He aha ʻo Aliskiren: Nā Hoʻohana, Ka Laʻau, Nā ʻAoʻao ʻino a me nā mea hou aku

He lāʻau lapaʻau ʻo Aliskiren e kōkua ana i ka hoʻohaʻahaʻa ʻana i ke koko kiʻekiʻe ma ka pale ʻana i kahi enzyme kikoʻī i loko o kou kino. No kahi papa kū hoʻokahi o nā lāʻau lapaʻau koko kiʻekiʻe i kapa ʻia he direct renin inhibitors, e hana ana i nā ʻano like ʻole mai nā lāʻau lapaʻau koko kiʻekiʻe maʻamau āu i lohe ai.

Hiki i kēia lāʻau lapaʻau ke lilo i mea hana pono i ka mālama ʻana i ka hypertension i ka wā i hana ʻole ai nā lāʻau lapaʻau ʻē aʻe ma kā lākou iho. Hiki i kāu kauka ke kuhikuhi iā aliskiren ma ke ʻano he ʻāpana o kahi ala piha e pale ai i kou puʻuwai a me nā kīʻaha koko mai nā hopena lōʻihi o ke koko kiʻekiʻe.

He aha ʻo Aliskiren?

He lāʻau lapaʻau koko kiʻekiʻe ʻo Aliskiren e hana ana ma ka pale ʻana i ka renin, kahi enzyme e hana ai kou mau puʻupaʻa. E noʻonoʻo i ka renin ma ke ʻano he domino mua i loko o kahi kaulahao e hoʻokiʻekiʻe ai i kou koko.

ʻAʻole like me nā lāʻau lapaʻau koko kiʻekiʻe ʻē aʻe e hana ma hope o kēia kaulahao, hoʻōki ʻo aliskiren i ke kaʻina hana ma ka hoʻomaka. He mea pono loa kēia no ka poʻe e pono ai i kahi ala ʻokoʻa i ka mālama ʻana i ke koko.

Hele mai ka lāʻau lapaʻau ma ke ʻano o ka papa a lawe ʻia i hoʻokahi manawa i ka lā. Ua hoʻolālā ʻia no ka hoʻohana lōʻihi ma ke ʻano he ʻāpana o ka mālama ʻana i ke koko, ʻaʻole ma ke ʻano he hoʻoponopono wikiwiki no nā helu kiʻekiʻe.

No ke aha e hoʻohana ʻia ai ʻo Aliskiren?

Hoʻohana nui ʻia ʻo Aliskiren no ka mālama ʻana i ke koko kiʻekiʻe (hypertension) i nā pākeke. Hiki i kāu kauka ke kuhikuhi iā ia i ka wā e helu mau ai kou koko i ka 140/90 mmHg a i ʻole ke kiʻekiʻe, a i ʻole i ka wā i hoʻohaʻahaʻa ʻole ai nā lāʻau lapaʻau ʻē aʻe i kāu mau helu.

Hoʻohana pinepine ʻia kēia lāʻau lapaʻau ke pono ʻoe i ka mana koko hou aʻe ma mua o ka mea āu e loaʻa nei mai nā lāʻau lapaʻau ʻē aʻe. Hiki ke hoʻohana ʻia wale nō a i hui pū ʻia me nā lāʻau lapaʻau koko kiʻekiʻe ʻē aʻe e like me nā diuretics a i ʻole calcium channel blockers.

I kekahi manawa, kuhikuhi nā kauka i ka aliskiren no ka poʻe i loaʻa nā hopena ʻaoʻao mai nā lāʻau lapaʻau koko kiʻekiʻe ʻē aʻe. No ka mea, hana ia ma o kahi ʻano hana ʻokoʻa, ʻoi aku paha ka maikaʻi o kekahi poʻe maʻi.

Pehea e Hana ai ʻo Aliskiren?

Hana ʻo Aliskiren ma ka pale ʻana i ka renin, he enzyme e hoʻokuʻu ai kou mau puʻupaʻa ke ʻike lākou i ke koko haʻahaʻa a i ʻole ke kahe koko i hōʻemi ʻia. Ua manaʻo ʻia he lāʻau lapaʻau koko kiʻekiʻe ikaika e manaʻo ana i ke kumu o hoʻokahi ala koko kiʻekiʻe nui.

