He aha ʻo Aflibercept (Eylea): Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau ʻo Aflibercept e kōkua ana i ka mālama ʻana i nā maʻi maka koʻikoʻi e hiki ke alakaʻi i ka nalowale o ka ʻike. Hāʻawi ʻia ia ma ke ʻano he injection pololei i loko o kou maka e ālai i nā protein ʻino e hōʻino i nā kīʻaha koko i loko o kou retina.

Hana kēia lāʻau lapaʻau e like me ka pale, e pale ana i ka ʻiʻo palupalu ma ke kua o kou maka mai ka pōʻino hou aku. Nui ka poʻe i ʻike he mea kōkua ia i ka mālama ʻana i ko lākou ʻike a, i kekahi mau hihia, hoʻomaikaʻi i ko lākou ʻike ke hana ʻole nā ​​lāʻau lapaʻau ʻē aʻe.

He aha ʻo Aflibercept?

He protein i hana ʻia e ke kanaka ʻo Aflibercept e hoʻohālike i ka hiki maoli o kou kino e pale aku i nā mea ʻino i kou maka. No ka papa o nā lāʻau lapaʻau i kapa ʻia ʻo anti-VEGF drugs, ʻo ia hoʻi, e ālai ana i kahi protein i kapa ʻia ʻo vascular endothelial growth factor.

E noʻonoʻo iā VEGF ma ke ʻano he hōʻailona e haʻi ana i kou kino e ulu i nā kīʻaha koko hou. ʻOiai he mea kōkua kēia hana i ka hoʻōla ʻana i nā ʻeha, hiki iā ia ke hana i nā pilikia i kou maka ke hana ia ma kahi hewa a i ʻole i ka manawa hewa.

Hele mai ka lāʻau lapaʻau ma ke ʻano he hopena maopopo e hoʻokomo pololei ai kāu kauka maka i loko o ka mea gel-like i loko o kou maka. ʻO kēia ala i manaʻo ʻia, ʻo ia hoʻi, hele ka lāʻau lapaʻau i kahi e pono ai, me ka hoʻopilikia ʻole i ke koena o kou kino e like me nā pills.

No ke aha i hoʻohana ʻia ai ʻo Aflibercept?

Hoʻomaʻamaʻa ʻo Aflibercept i kekahi mau maʻi maka e pili ana i ka ulu ʻana o nā kīʻaha koko ʻino a i ʻole ke kahe ʻana i loko o kou retina. Hiki i kāu kauka ke ʻōlelo iā ia inā loaʻa iā ʻoe ka degeneration macular e pili ana i ka makahiki, e pili ana i kou ʻike waena.

Kōkua pū ka lāʻau lapaʻau i ka poʻe me ka edema macular diabetic, kahi pilikia o ka maʻi diabetes kahi e kūkulu ai ka wai i waenakonu o kou retina. Hiki i kēia pehu ke hoʻopōpō a i ʻole ke hoʻopilikia i kou ʻike, ʻoi aku ka nui ke hoʻāʻo nei ʻoe e heluhelu a i ʻole e ʻike i nā kikoʻī maikaʻi.

ʻO nā maʻi ʻē aʻe e pane maikaʻi ana i ka aflibercept, ʻo ia ka maʻi maʻi diabetic a me ka pani ʻana o ka vein retinal. Hoʻopilikia kēia mau maʻi i nā kīʻaha koko i loko o kou retina, hiki ke alakaʻi i nā pilikia o ka ʻike inā ʻaʻole i mālama ʻia.

Loaʻa nō hoʻi i kekahi poʻe ka aflibercept no ka myopic choroidal neovascularization, kahi maʻi e ulu ai nā kīʻaha koko hou ma lalo o ka retina i ka poʻe me ka nearsightedness koʻikoʻi. E hoʻoholo kāu kauka maka inā kūpono kēia lapaʻau no kou kūlana.

Pehea e Hana ai ʻo Aflibercept?

Hana ʻo Aflibercept ma ka pale ʻana i ka VEGF, kahi protein e hoʻoulu ai i nā kīʻaha koko e ulu a kahe i ka wai. Ke loaʻa iā ʻoe kekahi mau maʻi maka, hana kou kino i ka nui o ka VEGF, e alakaʻi ana i ka ulu ʻana o nā kīʻaha koko i makemake ʻole ʻia i loko o kou retina.

