia kēia lāʻau lapaʻau no ka mālama ʻana i ka maʻi HIV-1 i nā pākeke a me nā keiki e kaupaona ana ma ka liʻiliʻi he 25 kilokani (ma kahi o 55 paona). Hana ia ma ke ʻano he ʻāpana o kahi lapaʻau hui e kōkua i ka hōʻemi ʻana i ka nui o ka HIV i loko o kou koko i nā pae hiki ʻole ke ʻike ʻia.

ʻO ka pahuhopu nui e kōkua i kāu ʻōnaehana pale e ola hou a noho ikaika i ka wā e pale ai i ka HIV mai ka holomua ʻana i ka AIDS. Ke hoʻohana pololei ʻia me nā lāʻau HIV ʻē aʻe, hiki i kēia hui ke kōkua iā ʻoe e mālama i ke ola maʻamau a pale i ka hoʻouna ʻana i ka maʻi i nā poʻe ʻē aʻe.

Hiki i kāu mea mālama ola ke ʻōlelo aku i kēia hui ʻana inā e hoʻomaka ana ʻoe i ka lāʻau lapaʻau HIV no ka manawa mua a i ʻole inā pono ʻoe e hoʻololi mai kahi ʻano lapaʻau ʻē aʻe. He mea nui e hoʻomaopopo i kēia lāʻau lapaʻau e mālama ana i ka HIV akā ʻaʻole ia e hoʻōla loa.

Pehea e Hana ai ʻo Abacavir a me Lamivudine?

Hana kēia hui ʻana i ka lāʻau lapaʻau ma ka hoʻopilikia ʻana i ka hiki o ka HIV ke hana hou i loko o kāu mau keʻena. Hoʻopaʻa ʻo Abacavir a me lamivudine i kahi enzyme i kapa ʻia ʻo reverse transcriptase, pono ka HIV e kope i kāna mea genetic a hana i nā ʻāpana virus hou.

E noʻonoʻo e like me ka waiho ʻana i kahi wili i loko o nā mea hana o ka mīkini kope o ka HIV. Ke hoʻāʻo ka virus e hoʻonui, pale kēia mau lāʻau lapaʻau iā ia mai ka hoʻopau pono ʻana i ke kaʻina hana. Kōkua kēia i ka hōʻemi ʻana i ka ukana viral i loko o kou koko i ka manawa.

Manaʻo ʻia ka lāʻau lapaʻau he mea ikaika loa ke hui pū ʻia me nā lāʻau HIV ʻē aʻe. ʻOiai he mea maikaʻi, hana maikaʻi loa ia ma ke ʻano he ʻāpana o kahi ʻano lāʻau lapaʻau ʻekolu lāʻau ma mua o ka hoʻohana ʻana wale nō, ʻo ia ke kumu e kuhikuhi ai kāu kauka i nā lāʻau HIV hou aʻe me ia.

Pehea wau e lawe ai iā Abacavir a me Lamivudine?

Pono ʻoe e lawe i kēia lāʻau lapaʻau e like me ke kauoha a kāu kauka, maʻamau i hoʻokahi manawa i ka lā me ka ʻole o ka meaʻai. Hiki ke lawe ʻia ka papa me ka wai, ka waiū, a i ʻole ka wai, a ʻaʻole pono ʻoe e hopohopo e pili ana i ka manawa me nā meaʻai no ka mea ʻaʻole pili nui ka meaʻai i ke ʻano o kou kino e komo ai i ka lāʻau lapaʻau.

E hoʻāʻo e lawe i kāu mahele i ka manawa like i kēlā me kēia lā e kōkua i ka mālama ʻana i nā pae paʻa o ka lāʻau lapaʻau i kāu ʻōnaehana. Hiki iā ʻoe ke hoʻonohonoho i kahi alarm i kēlā me kēia lā a i ʻole e hoʻohana i kahi mea hoʻonohonoho pila e kōkua iā ʻoe e hoʻomanaʻo, no ka mea, ʻo ka nalo ʻana i nā mahele hiki ke ʻae i ka HIV e lilo i mea kūʻē i ka lāʻau lapaʻau.

E ale i ka papa holoʻokoʻa ma mua o ka ʻoki ʻana, ka nau ʻana, a i ʻole ka wāwahi ʻana. Inā pilikia ʻoe i ka ale ʻana i nā pila, e kamaʻilio me kāu kauka lapaʻau e pili ana i nā ʻenehana e kōkua ai, akā mai hoʻololi i ke ʻano o ka papa me ka ʻole o ke alakaʻi.

Ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau, e hoʻāʻo kāu kauka iā ʻoe no kahi hōʻailona genetic i kapa ʻia ʻo HLA-B*5701. He mea nui kēia hoʻāʻo ʻana no ka mea ʻoi aku ka pilikia o ka poʻe me kēia ʻano genetic i nā hopena maʻi maʻi koʻikoʻi i ka abacavir.

Pehea ka lōʻihi e lawe ai au i ka Abacavir a me Lamivudine?

Pono ʻoe e lawe i kēia lāʻau lapaʻau no ke koena o kou ola ma ke ʻano he ʻāpana o kāu mālama HIV e hoʻomau nei. He hana lōʻihi ka mālama ʻana i ka HIV e koi ana i ka lāʻau lapaʻau i kēlā me kēia lā e mālama i ka maʻi i kāohi ʻia a me ke olakino o kāu ʻōnaehana pale.

Hoʻomaka ka hapa nui o nā kānaka e ʻike i nā hoʻomaikaʻi ʻana i kā lākou ukana viral i loko o 2-8 mau pule o ka hoʻomaka ʻana i ka lāʻau lapaʻau, me nā hōʻemi nui e hana maʻamau i loko o 3-6 mau mahina. E nānā kāu kauka i kāu holomua ma o nā hoʻāʻo koko maʻamau e hōʻoia i ka hana pono ʻana o ka lāʻau lapaʻau.

Mai hooki i ka lawe ʻana i kēia lāʻau lapaʻau me ka ʻole e kamaʻilio mua me kāu mea mālama ola, ʻoiai inā maikaʻi ʻoe. ʻO ka hooki ʻana i ka mālama ʻana i ka HIV hiki ke hoʻonui wikiwiki i ka maʻi a hiki ke kūkulu i ke kūpaʻa i nā lāʻau lapaʻau, e paʻakikī ai ka mālama ʻana i ka wā e hiki mai ana.

He aha nā hopena ʻaoʻao o Abacavir a me Lamivudine?

Hoʻomanawanui ka hapa nui o nā kānaka i kēia lāʻau lapaʻau, akā e like me nā lāʻau lapaʻau a pau, hiki iā ia ke hana i nā hopena ʻaoʻao. ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a hoʻomaikaʻi pinepine i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau i nā pule mua.

Eia nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike:

• ʻEha ke poʻo a me ka luhi
• Nausea a me ka ʻōpū
• Pāpaʻa a i ʻole nā ​​pahu wai
• He pilikia i ka hiamoe a i ʻole nā ​​moeʻuhane maopopo
• ʻO ka ʻūlū a i ʻole ke poʻo
• Ihu paʻa a i ʻole ka ihu

ʻO kēia mau hopena ʻaoʻao i kēlā me kēia lā e lilo pinepine i mea liʻiliʻi e like me ka maʻa ʻana o kou kino i ka lāʻau lapaʻau. Inā mau lākou a i ʻole ke keakea i kāu mau hana i kēlā me kēia lā, hiki i kāu mea mālama ola ke hōʻike i nā ala e mālama ai iā lākou.

Akā, aia kekahi mau hopena ʻino nui e pono ai ke kōkua olakino koke, ʻoiai ʻaʻole lākou i maʻamau:

• Nā hopena maʻi maʻi koʻikoʻi (hypersensitivity syndrome)
• Lactic acidosis (ka hōʻiliʻili ʻana o ka waikawa lactic i loko o ke koko)
• Nā pilikia ate koʻikoʻi
• Ka hoʻonui ʻana o ka hepatitis B (inā loaʻa iā ʻoe kēia maʻi hui pū)

ʻO ka hopena hypersensitivity i ka abacavir ka hopena ʻino nui loa. Hiki iā ia ke hoʻoulu i ke kuni, ka ʻōpala, ka luhi nui, ka ʻeha o ka ʻōpū, a me nā hōʻailona e like me ka maʻi flu. Inā loaʻa iā ʻoe kēia mau hōʻailona, ​​ʻoiai i nā pule ʻeono mua o ka mālama ʻana, e kelepona koke i kāu kauka a mai lawe hou i ka lāʻau.

ʻO wai ka mea ʻaʻole pono e lawe iā Abacavir a me Lamivudine?

ʻAʻole pono ʻoe e lawe i kēia lāʻau inā he maʻi ʻoe i ka abacavir, lamivudine, a i ʻole nā ​​mea ʻē aʻe i loko o ka papa. Eia kekahi, inā e hōʻike ana ʻoe i ka HLA-B*5701 genetic marker, e koho kāu kauka i kahi lāʻau lapaʻau HIV ʻē aʻe e pale aku i ka pilikia o nā hopena maʻi maʻi koʻikoʻi.

