He aha ʻo Abiraterone: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau maʻi maʻi ʻo Abiraterone e kōkua ana i ka hakakā ʻana i ka maʻi maʻi prostate holomua ma ka pale ʻana i ka hana ʻana o ka testosterone. Hana kēia lāʻau lapaʻau waha ma ka hoʻōki ʻana i kou kino mai ka hana ʻana i nā hormones e hoʻoulu ai i kekahi mau ʻano o nā sela maʻi maʻi prostate, e pōloli ana i ka maʻi maʻi i ka mea e pono ai e ulu.

Inā ua kau ʻia ʻo abiraterone iā ʻoe a i ʻole kekahi mea aloha, e hana ana paha ʻoe me ka maʻi maʻi prostate holomua i laha ma waho o ka ʻōpū prostate. Hiki i kēia ke manaʻo nui, akā ʻo ka hoʻomaopopo ʻana i ke ʻano o ka hana ʻana o kēia lāʻau lapaʻau hiki ke kōkua iā ʻoe e mākaukau a hilinaʻi i kāu huakaʻi lapaʻau.

He aha ʻo Abiraterone?

He lāʻau lapaʻau hormone therapy ʻo Abiraterone i hoʻolālā ʻia e mālama i ka maʻi maʻi prostate metastatic. ʻO ke ʻano

Hiki i kāu kauka ke kuhikuhi iā abiraterone inā ua holomua kāu maʻi maʻi prostate me ka nānā ʻole i nā lāʻau hormone ʻē aʻe a i ʻole ka wehe ʻana i ke ʻoki ʻana i ka ʻiʻo e hana ana i ka testosterone. Hoʻohana pinepine ʻia ia i ka wā i laha ai ka maʻi maʻi i nā iwi, nā lymph nodes, a i ʻole nā ​​ʻōkana ʻē aʻe, a ʻaʻole e kāohi hou nā lāʻau lapaʻau maʻamau i ka maʻi.

I kekahi mau hihia, kuhikuhi nā kauka iā abiraterone no ka maʻi maʻi prostate hormone-sensitive metastatic me nā lāʻau lapaʻau ʻē aʻe. Kōkua kēia ala i ka pale ʻana i ka maʻi maʻi mai ka lilo ʻana i mea kūʻē i ka lāʻau hormone a hiki ke hoʻolōʻihi i ka manawa ma mua o ka holomua ʻana o ka maʻi.

Pehea e hana ai ʻo Abiraterone?

Hana ʻo Abiraterone ma ka pale ʻana i kahi enzyme i kapa ʻia ʻo CYP17A1, a ka mea e hoʻohana ai kou kino e hana i ka testosterone a me nā androgens ʻē aʻe. Hoʻopili maʻamau nā cell maʻi prostate i kēia mau hormones e ola a hoʻonui, no laila hiki i ka ʻoki ʻana i kā lākou lako ke lohi a hoʻōki paha i ka ulu ʻana o ka maʻi maʻi.

Ua manaʻo ʻia kēia lāʻau lapaʻau he koho lapaʻau ikaika a maikaʻi no ka maʻi maʻi prostate holomua. Hoʻopaʻa ia i ka hana hormone ʻaʻole wale i loko o kou mau testicles, akā i loko nō hoʻi o kou mau adrenal glands a me nā cell maʻi maʻi. ʻO kēia ala ākea e paʻakikī ai i nā cell maʻi maʻi ke loaʻa nā hormones e pono ai lākou.

Hoʻomaka maʻamau ka lāʻau lapaʻau i loko o kekahi mau pule, ʻoiai ʻaʻole paha ʻoe e ʻike i nā loli koke. E nānā kāu kauka i kāu mau pae PSA (prostate-specific antigen) a me nā mea hōʻailona koko ʻē aʻe e nānā i ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau iā ʻoe.

Pehea wau e lawe ai iā Abiraterone?

E lawe iā abiraterone e like me ke kauoha a kāu kauka, maʻamau hoʻokahi manawa i ka lā ma ka ʻōpū ʻole. ʻO ia hoʻi, pono ʻoe e lawe iā ia ma kahi o hoʻokahi hola ma mua o ka ʻai ʻana a i ʻole ʻelua hola ma hope o ka ʻai ʻana, no ka mea, hiki i ka meaʻai ke hoʻonui nui i ka nui o ka lāʻau lapaʻau e komo ai kou kino.

E ale i nā papa holoʻokoʻa me ke aniani wai piha. Mai ʻoki, wāwahi, a nau paha i nā papa, no ka mea, hiki i kēia ke hoʻopilikia i ke ʻano o ka hoʻokuʻu ʻia ʻana o ka lāʻau lapaʻau i loko o kou kino. ʻO ka lawe ʻana i ka manawa like i kēlā me kēia lā e kōkua i ka mālama ʻana i nā pae kūlike o ka lāʻau i loko o kou ʻōnaehana.