He palupalu kēia mau kīʻaha koko ʻano ʻē a maʻa mau e kahe i ke koko a me ka wai i loko o kou maka. Hiki i kēia kahe ke hoʻoulu i ka pehu, ka ʻōpala, a me ka nalowale o ka ʻike i ka manawa.

Ma ka pale ʻana i ka VEGF, kōkua ʻo aflibercept i ka hōʻemi ʻana i kēia ulu ʻana o nā kīʻaha koko ʻano ʻē a hoʻemi i ka kahe ʻana o ka wai. Hiki i kēia kaʻina hana ke kōkua i ka hoʻopaʻa ʻana i kou ʻike a, i nā hihia he nui, hoʻomaikaʻi iā ia.

Ua manaʻo ʻia ʻo Aflibercept he lāʻau lapaʻau ikaika a maikaʻi hoʻi no kēia mau maʻi. ʻIke ka hapa nui o nā kānaka i ka hoʻomaikaʻi ʻana i ko lākou ʻike i loko o nā mahina mua o ka lapaʻau, ʻoiai hiki ke ʻokoʻa nā hopena mai kēlā kanaka i kēia kanaka.

Pehea e Lawe ai au i ka Aflibercept?

Hāʻawi ʻia ʻo Aflibercept ma ke ʻano he injection pololei i loko o kou maka ma ke keʻena o kāu kauka. ʻAʻole ʻoe e lawe i kēia lāʻau ma ka home, a ʻaʻole pono ʻoe e hopohopo e pili ana i ka hoʻomanaʻo ʻana e lawe i nā pila a i ʻole ka hoʻomākaukau ʻana i nā meaʻai kūikawā.

Ma mua o kāu injection, e hoʻomaʻemaʻe kāu kauka i kou maka a me ka wahi a puni me ka antiseptic e pale ai i ka maʻi. E hāʻawi pū lākou iā ʻoe i nā kulu numbing e hana i ke kaʻina hana e like me ka ʻoluʻolu.

He mau kekona wale nō ka hoʻokomo ʻana i ka lāʻau, akā, hiki i ka manawa a pau ke 30 a 60 mau minuke. Hiki iā ʻoe ke ʻai maʻamau ma mua o kāu manawa, a ʻaʻole pono ʻoe e pale i nā meaʻai a i ʻole nā mea inu.

Ma hope o kāu hoʻokomo ʻana i ka lāʻau, hiki iā ʻoe ke ʻike i kekahi ʻoluʻolu iki a i ʻole e ʻike i kekahi mau kiko lana i kou ʻike. He maʻamau kēia mau hopena a maʻa mau e hala i loko o hoʻokahi a ʻelua paha lā.

E hoʻonohonoho kāu kauka i kāu mau manawa ukali, a he mea nui e mālama i nā mea a pau inā paʻa kou ʻike. Kōkua ka nānā mau ʻana i ka hōʻoia ʻana e hana pono ana ka lapaʻau.

Pehea ka lōʻihi e lawe ai au i ka Aflibercept?

Pono ka hapa nui o nā kānaka i nā injections aflibercept no nā mahina a i ʻole nā makahiki, ma muli o ko lākou kūlana kikoʻī a me ka maikaʻi o kā lākou pane ʻana i ka lapaʻau. E hana kāu kauka maka i kahi hoʻolālā lapaʻau i hoʻopilikino ʻia i kāu mau pono.

I ka wā mua, e loaʻa paha iā ʻoe nā injections i kēlā me kēia mahina a i ʻole i kēlā me kēia mahina ʻē aʻe no nā mahina mua. Kōkua kēia papa manawa pinepine i ka hoʻomalu ʻana i kou kūlana.

Ke paʻa kou ʻike, hiki i kāu kauka ke hoʻokaʻawale i kāu mau injections i kēlā me kēia ʻelua a ʻekolu paha mahina. Hiki i kekahi poʻe ke hele lōʻihi ma waena o nā lapaʻau.

ʻO ka pahuhopu ka loaʻa ʻana o ke kaulike kūpono ma waena o ka mālama ʻana i ka hoʻomaikaʻi ʻana i kou ʻike a me ka hōʻemi ʻana i ka helu o nā injections āu e pono ai. E nānā pono kāu kauka i kāu holomua a hoʻoponopono i kāu papa manawa lapaʻau e like me ka mea e pono ai.

