He aha ʻo Aflibercept (Ala Intraocular): Nā Hoʻohana, Ka Leka, Nā ʻAoʻao ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau ʻo Aflibercept i hoʻokomo pololei ʻia i loko o kou maka e mālama i nā pilikia ʻike koʻikoʻi i hana ʻia e ka ulu ʻana o nā kīʻaha koko maʻamau ʻole. Hana kēia lāʻau lapaʻau i kauoha ʻia ma ka pale ʻana i kekahi mau protein e hoʻoulu ai i nā kīʻaha koko e kahe a ulu i kahi ʻaʻole pono i loko o kou retina.

Inā ua ʻōlelo kāu kauka i nā injections aflibercept, ke hana nei paha ʻoe me kahi maʻi e pili ana i ka hope o kou maka. ʻOiai ʻo ka manaʻo o ka injection maka e manaʻo nui paha, ua kōkua kēia lapaʻau i nā miliona o nā kānaka e mālama a hoʻomaikaʻi i ko lākou ʻike i ka wā i hana ʻole ai nā koho ʻē aʻe.

He aha ʻo Aflibercept?

He protein i hana ʻia e ka lab ʻo Aflibercept e hoʻohālike i ka hiki maoli o kou kino e kāohi i ka ulu ʻana o nā kīʻaha koko. E noʻonoʻo iā ia he lāʻau lapaʻau i manaʻo ʻia e hele pololei i kahi e hana nei ka pilikia i kou maka.

No ka papa o nā lāʻau lapaʻau i kapa ʻia ʻo VEGF inhibitors ka lāʻau lapaʻau, ʻo ia hoʻi nā mea pale i ka vascular endothelial growth factor. Ma nā huaʻōlelo maʻalahi, hoʻōki ia i nā hōʻailona e haʻi ana i nā kīʻaha koko i hōʻino ʻia e ulu a kahe i ka wai i loko o kou retina.

E hoʻokomo kāu kauka maka i kēia wai maopopo i loko o ka mea gel-like i loko o kou maka i kapa ʻia ʻo vitreous. Hiki i kēia i ka lāʻau lapaʻau ke hana pololei i kahi e pono ai, ma mua o ka hele ʻana i kou kino holoʻokoʻa e hiki ai i kou maka.

No ke aha e hoʻohana ʻia ai ʻo Aflibercept?

Hoʻomaʻamaʻa ʻo Aflibercept i kekahi mau maʻi maka koʻikoʻi e hiki ke hoʻoweliweli i kou ʻike. Ua ʻōlelo paha kāu kauka iā ia no ka mea ke kumu nei nā kīʻaha koko maʻamau ʻole i kou maka i ka wai a i ʻole ke kahe ʻana e pili ana i kou ʻike.

ʻO nā maʻi maʻamau i mālama ʻia me ka aflibercept e pili ana i ka degeneration macular e pili ana i ka makahiki, diabetic macular edema, a me ka diabetic retinopathy. Hoʻopili kēlā me kēia o kēia mau maʻi i nā kīʻaha koko e kahe ana i ka wai a i ʻole e ulu ana i nā wahi kahi e pono ʻole ai lākou.

Eia nā maʻi maka kikoʻī e hiki ai i ka aflibercept ke kōkua i ka mālama ʻana:

• ʻO ka degeneration macular e pili ana i ka makahiki (AMD) - ke ulu nā kīʻaha koko maʻamau ma lalo o kou macula a kahe ka wai
• ʻO ka edema macular diabetic - ka hōʻiliʻili wai i loko o kou macula i hoʻokumu ʻia e ka maʻi diabetes
• ʻO ka retinopathy diabetic - ka pōʻino i nā kīʻaha koko i loko o kou retina mai ka maʻi diabetes
• ʻO ka edema macular ma hope o ka occlusion vein retinal - ka pehu ʻana ma hope o ka pani ʻia ʻana o ke kīʻaha koko i loko o kou retina

Hiki i kēia mau maʻi ke hoʻopōʻino i ka ʻike, nā kiko ʻeleʻele, a i ʻole ka pilikia i ka ʻike ʻana i nā kikoʻī maikaʻi. Me ka ʻole o ka mālama ʻana, hiki iā lākou ke alakaʻi i ka nalowale ʻana o ka ʻike mau, ʻo ia ke kumu i ʻōlelo ai kāu kauka e hoʻomaka i nā injections aflibercept.