Ke ālai ʻia ka renin, ʻaʻole hiki iā ia ke hoʻomaka i ke kaʻina e hana ai i ka angiotensin II, he mea ikaika e hoʻopaʻa ai i nā kīʻaha koko a hoʻokiʻekiʻe i ke koko. Ma ka hoʻōki ʻana i kēia kaʻina hana i ka wā mua, kōkua ʻo aliskiren e mālama i kou mau kīʻaha koko e hoʻomaha.

Hoʻomaka ka lāʻau lapaʻau e hana i loko o nā hola o ka lawe ʻana, akā ʻaʻole paha ʻoe e ʻike i nā hopena piha no kekahi mau pule. He mea maikaʻi maoli kēia hana mālie no ka mea e hiki ai i kou kino ke hoʻoponopono mālie i nā pae koko haʻahaʻa.

Pehea e Lawe ai au i ka Aliskiren?

E lawe i ka aliskiren e like me ke kauoha a kāu kauka, maʻamau hoʻokahi manawa i ka lā i ka manawa like i kēlā me kēia lā. Hiki iā ʻoe ke lawe me ka ʻole o ka meaʻai, akā e hoʻāʻo e kūlike me kāu koho e mālama i nā pae paʻa i loko o kou kino.

E ale i ka papa holoʻokoʻa me ke aniani wai piha. Mai ʻoki, nau, a haki paha i ka papa, no ka mea, hiki i kēia ke hoʻopilikia i ke ʻano o ka hoʻokuʻu ʻia ʻana o ka lāʻau lapaʻau i loko o kou kino.

Inā ʻoe e lawe ana i ka aliskiren me ka meaʻai, e pale i nā meaʻai momona nui no ka mea hiki iā lākou ke hōʻemi i ka maikaʻi o kou kino e komo i ka lāʻau lapaʻau. ʻOi aku ka maikaʻi o nā meaʻai māmā a i ʻole ka lawe ʻana ma ka ʻōpū ʻole no ka absorption maikaʻi loa.

E hoʻāʻo e lawe i kāu mahele i ka manawa like i kēlā me kēia lā e kōkua iā ʻoe e hoʻomanaʻo a e mālama i nā pae paʻa o ka lāʻau lapaʻau i loko o kāu ʻōnaehana. Nui ka poʻe i ʻike he mea kōkua ke lawe me kā lākou hana kakahiaka.

Pehea ka lōʻihi e lawe ai au i ka Aliskiren?

Hoʻohana pinepine ʻia ʻo Aliskiren no ka manawa lōʻihi, pinepine no nā mahina a i ʻole nā makahiki, no ka mea, he maʻi maʻi maʻamau ka maʻi koko kiʻekiʻe e pono ai ka mālama mau. E hoʻoholo kāu kauka i ka lōʻihi kūpono e pili ana i kāu pane pilikino a me ke olakino holoʻokoʻa.

Mai hooki koke i ka lawe ʻana iā aliskiren, ʻoiai inā ʻoe e ʻoi aku ka maikaʻi a i ʻole e hoʻomaikaʻi nā heluhelu koko. ʻAʻohe hōʻailona pinepine o ke koko kiʻekiʻe, no laila ʻaʻole ia he manaʻo e hiki iā ʻoe ke hooki i ka lāʻau.

E nānā mau kāu kauka i kou koko a me ka hana o ka puʻupaʻa i ka wā e lawe ana ʻoe iā aliskiren. Ma muli o kēia mau nānā ʻana, hiki iā lākou ke hoʻoponopono i kāu mahele a i ʻole e hoʻololi iā ʻoe i kahi hoʻolālā lapaʻau ʻē aʻe.

Pono paha kekahi poʻe e lawe i ka lāʻau lapaʻau koko no ke ola, ʻoiai hiki i nā poʻe ʻē aʻe ke hōʻemi a i ʻole ke hooki inā hoʻomaikaʻi nui nā loli o ke ola i ko lākou olakino cardiovascular.

He aha nā hopena ʻaoʻao o Aliskiren?