Pono nō hoʻi ʻoe e lawe i ka prednisone a i ʻole prednisolone me abiraterone. Kōkua kēia lāʻau steroid i ka pale ʻana i nā hopena ʻaoʻao e pili ana i nā loli hormone a he ʻāpana nui ia o kāu hana lapaʻau. E kauoha kāu kauka i ke ana kūpono a me ka papa manawa no nā lāʻau lapaʻau ʻelua.

Pehea ka lōʻihi e lawe ai au i ka Abiraterone?

E hoʻomau maʻamau ʻoe i ka lawe ʻana i ka abiraterone inā e kāohi ana ia i kāu maʻi kanesa a ke ʻae maikaʻi nei ʻoe iā ia. Hiki i kēia ke mau mahina a i ʻole mau makahiki, ma muli o ke ʻano o ka pane ʻana o kou kino i ka lapaʻau.

E nānā kāu kauka i kāu holomua ma o nā hoʻokolohua koko maʻamau, nā kiʻi kiʻi, a me nā hoʻokolohua kino. Inā hoʻomaka kāu pae PSA e piʻi mau a i ʻole e hōʻike nā kiʻi i ka holomua o ka maʻi kanesa, hiki i kāu kauka ke hoʻoponopono i kāu hoʻolālā lapaʻau a i ʻole e hoʻololi i nā lāʻau lapaʻau like ʻole.

Lawe kekahi poʻe i ka abiraterone no nā manawa lōʻihi me nā hopena maikaʻi, aʻo nā mea ʻē aʻe e pono e hoʻololi i nā lapaʻau i ka wā ma mua. E alakaʻi kāu pane pilikino i ka lōʻihi o kou hoʻomau ʻana me kēia lāʻau lapaʻau, a e hana pū kāu hui mālama ola me ʻoe e hana i nā hoʻoholo maikaʻi loa no kou kūlana.

He aha nā hopena ʻaoʻao o Abiraterone?

E like me nā lāʻau lapaʻau maʻi kanesa a pau, hiki i ka abiraterone ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole i loaʻa i nā mea a pau. Hiki ke mālama ʻia ka hapa nui o nā hopena ʻaoʻao, a e nānā pono kāu hui mālama ola iā ʻoe e hoʻoponopono i nā pilikia e kū mai ana.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia ka luhi, ka ʻeha hui, ka pehu ʻana i kou mau wāwae a i ʻole nā wāwae, nā wela wela, a me ka maʻi maʻi. Hoʻomaikaʻi pinepine kēia mau hopena i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau, a aia nā ala e mālama pono ai iā lākou.

Hiki i nā hopena ʻinoʻino, akā ʻaʻole maʻamau, ke komo i nā pilikia o ke ake, ke koko kiʻekiʻe, nā pae potassium haʻahaʻa, a me nā loli o ka puʻuwai. E nānā mau kāu kauka i kou koko e ʻike koke i kēia mau pilikia. Loaʻa kekahi mau kāne i ka nāwaliwali o nā ʻiʻo, ka ʻeha o ka iwi, a i ʻole nā loli i nā pae kōpaʻa koko.

I kekahi manawa, hiki i ka abiraterone ke hana i ka pōʻino nui o ke ake, nā pilikia o ka puʻuwai, a i ʻole nā hāʻule weliweli i ke koko. ʻO ia ke kumu e koʻikoʻi ai ka nānā mau ʻana. Inā ʻike ʻoe i ka melemele o kou ʻili a i ʻole nā maka, ka luhi nui, ka ʻeha o ka umauma, a i ʻole ka pilikia o ka hanu ʻana, e hoʻokaʻaʻike koke i kāu mea mālama ola.

ʻO wai ka mea ʻaʻole pono e lawe i ka Abiraterone?

ʻAʻole kūpono ka Abiraterone no nā mea a pau, a e loiloi pono kāu kauka inā kūpono ia iā ʻoe. ʻAʻole hiki i nā poʻe me ka maʻi ake nui ke lawe i kēia lāʻau, no ka mea, hiki iā ia ke hoʻonui i nā pilikia o ke ake.

Inā he moʻolelo kou o nā pilikia o ka puʻuwai, ke koko kiʻekiʻe ʻole i ka mana, a i ʻole kekahi mau maʻi o ka puʻuwai, pono kāu kauka e kaupaona pono i nā pōmaikaʻi e kūʻē i nā pilikia. Hiki i ka lāʻau lapaʻau ke hoʻopilikia i kou puʻuwai a me ke koko, no laila pono kēia mau kūlana i ka nānā kūikawā.