Pehea e Hana ai ʻo Aflibercept?

Hana ʻo Aflibercept ma ka pale ʻana i nā hōʻailona ulu e hoʻokumu ai i nā kīʻaha koko pilikia a kahe i loko o kou maka. Ua manaʻo ʻia he lāʻau lapaʻau ikaika a maikaʻi hoʻi no ka mālama ʻana i nā maʻi maka e hoʻoweliweli ana i ka ʻike.

Ke hoʻouna kekahi mau protein i loko o kou maka i nā hōʻailona no ka ulu ʻana o nā kīʻaha koko hou, komo ʻo aflibercept a pale i kēlā mau hōʻailona. Kōkua kēia i ka hoʻōki ʻana i ka ulu ʻana o nā kīʻaha koko maʻamau a hoʻemi i ka leakage wai e hiki ke hōʻino i kou ʻike.

Kōkua ka lāʻau lapaʻau i nā kīʻaha koko maʻamau e lilo i mea paʻa a ʻaʻole e kahe. I ka wā lōʻihi, hiki i kēia ke hōʻemi i ka pehu ʻana i loko o kou retina a kōkua i ka mālama ʻana a i ʻole ka hoʻomaikaʻi ʻana i kou ʻike.

Hoʻomaka ka hapa nui o nā kānaka e ʻike i nā hoʻomaikaʻi ʻana i loko o kekahi mau pule a i kekahi mau mahina ma hope o ka hoʻomaka ʻana i ka mālama ʻana. Eia naʻe, lawe pinepine nā pōmaikaʻi piha i kekahi mau injections e lilo i mea maopopo, no ka mea, pono ka manawa o kou maka e hoʻōla a hoʻopaʻa.

Pehea wau e lawe ai i ka Aflibercept?

Hāʻawi ʻia ʻo Aflibercept ma ke ʻano he injection pololei i loko o kou maka e kāu kauka maka i loko o kā lākou keʻena a i ʻole kahi keʻena outpatient. ʻAʻole hiki iā ʻoe ke lawe i kēia lāʻau lapaʻau ma ka home, a ʻaʻole loaʻa ia ma ke ʻano he kulu maka a i ʻole nā ​​pills.

Ma mua o kāu pahu, e hoʻopāpā kāu kauka i kou maka me nā kulu e hōʻoluʻolu ai ke kaʻina hana. E hoʻomaʻemaʻe nō hoʻi lākou i kou maka a me kou lihilihi e pale ai i ka maʻi.

He mau kekona wale nō ke komo ʻana i ka pahu, akā, ma kahi o 30 mau minuke ka manawa o ka hālāwai holoʻokoʻa. E nānā kāu kauka iā ʻoe ma hope koke o ka pahu e hōʻoia ana e maikaʻi ana ʻoe.

ʻAʻole pono ʻoe e pale i ka ʻai ʻana a i ʻole ka inu ʻana ma mua o kāu hālāwai, a hiki iā ʻoe ke lawe i kāu mau lāʻau maʻamau e like me ka mea maʻamau. Eia naʻe, pono ʻoe e hoʻonohonoho i kekahi e hoʻokele iā ʻoe i ka home, no ka mea, e pōpō paha kou ʻike ma hope koke o ka pahu.

Pehea ka lōʻihi e lawe ai au i ka Aflibercept?

He ʻokoʻa ka lōʻihi o ka mālama ʻana i ka aflibercept ma muli o kou kūlana kikoʻī a me ka maikaʻi o kou pane ʻana i ka lāʻau. Pono ka hapa nui o nā kānaka i ka mālama mau ʻana no nā mahina a i ʻole nā makahiki e mālama i kā lākou hoʻomaikaʻi ʻana i ka ʻike.