E like me nā lāʻau lapaʻau a pau, hiki i ka aliskiren ke hoʻoulu i nā hopena ʻaoʻao, ʻoiai he nui ka poʻe e ʻae maikaʻi iā ia. ʻO ka hapa nui o nā hopena ʻaoʻao he maʻalahi a maʻa mau e hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lāʻau.

Eia nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike:

• Pāpaʻa a i ʻole nā noho palupalu
• ʻO ka noʻonoʻo ʻole, ʻoi loa i ka wā e kū koke ai
• Luhi a i ʻole ka luhi
• ʻEha poʻo
• Nausea a i ʻole ka ʻōpū
• ʻEha hope
• Ua

Hoʻoponopono maʻamau kēia mau hopena ʻaoʻao maʻamau i loko o kekahi mau pule i ka wā e hoʻoponopono ai kou kino i ka lāʻau. Inā mau lākou a i ʻole e lilo i mea pilikia, e kamaʻilio me kāu kauka e pili ana i ka hoʻoponopono ʻana i kāu mahele a i ʻole ka manawa.

Aia kekahi mau hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi e pono ai ka lāʻau lapaʻau koke:

• Ka wili nui a i ʻole ka nāwaliwali
• Ka pehu ʻana o ka maka, nā lehelehe, ke alelo, a i ʻole ka ʻāʻī
• He paʻakikī ka hanu ʻana a i ʻole ka ʻai ʻana
• Ka ʻōpala ʻili a i ʻole nā hives
• Ka puʻuwai wikiwiki a i ʻole ka puʻuwai ʻole
• Ka ʻeha nui o ka ʻōpū
• Nā hōʻailona o nā pilikia o ka puʻupaʻa (nā loli i ka mimi, ka pehu ʻana o nā wāwae a i ʻole nā wāwae)

E kelepona koke i kāu mea mālama ola inā ʻike ʻoe i kekahi o kēia mau hopena ʻaoʻao koʻikoʻi. ʻOiai he mea maʻamau, hiki iā lākou ke hōʻike i kahi hopena koʻikoʻi e pono ai ka mālama olakino wikiwiki.

ʻO wai ka mea pono ʻole e lawe iā Aliskiren?

ʻAʻole kūpono ʻo Aliskiren no nā mea a pau, a ʻo kekahi mau maʻi olakino a i ʻole nā kūlana e palekana ʻole ai ka hoʻohana ʻana. E nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana i kēia lāʻau.

ʻAʻole pono ʻoe e lawe iā aliskiren inā he maʻi diabetes kāu a ke lawe pū nei ʻoe i nā mea pale ACE a i ʻole ARB (nā ʻano lāʻau lapaʻau koko ʻē aʻe). Hoʻonui nui kēia hui ʻana i ka pilikia o nā pilikia puʻupaʻa koʻikoʻi a me ke koko haʻahaʻa weliweli.

Pono nā poʻe me ka maʻi puʻupaʻa koʻikoʻi a i ʻole ka poʻe ma ka dialysis e pale aku iā aliskiren, no ka mea, hiki iā ia ke hoʻonui i ka hana puʻupaʻa. Pēlā nō, inā he mōʻaukala kou o ka maʻi ate koʻikoʻi, ʻaʻole kūpono paha kēia lāʻau lapaʻau iā ʻoe.

ʻAʻole pono nā wahine hāpai e lawe iā aliskiren, no ka mea, hiki iā ia ke hōʻeha nui i ka pēpē e ulu ana, me nā pilikia o ka puʻupaʻa a me ke koko haʻahaʻa. Inā ʻoe e hoʻolālā nei e hāpai a i ʻole ʻike ʻoe he hāpai ʻoe i ka wā e lawe ana iā aliskiren, e kelepona koke i kāu kauka.

Pono nā makuahine e hānai ana i ka waiū e pale aku iā aliskiren, no ka mea, ʻaʻole ʻike ʻia inā hele ka lāʻau lapaʻau i loko o ka waiū umauma a hiki ke hoʻopilikia i ka pēpē e hānai ana.

Nā inoa inoa ʻo Aliskiren

Loaʻa ʻo Aliskiren ma lalo o ka inoa inoa ʻo Tekturna ma ʻAmelika Hui Pū ʻIa. ʻO kēia ke ʻano i kauoha pinepine ʻia o ka lāʻau lapaʻau a me ka mea āu e ʻike ai ma kāu ʻōmole kauoha.

