Abemaciclib (ma ka waha)
Nā mea hōʻailona e loaʻa ana
Verzenio
E pili ana i kēia lāʻau
Hoʻohana pū ʻia ka Abemaciclib me ka tamoxifen a i ʻole ka mea hoʻoemi aromatase (e laʻa, anastrozole, exemestane, letrozole) e mālama i ka maʻi ʻaʻai umauma mua HR-positive, HER-2 negative, node-positive me ka pilikia nui o ka hoʻi hou ʻana e like me ka ʻike a kāu kauka. Hoʻohana pū ʻia ka Abemaciclib me ka mea hoʻoemi aromatase (e laʻa, anastrozole, exemestane, letrozole) ma ke ʻano he mālama hormonal mua e mālama ai i nā kāne a me nā wāhine postmenopausal me ka maʻi ʻaʻai umauma HR-positive, HER-2 negative advanced (maʻi ʻaʻai i ʻoi aku ka ʻino) a i ʻole metastatic (maʻi ʻaʻai i pālahalaha). Hoʻohana pū ʻia ia me ka fulvestrant a i ʻole me ka ʻole e mālama i ka maʻi ʻaʻai umauma HR-positive, HER-2 negative advanced a i ʻole metastatic i nā wāhine i loaʻa ka mālama hormonal a i ʻole nā lāʻau lapaʻau maʻi ʻē aʻe i hana ʻole maikaʻi. Loaʻa ka Abemaciclib i ka hui o nā lāʻau i kapa ʻia ʻo antineoplastics. Hoʻopilikia ia i ka ulu ʻana o nā cell maʻi ʻaʻai, kahi e luku ʻia ai ma hope. ʻOiai hiki ke hoʻopilikia ʻia ka ulu ʻana o nā cell maʻamau e ka lāʻau lapaʻau, e loaʻa pū kekahi mau hopena ʻē aʻe i makemake ʻole ʻia. Hiki ke koʻikoʻi kekahi o kēia mau mea a pono e hōʻike ʻia i kāu kauka. Loaʻa wale kēia lāʻau lapaʻau me ka palapala kauoha a kāu kauka. Loaʻa kēia huahana ma nā ʻano dosage e like me kēia:
Ma mua o ka hoʻohana ʻana i kēia lāʻau
I ka hoʻoholo ʻana e hoʻohana i kahi lāʻau lapaʻau, pono e kaulike i nā pilikia o ka lawe ʻana i ka lāʻau lapaʻau me ka pono e hana ai. He hoʻoholo kēia āu a me kāu kauka e hana ai. No kēia lāʻau lapaʻau, pono e noʻonoʻo i kēia mau mea: E haʻi aku i kāu kauka inā ua loaʻa iā ʻoe kekahi hopena maʻamau ʻole a i ʻole nā allergic i kēia lāʻau lapaʻau a i ʻole nā lāʻau lapaʻau ʻē aʻe. E haʻi aku pū i kāu limahana mālama ola inā loaʻa iā ʻoe nā ʻano allergies ʻē aʻe, e like me nā meaʻai, nā mea kala, nā mea mālama, a i ʻole nā holoholona. No nā huahana ʻole-prescription, e heluhelu pono i ka lepili a i ʻole nā mea hoʻohui pūʻolo. ʻAʻohe mau haʻawina kūpono i hana ʻia ma ka pilina o ka makahiki i nā hopena o ka abemaciclib i ka heluna pediatric. ʻAʻole i hoʻokumu ʻia ka palekana a me ka pono. ʻAʻohe mau haʻawina kūpono i hana ʻia a hiki i kēia lā i hōʻike i nā pilikia geriatric-kūikawā e kaupalena i ka pono o ka abemaciclib i nā ʻelemakule. ʻAʻohe mau haʻawina lawa i nā wāhine no ka hoʻoholo ʻana i ka pilikia o ka pēpē ke hoʻohana nei i kēia lāʻau lapaʻau i ka wā hānai. E kaulike i nā pono hiki ke loaʻa me nā pilikia hiki ke loaʻa ma mua o ka lawe ʻana i kēia lāʻau lapaʻau i ka wā hānai. ʻOiai ʻaʻole pono e hoʻohana pū ʻia kekahi mau lāʻau lapaʻau, i nā hihia ʻē aʻe, hiki ke hoʻohana pū ʻia ʻelua mau lāʻau lapaʻau ʻokoʻa ʻoiai inā hiki ke loaʻa kahi pilina. I kēia mau hihia, makemake paha kāu kauka e hoʻololi i ka nui, a i ʻole nā ʻano palekana ʻē aʻe paha e pono ai. Ke lawe nei ʻoe i kēia lāʻau lapaʻau, he mea nui loa ia i kāu limahana mālama ola e ʻike inā ke lawe nei ʻoe i kekahi o nā lāʻau lapaʻau i helu ʻia ma lalo nei. Ua koho ʻia nā pilina aʻe ma muli o ko lākou koʻikoʻi hiki ke loaʻa a ʻaʻole pono e hoʻokomo piha. ʻAʻole i ʻōlelo ʻia ka hoʻohana ʻana i kēia lāʻau lapaʻau me kekahi o nā lāʻau lapaʻau aʻe. Hiki i kāu kauka ke hoʻoholo ʻaʻole e mālama iā ʻoe me kēia lāʻau lapaʻau a hoʻololi paha i kekahi o nā lāʻau lapaʻau ʻē aʻe āu e lawe nei. ʻAʻole i ʻōlelo ʻia ka hoʻohana ʻana i kēia lāʻau lapaʻau me kekahi o nā lāʻau lapaʻau aʻe, akā hiki ke koi ʻia i kekahi mau