I ka wā mua, e loaʻa paha iā ʻoe nā pahu i kēlā me kēia 4 a 8 pule no nā mahina mua. E nānā pono kāu kauka i kāu holomua a hiki ke hoʻoponopono i ke alapine ma muli o ke ʻano o ka pane ʻana o kou maka.

Ma hope o ka mālama mua ʻana, hiki i kekahi poʻe ke hoʻokaʻawale i kā lākou mau pahu i kēlā me kēia 8 a 12 pule. Pono paha kekahi poʻe e hoʻomau me nā pahu pinepine e mālama i kā lākou loaʻa ʻana o ka ʻike.

ʻO nā kūlana e mālama ai ka aflibercept he maʻamau, ʻo ia hoʻi, pono lākou i ka mālama lōʻihi. ʻO ka hoʻōki ʻana i ka mālama ʻana i ka wā mua e alakaʻi pinepine i ka hoʻi ʻana o ke kūkulu ʻana o ka wai a me nā pilikia o ka ʻike, no laila he mea nui e hahai i ka papa manawa i ʻōlelo ʻia e kāu kauka.

He aha nā hopena ʻaoʻao o Aflibercept?

E like me nā lāʻau a pau, hiki i ka aflibercept ke hana i nā hopena ʻaoʻao, akā, ua ʻae ka hapa nui o nā kānaka i nā pahu. ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a me ka manawa, e pili ana i kou maka no kekahi mau lā ma hope o ka pahu.

Hiki i ka ʻike ʻana i ka mea e manaʻo ai ke kōkua iā ʻoe e mākaukau a ʻike i ka manawa e hoʻokaʻaʻike aku ai i kāu kauka. ʻO ka hapa nui o nā hopena ʻaoʻao e pili ana i ke kaʻina hana injection ponoʻī ma mua o ka lāʻau.

Eia nā hopena ʻaoʻao maʻamau e hiki ai iā ʻoe ke ʻike:

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• ʻEha maka a i ʻole ka hōʻoluʻolu ʻole e hoʻomaikaʻi maʻamau i loko o hoʻokahi a ʻelua paha lā
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• ʻIke pōʻeleʻele no kekahi manawa ma hope koke o ka injection
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• Ka manaʻo e like me ka mea i loko o kou maka (manaʻo kino ʻē)
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• Hoʻonui ʻia ka hana waimaka a i ʻole nā maka wai
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• ʻUlaʻula maka māmā a i ʻole ka huhū
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• ʻIke i nā kiko lana liʻiliʻi a i ʻole

  ʻAʻole pono ʻoe e loaʻa i ka aflibercept inā he maʻi ola kou i loko a i ʻole a puni kou maka. Pono e hoʻomaʻemaʻe loa ʻia kekahi maʻi maka ma mua o ka hoʻomaka ʻana i nā injections e pale aku i nā pilikia koʻikoʻi.

  Pono nā kānaka me nā allergies i ʻike ʻia i ka aflibercept a i ʻole kekahi o kāna mau mea e pale i kēia lāʻau. Inā ua loaʻa iā ʻoe kahi hopena maʻi koʻikoʻi i nā lāʻau lapaʻau injection maka like, e ʻōlelo paha kāu kauka i nā lāʻau lapaʻau ʻē aʻe.