Pono paha kekahi poʻe i ka lapaʻau mau loa e mālama i ko lākou ʻike, a hiki i nā poʻe ʻē aʻe ke hooki ma hope o ka paʻa ʻana o ko lākou kūlana. E hoʻoholo kāu kūlana pilikino i ke ala maikaʻi loa.

He aha nā hopena ʻaoʻao o Aflibercept?

E like me nā lāʻau lapaʻau a pau, hiki i ka aflibercept ke hana i nā hopena ʻaoʻao, akā, ʻae ka hapa nui o nā kānaka iā ia. ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a pili i ke kaʻina hana injection.

Eia nā hopena ʻaoʻao e hiki iā ʻoe ke ʻike, e hoʻomaka ana me nā mea maʻamau e hoʻoponopono pinepine iā lākou iho:

• ʻEha maka māmā a i ʻole ka hōʻoluʻolu ʻole no hoʻokahi a ʻelua paha lā ma hope o ka injection
• Nā kiko liʻiliʻi o ke koko ma ka ʻāpana keʻokeʻo o kou maka (conjunctival hemorrhage)
• Nā kiko lana manawa i kou ʻike
• Ke manaʻo nei me he mea lā aia kekahi mea i kou maka
• ʻUlaʻula maka māmā a i ʻole ka huhū
• Hoʻonui manawa i ke kaomi maka
• Maka maloʻo a i ʻole ka hana waimaka nui

ʻO kēia mau hopena ʻaoʻao maʻamau he māmā maʻamau a ʻaʻole pono e mālama ʻia. Hoʻomaikaʻi maʻamau lākou i loko o kekahi mau lā i ka wā e hoʻōla ai kou maka mai ka injection.

Hiki ke loaʻa nā hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi, ʻoiai e pili ana lākou i ka liʻiliʻi ma mua o 1 i ka 100 poʻe. Aia kēia mau mea i ka maʻi maka, ka mumū nui i loko o ka maka, ka wehe ʻana o ka retina, a i ʻole ka piʻi nui ʻana o ke kaomi maka.

ʻO nā pilikia kakaʻikahi loa akā koʻikoʻi e pili ana i nā hopena maʻi maʻi koʻikoʻi a i ʻole nā ​​koko koko. ʻOiai he mea maʻamau ʻole kēia mau mea, e nānā kāu kauka iā ʻoe no nā hōʻailona o kēia mau kūlana.

Inā ʻike ʻoe i ka ʻeha maka nui, nā loli ʻike koke, a i ʻole nā ​​hōʻailona o ka maʻi e like me ka ʻulaʻula a me ka hoʻokuʻu ʻana, e kelepona koke i kāu kauka. Hiki i kēia mau hōʻailona ke hōʻike i kahi pilikia koʻikoʻi e pono ai ka nānā koke.

ʻO wai ka mea ʻaʻole pono e lawe iā Aflibercept?

ʻAʻole kūpono ʻo Aflibercept no nā mea a pau, a e loiloi pono kāu kauka inā palekana ia iā ʻoe. ʻAʻole pono ka poʻe me nā maʻi maka ikaika e loaʻa ka injection a hiki i ka pau ʻana o ka maʻi.

Inā loaʻa iā ʻoe ka mumū nui i loko a i ʻole a puni kou maka, e mālama paha kāu kauka i kēia maʻi ma mua o ka noʻonoʻo ʻana iā aflibercept. Hiki i ka lāʻau lapaʻau ke hoʻonui i ka mumū.

ʻO ka poʻe me nā maʻi maʻi i ʻike ʻia iā aflibercept a i ʻole kekahi o kāna mau mea pono e pale i kēia lapaʻau. E nānā kāu kauka i kāu mōʻaukala maʻi ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau.

Pono nā maʻi lapaʻau kekahi e mālama nui ʻia, ʻoiai ʻaʻole lākou e kāpae koke i ka mālama ʻana me ka aflibercept. Inā he moʻolelo kou o ka hahau ʻana, ka puʻuwai, a i ʻole nā ʻōpū koko, e loiloi kāu kauka i nā pilikia a me nā pōmaikaʻi me ka akahele.

Pono nā wāhine hāpai e pale i ka aflibercept ke ʻole ka maikaʻi o nā pōmaikaʻi i nā pilikia. Inā ʻoe e hoʻolālā ana e hāpai a i ʻole e hānai ana i ka waiū, e kūkākūkā i kēia me kāu kauka.