Aia kekahi lāʻau lapaʻau hui pū ʻia i kapa ʻia ʻo Tekturna HCT, a he aliskiren a me hydrochlorothiazide (he diuretic) i loko. Hoʻohana ʻia kēia hui pū ʻana ke pono nā mea maʻi i nā lāʻau lapaʻau ʻelua e mālama pono i ko lākou koko.

Loaʻa nō hoʻi nā ʻano generic o aliskiren, a he mea like ka mea hana akā ʻoi aku ka liʻiliʻi o ke kumukūʻai ma mua o ka mana inoa inoa. Hiki i kāu kauka lapaʻau ke kōkua iā ʻoe e hoʻomaopopo inā he koho generic kūpono iā ʻoe.

Nā Koho ʻē aʻe o Aliskiren

Inā ʻaʻole kūpono ʻo aliskiren iā ʻoe a i ʻole ʻaʻole hana maikaʻi, aia kekahi mau koho lāʻau lapaʻau koko kiʻekiʻe. Hiki i kāu kauka ke kōkua iā ʻoe e ʻike i ke koho maikaʻi loa e pili ana i kāu mau pono a me ka mōʻaukala olakino.

ʻO nā mea pale ACE e like me lisinopril a i ʻole enalapril he mau lāʻau lapaʻau mua no ke koko kiʻekiʻe. Hana lākou ma ka pale ʻana i kahi ʻanuʻu ʻokoʻa i ke ala like i kā aliskiren e kuhikuhi ai, a nui ka poʻe e ʻae maikaʻi iā lākou.

Hāʻawi nā ARB (Angiotensin Receptor Blockers) e like me losartan a i ʻole valsartan i kahi koho ʻē aʻe. Pale kēia mau lāʻau lapaʻau i nā hopena o angiotensin II ma ka pae receptor a pinepine i nā hopena ʻaoʻao liʻiliʻi ma mua o nā mea pale ACE.

Hana nā mea pale kahawai calcium e like me amlodipine a i ʻole nifedipine ma ka hoʻomaha ʻana i nā kīʻaha koko ma o kahi hana ʻokoʻa loa. He mea maikaʻi loa lākou no ka poʻe i loaʻa i kekahi mau pilikia o ka puʻuwai.

Kōkua nā diuretics (nā pila wai) e like me hydrochlorothiazide i ka hoʻohaʻahaʻa ʻana i ke koko ma ka hoʻemi ʻana i ka nui o ka wai i loko o kou mau kīʻaha koko. Hoʻohana pinepine ʻia lākou me nā lāʻau lapaʻau koko kiʻekiʻe ʻē aʻe no ka mālama maikaʻi ʻana.

ʻOi aku ka maikaʻi o Aliskiren ma mua o Lisinopril?

He mau lāʻau lapaʻau koko kiʻekiʻe maikaʻi ʻo Aliskiren a me lisinopril, akā hana lākou ma o nā hana like ʻole a loaʻa nā pono like ʻole. ʻAʻole ʻoi aku ka maikaʻi o kekahi – ʻo ke koho maikaʻi loa e pili ana i kāu kūlana olakino pilikino a me ke ʻano o kāu pane ʻana i kēlā me kēia lāʻau lapaʻau.

He lāʻau ACE inhibitor ʻo Lisinopril i hoʻohana ʻia no nā makahiki he nui a he nui nā noiʻi e kākoʻo ana i kona pono. Koho pinepine ʻia ʻo ia ma ke ʻano he lapaʻau laina mua no ka mea ua aʻo maikaʻi ʻia, maʻamau i ʻae ʻia, a loaʻa i ke ʻano generic.

Hiki ke makemake ʻia ʻo Aliskiren inā ua loaʻa iā ʻoe nā hopena ʻaoʻao mai nā ACE inhibitors e like me lisinopril, ʻo ia hoʻi ka ʻū maloʻo mau. No ka mea, hana ʻo aliskiren ma mua i ke ala koko, hiki ke ʻoi aku ka maikaʻi no kekahi poʻe.