ʻAʻole pono nā wahine hāpai a i ʻole e hāpai ana e mālama i nā papa abiraterone, no ka mea, hiki i ka lāʻau lapaʻau ke hōʻino i kahi pēpē e ulu ana. Pono nā kāne e lawe ana i ka abiraterone e hoʻohana i ka mana hānau pono inā hiki i kā lākou hoa ke hāpai, no ka mea, hiki ke loaʻa ka lāʻau lapaʻau i ka semen.

E noʻonoʻo pū kāu kauka i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei, no ka mea, hiki i ka abiraterone ke launa pū me nā mea lahilahi koko, kekahi mau lāʻau lapaʻau puʻuwai, a me nā lāʻau ʻē aʻe e pili ana i ka hana o ke ake.

Nā inoa inoa o Abiraterone

Loaʻa ka Abiraterone ma lalo o nā inoa inoa like ʻole, ʻo Zytiga ka inoa inoa mua i ʻike nui ʻia. ʻO kēia ka mana mua i ʻae ʻia e ka FDA o ka abiraterone acetate a ua hana ʻia e Janssen Pharmaceuticals.

Ua loaʻa nā ʻano generic o ka abiraterone mai nā mea hana like ʻole, hiki ke hoʻemi i ke kumukūʻai o ka lāʻau. Aia i loko o kēia mau ʻano generic ka mea hana like a hana like me ka lāʻau inoa inoa.

Hiki i kāu hale kūʻai lāʻau lapaʻau ke mālama i nā inoa like ʻole a i ʻole nā ʻano generic, akā he lāʻau lapaʻau like nō lākou. Inā he nīnau kāu e pili ana i ka ʻano āu e loaʻa nei, hiki i kāu kauka lāʻau lapaʻau ke wehewehe i nā ʻokoʻa a kōkua e hōʻoia e loaʻa ana iā ʻoe ke koho kūpono loa i ke kumukūʻai.

Nā Koho ʻē aʻe no Abiraterone

Inā ʻaʻole kūpono ka abiraterone iā ʻoe a i ʻole e pau ka hana ʻana, aia kekahi mau koho lapaʻau ʻē aʻe no ka maʻi kanesa prostate holomua. ʻO Enzalutamide (Xtandi) kekahi ʻano lapaʻau hormone e hana ana i nā ʻano like ʻole akā e kuhikuhi ana i nā ala like.

Hoʻohana pinepine ʻia ka chemotherapy Docetaxel no ka maʻi kanesa prostate metastatic, inā paha wale nō a i hui pū ʻia me nā lapaʻau hormone. Hiki i nā lapaʻau hou e like me ka radium-223 (Xofigo) ke kōkua inā ua laha ka maʻi kanesa i nā iwi, ʻoiai ʻo sipuleucel-T (Provenge) he koho immunotherapy.

Hiki i kāu kauka ke noʻonoʻo i nā hoʻokolohua lapaʻau o nā lapaʻau hoʻokolohua, ʻoi aku hoʻi inā ʻaʻole e hana maikaʻi nā lapaʻau maʻamau. Ke hoʻomau nei ke ʻano o ka lapaʻau ʻana i ka maʻi kanesa prostate, me nā lāʻau lapaʻau hou a me nā hui e hoʻomohala mau ʻia nei.

ʻOi aku ka maikaʻi o ka Abiraterone ma mua o Enzalutamide?

He mau lapaʻau maikaʻi ʻo Abiraterone a me enzalutamide no ka maʻi kanesa prostate holomua, akā hana lākou i nā ʻano like ʻole. Kāohi ʻo Abiraterone i ka hana ʻana o ka hormone, ʻoiai ʻo enzalutamide e kāohi i ke ʻano o ka hoʻohana ʻana o nā cella maʻi kanesa i nā hormones i loaʻa mua.

Hōʻike ka noiʻi e hiki i nā lāʻau lapaʻau ʻelua ke hoʻolōʻihi i ke ola a hoʻomaikaʻi i ka maikaʻi o ke ola no nā kāne me ka maʻi kanesa prostate metastatic. ʻO ke koho ma waena o lākou e hilinaʻi pinepine ʻia i kāu kūlana kikoʻī, nā kūlana olakino ʻē aʻe, a me ke ʻano o kāu pane ʻana i ka lapaʻau.

ʻOi aku ka maikaʻi o kekahi poʻe me kekahi lāʻau lapaʻau ma mua o kekahi, a e noʻonoʻo kāu kauka i nā mea e like me kou olakino i kēia manawa, nā lāʻau lapaʻau ʻē aʻe āu e lawe nei, a me nā hopena ʻaoʻao e hiki mai ana i ka wā e hana ai i nā ʻōlelo paipai. Ua manaʻo ʻia lāua ʻelua he mau lapaʻau mua no ka maʻi kanesa prostate holomua.