Pono paha ka poʻe me ka maʻi ate mai ka maʻi maʻi a i ʻole nā ​​lāʻau ʻē aʻe. E nānā kāu mea mālama ola i kāu hana ate ma mua o ka hoʻomaka ʻana i ka mālama ʻana a nānā mau i ka wā e lawe ana ʻoe i ka lāʻau.

Inā he pilikia kou puʻupaʻa, pono paha i kāu kauka e hoʻoponopono i kāu mahele a i ʻole e noʻonoʻo i nā lāʻau lapaʻau ʻē aʻe. Hoʻoponopono ʻia nā mea ʻelua o kēia lāʻau lapaʻau ma o kou mau puʻupaʻa, no laila hiki i ka hana puʻupaʻa ke hoʻopilikia i ke ʻano o ka lāʻau i loko o kou kino.

Hiki i nā wahine hāpai ke lawe i kēia lāʻau, akā pono ka nānā ʻana. Inā ʻoe e hoʻolālā nei e hāpai a i ʻole e ʻike ʻoe e hāpai ana i ka wā e lawe ana i kēia lāʻau, e kūkākūkā i nā pilikia a me nā pōmaikaʻi me kāu mea mālama ola.

Nā inoa inoa o Abacavir a me Lamivudine

ʻO nā inoa inoa maʻamau no kēia hui ʻana o ka lāʻau lapaʻau ʻo Epzicom ma ʻAmelika Hui Pū ʻIa a me Kivexa ma nā ʻāina ʻē aʻe. Loaʻa i nā mea ʻelua nā mea hana like: 600 mg o abacavir a me 300 mg o lamivudine no ka papa.

Hiki ke loaʻa nā mana generic ma kekahi mau wahi, a he mau mea hana like nō naʻe he mau mea hana ʻole a i ʻole ke ʻano like ʻole. Hiki i kāu kauka lapaʻau ke kōkua iā ʻoe e ʻike inā e loaʻa ana iā ʻoe ka inoa inoa a i ʻole ka mana generic.

E nānā mau me kāu mea mālama ola ma mua o ka hoʻololi ʻana ma waena o nā inoa inoa a me nā mana generic, no ka mea, makemake lākou e hōʻoia i ka kūlike i kāu hana lapaʻau.

Nā Koho ʻē aʻe no Abacavir a me Lamivudine

Nui nā hui ʻana o nā lāʻau lapaʻau HIV ʻē aʻe e hiki ke lilo i mau koho ʻē aʻe inā ʻaʻole kūpono kēia hui ʻana iā ʻoe. Hiki i kāu kauka ke noʻonoʻo i ka emtricitabine a me tenofovir (Truvada), emtricitabine a me tenofovir alafenamide (Descovy), a i ʻole nā hui ʻana o nā mea pale transcriptase reverse nucleoside.

No ka poʻe hiki ʻole ke lawe i ka abacavir ma muli o ka HLA-B*5701 positivity, ʻo nā koho ʻē aʻe e pili ana i nā hui tenofovir. Hana like kēia mau mea ma ka pale ʻana i ka hana hou ʻana o ka HIV akā hoʻohana i nā ʻano hana like ʻole a loaʻa nā ʻano hopena ʻaoʻao like ʻole.

E noʻonoʻo kāu mea mālama ola i nā mea e like me kāu hana ʻana o nā puʻupaʻa, ke olakino o nā iwi, nā maʻi olakino ʻē aʻe, a me nā pilina lāʻau lapaʻau e hiki ke koho i ke koho maikaʻi loa no kāu kūlana.

ʻOi aku ka maikaʻi o Abacavir a me Lamivudine ma mua o Tenofovir a me Emtricitabine?

He mau lāʻau lapaʻau HIV maikaʻi loa nā hui ʻelua, akā ʻaʻole i

Hiki ke makemake ʻia ʻo Abacavir a me lamivudine inā he pilikia kou puʻupaʻa a i ʻole nā pilikia o ka iwi, no ka mea, hiki i ka tenofovir ke hoʻopilikia i kēia mau wahi. Eia naʻe, hiki ke koho ʻia nā hui tenofovir inā he maikaʻi kāu hōʻike no HLA-B*5701 a i ʻole he mau maʻi ate.