  E noʻonoʻo pū kāu kauka i kēia mau mea i ka wā e hoʻoholo ai inā kūpono ka aflibercept iā ʻoe:

  • ʻO ka ʻoki maka hou a i ʻole ka ʻeha i ʻole i ola piha
  • Ke koko kiʻekiʻe koʻikoʻi ʻaʻole i mālama maikaʻi ʻia
  • Mōʻaukala o ka hahau ʻana a i ʻole nā ​​koko koko, ʻoi aku ka mea hou
  • Hāpai a i ʻole nā ​​plana e hāpai
  • Hānai ʻana i ka waiū
  • Nā maʻi maka koʻikoʻi ʻē aʻe e hiki ke hoʻopilikia i ka lāʻau

  Inā loaʻa iā ʻoe ka maʻi diabetes, ka maʻi puʻuwai, a i ʻole nā ​​maʻi maʻi ʻē aʻe, e noʻonoʻo pono kāu kauka i nā pōmaikaʻi a me nā pilikia. ʻAʻole kēia mau maʻi e hoʻokuʻu ʻakomi iā ʻoe mai ka lāʻau lapaʻau, akā pono paha lākou i ka nānā ʻana.

  Nā inoa inoa o Aflibercept

Loaʻa ka Aflibercept no nā injections maka ma lalo o ka inoa inoa Eylea ma ka hapa nui o nā ʻāina. ʻO kēia ke ʻano i kauoha pinepine ʻia o ka aflibercept no ka mālama ʻana i nā maʻi maka.

E kuhikuhi paha kāu palapala kauoha a me ka ʻinikua iā ia ʻo Eylea, ʻoiai ʻo ka mea hana ikaika ʻo aflibercept. Loaʻa paha i kekahi mau hoʻolālā ʻinikua nā koi kikoʻī a i ʻole nā ​​hana ʻae mua no kēia lāʻau.

Aia kekahi formulation hou i kapa ʻia ʻo Eylea HD, a he kiʻekiʻe ka nui o ka aflibercept. Hiki i kēia ke hoʻemi i nā injections i kekahi mau hihia, akā ʻaʻole kūpono ia no nā maʻi a i ʻole nā ​​maʻi āpau.

Nā koho ʻē aʻe o Aflibercept

He nui nā lāʻau lapaʻau ʻē aʻe e hiki ke mālama i nā maʻi maka like inā ʻaʻole kūpono ka aflibercept iā ʻoe a i ʻole ʻaʻole e hāʻawi i nā hopena kūpono. Hiki i kāu kauka ke noʻonoʻo i kēia mau koho ʻē aʻe e pili ana i kāu kūlana kikoʻī a me ka mōʻaukala olakino.

Hana like nā mea pale VEGF ʻē aʻe me ka aflibercept a hiki ke hana like no kou maʻi. Aia kēia mau mea i ka ranibizumab (Lucentis) a me ka bevacizumab (Avastin), i hāʻawi ʻia hoʻi ma ke ʻano he injections maka.

Eia nā koho nui e hiki i kāu kauka ke noʻonoʻo:

• Ranibizumab (Lucentis) - he mea pale VEGF ʻē aʻe i ʻae ʻia e ka FDA no nā maʻi like
• Bevacizumab (Avastin) - he lāʻau lapaʻau maʻi maʻi i hoʻohana mua ʻia no nā maʻi maka
• Brolucizumab (Beovu) - he mea pale VEGF hou e koi ana i nā injections liʻiliʻi
• Faricimab (Vabysmo) - e kālele ana i nā ala he nui a hiki ke hoʻolōʻihi i ka manawa ma waena o nā injections

I kekahi mau hihia, hiki i kāu kauka ke ʻōlelo aku i ka laser therapy, steroid injections, a i ʻole nā kaʻina hana ʻokiʻoki ma ke ʻano he koho ʻē aʻe a i ʻole nā mea hoʻohui i nā injections mea pale VEGF. ʻO ke koho maikaʻi loa e pili ana i kāu maʻi kikoʻī, pehea ka holomua ʻana, a pehea ʻoe i pane ai i nā lāʻau lapaʻau mua.

Ua ʻoi aku ka maikaʻi o Aflibercept ma mua o Ranibizumab (Lucentis)?

He mau lāʻau lapaʻau maikaʻi loa ʻo Aflibercept a me ranibizumab no ka mālama ʻana i nā maʻi maka koʻikoʻi, a hōʻike ka noiʻi e hana like lākou no ka hapa nui o nā kānaka. ʻO ke koho ma waena o lākou e pili pinepine ana i nā mea pilikino ma mua o ka ʻoi aku ka maikaʻi o kekahi.