Nā Nīnau i Nīnau pinepine ʻia e pili ana iā Abiraterone

Q1. Palekana anei ʻo Abiraterone no ka poʻe me ka maʻi puʻuwai?

Hiki ke hoʻohana ʻia ʻo Abiraterone i ka poʻe me ka maʻi puʻuwai, akā pono ia i ka nānā ʻana a me ka mālama ʻana. Hiki i ka lāʻau lapaʻau ke hoʻopilikia i ke koko a me ka puʻuwai, no laila pono kāu cardiologist a me ka oncologist e hana pū e hōʻoia i kou palekana.

E nānā paha kāu kauka i kou puʻuwai, e nānā mau i kou koko, a e hoʻoponopono paha i nā lāʻau lapaʻau puʻuwai ʻē aʻe āu e lawe nei. Nui ka poʻe me nā maʻi puʻuwai e hiki ke pōmaikaʻi mai ka lapaʻau abiraterone ke mālama pono ʻia.

Q2. He aha kaʻu e hana ai inā lawe hewa au i ka nui o Abiraterone?

Inā lawe hewa ʻoe i ka nui o ka abiraterone ma mua o ka mea i kauoha ʻia, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena hoʻomalu lāʻau make. ʻO ka lawe ʻana i ka nui hiki ke hoʻonui i kou pilikia o nā hopena ʻaoʻao koʻikoʻi, ʻo ia hoʻi nā pilikia o ke ake a me nā loli o ka puʻuwai.

Mai kali e ʻike inā maikaʻi ʻoe. ʻOiai inā ʻaʻole ʻoe e ʻike i nā hōʻailona koke, hiki i ka overdose ke hoʻoulu i nā hopena lohi e pono ai ka mālama olakino. Hiki i kāu hui mālama ola ke aʻo iā ʻoe i ka mea e nānā ai a inā pono ʻoe i ka mālama olakino koke.

Q3. He aha kaʻu e hana ai inā haʻalele au i kahi mahele o Abiraterone?

Inā haʻalele ʻoe i kahi mahele o ka abiraterone, e lawe koke iā ia ke hoʻomanaʻo ʻoe, akā inā he emi iho ia o 12 mau hola mai kou manawa i hoʻonohonoho ʻia. Inā ʻoi aku ia ma mua o 12 mau hola, e lele i ka mahele i haʻalele ʻia a lawe i kāu mahele aʻe i ka manawa maʻamau.

Mai lawe i nā lāʻau ʻelua i ka manawa hoʻokahi e pani ai i ka lāʻau i hala, no ka mea, hiki i kēia ke hoʻonui i kou pilikia o nā hopena ʻaoʻao. Inā poina pinepine ʻoe i nā lāʻau, e noʻonoʻo e hoʻonohonoho i nā mea hoʻomanaʻo kelepona a i ʻole e hoʻohana i kahi mea hoʻonohonoho pila e kōkua iā ʻoe e noho ma ke ala.

Q4. I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Abiraterone?

Pono ʻoe e hooki i ka lawe ʻana iā abiraterone ke ʻōlelo aku kāu kauka iā ʻoe e hana pēlā. Hana maʻamau kēia inā holomua ka maʻi maʻi me ka mālama ʻana, inā loaʻa iā ʻoe nā hopena ʻaoʻao koʻikoʻi, a i ʻole inā ʻōlelo kāu kauka e hoʻololi i kahi ala lapaʻau ʻē aʻe.

Mai hooki i ka lawe ʻana iā abiraterone me ka ʻole o ka nānā ʻana i ka lāʻau lapaʻau, no ka mea, hiki i kēia ke ʻae i kāu maʻi maʻi e holomua wikiwiki. E nānā mau kāu kauka i kou kūlana a kūkākūkā i nā loli i kāu hoʻolālā lapaʻau me ʻoe.

Q5. Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana iā Abiraterone?

ʻOi aku ka maikaʻi e kaupalena i ka ʻai ʻana i ka waiʻona i ka wā e lawe ana iā abiraterone, no ka mea, hiki i ka waiʻona a me ka lāʻau lapaʻau ke hoʻopilikia i kou ate. He maikaʻi ka inu ʻana i kekahi manawa, akā pono ʻoe e kūkākūkā i kēia me kāu kauka ma muli o kou kūlana pilikino.

Inā he pilikia kou ate a i ʻole e lawe i nā lāʻau ʻē aʻe e pili ana i ka ate, hiki i kāu kauka ke ʻōlelo e pale loa i ka waiʻona. Hiki i kāu hui mālama ola ke hāʻawi i ke alakaʻi pilikino e pili ana i kou olakino holoʻokoʻa a me ka hoʻolālā lapaʻau.