Pono ka poʻe e lawe ana i nā mea lahilahi koko a i ʻole ka poʻe me nā maʻi koko e nānā pono ʻia, no ka mea, hiki i kēia mau maʻi ke hoʻonui i ka pilikia o ke kahe koko i ka wā a i ʻole ma hope o ka injection.

Nā inoa inoa o Aflibercept

ʻIke nui ʻia ʻo Aflibercept ma kona inoa inoa ʻo Eylea. ʻO kēia ka mana i hana kūikawā ʻia no nā injections maka i loaʻa i ka hapa nui o nā kānaka.

Hiki nō hoʻi iā ʻoe ke lohe i kāu kauka e kuhikuhi ana iā ia ma ke ʻano he aflibercept-VEGF Trap, e wehewehe ana i ke ʻano o ka hana ʻana o ka lāʻau. Hoʻohana kekahi poʻe loea lapaʻau i ka inoa generic piha aflibercept i ke kūkākūkā ʻana i nā koho lapaʻau.

Aia kekahi mana i kapa ʻia ʻo Zaltrap, akā he ʻano ʻokoʻa kēia i hoʻohana ʻia no ka mālama ʻana i ka maʻi kanesa, ʻaʻole nā maʻi maka. E hōʻoia i kāu kauka e kuhikuhi ana i ka mana kūpono no kou maʻi maka.

Nā koho ʻē aʻe o Aflibercept

He nui nā lāʻau lapaʻau ʻē aʻe e hana like me ka aflibercept no ka mālama ʻana i nā maʻi maka. ʻO nā koho maʻamau e pili ana i ka ranibizumab (Lucentis) a me bevacizumab (Avastin).

Pale kēia mau lāʻau lapaʻau i ka VEGF e like me ka aflibercept, akā he ʻano ʻokoʻa iki ko lākou a me nā papa hana dosing. Ua pane maikaʻi kekahi poʻe i kekahi lāʻau ma mua o kekahi.

Hiki i kāu kauka ke ʻōlelo aku e hoʻāʻo i kahi lāʻau anti-VEGF ʻē aʻe inā ʻaʻole hana maikaʻi ka aflibercept iā ʻoe a i ʻole inā loaʻa iā ʻoe nā hopena ʻaoʻao. Hiki ke ʻokoʻa ka pane ʻana o kēlā me kēia kanaka i kēia mau lāʻau.

I kekahi mau hihia, hiki i kāu kauka ke ʻōlelo e hui pū ʻoe i ka aflibercept me nā lāʻau lapaʻau ʻē aʻe e like me ka lāʻau laser a i ʻole nā ​​injections steroid. Aia ke ala maikaʻi loa i kāu kūlana kikoʻī a me ka maikaʻi o kou pane ʻana i ka lāʻau mua.

Ua ʻoi aku ka maikaʻi o ka Aflibercept ma mua o Ranibizumab (Lucentis)?

He mau lāʻau lapaʻau maikaʻi loa ʻo Aflibercept a me ranibizumab no ka mālama ʻana i nā maʻi maka e pili ana i ka ulu ʻana o nā kīʻaha koko ʻokoʻa. Hōʻike nā haʻawina e hiki i nā lāʻau lapaʻau ʻelua ke hoʻomaikaʻi nui i ka ʻike a me ka lohi ʻana i ka holomua o ka maʻi.

ʻO ka ʻokoʻa nui ʻo ka aflibercept e lōʻihi paha i kou maka, ʻo ia hoʻi, pono paha ʻoe i nā injections liʻiliʻi i ka manawa. Nui ka poʻe hiki ke hoʻokaʻawale i kā lākou mau injections aflibercept i kēlā me kēia mahina ʻelua ma hope o ka manawa lapaʻau mua.

Pono maʻamau ʻo Ranibizumab i nā injections i kēlā me kēia mahina i ka wā mua, ʻoiai hiki i kekahi poʻe ke hoʻolōʻihi i ka manawa ma waena o nā lāʻau lapaʻau ke paʻa ke kūlana. Loaʻa i nā lāʻau lapaʻau ʻelua nā ʻano palekana like a me nā helu hopena ʻaoʻao.

E noʻonoʻo kāu kauka i nā mea e like me kāu maʻi maka kikoʻī, kou ola, a me kāu ʻinikua i ke koho ʻana ma waena o kēia mau koho. ʻO ka mea nui ka loaʻa ʻana o ka lāʻau lapaʻau e hana maikaʻi loa no kāu kūlana pilikino.