Eia naʻe, ua hōʻoia ʻia nā pōmaikaʻi o lisinopril ma mua o ka mālama ʻana i ke koko, me ka pale ʻana no ka poʻe me ka puʻuwai puʻuwai a me ka maʻi kīkī e pili ana i ka maʻi diabetes. ʻAʻole nui ka noiʻi ʻana o Aliskiren e kākoʻo ana i kēia mau pōmaikaʻi hou.

E noʻonoʻo kāu kauka i nā mea e like me kou mau maʻi olakino ʻē aʻe, nā lāʻau lapaʻau o kēia manawa, ka mōʻaukala hopena ʻaoʻao, a me ke kumukūʻai i ka wā e hoʻoholo ai ma waena o kēia mau koho. I kekahi manawa, ʻo ka hoʻāʻo ʻana i nā lāʻau lapaʻau ʻelua i ka manawa e kōkua ai i ka hoʻoholo ʻana i ka mea e hana maikaʻi loa ai iā ʻoe.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Aliskiren

He palekana anei ʻo Aliskiren no ka poʻe me ka maʻi diabetes?

Hiki ke hoʻohana palekana ʻia ʻo Aliskiren i ka poʻe me ka maʻi diabetes, akā me nā palena nui. Inā loaʻa iā ʻoe ka maʻi diabetes, ʻaʻole pono ʻoe e lawe iā aliskiren me nā ACE inhibitors a i ʻole ARBs, no ka mea, hoʻonui nui kēia hui i ka pilikia o nā pilikia kīkī a me ke koko haʻahaʻa weliweli.

No ka poʻe me ka maʻi diabetes ʻaʻole e lawe ana i nā ACE inhibitors a i ʻole ARBs, hiki iā aliskiren ke koho maikaʻi no ka mālama ʻana i ke koko. E nānā kāu kauka i kāu hana kīkī, no ka mea, ua kau mua ka maʻi diabetes i ke koʻikoʻi i nā kīkī.

He mea nui nā hoʻokolohua koko maʻamau e nānā i ka hana kīkī a me nā pae potassium ke loaʻa iā ʻoe ka maʻi diabetes a lawe iā aliskiren. Kōkua kēia i ka hopu ʻana i nā pilikia i ka wā mua.

He aha kaʻu e hana ai inā lawe hewa au i ka nui o Aliskiren?

Inā ua lawe ʻoe i ka aliskiren i ʻoi aku ma mua o ka mea i kauoha ʻia, e kelepona koke i kāu kauka a i ʻole ke kikowaena hoʻomalu lāʻau make, ʻoiai inā maikaʻi kou manaʻo. ʻO ka lawe ʻana i ka nui loa hiki ke hoʻohaʻahaʻa i ke koko, ʻaʻole paha e hōʻike koke i nā hōʻailona.

ʻO nā hōʻailona o ka overdose e komo paha i ka wili nui, ka maʻi, ka nausea, a i ʻole ka manaʻo nāwaliwali loa. Inā loaʻa iā ʻoe kēia mau hōʻailona, e ʻimi koke i ka lāʻau lapaʻau.

Mai hoʻāʻo e

ʻOiai he mea maikaʻi paha nā mea liʻiliʻi o ka waiʻona, ʻoi aku ka maikaʻi o ka kaupalena ʻana i ka ʻai ʻana i ka waiʻona i ka wā e lawe ana i ka aliskiren. Hiki i ka waiʻona ke hoʻonui i nā hopena hoʻohaʻahaʻa koko o ka lāʻau lapaʻau, e hiki ai ke hoʻoulu i ka ʻūlū a i ʻole ka hāʻule ʻana o ke koko.

Inā inu ʻoe i ka waiʻona, e hana me ka maʻalahi a e nānā i kou manaʻo. E mālama nui i ka wā e kū ana, no ka mea, ʻo ka hui pū ʻana o ka aliskiren a me ka waiʻona hiki ke hoʻonui i kou pilikia o ka ʻūlū a i ʻole ka hāʻule ʻana.

E kamaʻilio me kāu kauka e pili ana i ka nui o ka ʻai ʻana i ka waiʻona, inā he mea palekana iā ʻoe i ka wā e lawe ana i ka aliskiren. Hiki iā lākou ke hāʻawi i ke alakaʻi pilikino e pili ana i kou olakino holoʻokoʻa a me nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.