Ua ʻike nā haʻawina e hiki i nā lāʻau lapaʻau ʻelua ke hoʻomaikaʻi nui i ka ʻike a pale i ka nalowale ʻana o ka ʻike i nā kānaka me nā maʻi e like me ka degeneration macular pulu a me ka maʻi maka diabetic. Pane maikaʻi ka hapa nui o nā kānaka i kekahi lāʻau lapaʻau.

ʻO ka ʻokoʻa nui, ʻo ia paha e ʻae ʻo aflibercept i nā manawa lōʻihi ma waena o nā injections i kekahi poʻe. ʻOiai hāʻawi ʻia ʻo ranibizumab i kēlā me kēia 4 pule i ka wā mua, hiki ke hoʻolōʻihi ʻia ʻo aflibercept i kēlā me kēia 8 pule ma hope o ka mālama mua.

Na kāu kauka e koho i ka lāʻau lapaʻau maikaʻi loa nāu e pili ana i nā mea he nui me kou kūlana kikoʻī, ka uhi ʻinikua, a me ke ʻano o kou pane ʻana i ka mālama ʻana. Hiki i kekahi poʻe ke hoʻololi ma waena o nā lāʻau lapaʻau inā ʻaʻole i hāʻawi kā lākou koho mua i nā hopena maikaʻi loa.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Aflibercept

He Palekana ʻo Aflibercept no ka poʻe me ka maʻi diabetes?

ʻAe, palekana ʻo aflibercept no ka poʻe me ka maʻi diabetes a hoʻohana pinepine ʻia e mālama i nā pilikia o ka maka diabetic. Nui ka poʻe e loaʻa ana i nā injections aflibercept i ka maʻi diabetes, a hiki i ka lāʻau lapaʻau ke kōkua i ka pale ʻana i ka nalowale ʻana o ka ʻike i hana ʻia e ka retinopathy diabetic a me ka edema macular diabetic.

Eia naʻe, ʻo ka loaʻa ʻana o ka maʻi diabetes, ʻo ia hoʻi e nānā pono kāu kauka iā ʻoe i ka wā o ka mālama ʻana. Hiki i nā pae kiʻekiʻe o ke kō koko ke hoʻopilikia i ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau a hiki ke hoʻonui i ka pilikia o nā pilikia.

He mea nui e mālama i kāu mau pae kō koko e like me ka hiki i ka wā e loaʻa ana nā injections aflibercept. Kōkua kēia i ka lāʻau lapaʻau e hana ʻoi aku ka maikaʻi a hoʻemi i ka pilikia o ka hōʻino ʻana o kou maʻi maka.

He aha kaʻu e hana ai inā e hala wau i kahi mahele o Aflibercept?

Inā e hala ʻoe i kāu injection aflibercept i hoʻonohonoho ʻia, e hoʻokaʻaʻike i ke keʻena o kāu kauka maka i ka hiki wawe e hoʻonohonoho hou. Mai kali a hiki i kāu manawa i hoʻonohonoho mau ʻia, no ka mea, ʻo ka hoʻopaneʻe ʻana i ka mālama ʻana hiki ke ʻae i kou maʻi maka e hōʻino.

Makemake ka hapa nui o nā kauka e hoʻihoʻi iā ʻoe i ka papa hana i loko o hoʻokahi a ʻelua pule paha o kāu manawa i hala. Aia ka manawa kikoʻī i ka lōʻihi o ka hala ʻana mai kāu injection hope loa a me ke ʻano o ka pane ʻana o kou maka i ka mālama ʻana.

E hoʻāʻo e hoʻololi i ka manawa i ka wā e ʻike ai ua hala ʻoe i kāu manawa. Loaʻa i kekahi mau keʻena maka nā papa inoa hoʻopau a hiki ke hoʻokomo iā ʻoe i loko o ka manawa koke inā hoʻopau kekahi i kā lākou manawa.