Nā Nīnau i Nīnau pinepine ʻia e pili ana i ka Aflibercept

He palekana anei ʻo Aflibercept no ka maʻi diabetes?

ʻAe, palekana ka aflibercept no ka poʻe me ka maʻi diabetes a hoʻohana pinepine ʻia e mālama i nā pilikia o ka maka diabetic. Kōkua maoli ka lāʻau lapaʻau me ka edema macular diabetic a me ka retinopathy diabetic.

E nānā kāu kauka i kāu pae kōpaʻa koko a me ka mālama ʻana i ka maʻi diabetes ma ka ʻaoʻao o kāu lāʻau maka. Hiki i ka mana maikaʻi o ka maʻi diabetes ke kōkua i ka hana ʻana i ka aflibercept ʻoi aku ka maikaʻi a hoʻemi i ka pilikia o nā pilikia o ka maka.

He aha kaʻu e hana ai inā hoʻohana hewa au i ka nui o ka Aflibercept?

Mai ka mea e hāʻawi ʻia ai ka aflibercept ma ke ʻano he ʻinikini ma ke keʻena o kāu kauka, ʻaʻole hiki iā ʻoe ke lawe nui loa ma ka home. Ana pono kāu kauka i ka nui pololei no kēlā me kēia ʻinikini.

Inā hopohopo ʻoe e pili ana i kāu ʻinikini a i ʻole e ʻike i nā hōʻailona maʻamau ma hope o ka mālama ʻana, e kelepona koke i kāu kauka maka. Hiki iā lākou ke loiloi i kāu mau hōʻailona a hoʻoholo inā pono ka mālama hou.

He aha kaʻu e hana ai inā e hala wau i kahi mahele o Aflibercept?

Inā hala ʻoe i kahi ʻinikini aflibercept i hoʻonohonoho ʻia, e kelepona i ke keʻena o kāu kauka i ka hiki wawe e hoʻonohonoho hou. E hoʻāʻo e kiʻi i kāu ʻinikini kokoke i ka papa hana mua e like me kāu e hiki ai.

ʻO ka hala ʻana i hoʻokahi ʻinikini ʻaʻole ia e hōʻeha mau, akā hiki ke hoʻolohi i kāu holomua a i ʻole e ʻae i kou kūlana e ʻino no ka manawa. Pono paha kāu kauka e hoʻoponopono i kāu hoʻolālā lapaʻau e pili ana i ka lōʻihi o kou noho ʻole ʻana me ka lapaʻau.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Aflibercept?

Aia ka hoʻoholo e hooki i ka lapaʻau aflibercept i ka maikaʻi o ka mālama ʻia ʻana o kou maʻi maka a me kāu pane pilikino i ka lāʻau. Pono kekahi poʻe i ka lapaʻau mau e mālama i kā lākou hoʻomaikaʻi ʻike.

E loiloi mau kāu kauka i kāu holomua me ka hoʻohana ʻana i nā hoʻokolohua maka a me nā hoʻokolohua kiʻi. Inā paʻa kou kūlana no ka manawa lōʻihi, hiki iā lākou ke kūkākūkā i ka hoʻokaʻawale ʻana i nā ʻinikini a i ʻole ke hooki ʻana i ka lapaʻau.

Mai hooki i ka lapaʻau aflibercept ma kāu iho me ka kūkākūkā ʻole ʻana me kāu kauka mua. ʻO ka hooki ʻana i ka wā mua hiki ke alakaʻi i ka hoʻi ʻana mai o nā hōʻailona a me ka nalowale ʻana o ka ʻike.

Hiki iaʻu ke kalaiwa ma hope o ka loaʻa ʻana o kahi ʻinikini Aflibercept?

Hiki iā ʻoe ke ʻike i nā loli ʻike no ka manawa pōkole ma hope koke o kāu ʻinikini, me ka ʻike pohihihi a i ʻole nā ​​kiko lana. Manaʻo ka hapa nui o nā kauka e loaʻa i kekahi e kalaiwa iā ʻoe i ka home ma hope o kāu manawa.

E maikaʻi pinepine ana kēia mau hopena i loko o kekahi mau hola, akā ʻoi aku ka maikaʻi o ka pale ʻana i ka hoʻokele a hiki i ka wā e hoʻi ai kou ʻike i ke ʻano maʻamau. E hoʻolālā e hoʻomaha i ke koena o ka lā a pale i nā hana e koi ai i ka ʻike maopopo.