hihia. Inā kuhikuhi ʻia nā lāʻau lapaʻau ʻelua, hiki i kāu kauka ke hoʻololi i ka nui a i ʻole ka pinepine o kāu hoʻohana ʻana i hoʻokahi a i ʻole nā lāʻau lapaʻau ʻelua. ʻAʻole pono e hoʻohana ʻia kekahi mau lāʻau lapaʻau i ka wā a i ʻole kokoke i ka wā e ʻai ai i ka meaʻai a i ʻole ka ʻai ʻana i kekahi mau ʻano meaʻai ʻoiai hiki ke loaʻa nā pilina. Hiki i ka hoʻohana ʻana i ka waiʻona a i ʻole ka paka me kekahi mau lāʻau lapaʻau ke hoʻokumu pū i nā pilina. Ua koho ʻia nā pilina aʻe ma muli o ko lākou koʻikoʻi hiki ke loaʻa a ʻaʻole pono e hoʻokomo piha. ʻAʻole i ʻōlelo ʻia ka hoʻohana ʻana i kēia lāʻau lapaʻau me kekahi o nā mea aʻe, akā hiki ke hiki ʻole ke pale ʻia i kekahi mau hihia. Inā hoʻohana pū ʻia, hiki i kāu kauka ke hoʻololi i ka nui a i ʻole ka pinepine o kāu hoʻohana ʻana i kēia lāʻau lapaʻau, a i ʻole e hāʻawi iā ʻoe i nā ʻōlelo kuhikuhi kūikawā e pili ana i ka hoʻohana ʻana i ka meaʻai, ka waiʻona, a i ʻole ka paka. Hiki i ke alo o nā pilikia olakino ʻē aʻe ke hoʻopilikia i ka hoʻohana ʻana i kēia lāʻau lapaʻau. E hōʻoia e haʻi aku i kāu kauka inā loaʻa iā ʻoe nā pilikia olakino ʻē aʻe, ʻoiai:
Pehea e hoʻohana ai i kēia lāʻau
Hoʻoikaika loa nā lāʻau lapaʻau i hoʻohana ʻia e mālama ai i ka maʻi kanesa a hiki ke loaʻa nā hopena ʻaoʻao he nui. Ma mua o ka loaʻa ʻana o kēia lāʻau lapaʻau, e hōʻoia e hoʻomaopopo pono ʻoe i nā pilikia a me nā pono a pau. He mea nui ia no ʻoe ke hana pili pono me kāu kauka i ka wā o kāu mālama ʻana. E lawe i kēia lāʻau lapaʻau e like me ke kuhikuhi a kāu kauka. Mai lawe hou aku, mai lawe pinepine aku, a mai lawe lōʻihi aku ma mua o ka kauoha a kāu kauka. Hiki mai kēia lāʻau lapaʻau me kahi palapala ʻike no nā mea maʻi. E heluhelu a hahai pono i kēia mau ʻōlelo kuhikuhi. E nīnau i kāu kauka inā he nīnau kāu. E ʻaila i ka papahele holoʻokoʻa. Mai haki, wāwahi, a ʻai paha. E lawe i kēia lāʻau lapaʻau i ka manawa hoʻokahi i kēlā me kēia lā, me ka ʻai ʻole paha. Mai ʻai i ka pomelo a inu i ka wai pomelo ʻoiai ʻoe e hoʻohana ana i kēia lāʻau lapaʻau. E ʻokoʻa ka nui o kēia lāʻau lapaʻau no nā mea maʻi like ʻole. E hahai i nā kauoha a kāu kauka a i ʻole nā kuhikuhi ma ka lepili. ʻO ka ʻike ma lalo nei e komo wale nō i nā nui awelika o kēia lāʻau lapaʻau. Inā ʻokoʻa kāu nui, mai hoʻololi inā ʻaʻole i haʻi aku kāu kauka iā ʻoe e hana pēlā. ʻO ka nui o ka lāʻau lapaʻau āu e lawe ai e hilinaʻi ana i ka ikaika o ka lāʻau lapaʻau. Eia kekahi, ʻo ka nui o nā nui āu e lawe ai i kēlā me kēia lā, ka manawa i ʻae ʻia ma waena o nā nui, a me ka lōʻihi o ka manawa āu e lawe ai i ka lāʻau lapaʻau e hilinaʻi ana i ka pilikia olakino āu e hoʻohana nei i ka lāʻau lapaʻau. Inā nalowale ʻoe i kahi nui o kēia lāʻau lapaʻau, e haʻalele i ka nui i nalowale a hoʻi i kāu papa hana maʻamau. Mai pāpālua i nā nui. Inā luaʻi ʻoe ma hope o ka lawe ʻana i kēia lāʻau lapaʻau, mai lawe hou i kahi nui i ka lā hoʻokahi. E kali a hiki i kāu nui aʻe a lawe iā ia i ka manawa maʻamau āu e hana ai. E mālama i ka lāʻau lapaʻau i loko o kahi pahu pani ʻia ma ka mahana o ka lumi, mamao aku i ka wela, ka pulu, a me ka mālamalama pololei. E mālama mai ka hau. E mālama i kahi mamao aku o nā keiki. Mai mālama i ka lāʻau lapaʻau kahiko a i ʻole ka lāʻau lapaʻau ʻaʻole pono hou. E nīnau i kāu limahana olakino pehea ʻoe e hoʻolei ai i kekahi lāʻau lapaʻau āu ʻaʻole e hoʻohana.
Hōʻole: He kahua ʻike olakino ʻo ʻAukake a ʻaʻole hōʻike kāna mau pane i ka ʻōlelo aʻoaʻo lapaʻau. E kūkākūkā mau me kahi ʻoihana lapaʻau laikini kokoke iā ʻoe ma mua o ka hana ʻana i nā hoʻololi.
Hana ʻia i India, no ka honua