He aha kaʻu e hana ai inā loaʻa iaʻu nā hopena ʻaoʻao koʻikoʻi?

Inā loaʻa iā ʻoe nā hopena ʻaoʻao koʻikoʻi e like me ka nalowale ʻana o ka ʻike koke, ka ʻeha maka nui, a i ʻole nā ​​hōʻailona o ka maʻi, e kelepona koke i kāu kauka maka a i ʻole e hele i ka lumi pilikia. Pono kēia mau hōʻailona i ka nānā ʻana i ka lāʻau lapaʻau e pale ai i ka pōʻino mau.

No nā hopena ʻaoʻao liʻiliʻi e like me ka hōʻoluʻolu maka māmā a i ʻole ka ʻike pōʻeleʻele manawa, hiki iā ʻoe ke mālama iā lākou ma ka home me nā waimaka hana ʻole i ka mālama ʻana a me nā mea hōʻoluʻolu ʻeha ma luna o ka pāʻani e like me ka mea e pono ai.

E mālama i ka ʻike pili o kāu kauka ma hope o nā hola, no ka mea, he nui nā keʻena maka i nā laina kelepona pilikia no nā kūlana koʻikoʻi. Ke kānalua, ʻoi aku ka maikaʻi o ke kelepona a nānā ma mua o ke kali a me ka pilikia o nā pilikia.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Aflibercept?

ʻO ka hoʻoholo e hooki i ka mālama ʻana iā aflibercept e hana mau ʻia ma ke kūkākūkā ʻana me kāu kauka maka. Pono ka hapa nui o nā kānaka me nā maʻi e like me ka degeneration macular pulu a i ʻole ka maʻi maka diabetic i ka mālama mau ʻana e mālama i kā lākou hoʻomaikaʻi ʻike.

E loiloi mau kāu kauka i ke ʻano o ka pane ʻana o kou maka i ka lāʻau lapaʻau a hiki ke hoʻolōʻihi mālie i ka manawa ma waena o nā injections inā paʻa kou kūlana. Eia naʻe, ʻo ka hoʻōki ʻana i ka mālama ʻana e alakaʻi pinepine i ka hoʻi ʻana mai o ka wai a me nā pilikia ʻike.

Hiki i kekahi poʻe ke hiki ke hoʻomaha mai ka mālama ʻana inā lilo kā lākou maʻi maka i mea ʻole, akā pono kēia i ka nānā pono ʻana. E hoʻohana kāu kauka i nā hoʻokolohua kiʻi kūikawā e hoʻoholo ai inā a i ka manawa e palekana ai ke hoʻomaha i ka mālama ʻana.

Hiki iaʻu ke kalaiwa ma hope o ka loaʻa ʻana o kahi injection Aflibercept?

ʻAʻole pono ʻoe e kalaiwa koke ma hope o ka loaʻa ʻana o ka aflibercept injection, no ka mea, e pōpō paha kou ʻike no ka manawa pōkole mai nā kulu hoʻopā a me ka injection ponoʻī. Manaʻo ka hapa nui o nā kauka e hoʻonohonoho i kekahi e kalaiwa iā ʻoe i ka home ma hope o kāu manawa.

Hoʻi maʻamau kou ʻike i ka maʻamau i loko o kekahi mau hola ma hope o ka injection, akā hiki ke ʻokoʻa kēia mai kēlā kanaka i kēia kanaka. Ua ʻoluʻolu kekahi poʻe e kalaiwa i ka lā aʻe, a ʻoi aku ka makemake o kekahi e kali iki.

E hoʻolālā e loaʻa ka halihali i hoʻonohonoho ʻia no kāu mau manawa injection, a mai hoʻonohonoho i nā hana nui e koi ana i ka ʻike maopopo no ke koena o ka lā. Hiki i ka hapa nui o nā kānaka ke hoʻomau i nā hana maʻamau, me ke kalaiwa ʻana, i loko o 24 mau hola o kā lākou injection.