E noʻonoʻo kāu kauka i kāu moʻolelo olakino piha, nā hopena o ka hale hana, a me nā makemake pilikino i ka wā e hoʻoholo ai i ka hui ʻana e hana maikaʻi loa iā ʻoe. Ua hōʻoia ʻia nā koho ʻelua i nā moʻolelo maikaʻi i nā haʻawina lapaʻau a me ka hoʻohana ʻana i ka honua maoli.

Nā Nīnau i Nīnau pinepine ʻia e pili ana iā Abacavir a me Lamivudine

He palekana anei ʻo Abacavir a me Lamivudine no ka poʻe me ka Hepatitis B?

Hiki ke hoʻohana ʻia kēia lāʻau lapaʻau i ka poʻe me ka hepatitis B, akā pono ia i ka nānā pono ʻana. He hana ʻo Lamivudine e kūʻē i ka maʻi hepatitis B, no laila inā loaʻa iā ʻoe ka HIV a me ka hepatitis B, hiki i ka hooki ʻana i kēia lāʻau lapaʻau ke hoʻoulu nui i kāu hepatitis B.

E nānā pono kāu kauka i kāu hana ate a hiki ke kauoha i ka lāʻau lapaʻau hepatitis B hou inā pono. Mai hooki i ka lawe ʻana i kēia lāʻau lapaʻau me ka nānā ʻole ʻana i ka lāʻau lapaʻau inā loaʻa iā ʻoe ka maʻi hepatitis B.

He aha kaʻu e hana ai inā lawe hewa au i ka nui o Abacavir a me Lamivudine?

Inā lawe hewa ʻoe i ka nui ma mua o kāu mahele i kuhikuhi ʻia, e hoʻokaʻaʻike koke i kāu mea mālama ola a i ʻole ke kikowaena hoʻomalu ʻawa. ʻOiai ʻaʻole maʻamau nā hōʻailona overdose koʻikoʻi me kēia lāʻau lapaʻau, hiki i ka lawe ʻana i ka nui ke hoʻonui i kou pilikia o nā hopena ʻaoʻao.

Mai ho'āʻo e uku no ka mahele keu ma ka lele ʻana i kāu mahele i hoʻonohonoho ʻia. Akā, e hoʻomau me kāu papa hana maʻamau ke ʻole e ʻōlelo kāu kauka.

He aha kaʻu e hana ai inā e hala au i kahi mahele o Abacavir a me Lamivudine?

Inā hala ʻoe i kahi mahele, e lawe koke iā ia ke hoʻomanaʻo ʻoe, ke ʻole kokoke ka manawa no kāu mahele i hoʻonohonoho ʻia. I kēlā hihia, e lele i ka mahele i hala a lawe i kāu mahele aʻe i ka manawa maʻamau.

Mai lawe i nā lāʻau ʻelua i ka manawa hoʻokahi e pani ai i ka lāʻau i hala. Inā poina pinepine ʻoe i nā lāʻau, e kamaʻilio me kāu mea mālama ola e pili ana i nā hoʻolālā e kōkua iā ʻoe e hoʻomanaʻo, e like me ka hoʻonohonoho ʻana i nā ʻōhua kelepona a i ʻole ka hoʻohana ʻana i nā mea hoʻonohonoho pila.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Abacavir a me Lamivudine?

ʻAʻole pono ʻoe e hooki i ka lawe ʻana i kēia lāʻau me ka ʻole e kūkākūkā mua me kāu mea mālama ola. He ola mau ka mālama ʻana i ka HIV, a ʻo ka hooki ʻana i ka lāʻau lapaʻau hiki ke hoʻonui wikiwiki i ka maʻi a hiki ke hoʻomohala i ke kūpaʻa.

Hiki i kāu kauka ke hoʻololi i kāu ʻōnaehana lāʻau lapaʻau inā loaʻa iā ʻoe nā hopena ʻaoʻao a i ʻole inā loaʻa nā lāʻau lapaʻau hou, akā pono e hana mau kēia hoʻoholo me ka mālama olakino.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana iā Abacavir a me Lamivudine?

ʻAe ʻia ka inu ʻana i ka waiʻona me ka maʻalahi i ka wā e lawe ana i kēia lāʻau, akā hiki i ka inu nui ke hoʻonui i kou pilikia o nā pilikia o ke ake a hiki ke hoʻopilikia i ka pono o kāu mālama ʻana i ka HIV.

Inā loaʻa iā ʻoe ka maʻi ake a i ʻole ka mōʻaukala o nā pilikia waiʻona, e kūkākūkā i ka hoʻohana ʻana i ka waiʻona me kāu mea mālama ola. Hiki iā lākou ke hāʻawi i ke alakaʻi pilikino e pili ana i kou kūlana olakino.